scPDB - Distribution of Binding site Similarity values of 4m8h entry / Site 1

PDB ID	HET	Uniprot Name	EC Number
4m8h	R4M	Retinoic acid receptor RXR-alpha

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4m8h	R4M	Retinoic acid receptor RXR-alpha	/	1.000
3oap	REA	Retinoic acid receptor RXR-alpha	/	0.805
4m8e	29V	Retinoic acid receptor RXR-alpha	/	0.780
4k4j	1O8	Retinoic acid receptor RXR-alpha	/	0.656
1fm6	9CR	Retinoic acid receptor RXR-alpha	/	0.651
1xiu	REA	Retinoic acid receptor RXR	/	0.650
1fby	REA	Retinoic acid receptor RXR-alpha	/	0.637
1xls	REA	Retinoic acid receptor RXR-alpha	/	0.635
1k74	9CR	Retinoic acid receptor RXR-alpha	/	0.632
1fm9	9CR	Retinoic acid receptor RXR-alpha	/	0.630
2acl	REA	Retinoic acid receptor RXR-alpha	/	0.626
1rdt	L79	Retinoic acid receptor RXR-alpha	/	0.623
3fal	REA	Retinoic acid receptor RXR-alpha	/	0.608
3uvv	REA	Retinoic acid receptor RXR-alpha	/	0.601
4k6i	9RA	Retinoic acid receptor RXR-alpha	/	0.594
2p1u	4TN	Retinoic acid receptor RXR-alpha	/	0.591
2p1v	5TN	Retinoic acid receptor RXR-alpha	/	0.591
1mzn	BM6	Retinoic acid receptor RXR-alpha	/	0.589
1uhl	MEI	Retinoic acid receptor RXR-beta	/	0.581
3fc6	REA	Retinoic acid receptor RXR-alpha	/	0.580
2p1t	3TN	Retinoic acid receptor RXR-alpha	/	0.579
1mvc	BM6	Retinoic acid receptor RXR-alpha	/	0.557
3h0a	9RA	Retinoic acid receptor RXR-alpha	/	0.548
5d7q	4I5	NAD-dependent protein deacetylase sirtuin-2	3.5.1	0.516
1rd4	L08	Integrin alpha-L	/	0.505
3c0g	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.492
3njo	PYV	Abscisic acid receptor PYR1	/	0.491
3p9t	TCL	Repressor	/	0.491
1hk2	T44	Serum albumin	/	0.490
1pkf	EPD	Epothilone C/D epoxidase	1.14	0.489
3d75	NBB	Pheromone-binding protein ASP1	/	0.489
4lxj	LAN	Lanosterol 14-alpha demethylase	1.14.13.70	0.488
2y98	MIV	Mycinamicin IV hydroxylase/epoxidase	/	0.487
3bjh	NBB	Odorant binding protein ASP1	/	0.487
3h1j	SMA	Cytochrome b	/	0.487
4jx1	CAH	Camphor 5-monooxygenase	1.14.15.1	0.487
4l8u	9AZ	Serum albumin	/	0.487
3ar5	TG1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.486
3byz	H11	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.486
5d7p	OCZ	NAD-dependent protein deacetylase sirtuin-2	3.5.1	0.486
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.485
2qd4	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.484
4ia2	BIV	Vitamin D3 receptor A	/	0.483
3iro	2CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.482
3l0l	HC3	Nuclear receptor ROR-gamma	/	0.481
3qly	55V	Uncharacterized protein	/	0.481
3tk3	CPZ	Cytochrome P450 2B4	1.14.14.1	0.481
3ar4	TG1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.480
4j6c	STR	Cytochrome P450 monooxygenase	/	0.480
3rfm	CFF	Adenosine receptor A2a	/	0.480
4equ	G6I	Serine/threonine-protein kinase 10	2.7.11.1	0.479
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.478
1q5d	EPB	Epothilone C/D epoxidase	1.14	0.478
2cdu	FAD	NADH oxidase	/	0.478
2y46	MIV	Mycinamicin IV hydroxylase/epoxidase	/	0.478
3gw9	VNI	Lanosterol 14-alpha-demethylase	/	0.478
2p15	EZT	Estrogen receptor	/	0.477
2ydo	ADN	Adenosine receptor A2a	/	0.477
3a1l	2CC	Cytochrome P450	/	0.477
3p99	LNP	Lanosterol 14-alpha-demethylase	/	0.477
4jvl	EST	Estrogen sulfotransferase	2.8.2.4	0.477
4xiv	ACP	Chemotaxis protein CheA	2.7.13.3	0.477
3bfa	9OD	Odorant binding protein ASP1	/	0.476
1rti	HEF	Gag-Pol polyprotein	2.7.7.49	0.475
1xdk	REA	Retinoic acid receptor beta	/	0.475
2b36	5PP	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.475
4jlj	1NM	Deoxycytidine kinase	2.7.1.74	0.475
4nb6	444	Nuclear receptor ROR-gamma	/	0.475
3uzc	T4E	Adenosine receptor A2a	/	0.475
2agv	TG1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.474
