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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2f8pCEIObelin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2f8pCEIObelin/1.000
4mryCEIObelin/0.599
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.519
3cseN22Uncharacterized protein/0.513
2xvv9DNSerum albumin/0.511
1upw444Oxysterols receptor LXR-beta/0.502
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.498
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.496
2cd2FOLDihydrofolate reductase1.5.1.30.495
1x8lOXRRetinol dehydratase/0.490
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.490
1fmlRTLRetinol dehydratase/0.488
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.488
1crbRTLRetinol-binding protein 1/0.486
1ndzFR5Adenosine deaminase3.5.4.40.486
3ddw055Glycogen phosphorylase, liver form2.4.1.10.484
1nhz486Glucocorticoid receptor/0.483
3zkyWT4Isopenicillin N synthase1.21.3.10.483
3b9lAZZSerum albumin/0.482
1s3yTQTDihydrofolate reductase1.5.1.30.481
3eem53VUncharacterized protein/0.480
4eiyZMAAdenosine receptor A2a/0.480
2vqqTFGHistone deacetylase 43.5.1.980.479
3vt7VDXVitamin D3 receptor/0.479
1yrdCAMCamphor 5-monooxygenase1.14.15.10.478
1dz6CAMCamphor 5-monooxygenase1.14.15.10.477
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.477
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.477
4i9i1DYTankyrase-12.4.2.300.477
4udaDEXMineralocorticoid receptor/0.477
1ly3COGDihydrofolate reductase1.5.1.30.476
3drcMTXDihydrofolate reductase1.5.1.30.476
3fznD7KBenzoylformate decarboxylase4.1.1.70.476
4li71XPTankyrase-12.4.2.300.476
2bxqIMNSerum albumin/0.475
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.474
1bk0ACVIsopenicillin N synthase1.21.3.10.474
1s3uTQDDihydrofolate reductase1.5.1.30.474
4ia1BIVVitamin D3 receptor A/0.474
4j6cSTRCytochrome P450 monooxygenase/0.474
1blzACVIsopenicillin N synthase1.21.3.10.473
4iarERM5-hydroxytryptamine receptor 1B/0.473
1ry0PG2Aldo-keto reductase family 1 member C3/0.472
3otwCOAPhosphopantetheine adenylyltransferase/0.472
3tk3CPZCytochrome P450 2B41.14.14.10.472
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.472
1dajMOTDihydrofolate reductase1.5.1.30.471
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.471
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.471
4kfj1R0Dihydrofolate reductase1.5.1.30.471
1e26GPBDihydrofolate reductase1.5.1.30.470
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
2xegCI9Glutamate carboxypeptidase 23.4.17.210.470
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.470
4j7xSASSepiapterin reductase1.1.1.1530.470
1yw8A75Methionine aminopeptidase 2/0.469
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.469
3eej53RUncharacterized protein/0.469
1kmvLIIDihydrofolate reductase1.5.1.30.468
1opbRETRetinol-binding protein 2/0.468
1txiTX5Vitamin D3 receptor/0.468
2m56CAMCamphor 5-monooxygenase1.14.15.10.468
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.468
2zbaZBATrichothecene 3-O-acetyltransferase/0.468
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.468
5hs1VORLanosterol 14-alpha demethylase/0.468
1synF89Thymidylate synthase/0.467
4b1fKRHGlutamate racemase/0.467
4bb3KKAIsopenicillin N synthase1.21.3.10.467
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.467
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.467
4j6dTESCytochrome P450 monooxygenase/0.467
4la0198Serum albumin/0.467
4pztSOPHistone acetyltransferase p300/0.467
1fkoEFZGag-Pol polyprotein2.7.7.490.466
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.466
2f3815MAldo-keto reductase family 1 member C3/0.466
2feuCAMCamphor 5-monooxygenase1.14.15.10.466
3nu03TUDihydrofolate reductase1.5.1.30.466
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
3uvvREARetinoic acid receptor RXR-alpha/0.466
4jlt8PRCytochrome P450 2B41.14.14.10.466
2ij7TPFMycocyclosin synthase1.14.21.90.465
