Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2qe2 | 452 | Polyprotein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2qe2 | 452 | Polyprotein | / | 1.000 | |
| 3ska | 053 | Genome polyprotein | 2.7.7.48 | 0.646 | |
| 3ske | 054 | Genome polyprotein | 2.7.7.48 | 0.599 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.591 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.587 | |
| 4iz0 | 2BI | Genome polyprotein | 2.7.7.48 | 0.581 | |
| 4ih6 | 1EP | Genome polyprotein | 2.7.7.48 | 0.574 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.570 | |
| 3d28 | B34 | Genome polyprotein | 2.7.7.48 | 0.570 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.567 | |
| 4mkb | 28V | Genome polyprotein | 2.7.7.48 | 0.567 | |
| 2gc8 | 885 | Polyprotein | / | 0.554 | |
| 4mka | 2AY | Genome polyprotein | 2.7.7.48 | 0.552 | |
| 3g86 | T18 | Genome polyprotein | 2.7.7.48 | 0.550 | |
| 3uph | 0C1 | Genome polyprotein | 2.7.7.48 | 0.550 | |
| 4mk7 | 28O | Genome polyprotein | 2.7.7.48 | 0.542 | |
| 3tyv | HI3 | Genome polyprotein | 2.7.7.48 | 0.541 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.539 | |
| 2giq | NN2 | Genome polyprotein | 2.7.7.48 | 0.528 | |
| 3br9 | DEY | Genome polyprotein | 2.7.7.48 | 0.526 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.519 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.519 | |
| 4mk9 | 28R | Genome polyprotein | 2.7.7.48 | 0.519 | |
| 3h5u | H5U | Genome polyprotein | 2.7.7.48 | 0.515 | |
| 3gyn | B42 | Genome polyprotein | 2.7.7.48 | 0.512 | |
| 3igv | B80 | Genome polyprotein | 2.7.7.48 | 0.511 | |
| 3upi | 0C2 | Genome polyprotein | 2.7.7.48 | 0.509 | |
| 3u4r | 08F | Genome polyprotein | 2.7.7.48 | 0.508 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.507 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.504 | |
| 4eaw | 0NQ | Genome polyprotein | 2.7.7.48 | 0.504 | |
| 3d5m | 4MS | Genome polyprotein | 2.7.7.48 | 0.502 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.499 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.498 | |
| 2qe5 | 617 | Polyprotein | / | 0.497 | |
| 3hkw | IX6 | Genome polyprotein | 2.7.7.48 | 0.497 | |
| 2emu | SAH | Diphthine synthase | / | 0.496 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.496 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.495 | |
| 2ejz | SAH | Diphthine synthase | / | 0.494 | |
| 2fvc | 888 | Polyprotein | / | 0.494 | |
| 3h5s | H5S | Genome polyprotein | 2.7.7.48 | 0.493 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.493 | |
| 2emr | SAH | Diphthine synthase | / | 0.492 | |
| 3e51 | N35 | Genome polyprotein | 2.7.7.48 | 0.489 | |
| 2e8h | SAH | Diphthine synthase | / | 0.488 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.488 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.486 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.486 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.486 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.485 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.484 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.484 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.484 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.483 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 3arv | SAU | Chitinase A | / | 0.483 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.482 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.480 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.479 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.479 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.478 | |
| 2eni | SAH | Diphthine synthase | / | 0.477 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.476 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.476 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 1yvf | PH7 | Polyprotein | / | 0.474 | |
| 2dsg | SAH | Diphthine synthase | / | 0.474 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.474 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 2ehl | SAH | Diphthine synthase | / | 0.473 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.473 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.473 | |
| 3h2l | YAK | Genome polyprotein | 2.7.7.48 | 0.472 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.471 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 2e07 | SAH | Diphthine synthase | / | 0.471 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.471 | |
| 2hux | SAH | Diphthine synthase | / | 0.470 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.470 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.470 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.469 | |
| 2p6l | SAH | Diphthine synthase | / | 0.469 | |
| 2pcm | SAH | Diphthine synthase | / | 0.469 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.469 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.469 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.468 | |
| 1vce | SAH | Diphthine synthase | / | 0.467 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.467 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.466 | |
| 2eeq | SAH | Diphthine synthase | / | 0.466 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.466 | |
| 2owu | SAH | Diphthine synthase | / | 0.465 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.465 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.464 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.464 | |
| 2dxv | SAH | Diphthine synthase | / | 0.464 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.464 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.464 | |
| 2en5 | SAH | Diphthine synthase | / | 0.463 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.463 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.463 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.462 | |
| 2dsh | SAH | Diphthine synthase | / | 0.462 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.462 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.461 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.461 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.461 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.461 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.460 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.460 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.460 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.460 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.460 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.460 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 2egl | SAH | Diphthine synthase | / | 0.459 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.459 | |
| 2huv | SAH | Diphthine synthase | / | 0.459 | |
| 2pch | SAH | Diphthine synthase | / | 0.459 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3kn0 | 3TO | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.458 | |
| 4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.458 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.457 | |
| 2dsi | SAH | Diphthine synthase | / | 0.457 | |
| 2e16 | SAH | Diphthine synthase | / | 0.457 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.457 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.457 | |
| 1wng | SAH | Diphthine synthase | / | 0.456 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.456 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.456 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.456 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.456 | |
| 3cde | N3H | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.456 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.456 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.456 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.456 | |
| 2dxw | SAH | Diphthine synthase | / | 0.455 | |
| 2p2x | SAH | Diphthine synthase | / | 0.455 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.455 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.455 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.455 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.455 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.455 | |