3qfx	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.474
4fny	I3K	ALK tyrosine kinase receptor	2.7.10.1	0.474
2iod	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.473
3w5p	4OA	Vitamin D3 receptor	/	0.473
4g21	0VP	Vitamin D3 receptor A	/	0.473
1uuo	BRF	Dihydroorotate dehydrogenase (quinone), mitochondrial	1.3.5.2	0.472
2pnj	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.472
2z3u	CRR	Cytochrome P450	/	0.472
3wix	LC3	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.472
4g48	PZB	Mycocyclosin synthase	1.14.21.9	0.472
3rey	XAC	Adenosine receptor A2a	/	0.472
3qak	UKA	Adenosine receptor A2a	/	0.472
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.471
1pp9	SMA	Cytochrome b	/	0.471
4bgi	I4I	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.471
1y60	H4M	5,6,7,8-tetrahydromethanopterin hydro-lyase	4.2.1.147	0.470
1ysx	4EB	Serum albumin	/	0.470
2xk8	5R1	Serine/threonine-protein kinase Nek2	2.7.11.1	0.470
2zba	ZBA	Trichothecene 3-O-acetyltransferase	/	0.470
2zla	VDB	Vitamin D3 receptor	/	0.470
3g5h	YTT	Mycocyclosin synthase	1.14.21.9	0.470
3jyn	NDP	Quinone oxidoreductase	/	0.470
4at0	FAD	Possible succinate dehydrogenase	/	0.470
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.470
4bii	PYW	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.470
4hw3	19G	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.470
4ia7	BIV	Vitamin D3 receptor A	/	0.470
1suo	CPZ	Cytochrome P450 2B4	1.14.14.1	0.469
4aw3	MYV	Mycinamicin IV hydroxylase/epoxidase	/	0.469
5bp9	SAH	Putative methyltransferase protein	/	0.469
2aib	ERG	Beta-elicitin cinnamomin	/	0.468
3ipq	965	Oxysterols receptor LXR-alpha	/	0.468
3zze	6XP	Hepatocyte growth factor receptor	2.7.10.1	0.468
4iui	1GQ	Estrogen receptor	/	0.468
1lri	CLR	Beta-elicitin cryptogein	/	0.467
2hrc	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.467
2wpw	ACO	Orf14	/	0.467
2xvv	9DN	Serum albumin	/	0.467
2y30	SM8	Putative repressor SimReg2	/	0.467
3oez	STI	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.467
2r0p	K2C	Putative FAD-monooxygenase	/	0.466
3ar7	TG1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.466
3bxx	QUE	Dihydroflavonol 4-reductase	1.1.1.219	0.466
3dol	GWI	Pol protein	/	0.466
1fm4	DXC	Major pollen allergen Bet v 1-L	/	0.465
2hcd	BIV	Vitamin D3 receptor A	/	0.465
2x7h	PFN	Prostaglandin reductase 3	1	0.465
3t8x	T8X	T-cell surface glycoprotein CD1b	/	0.465
4apu	A2K	Progesterone receptor	/	0.465
4bfp	SWY	Tankyrase-2	2.4.2.30	0.465
4cjx	9L9	C-1-tetrahydrofolate synthase, cytoplasmic, putative	/	0.465
4dvi	2IW	Tankyrase-1	2.4.2.30	0.465
4j6d	TES	Cytochrome P450 monooxygenase	/	0.465
1fmj	RTL	Retinol dehydratase	/	0.464
1kyz	FER	Caffeic acid 3-O-methyltransferase	2.1.1.68	0.464
1vj3	TAB	Dihydrofolate reductase	1.5.1.3	0.464
2fm5	M99	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.464
3d78	NBB	Pheromone-binding protein ASP1	/	0.464
3dga	RJ1	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.464
3p6n	DSO	Camphor 5-monooxygenase	1.14.15.1	0.464
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.464
4dm6	TTB	Retinoic acid receptor beta	/	0.464
4dm8	REA	Retinoic acid receptor beta	/	0.464
4i9i	1DY	Tankyrase-1	2.4.2.30	0.464
1al8	DHP	Peroxisomal (S)-2-hydroxy-acid oxidase	1.1.3.15	0.463
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.463
2j3j	HC4	NADPH-dependent oxidoreductase 2-alkenal reductase	1.3.1.74	0.463
2q5g	1FA	Peroxisome proliferator-activated receptor delta	/	0.463
4jvm	XDI	Estrogen sulfotransferase	2.8.2.4	0.463
4jvn	YUG	Estrogen sulfotransferase	2.8.2.4	0.463
1kzj	CB3	Thymidylate synthase	/	0.462
1mcz	RMN	Benzoylformate decarboxylase	4.1.1.7	0.462