4dbuBT9Aldo-keto reductase family 1 member C3/0.465
1pd9CO4Dihydrofolate reductase1.5.1.30.464
1ppjANYCytochrome b/0.464
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.464
4cfkLY2Bromodomain-containing protein 4/0.464
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.464
3sn6P0GBeta-2 adrenergic receptor/0.464
1ie8KH1Vitamin D3 receptor/0.463
1ly4COQDihydrofolate reductase1.5.1.30.463
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.463
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.463
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2jfz003Glutamate racemase/0.463
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.463
3elm24FCollagenase 33.4.240.463
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.463
1kmsLIHDihydrofolate reductase1.5.1.30.462
1p8dCO1Oxysterols receptor LXR-beta/0.462
1rkhVD2Vitamin D3 receptor/0.462
2fzhDH1Dihydrofolate reductase1.5.1.30.462
2p20PRXAcetyl-coenzyme A synthetase/0.462
2y60M8FIsopenicillin N synthase1.21.3.10.462
3fwjCAMCamphor 5-monooxygenase1.14.15.10.462
3t3q9PLCytochrome P450 2A61.14.130.462
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.462
4kebFOLDihydrofolate reductase1.5.1.30.462
1ay0TPPTransketolase 12.2.1.10.461
1qvuPRLHTH-type transcriptional regulator QacR/0.461
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
3fwfCAMCamphor 5-monooxygenase1.14.15.10.461
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.461
3v49PK0Androgen receptor/0.461
4dk70KSOxysterols receptor LXR-beta/0.461
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
4y1bNAPAntE/0.461
1uzwCDHIsopenicillin N synthase1.21.3.10.460
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2fzjDH3Dihydrofolate reductase1.5.1.30.460
2qbmCAMCamphor 5-monooxygenase1.14.15.10.460
3nxyD2HDihydrofolate reductase1.5.1.30.460
4jbtASDCytochrome P450 monooxygenase/0.460
4kkyCAMCamphor 5-monooxygenase1.14.15.10.460
1dr3HBIDihydrofolate reductase1.5.1.30.459
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.459
1mvsDTMDihydrofolate reductase1.5.1.30.459
1pq944BOxysterols receptor LXR-beta/0.459
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.459
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.459
2zb8IMNProstaglandin reductase 21.3.1.480.459
3fwiCAMCamphor 5-monooxygenase1.14.15.10.459
3gwfNAPCyclohexanone monooxygenase/0.459
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.459
4jlm1NNDeoxycytidine kinase2.7.1.740.459
4y8wSTRSteroid 21-hydroxylase/0.459
1ikvEFZGag-Pol polyprotein2.7.7.490.458
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1mczRMNBenzoylformate decarboxylase4.1.1.70.458
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.458
2aclL05Oxysterols receptor LXR-alpha/0.458
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.458
3c1xCKKHepatocyte growth factor receptor2.7.10.10.458
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.458
3ghvGHCDihydrofolate reductase1.5.1.30.458
3pd4A3GThreonine--tRNA ligase6.1.1.30.458
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.458
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.458
5k2bZMAAdenosine receptor A2a/0.458
1qiqACCIsopenicillin N synthase1.21.3.10.457
1tsdF89Thymidylate synthase/0.457
1wxyFRKAdenosine deaminase3.5.4.40.457
2ow9SP6Collagenase 33.4.240.457
2ykeYKEHeat shock protein HSP 90-alpha/0.457
2zb45OPProstaglandin reductase 21.3.1.480.457
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
3nljJRRNitric oxide synthase, brain1.14.13.390.457
3ntz3TZDihydrofolate reductase1.5.1.30.457
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
3s3vTOPDihydrofolate reductase1.5.1.30.457
3w5p4OAVitamin D3 receptor/0.457
3zrbORCProgesterone receptor/0.457
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.457
4boeCLRJapanin/0.457
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
4h9814QUncharacterized protein/0.457
5iua6DXAdenosine receptor A2a/0.457
