sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 1.000 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.641 | |
| 4wrk | DUP | DUTPase | / | 0.580 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.530 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.518 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.518 | |
| 2oke | DUP | DUTP pyrophosphatase | / | 0.513 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.509 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.503 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.503 | |
| 1snf | UMP | Deoxyuridine 5'-triphosphate nucleotidohydrolase | 3.6.1.23 | 0.500 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.500 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.495 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.493 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.489 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.488 | |
| 1vyq | DUX | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.486 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.486 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.486 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.483 | |
| 2q9c | GNP | Signal recognition particle receptor FtsY | / | 0.482 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.482 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.481 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.481 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.479 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.479 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.479 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.479 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.475 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.474 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.473 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 1ual | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.472 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.472 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.472 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.471 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.471 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.470 | |
| 4a5s | N7F | Dipeptidyl peptidase 4 | / | 0.470 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.469 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.469 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.469 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.469 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.468 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.468 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.468 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.468 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.468 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.468 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.467 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.467 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.467 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.467 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.467 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.466 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.466 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.466 | |
| 3d64 | NAD | Adenosylhomocysteinase | / | 0.465 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.464 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.464 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.464 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.464 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.464 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.464 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.464 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.463 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.463 | |
| 2nr4 | FMN | Conserved protein | / | 0.463 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.463 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.462 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.462 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.462 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.462 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.462 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.461 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.461 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.461 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.461 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.461 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.461 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.460 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.460 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.460 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.460 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.459 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.459 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.459 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.459 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.459 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.459 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.459 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.458 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.458 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.458 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.458 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.457 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.457 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.457 | |
| 2ol0 | DUD | DUTP pyrophosphatase | / | 0.457 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.457 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3qvi | K95 | HAP protein | / | 0.457 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.457 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.457 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.457 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.456 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.456 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.456 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.456 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.456 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.456 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.456 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.456 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.456 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.455 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.455 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.455 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.455 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.455 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.454 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.454 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 3eku | CY9 | Actin-5C | / | 0.454 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3r96 | ACO | MccE protein | / | 0.454 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.454 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.454 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.454 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.453 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.452 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.452 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.452 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.452 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.451 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.451 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.451 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.450 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.450 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.450 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.450 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.450 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.450 | |
| 4lut | DCS | Alanine racemase | / | 0.450 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.449 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.449 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.449 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.449 | |
| 2r8p | T6F | Transketolase 1 | / | 0.449 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.449 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.448 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.448 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.448 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.448 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.448 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.448 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.448 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.447 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.447 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.447 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.447 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.447 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4b5d | SW4 | Achbp | / | 0.447 | |
| 4jic | FMN | GTN Reductase | / | 0.447 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.447 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.447 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.447 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.446 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.446 | |
| 2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.446 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.446 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.446 | |
| 3eks | CY9 | Actin-5C | / | 0.446 | |
| 3g0d | XIH | Dipeptidyl peptidase 4 | / | 0.446 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.446 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.446 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.446 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.446 | |
| 4uoc | NCN | CinA-like protein | / | 0.446 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.446 | |
| 1c7o | PPG | Hemolysin | / | 0.445 | |
| 1iqg | XME | Coagulation factor X | 3.4.21.6 | 0.445 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.445 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3fsu | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.445 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.445 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.445 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.445 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.445 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.444 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.444 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.444 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.444 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.444 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.444 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.444 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.444 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3rfa | SAM | Dual-specificity RNA methyltransferase RlmN | / | 0.444 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.444 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.444 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.444 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.443 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.443 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.443 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.443 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3bnk | FMN | Flavoredoxin | / | 0.443 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.443 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.443 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.443 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.442 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.442 | |
| 2ejz | SAH | Diphthine synthase | / | 0.442 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.442 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.442 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.442 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.442 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.442 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.442 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.442 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.442 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.441 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.441 | |
| 2xvq | 9DS | Serum albumin | / | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.441 | |
| 4c4o | NAD | SADH | / | 0.441 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.441 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.441 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.441 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.441 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.441 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.440 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.440 | |
| 2po3 | T4K | 4-dehydrase | / | 0.440 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.440 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.440 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.440 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.440 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.440 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.440 | |
| 3l5d | BDV | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.440 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 |