1n4h	REA	Nuclear receptor ROR-beta	/	0.462
1p44	GEQ	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.462
2dqs	TG1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.462
4la0	198	Serum albumin	/	0.462
3eml	ZMA	Adenosine receptor A2a	/	0.462
1exa	394	Retinoic acid receptor gamma	/	0.461
1fml	RTL	Retinol dehydratase	/	0.461
1hdc	CBO	3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase	1.1.1.53	0.461
1so2	666	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.461
2fzi	DH3	Dihydrofolate reductase	1.5.1.3	0.461
2rl5	2RL	Vascular endothelial growth factor receptor 2	2.7.10.1	0.461
3cse	N22	Uncharacterized protein	/	0.461
3dle	GFA	Gag-Pol polyprotein	2.7.7.49	0.461
3inv	C50	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.461
3lfc	Z86	Mitogen-activated protein kinase 14	/	0.461
3zia	ADP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.461
4bfw	ZVW	Pantothenate kinase	2.7.1.33	0.461
4ict	1ED	Mycocyclosin synthase	1.14.21.9	0.461
4j6b	PLO	Cytochrome P450 monooxygenase	/	0.461
4rlh	0WE	Enoyl-[acyl-carrier-protein] reductase [NADH]	/	0.461
4y8w	STR	Steroid 21-hydroxylase	/	0.461
1cjc	FAD	NADPH:adrenodoxin oxidoreductase, mitochondrial	1.18.1.6	0.460
1nq7	ARL	Nuclear receptor ROR-beta	/	0.460
1osv	CHC	Bile acid receptor	/	0.460
2c7x	NRB	Cytochrome P450 monooxygenase PikC	/	0.460
2d29	FAD	Acyl-CoA dehydrogenase	/	0.460
2uxo	TAC	HTH-type transcriptional regulator TtgR	/	0.460
3ar6	TG1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.460
3irx	UDR	Gag-Pol polyprotein	2.7.7.49	0.460
3lu8	IQX	Serum albumin	/	0.460
3new	3NE	Mitogen-activated protein kinase 14	/	0.460
3w1w	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.460
4iw8	KN3	Estrogen receptor	/	0.460
1qiq	ACC	Isopenicillin N synthase	1.21.3.1	0.459
1x8l	OXR	Retinol dehydratase	/	0.459
2e99	B08	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.459
2fzh	DH1	Dihydrofolate reductase	1.5.1.3	0.459
3vtd	TKD	Vitamin D3 receptor	/	0.459
3w5r	LOA	Vitamin D3 receptor	/	0.459
4g3j	VNT	Lanosterol 14-alpha-demethylase	/	0.459
4nky	3QZ	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.459
4pd6	URI	Nucleoside permease	/	0.459
5kf8	ACO	Predicted acetyltransferase	/	0.459
1cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.458
1ek2	CDU	Bifunctional epoxide hydrolase 2	/	0.458
1y2k	7DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.458
2uxh	QUE	HTH-type transcriptional regulator TtgR	/	0.458
2ydv	NEC	Adenosine receptor A2a	/	0.458
4bkj	STI	Epithelial discoidin domain-containing receptor 1	2.7.10.1	0.458
1bk0	ACV	Isopenicillin N synthase	1.21.3.1	0.457
2fhj	MFN	Formylmethanofuran--tetrahydromethanopterin formyltransferase	2.3.1.101	0.457
2pnu	ENM	Androgen receptor	/	0.457
2pr2	DG1	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.457
3e5a	VX6	Aurora kinase A	2.7.11.1	0.457
3fco	IIG	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.457
3gmd	2M3	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.457
3gyt	DL4	Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily	/	0.457
4gue	QCT	Ribosomal protein S6 kinase alpha-3	2.7.11.1	0.457
4ivy	1GT	Estrogen receptor	/	0.457
4n4v	2GY	Tankyrase-1	2.4.2.30	0.457
4o70	1QK	Bromodomain-containing protein 4	/	0.457
4qe6	JN3	Bile acid receptor	/	0.457
5ab7	MLC	Nonspecific lipid-transfer protein, putative	/	0.457
1rf9	DBR	Camphor 5-monooxygenase	1.14.15.1	0.456
1soj	IBM	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.456
2hw2	RFP	Rifampin ADP-ribosyl transferase	/	0.456
3kyt	HC2	Nuclear receptor ROR-gamma	/	0.456
3p6o	ETG	Camphor 5-monooxygenase	1.14.15.1	0.456
4bb5	HD2	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.456
4kwi	1TJ	Reductase homolog	/	0.456