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1fm4DXCMajor pollen allergen Bet v 1-L/0.456
1s19MC9Vitamin D3 receptor/0.456
1v79FR7Adenosine deaminase3.5.4.40.456
2abi1CAMineralocorticoid receptor/0.456
3gdsVAL_TYR_TYR_PHESerine endoprotease DegS3.4.21.1070.456
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.456
3vf60H6Glucokinase2.7.1.20.456
3vt45YIVitamin D3 receptor/0.456
3wrhCAMCamphor 5-monooxygenase1.14.15.10.456
4a83DXCMajor pollen allergen Bet v 1-A/0.456
1diuBDMDihydrofolate reductase1.5.1.30.455
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1gjrNAPFerredoxin--NADP reductase1.18.1.20.455
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
1pq6965Oxysterols receptor LXR-beta/0.455
1r2jFADFkbI/0.455
2xvw9NRSerum albumin/0.455
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
3l5dBDVBeta-secretase 13.4.23.460.455
3l63CAMCamphor 5-monooxygenase1.14.15.10.455
3p9tTCLRepressor/0.455
4e0u0MVCyclic dipeptide N-prenyltransferase/0.455
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.455
4g8bHL6Alpha/beta hydrolase fold protein/0.455
1axwMTXThymidylate synthase/0.454
1hniAAAGag-Pol polyprotein2.7.7.490.454
1l2jETCEstrogen receptor beta/0.454
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.454
1q5dEPBEpothilone C/D epoxidase1.140.454
1s36CEIObelin/0.454
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.454
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.454
2ewaSB2Mitogen-activated protein kinase 14/0.454
2fpcSCGStrictosidine synthase4.3.3.20.454
2qimZEAClass 10 plant pathogenesis-related protein/0.454
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3td8D2RDihydrofolate reductase1.5.1.30.454
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.454
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.454
4j6bPLOCytochrome P450 monooxygenase/0.454
4jubTPPBenzoylformate decarboxylase4.1.1.70.454
4ys22BAUncharacterized protein/0.454
5g53NECAdenosine receptor A2a/0.454
1dhiMTXDihydrofolate reductase1.5.1.30.453
1dz8CAMCamphor 5-monooxygenase1.14.15.10.453
1mrqSTRAldo-keto reductase family 1 member C1/0.453
1obnASVIsopenicillin N synthase1.21.3.10.453
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1s9qOHTEstrogen-related receptor gamma/0.453
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.453
1vyrFMNPentaerythritol tetranitrate reductase/0.453
1w06W05Isopenicillin N synthase1.21.3.10.453
2ea2F77Methionine aminopeptidase 2/0.453
2gpvOHTEstrogen-related receptor gamma/0.453
2vcmM11Isopenicillin N synthase1.21.3.10.453
2z97CAMCamphor 5-monooxygenase1.14.15.10.453
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3gyf51PDihydrofolate reductase1.5.1.30.453
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
3t3r9PLCytochrome P450 2A61.14.130.453
4jq4IMNAldo-keto reductase family 1 member C2/0.453
4l4eCAMCamphor 5-monooxygenase1.14.15.10.453
4m6l21VDihydrofolate reductase1.5.1.30.453
1a72PADAlcohol dehydrogenase E chain1.1.1.10.452
1aobDDUThymidylate synthase/0.452
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.452
1ysx4EBSerum albumin/0.452
1zdwFLVPrenyltransferase/0.452
2q7kTESAndrogen receptor/0.452
2vrbNAPTriphenylmethane reductase/0.452
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3fwgCAMCamphor 5-monooxygenase1.14.15.10.452
4bfpSWYTankyrase-22.4.2.300.452
4k4eK4ETankyrase-12.4.2.300.452
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
1jtqLY3Thymidylate synthase/0.451
1jutLYDThymidylate synthase/0.451
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.451
1tkaN3TTransketolase 12.2.1.10.451
1xq3R18Androgen receptor/0.451
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2a3iC0RMineralocorticoid receptor/0.451
2p7zOHTEstrogen-related receptor gamma/0.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
2q7iTESAndrogen receptor/0.451
2v5aLZLBiotin carboxylase6.3.4.140.451
3fp0FP015-O-acetyltransferase/0.451
3nmpPYVAbscisic acid receptor PYL2/0.451
