sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 | 1.000 | |
| 2vj7 | VG6 | Beta-secretase 1 | 3.4.23.46 | 0.718 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.710 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.709 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.690 | |
| 2viz | VG4 | Beta-secretase 1 | 3.4.23.46 | 0.679 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.678 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.670 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.666 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.662 | |
| 2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 | 0.662 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.661 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.638 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.637 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.634 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.624 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.613 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.610 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.608 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.606 | |
| 2vnn | CM7 | Beta-secretase 1 | 3.4.23.46 | 0.602 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.602 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.600 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.597 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.595 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.588 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.587 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.585 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.582 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.582 | |
| 2vj9 | VG7 | Beta-secretase 1 | 3.4.23.46 | 0.581 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.577 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.575 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.575 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.572 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.572 | |
| 2wf2 | ZY2 | Beta-secretase 1 | 3.4.23.46 | 0.566 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.566 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.564 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.563 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.562 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.556 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.556 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.554 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.552 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.550 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.550 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.549 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.548 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.548 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.548 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.547 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.546 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.544 | |
| 2f3f | AXF | Beta-secretase 1 | 3.4.23.46 | 0.540 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.539 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.538 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.538 | |
| 2vie | VG0 | Beta-secretase 1 | 3.4.23.46 | 0.537 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.537 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.536 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.535 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.534 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.534 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.532 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.532 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.530 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.529 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.529 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.529 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.528 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.526 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.526 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.526 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.525 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.522 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.521 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.519 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.518 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.512 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.512 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.510 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.510 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.509 | |
| 3psy | RB9 | Endothiapepsin | 3.4.23.22 | 0.508 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.507 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.507 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.506 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.505 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.503 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.503 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.503 | |
| 1gvt | 2ZS | Endothiapepsin | 3.4.23.22 | 0.502 | |
| 1zap | A70 | Candidapepsin-2 | 3.4.23.24 | 0.502 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.502 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.500 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.500 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.499 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.499 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.499 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.499 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.498 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.497 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.497 | |
| 1w51 | L01 | Beta-secretase 1 | 3.4.23.46 | 0.496 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.496 | |
| 4lxm | 1YU | Beta-secretase 1 | 3.4.23.46 | 0.496 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.496 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.493 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.492 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.491 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.491 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.491 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.490 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.489 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.489 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.488 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.487 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.487 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.487 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.487 | |
| 4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.487 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.487 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.485 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.485 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.485 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.485 | |
| 3a20 | FMN | FMN-binding protein | / | 0.484 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.484 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.484 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.484 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.483 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 3pb5 | F63 | Endothiapepsin | 3.4.23.22 | 0.483 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.483 | |
| 4y45 | F91 | Endothiapepsin | 3.4.23.22 | 0.483 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.482 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.482 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.482 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.482 | |
| 4dus | 0MP | Beta-secretase 1 | 3.4.23.46 | 0.482 | |
| 2jjj | 0QS | Endothiapepsin | 3.4.23.22 | 0.481 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.480 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.479 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.479 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.478 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.477 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.477 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.477 | |
| 4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.477 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.476 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.476 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.475 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.475 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.475 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.475 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.475 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.474 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.474 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.473 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.472 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.472 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.472 | |
| 4xr9 | NAD | CalS8 | / | 0.471 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.470 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 4frs | 0V6 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.469 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.469 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.469 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.469 | |
| 4jld | ADP | Adenylate kinase | / | 0.469 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.468 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.468 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.468 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.468 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.468 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.467 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.467 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.467 | |
| 1gvw | 0EM | Endothiapepsin | 3.4.23.22 | 0.466 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.466 | |
| 1ppk | IVV | Penicillopepsin-1 | 3.4.23.20 | 0.466 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.466 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.466 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.465 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.465 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.465 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.465 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.465 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.464 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.464 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.464 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.464 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.464 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.464 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.463 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.462 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.462 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.462 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.462 | |
| 5dp2 | NAP | CurF | / | 0.462 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.461 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.461 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.461 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.461 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.461 | |
| 4yfy | 1YJ | VioF | / | 0.461 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.460 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.460 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.460 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.460 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.459 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.459 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.458 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.458 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.458 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.458 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.458 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.458 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.458 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.457 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.457 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.457 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.457 | |
| 4b70 | WM9 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.457 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.456 | |
| 2ejz | SAH | Diphthine synthase | / | 0.456 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.456 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3a3g | DLZ | Lumazine protein | / | 0.456 | |
| 3amf | FMN | FMN-binding protein | / | 0.456 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.456 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.456 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.456 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.456 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.456 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1eq2 | ADQ | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.455 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.455 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.455 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.455 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.455 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.455 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.455 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.455 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.455 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.455 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.455 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.455 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.454 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.454 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.454 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.454 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.454 | |
| 4fs4 | H24 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.454 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.454 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.454 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.454 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.453 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.453 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.453 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.453 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.453 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.453 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.453 | |
| 4kb9 | G79 | Protease | / | 0.453 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.453 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.453 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.453 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.452 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1eag | A70 | Candidapepsin-2 | 3.4.23.24 | 0.452 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.452 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3cyw | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.452 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.452 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.452 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.451 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.451 | |
| 2hux | SAH | Diphthine synthase | / | 0.451 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.451 | |
| 2zre | AGS | Protein RecA | / | 0.451 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.451 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.450 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.450 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.450 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1c70 | L75 | Protease | / | 0.449 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.449 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.449 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.449 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.449 | |
| 3mje | NDP | AmphB | / | 0.449 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.449 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.449 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.449 | |
| 4y57 | F63 | Endothiapepsin | 3.4.23.22 | 0.449 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.448 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.448 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2bxm | IMN | Serum albumin | / | 0.448 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.448 | |
| 2p3b | 3TL | V-1 protease | / | 0.448 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.448 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.448 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.447 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.447 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.447 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.447 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.447 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.446 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 2hut | SAH | Diphthine synthase | / | 0.446 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3e39 | FMN | Nitroreductase | / | 0.446 | |
| 3eku | CY9 | Actin-5C | / | 0.446 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.446 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.446 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.446 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.446 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.446 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.446 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1hzj | UD1 | UDP-glucose 4-epimerase | / | 0.445 | |
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.445 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.445 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.445 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.445 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.445 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.445 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.445 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.445 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.445 | |
| 5ftc | ADP | TPR domain protein | / | 0.445 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.444 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.444 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.444 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.444 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.444 | |
| 2e83 | FMN | FMN-binding protein | / | 0.444 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.444 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.444 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.443 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.443 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.443 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.443 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.443 | |
| 3ieu | GDP | GTPase Era | / | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.443 | |
| 3zlq | 6T9 | Beta-secretase 2 | 3.4.23.45 | 0.443 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.443 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1odx | 0E8 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.442 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.442 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.442 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.442 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.442 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.442 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.442 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.442 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1flm | FMN | FMN-binding protein | / | 0.441 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.441 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.441 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.441 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.441 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.441 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.441 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.441 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3e8x | NAP | BH1520 protein | / | 0.441 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.441 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.441 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.440 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.440 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.440 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 3a3b | RBF | Lumazine protein | / | 0.440 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.440 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.440 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.440 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 |