5kf9	ACO	Predicted acetyltransferase	/	0.456
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.455
1dyr	TOP	Dihydrofolate reductase	1.5.1.3	0.455
1hk3	T44	Serum albumin	/	0.455
1tbb	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.455
1wsv	THH	Aminomethyltransferase, mitochondrial	/	0.455
1y2d	4DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.455
2chw	039	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.455
3is9	AC7	Gag-Pol polyprotein	2.7.7.49	0.455
3nr4	PYV	Abscisic acid receptor PYL2	/	0.455
3qm4	PN0	Cytochrome P450 2D6	/	0.455
3zoi	M2W	Isopenicillin N synthase	1.21.3.1	0.455
4iq7	1G9	Mycocyclosin synthase	1.14.21.9	0.455
2jc6	QPP	Calcium/calmodulin-dependent protein kinase type 1D	2.7.11.17	0.454
2w4q	CBW	Prostaglandin reductase 2	1.3.1.48	0.454
3eel	53T	Uncharacterized protein	/	0.454
3fzn	D7K	Benzoylformate decarboxylase	4.1.1.7	0.454
3stw	2TD	Methylketone synthase I	/	0.454
4e6a	0O9	Mitogen-activated protein kinase 14	/	0.454
4jbt	ASD	Cytochrome P450 monooxygenase	/	0.454
4wa9	AXI	Tyrosine-protein kinase ABL1	2.7.10.2	0.454
1d3g	BRE	Dihydroorotate dehydrogenase (quinone), mitochondrial	1.3.5.2	0.453
1fcx	184	Retinoic acid receptor gamma	/	0.453
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.453
1klk	PMD	Dihydrofolate reductase	1.5.1.3	0.453
1og5	SWF	Cytochrome P450 2C9	/	0.453
1ot7	IU5	Bile acid receptor	/	0.453
1tsd	F89	Thymidylate synthase	/	0.453
1zhz	ERG	Oxysterol-binding protein homolog 4	/	0.453
2rkv	ZBA	Trichothecene 3-O-acetyltransferase	/	0.453
3clx	X22	E3 ubiquitin-protein ligase XIAP	6.3.2	0.453
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.453
3hub	469	Mitogen-activated protein kinase 14	/	0.453
3iw8	HIZ	Mitogen-activated protein kinase 14	/	0.453
3stx	BKA	Methylketone synthase I	/	0.453
4inb	1F6	Gag protein	/	0.453
4ipw	1G7	Mycocyclosin synthase	1.14.21.9	0.453
4mvh	2F5	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.453
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.453
3uza	T4G	Adenosine receptor A2a	/	0.453
1fdu	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.452
1ia4	TQ6	Dihydrofolate reductase	1.5.1.3	0.452
1prc	UQ1	Reaction center protein L chain	/	0.452
1qjf	ACS	Isopenicillin N synthase	1.21.3.1	0.452
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.452
1re9	DSO	Camphor 5-monooxygenase	1.14.15.1	0.452
2jfz	003	Glutamate racemase	/	0.452
2wpx	ACO	Orf14	/	0.452
3ada	NAD	Subunit alpha of sarocosine oxidase	/	0.452
3b9l	AZZ	Serum albumin	/	0.452
3bfb	9OD	Pheromone-binding protein ASP1	/	0.452
3fko	FKO	Mitogen-activated protein kinase 14	/	0.452
3gbk	2PQ	Peroxisome proliferator-activated receptor gamma	/	0.452
3i68	J4Z	Dihydroorotate dehydrogenase (quinone), mitochondrial	1.3.5.2	0.452
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.452
4el9	AFE	Ribosomal protein S6 kinase alpha-3	2.7.11.1	0.452
4g1z	0VP	Vitamin D3 receptor A	/	0.452
4ia1	BIV	Vitamin D3 receptor A	/	0.452
4nkv	AER	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.452
5uvi	ZMA	Adenosine receptor A2a	/	0.452
1dgf	NDP	Catalase	1.11.1.6	0.451
1m9m	6NI	Nitric oxide synthase, endothelial	1.14.13.39	0.451
1o6r	R19	Squalene--hopene cyclase	4.2.1.129	0.451
2ij7	TPF	Mycocyclosin synthase	1.14.21.9	0.451
3bqd	DAY	Glucocorticoid receptor	/	0.451
3gyu	DL7	Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily	/	0.451
3tyl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.451
4a83	DXC	Major pollen allergen Bet v 1-A	/	0.451
4bbx	LKF	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.451
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.451
4hw2	19H	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.451
