sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 1.000 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.642 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.639 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.513 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.509 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.508 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.503 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.503 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.502 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.500 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.498 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.498 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.497 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.496 | |
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.495 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.491 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.487 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.485 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.484 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.484 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.483 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.483 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.482 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.481 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.480 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.478 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.478 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.478 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.477 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.477 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.477 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.476 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.476 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.476 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.476 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.474 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.473 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.473 | |
| 4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.473 | |
| 1c7o | PPG | Hemolysin | / | 0.471 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.471 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.471 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.470 | |
| 2idv | M7G | Eukaryotic translation initiation factor 4E-1 | / | 0.470 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.470 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.470 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.469 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.468 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.468 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.468 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.468 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.466 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.466 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.466 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.466 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.465 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.465 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.465 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.464 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.463 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.463 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.463 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.463 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.462 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.461 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.461 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.461 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.461 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.460 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.460 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.459 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.459 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.459 | |
| 2ylx | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.459 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.459 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.459 | |
| 3v2u | ATP | Protein GAL3 | / | 0.459 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.459 | |
| 4dyb | 0MH | Nucleoprotein | / | 0.459 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.459 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.459 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.459 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.459 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.458 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.458 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.458 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.458 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.458 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.457 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.457 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.457 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.457 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.457 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 3klb | FMN | Uncharacterized protein | / | 0.456 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.456 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
| 4nv1 | TYD | Formyl transferase | / | 0.456 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3zgz | 84T | Leucine--tRNA ligase | / | 0.455 | |
| 4dya | 0MF | Nucleoprotein | / | 0.455 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.455 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.455 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.454 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.454 | |
| 3q1k | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.454 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.454 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.454 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.454 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.454 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.454 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.454 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.453 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.453 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.453 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.453 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.453 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.452 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.452 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.452 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.452 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.452 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.451 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.451 | |
| 2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.451 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.451 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.451 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.450 | |
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.450 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3i12 | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.450 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.450 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.450 | |
| 5doz | NDP | JamJ | / | 0.450 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.449 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.449 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 4qly | FMN | Enone reductase CLA-ER | / | 0.449 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.449 | |
| 1ecb | 5GP | Amidophosphoribosyltransferase | / | 0.448 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.448 | |
| 1pgt | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.448 | |
| 2r8o | T5X | Transketolase 1 | / | 0.448 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.448 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.448 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.447 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.447 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.447 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.447 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.447 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 4wrk | DUP | DUTPase | / | 0.447 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.447 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.446 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.446 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.446 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.446 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.446 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.446 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.445 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2v8p | CDP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 2vet | UMP | Thymidylate synthase | / | 0.445 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.445 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.445 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.445 | |
| 4a7z | AY9 | Aldos-2-ulose dehydratase | / | 0.445 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.445 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.445 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.444 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.444 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.444 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.444 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.444 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.444 | |
| 3frk | TQP | QdtB | / | 0.444 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.444 | |
| 3lcj | COA | Phosphopantetheine adenylyltransferase | / | 0.444 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.444 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.444 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4lut | DCS | Alanine racemase | / | 0.444 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 4xsv | CTP | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.443 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.443 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2x3j | ATP | AcsD | / | 0.443 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.443 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.443 | |
| 3fvu | IAC | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.443 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.443 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.443 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.443 | |
| 4to5 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 4zwe | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.443 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.443 | |
| 1dp2 | LPB | Thiosulfate sulfurtransferase | / | 0.442 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.442 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.442 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.442 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.442 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.442 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.442 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.442 | |
| 4tm4 | FDA | KtzI | / | 0.442 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.441 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.441 | |
| 1qrt | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.441 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.441 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.441 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.441 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.441 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4um1 | 09P | Acetylcholine-binding protein | / | 0.441 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.440 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 1og1 | TAD | T-cell ecto-ADP-ribosyltransferase 2 | / | 0.440 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.440 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.440 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.440 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.440 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.440 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.440 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 |