sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 1.000 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.649 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.641 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.595 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.548 | |
| 3ghh | 2NF | CD38 molecule | / | 0.522 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.514 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.511 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.498 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.497 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.497 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.496 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.490 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.489 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.489 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.484 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.483 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.482 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.482 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.481 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.478 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.477 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.476 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.476 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.475 | |
| 1rxj | BNI | Streptavidin | / | 0.474 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.474 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.474 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.473 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.473 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.473 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.473 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.472 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.472 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.471 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3v2u | ATP | Protein GAL3 | / | 0.470 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.469 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.467 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.467 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.466 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.466 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.466 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.465 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.465 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.465 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.465 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.464 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.464 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.464 | |
| 4rel | KMP | Glycosyltransferase | / | 0.464 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.464 | |
| 5bn3 | ADP | NEQ263 | / | 0.464 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.463 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.462 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.462 | |
| 3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.462 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.461 | |
| 3irh | DTP | HD domain protein | / | 0.461 | |
| 3p5s | AVU | CD38 molecule | / | 0.461 | |
| 5doz | NDP | JamJ | / | 0.461 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.460 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.460 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.460 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.460 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.459 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.459 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.459 | |
| 2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.459 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.458 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.458 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.458 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.457 | |
| 2ejz | SAH | Diphthine synthase | / | 0.457 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.457 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.457 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.457 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.457 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.457 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1wkh | PPE | [LysW]-aminoadipate semialdehyde transaminase | / | 0.456 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.456 | |
| 2v5u | FMN | Flavodoxin | / | 0.456 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3c6p | 2S3 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.456 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.456 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.455 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3c6n | 2S8 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.455 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.455 | |
| 3kn0 | 3TO | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 1vp5 | NAP | Oxidoreductase, aldo/keto reductase family | / | 0.454 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.454 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.454 | |
| 2oat | PFM | Ornithine aminotransferase, mitochondrial | 2.6.1.13 | 0.454 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.454 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.453 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.453 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.453 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.453 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.453 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.453 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.452 | |
| 2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.452 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.452 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.452 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.452 | |
| 1c7o | PPG | Hemolysin | / | 0.451 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.451 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.451 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.451 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.450 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.450 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.450 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.450 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.449 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.449 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.449 | |
| 1wua | AP8 | Actin, alpha skeletal muscle | / | 0.449 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.449 | |
| 2gms | P0P | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.449 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.449 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.449 | |
| 4yfy | 0FX | VioF | / | 0.449 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2xeg | CI9 | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.448 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.448 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.448 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.448 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.448 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.448 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.447 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.447 | |
| 1ppj | ANY | Cytochrome b | / | 0.447 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.447 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.447 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1w19 | T2P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.446 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.446 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.446 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.446 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4cb6 | 29R | Polymerase basic protein 2 | / | 0.446 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.446 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.446 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.446 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.446 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.446 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.445 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.445 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.445 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.445 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.445 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.444 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.444 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.444 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4g1c | CNA | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.444 | |
| 4hcy | 0YN | Transketolase | / | 0.444 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.443 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.443 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 1swg | BTN | Streptavidin | / | 0.443 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2yay | DUP | DUTPase | / | 0.443 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.443 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.443 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.443 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 3ufy | NPX | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.443 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.443 | |
| 4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 1el4 | CTZ | Obelin | / | 0.442 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.442 | |
| 1swt | BTN | Streptavidin | / | 0.442 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.442 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.442 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.442 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.442 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3eks | CY9 | Actin-5C | / | 0.442 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.442 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.441 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.441 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 1zdw | FLV | Prenyltransferase | / | 0.441 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.441 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.441 | |
| 2b99 | RDL | Riboflavin synthase | 2.5.1.9 | 0.441 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.441 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3ele | PLP | Aminotransferase | / | 0.441 | |
| 3i9k | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | 3.2.2.6 | 0.441 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.441 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 4j7g | TRH | PCZA361.3 | / | 0.441 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.440 | |
| 2qjp | ANJ | Cytochrome b | / | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.440 | |
| 3gf4 | U5P | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.440 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.440 |