5g53	NEC	Adenosine receptor A2a	/	0.451
5k2b	ZMA	Adenosine receptor A2a	/	0.451
1n83	CLR	Nuclear receptor ROR-alpha	/	0.450
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.450
1y5r	C0R	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.450
2b0m	201	Dihydroorotate dehydrogenase (quinone), mitochondrial	1.3.5.2	0.450
2gpu	OHT	Estrogen-related receptor gamma	/	0.450
2hwr	DRD	Peroxisome proliferator-activated receptor gamma	/	0.450
2qo4	CHD	Fatty acid-binding protein 10-A, liver basic	/	0.450
2uxp	CLM	HTH-type transcriptional regulator TtgR	/	0.450
3fnu	006	HAP protein	/	0.450
3gph	OID	Cytochrome P450 2E1	1.14.13	0.450
3ibd	CPZ	Cytochrome P450 2B6	1.14.13	0.450
3qpp	PFW	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.450
3sa2	7DR	Dihydrofolate reductase	/	0.450
3td8	D2R	Dihydrofolate reductase	1.5.1.3	0.450
3v94	WYQ	Phosphodiesterase	/	0.450
4ddl	0JQ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.450
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.450
4xoq	F42	Coenzyme F420:L-glutamate ligase	/	0.450
5bn3	ADP	V-type ATP synthase alpha chain	/	0.450
5bn3	ADP	NEQ263	/	0.450
5c93	ACP	Two-component system histidine protein kinase	/	0.450
4uhr	NGI	Adenosine receptor A2a	/	0.450
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.449
1ezf	IN0	Squalene synthase	2.5.1.21	0.449
1i7i	AZ2	Peroxisome proliferator-activated receptor gamma	/	0.449
1s19	MC9	Vitamin D3 receptor	/	0.449
2bnp	MST	Reaction center protein L chain	/	0.449
2ivi	ACW	Isopenicillin N synthase	1.21.3.1	0.449
2mm3	CHO	Gastrotropin	/	0.449
2o7p	NAP	Riboflavin biosynthesis protein RibD	/	0.449
2ovy	PFJ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
2xkc	4VQ	Serine/threonine-protein kinase Nek2	2.7.11.1	0.449
3aba	FLI	Cytochrome P450	/	0.449
3ch6	311	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.449
3clb	TMQ	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.449
3ol5	SAW	Camphor 5-monooxygenase	1.14.15.1	0.449
3ozd	4CT	S-methyl-5'-thioadenosine phosphorylase	/	0.449
3qpn	PFK	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
3sgv	2BJ	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.449
3v4e	COA	Putative acetyltransferase SACOL2570	2.3.1	0.449
3vt4	5YI	Vitamin D3 receptor	/	0.449
4ajw	VWN	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	2.7.1.153	0.449
4dsc	A8S	Abscisic acid receptor PYL3	/	0.449
4jx1	CAM	Camphor 5-monooxygenase	1.14.15.1	0.449
4muw	2F4	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
5bvw	1N1	Epithelial discoidin domain-containing receptor 1	2.7.10.1	0.449
1kyo	SMA	Cytochrome b	/	0.448
1ly4	COQ	Dihydrofolate reductase	1.5.1.3	0.448
1tvr	TB9	Gag-Pol polyprotein	2.7.7.49	0.448
1uy7	PU4	Heat shock protein HSP 90-alpha	/	0.448
1xp6	AIU	Estrogen receptor	/	0.448
1zg3	2HI	Isoflavone 4'-O-methyltransferase	/	0.448
2lbd	REA	Retinoic acid receptor gamma	/	0.448
2wey	EV1	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.448
3c3x	NAP	Eugenol synthase 1	1.1.1.318	0.448
3i1f	GCP	Translation initiation factor 2 subunit gamma	/	0.448
3m8c	EQU	Steroid Delta-isomerase	5.3.3.1	0.448
3mdm	FJZ	Cholesterol 24-hydroxylase	/	0.448
3n3z	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.448
3o9l	LPN	Renin	3.4.23.15	0.448
3opd	HIE	Heat shock protein 83	/	0.448
3sh0	SAX	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.448
3th8	TH9	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.448
3um6	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.448
3up0	D7S	aceDAF-12	/	0.448
3wgw	T2B	Proliferating cell nuclear antigen	/	0.448
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.448
4gev	CB3	Thymidylate synthase	/	0.448