3oafOAGDihydrofolate reductase1.5.1.30.451
3och2MXDihydrofolate reductase1.5.1.30.451
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.451
3uptTPPTransketolase/0.451
3zoiM2WIsopenicillin N synthase1.21.3.10.451
4fhi0S4Vitamin D3 receptor A/0.451
4mrxCZHObelin/0.451
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.451
4rrgA3TThreonine--tRNA ligase6.1.1.30.451
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.451
5c1mCLRMu-type opioid receptor/0.451
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.451
3emlZMAAdenosine receptor A2a/0.451
1cjtFOKAdenylate cyclase type 2/0.450
1cjtFOKAdenylate cyclase type 5/0.450
1osvCHCBile acid receptor/0.450
1rtiHEFGag-Pol polyprotein2.7.7.490.450
1uhlMEIRetinoic acid receptor RXR-beta/0.450
1xmmM7Gm7GpppX diphosphatase3.6.1.590.450
2aclREARetinoic acid receptor RXR-alpha/0.450
2p15EZTEstrogen receptor/0.450
2w3aTOPDihydrofolate reductase1.5.1.30.450
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
2zznSAMtRNA (guanine(37)-N1)-methyltransferase Trm5b2.1.1.2280.450
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3eel53TUncharacterized protein/0.450
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3qlrNDPDihydrofolate reductase1.5.1.30.450
3qm4PN0Cytochrome P450 2D6/0.450
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.450
3t0kDCQSulfide-quinone reductase/0.450
3zhvTDWMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.450
3zkuHCVIsopenicillin N synthase1.21.3.10.450
4i8vBHFCytochrome P450 1A11.14.14.10.450
4ia7BIVVitamin D3 receptor A/0.450
4iteTEYVitamin D3 receptor/0.450
4l0qNADAlcohol dehydrogenase class-3/0.450
4mfb29TGag-Pol polyprotein2.7.7.490.450
5stdUNNScytalone dehydratase4.2.1.940.450
1fm69CRRetinoic acid receptor RXR-alpha/0.449
1ludTRRDihydrofolate reductase1.5.1.30.449
1mznBM6Retinoic acid receptor RXR-alpha/0.449
1qknRALEstrogen receptor beta/0.449
1x2hLPALipoate-protein ligase A6.3.1.200.449
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.449
2iviACWIsopenicillin N synthase1.21.3.10.449
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2vbpVB1Isopenicillin N synthase1.21.3.10.449
2w9hTOPDihydrofolate reductase1.5.1.30.449
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2zlcVDXVitamin D3 receptor/0.449
3f0aACOSpermidine N(1)-acetyltransferase/0.449
3h0a9RARetinoic acid receptor RXR-alpha/0.449
3kdiA8SAbscisic acid receptor PYL2/0.449
3mdmFJZCholesterol 24-hydroxylase/0.449
3tdaPN0Cytochrome P450 2D6/0.449
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
1m9m6NINitric oxide synthase, endothelial1.14.13.390.448
1zg32HIIsoflavone 4'-O-methyltransferase/0.448
2bu9HFVIsopenicillin N synthase1.21.3.10.448
2ft9CHDFatty acid-binding protein 2, liver/0.448
2hl1A3SThreonine--tRNA ligase6.1.1.30.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.448
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
2y67N21UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
3aosJH2Hemolymph juvenile hormone binding protein/0.448
3b9oFMNAlkane monoxygenase/0.448
3fu83DMLaccase-11.10.3.20.448
3gphOIDCytochrome P450 2E11.14.130.448
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
3u8hBHPPhospholipase A2, membrane associated/0.448
4hdrDMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase/0.448
4hdrDMDArsB/0.448
4mt92D6Tankyrase-12.4.2.300.448
4twnB96Ephrin type-A receptor 32.7.10.10.448
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.447
1bim0QBRenin3.4.23.150.447
1odnAPVIsopenicillin N synthase1.21.3.10.447
1p6jDP9Nitric oxide synthase, brain1.14.13.390.447
1qjfACSIsopenicillin N synthase1.21.3.10.447
1ry8RUTAldo-keto reductase family 1 member C3/0.447
1t85CAMCamphor 5-monooxygenase1.14.15.10.447
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.447
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.447
2hxzH7JCathepsin S3.4.22.270.447
2pnuENMAndrogen receptor/0.447
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.447