| 4lez | 1SY | Cyclic GMP-AMP synthase | / | 0.455 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.455 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.454 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 2e7r | SAH | Diphthine synthase | / | 0.454 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.454 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.454 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.454 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.453 | |
| 1b2r | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.452 | |
| 1z4u | PH9 | Polyprotein | / | 0.452 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.452 | |
| 2pci | SAH | Diphthine synthase | / | 0.452 | |
| 2pu2 | DK2 | Beta-lactamase | 3.5.2.6 | 0.452 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.452 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.452 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4yfy | 0FX | VioF | / | 0.452 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.452 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.451 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.451 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.451 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.451 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.451 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 2owk | SAH | Diphthine synthase | / | 0.451 | |
| 2p6k | SAH | Diphthine synthase | / | 0.451 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.451 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.451 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.451 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.451 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.451 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2ejk | SAH | Diphthine synthase | / | 0.450 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.450 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.450 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.450 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.450 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.450 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.450 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4cb7 | 41G | Polymerase basic protein 2 | / | 0.450 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.450 | |
| 5dp2 | NAP | CurF | / | 0.450 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.449 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.449 | |
| 2e8q | SAH | Diphthine synthase | / | 0.449 | |
| 2eld | SAH | Diphthine synthase | / | 0.449 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.449 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 2p6d | SAH | Diphthine synthase | / | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.449 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.448 | |
| 2e15 | SAH | Diphthine synthase | / | 0.448 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.448 | |
| 3eks | CY9 | Actin-5C | / | 0.448 | |
| 3h98 | B5P | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.448 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.447 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.447 | |
| 1rxj | BNI | Streptavidin | / | 0.447 | |
| 1til | ATP | Anti-sigma F factor | / | 0.447 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.447 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.447 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.447 | |
| 2jf6 | S55 | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.447 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.447 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4b1d | 6TG | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.447 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.447 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4y0k | NAP | AntE | / | 0.447 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.447 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.446 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 2pca | SAH | Diphthine synthase | / | 0.446 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.446 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.446 | |
| 3kr8 | XAV | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.446 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.446 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.446 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.446 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
| 1s4o | GDP | Glycolipid 2-alpha-mannosyltransferase | / | 0.445 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.445 | |
| 2e4n | SAH | Diphthine synthase | / | 0.445 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.445 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.445 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.444 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.444 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.444 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.444 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.444 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.444 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.444 | |
| 4bzr | K26 | Angiotensin-converting enzyme | 3.2.1 | 0.444 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.444 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.444 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.444 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.444 | |
| 1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.443 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.443 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.443 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.443 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.443 | |
| 2eka | SAH | Diphthine synthase | / | 0.443 | |
| 2ele | SAH | Diphthine synthase | / | 0.443 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.443 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 3bsa | 1PD | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.443 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.443 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.443 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.442 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.442 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.442 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.442 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.442 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.442 | |
| 2p6i | SAH | Diphthine synthase | / | 0.442 | |
| 2pck | SAH | Diphthine synthase | / | 0.442 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.442 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.442 | |
| 4f1y | CNI | Glutamate receptor 3 | / | 0.442 | |
| 4gv8 | DUP | DUTPase | / | 0.442 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3cw9 | 01A | 4-chlorobenzoyl CoA ligase | / | 0.441 | |
| 3e78 | TPP | High affinity transport system protein p37 | / | 0.441 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.441 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.441 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.440 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1j78 | VDY | Vitamin D-binding protein | / | 0.440 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.440 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.440 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.440 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.440 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.440 | |
| 3ghh | 2NF | CD38 molecule | / | 0.440 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3rbq | GLY_ALA_GLY_ALA_DAO | Protein unc-119 homolog A | / | 0.440 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.440 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.440 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bfq | 083 | Soluble acetylcholine receptor | / | 0.440 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.440 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 |