1aqb	RTL	Retinol-binding protein 4	/	0.447
1dis	BDM	Dihydrofolate reductase	1.5.1.3	0.447
1fp1	HCC	Isoliquiritigenin 2'-O-methyltransferase	/	0.447
1kk4	ACO	Streptogramin A acetyltransferase	2.3.1	0.447
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.447
1ppj	ANY	Cytochrome b	/	0.447
1qip	GNB	Lactoylglutathione lyase	4.4.1.5	0.447
2a4z	BYM	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.447
2azy	CHD	Phospholipase A2, major isoenzyme	3.1.1.4	0.447
2hc4	VDX	Vitamin D3 receptor A	/	0.447
2pl0	STI	Tyrosine-protein kinase Lck	2.7.10.2	0.447
2vcm	M11	Isopenicillin N synthase	1.21.3.1	0.447
3cbs	R12	Cellular retinoic acid-binding protein 2	/	0.447
3i0r	RT3	Gag-Pol polyprotein	2.7.7.49	0.447
3kjs	DQ1	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.447
3vt9	YI4	Vitamin D3 receptor	/	0.447
4dch	4DC	Glucokinase	2.7.1.2	0.447
4egn	TWO	Cytochrome P450	/	0.447
4f9m	FCM	Peroxisome proliferator-activated receptor gamma	/	0.447
4g1n	NZT	Pyruvate kinase PKM	2.7.1.40	0.447
4jv6	18F	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	/	0.447
4ktl	1CQ	Cytochrome P450	/	0.447
4nmb	FAD	Bifunctional protein PutA	/	0.447
1eio	GCH	Gastrotropin	/	0.446
1hb3	SCV	Isopenicillin N synthase	1.21.3.1	0.446
1kl2	FON	Serine hydroxymethyltransferase	/	0.446
1m9k	7NI	Nitric oxide synthase, endothelial	1.14.13.39	0.446
1pqc	444	Oxysterols receptor LXR-beta	/	0.446
1upw	444	Oxysterols receptor LXR-beta	/	0.446
1v7a	FRC	Adenosine deaminase	3.5.4.4	0.446
1x2h	LPA	Lipoate-protein ligase A	6.3.1.20	0.446
1y2c	3DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.446
2cl5	BIE	Catechol O-methyltransferase	2.1.1.6	0.446
2dw4	FAD	Lysine-specific histone demethylase 1A	1	0.446
2qd3	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.446
2zl9	VDA	Vitamin D3 receptor	/	0.446
2znn	S44	Peroxisome proliferator-activated receptor alpha	/	0.446
3huc	G97	Mitogen-activated protein kinase 14	/	0.446
3iel	U5P	Ribonuclease TTHA0252	3.1	0.446
3mnr	SD1	Heat shock protein HSP 90-alpha	/	0.446
3qlx	QLR	Uncharacterized protein	/	0.446
3w5q	3KL	Vitamin D3 receptor	/	0.446
4bge	PYW	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.446
4gh6	LUO	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.446
4h96	14Q	Dihydrofolate reductase	1.5.1.3	0.446
4o76	1M3	Bromodomain-containing protein 4	/	0.446
4rw4	494	Gag-Pol polyprotein	2.7.7.49	0.446
4zm6	ACO	N-acetyl-beta-D glucosaminidase	/	0.446
1cqp	803	Integrin alpha-L	/	0.445
1hb1	OCV	Isopenicillin N synthase	1.21.3.1	0.445
1hni	AAA	Gag-Pol polyprotein	2.7.7.49	0.445
1ml6	GBX	Glutathione S-transferase A2	2.5.1.18	0.445
1nbm	ADP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.445
2e9c	B75	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.445
2gzl	2AA	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	4.6.1.12	0.445
2i4z	DRH	Peroxisome proliferator-activated receptor gamma	/	0.445
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.445
2qk8	MTX	Dihydrofolate reductase	/	0.445
2znq	401	Peroxisome proliferator-activated receptor delta	/	0.445
3c0i	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.445
3cv9	VDX	Vitamin D3 dihydroxylase	/	0.445
3ds6	A17	Mitogen-activated protein kinase 14	/	0.445
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.445
3nlw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.445
3q0g	BCO	Probable enoyl-CoA hydratase echA8	4.2.1.17	0.445
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.445
3u8h	BHP	Phospholipase A2, membrane associated	/	0.445
4c68	NHW	Glycylpeptide N-tetradecanoyltransferase	/	0.445
4ge7	0K5	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.445
4ia3	BIV	Vitamin D3 receptor A	/	0.445
1daj	MOT	Dihydrofolate reductase	1.5.1.3	0.444
1ivr	CBA	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.444
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.444
1khr	COA	Streptogramin A acetyltransferase	2.3.1	0.444
1q0r	AKT	Aclacinomycin methylesterase RdmC	3.1.1.95	0.444
1thn	ADP	Anti-sigma F factor	/	0.444
2ic3	HBY	Gag-Pol polyprotein	2.7.7.49	0.444
2jbl	SMA	Reaction center protein L chain	/	0.444
2vcw	ZZA	Hematopoietic prostaglandin D synthase	/	0.444
2x23	TCU	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.444
2xc3	RT8	Steroid C26-monooxygenase	1.14.13.141	0.444
2zd1	T27	Gag-Pol polyprotein	2.7.7.49	0.444
2zlc	VDX	Vitamin D3 receptor	/	0.444
3cs8	BRL	Peroxisome proliferator-activated receptor gamma	/	0.444
3cyz	9OD	Pheromone-binding protein ASP1	/	0.444
3d3e	D3E	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.444
3d74	NBB	Pheromone-binding protein ASP1	/	0.444
3dxj	NE6	DNA-directed RNA polymerase subunit beta	/	0.444
3dxj	NE6	DNA-directed RNA polymerase subunit beta'	/	0.444
3h3t	16H	Collagen type IV alpha-3-binding protein	/	0.444
3lfm	3DT	Alpha-ketoglutarate-dependent dioxygenase FTO	/	0.444
3nj0	PYV	Abscisic acid receptor PYL2	/	0.444
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.444
4a81	DXC	Major pollen allergen Bet v 1-A	/	0.444
4a9h	TVP	Bromodomain-containing protein 2	/	0.444
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.444
4boe	CLR	Japanin	/	0.444
4dvq	1CA	Cytochrome P450 11B2, mitochondrial	1.14.15.4	0.444
4gqe	H4B	Nitric oxide synthase, brain	1.14.13.39	0.444
4hyf	1AK	Tankyrase-2	2.4.2.30	0.444
4iae	1DX	Alr2278 protein	/	0.444
4jlk	1NO	Deoxycytidine kinase	2.7.1.74	0.444
4ri1	ACO	UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	2.3.1.202	0.444
4ruo	BIV	Vitamin D3 receptor A	/	0.444
5kf2	ACO	Predicted acetyltransferase	/	0.444
1lwl	DSO	Camphor 5-monooxygenase	1.14.15.1	0.443
1nhz	486	Glucocorticoid receptor	/	0.443
1udt	VIA	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.443
1xds	DRA	Aclacinomycin 10-hydroxylase RdmB	4.1.1	0.443
1xu9	CPS	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.443
2ewp	TXF	Estrogen-related receptor gamma	/	0.443
2gvc	FAD	Thiol-specific monooxygenase	1.14.13	0.443
2iog	IOG	Estrogen receptor	/	0.443
2jed	LG8	Protein kinase C theta type	2.7.11.13	0.443
2r6j	NDP	Eugenol synthase 1	1.1.1.318	0.443
3cd2	MTX	Dihydrofolate reductase	1.5.1.3	0.443
3jsu	KA5	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.443
3sl6	JN8	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.443
3tgu	WF3	Cytochrome b	/	0.443
3uzw	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.443
4bcm	T7Z	Cyclin-dependent kinase 2	2.7.11.22	0.443
4fhh	0U3	Vitamin D3 receptor A	/	0.443
4hle	17V	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.443
4i8v	BHF	Cytochrome P450 1A1	1.14.14.1	0.443
4mxe	ACO	N-acetyltransferase ESCO1	2.3.1	0.443
4p6w	MOF	Glucocorticoid receptor	/	0.443
4v12	POG	MaoC like domain protein	/	0.443
5hs1	VOR	Lanosterol 14-alpha demethylase	/	0.443
5iu8	6DZ	Adenosine receptor A2a	/	0.443
1db1	VDX	Vitamin D3 receptor	/	0.442
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.442
1kkq	471	Peroxisome proliferator-activated receptor alpha	/	0.442
1o6q	R17	Squalene--hopene cyclase	4.2.1.129	0.442
1rdt	570	Peroxisome proliferator-activated receptor gamma	/	0.442
1xdd	AAY	Integrin alpha-L	/	0.442
1ykd	CMP	Adenylate cyclase	/	0.442
2ops	HBQ	Gag-Pol polyprotein	2.7.7.49	0.442
2ph5	NAD	Homospermidine synthase	/	0.442
2vn0	TDZ	Cytochrome P450 2C8	/	0.442
3d76	NBB	Pheromone-binding protein ASP1	/	0.442
3fl4	FL4	Mitogen-activated protein kinase 14	/	0.442
3ml8	ML8	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.442
3nx4	NAP	Putative oxidoreductase	/	0.442
3tm5	SFG	Uncharacterized protein	/	0.442
3uic	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH]	/	0.442
3vt5	YI2	Vitamin D3 receptor	/	0.442
4a32	2CD	Glycylpeptide N-tetradecanoyltransferase	/	0.442
4bfu	ZVU	Pantothenate kinase	2.7.1.33	0.442
4do3	0LA	Fatty-acid amide hydrolase 1	3.5.1.99	0.442
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.442
4ips	1G4	Mycocyclosin synthase	1.14.21.9	0.442
4li7	1XP	Tankyrase-1	2.4.2.30	0.442
4nie	NBH	Nuclear receptor ROR-gamma	/	0.442
4pkl	1GH	Uncharacterized protein	/	0.442
4uyf	73B	Bromodomain-containing protein 2	/	0.442
5hbr	COA	Acyl-CoA synthetase (NDP forming)	/	0.442
3pwh	ZMA	Adenosine receptor A2a	/	0.442
1dna	CB3	Thymidylate synthase	/	0.441
1mr9	ACO	Streptogramin A acetyltransferase	2.3.1	0.441
1q0z	AKA	Aclacinomycin methylesterase RdmC	3.1.1.95	0.441
1t0i	FMN	NAD(P)H-dependent FMN reductase LOT6	/	0.441
2aqk	NAI	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.441
2azz	TCH	Phospholipase A2, major isoenzyme	3.1.1.4	0.441
2g2h	P16	Tyrosine-protein kinase ABL1	2.7.10.2	0.441
2om9	AJA	Peroxisome proliferator-activated receptor gamma	/	0.441
2qg2	A91	Heat shock protein HSP 90-alpha	/	0.441
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.441
2wle	COA	Polysialic acid O-acetyltransferase	/	0.441
2yek	EAM	Bromodomain-containing protein 2	/	0.441
3d3p	20A	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.441
3eta	351	Insulin receptor	2.7.10.1	0.441
3ffi	3OB	Gag-Pol polyprotein	2.7.7.49	0.441
3hcr	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.441
3hng	8ST	Vascular endothelial growth factor receptor 1	2.7.10.1	0.441
3lan	KBT	Gag-Pol polyprotein	2.7.7.49	0.441
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.441
3t2k	FAD	Sulfide-quinone reductase	/	0.441
3up3	XCA	aceDAF-12	/	0.441
3vrw	YS5	Vitamin D3 receptor	/	0.441
4a2j	AS0	Progesterone receptor	/	0.441
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.441
4ubu	COA	Steroid 3-ketoacyl-CoA thiolase	/	0.441
5hwq	CAA	Hydroxymethylglutaryl-CoA synthase	/	0.441
1e1n	FAD	NADPH:adrenodoxin oxidoreductase, mitochondrial	1.18.1.6	0.440
1i59	ANP	Chemotaxis protein CheA	2.7.13.3	0.440
1kqw	RTL	Cellular retinol-binding protein type II	/	0.440
1l0l	FMX	Cytochrome b	/	0.440
1m13	HYF	Nuclear receptor subfamily 1 group I member 2	/	0.440
1p91	SAM	23S rRNA (guanine(745)-N(1))-methyltransferase	/	0.440
1y0s	331	Peroxisome proliferator-activated receptor delta	/	0.440
2bkt	RPF	Renin	3.4.23.15	0.440
2gtk	208	Peroxisome proliferator-activated receptor gamma	/	0.440
2h94	FAD	Lysine-specific histone demethylase 1A	1	0.440
2nnh	REA	Cytochrome P450 2C8	/	0.440
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.440
2yke	YKE	Heat shock protein HSP 90-alpha	/	0.440
3c1t	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.440
3eek	53S	Uncharacterized protein	/	0.440
3h3s	H15	Collagen type IV alpha-3-binding protein	/	0.440
3inw	JZB	Heat shock protein HSP 90-alpha	/	0.440
3nfa	CBJ	Gag-Pol polyprotein	/	0.440
3nga	3NG	Casein kinase II subunit alpha	2.7.11.1	0.440
3tmz	06X	Cytochrome P450 2B4	1.14.14.1	0.440
4bqp	VMY	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.440
4cdm	FO1	Deoxyribodipyrimidine photolyase	/	0.440
4h4o	506	Gag-Pol polyprotein	2.7.7.49	0.440
4h4u	NDP	Biphenyl dioxygenase ferredoxin reductase subunit	/	0.440
4ixd	1HV	Integrin alpha-L	/	0.440
4jqh	1MF	Alr2278 protein	/	0.440
4kne	1CY	Dihydrofolate reductase	1.5.1.3	0.440
4lb2	DM5	Serum albumin	/	0.440
4m52	FAD	Dihydrolipoyl dehydrogenase	1.8.1.4	0.440
5kgh	ACO	Predicted acetyltransferase	/	0.440