2r6jNDPEugenol synthase 11.1.1.3180.447
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.447
3qizQI2Botulinum neurotoxin type A3.4.24.690.447
3s79ASDAromatase1.14.14.140.447
4c9wVGH7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.447
4ek1CAMCamphor 5-monooxygenase1.14.15.10.447
4j21AJ6Tankyrase-22.4.2.300.447
4k6i9RARetinoic acid receptor RXR-alpha/0.447
4r1lADPPhenylacetate-coenzyme A ligase/0.447
5k2aZMAAdenosine receptor A2a/0.447
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
1hb1OCVIsopenicillin N synthase1.21.3.10.446
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.446
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1rctNOSPurine nucleoside phosphorylase2.4.2.10.446
1s3vTQDDihydrofolate reductase1.5.1.30.446
1t87CAMCamphor 5-monooxygenase1.14.15.10.446
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
2p2qPRXAcetyl-coenzyme A synthetase/0.446
2qbnCAMCamphor 5-monooxygenase1.14.15.10.446
2rqfJH3Hemolymph juvenile hormone binding protein/0.446
3f4bTCLEnoyl-acyl carrier protein reductase/0.446
3is9AC7Gag-Pol polyprotein2.7.7.490.446
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.446
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3p3zP3ZPutative cytochrome P450/0.446
3t1a5MAGag-Pol polyprotein2.7.7.490.446
3vtdTKDVitamin D3 receptor/0.446
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.446
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4dc0NDPPutative ketoacyl reductase1.3.10.446
4e37NDPCatalase1.11.1.60.446
4hkiFLNTankyrase-22.4.2.300.446
1hfqMOTDihydrofolate reductase1.5.1.30.445
1rx8FOLDihydrofolate reductase1.5.1.30.445
2gesCOKPantothenate kinase2.7.1.330.445
3akn11DFatty acid-binding protein, intestinal/0.445
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.445
3nxrD2DDihydrofolate reductase1.5.1.30.445
3q9bB3NAcetylpolyamine amidohydrolase/0.445
3qfcNAPNADPH--cytochrome P450 reductase/0.445
3vt9YI4Vitamin D3 receptor/0.445
3w5rLOAVitamin D3 receptor/0.445
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.445
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4iyg1HUStrictosidine synthase4.3.3.20.445
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4tkg09LTankyrase-22.4.2.300.445
1fkxPRHAdenosine deaminase3.5.4.40.444
1uyuCAMCamphor 5-monooxygenase1.14.15.10.444
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.444
2o4rVD5Vitamin D3 receptor/0.444
2r0pK2CPutative FAD-monooxygenase/0.444
2yhdTESAndrogen receptor/0.444
3junAKDPhenazine biosynthesis protein A/B/0.444
3nr4PYVAbscisic acid receptor PYL2/0.444
3rpnGTXGlutathione S-transferase kappa 12.5.1.180.444
3vg9ZMAAdenosine receptor A2a/0.444
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.444
4alhA9PBromodomain-containing protein 2/0.444
4bfzZVZPantothenate kinase2.7.1.330.444
4ead0NPThymidine phosphorylase2.4.2.40.444
4pkl1GHUncharacterized protein/0.444
4pnmNU1Tankyrase-22.4.2.300.444
4stdBFSScytalone dehydratase4.2.1.940.444
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.444
1felFENRetinol-binding protein 4/0.443
1fvpFMANon-fluorescent flavoprotein/0.443
1hfrMOTDihydrofolate reductase1.5.1.30.443
1n0uSO1Elongation factor 2/0.443
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.443
1rftPXMPyridoxal kinase2.7.1.350.443
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.443
1sr7MOFProgesterone receptor/0.443
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.443
2g1n1IGRenin3.4.23.150.443
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
2pklDHTAndrogen receptor/0.443
2vqoTFGHistone deacetylase 43.5.1.980.443
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2yhuWHFPteridine reductase/0.443
3da24MDCarbonic anhydrase 134.2.1.10.443
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
3ielU5PRibonuclease TTHA02523.10.443
3vrwYS5Vitamin D3 receptor/0.443
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.443
4apuOR8Progesterone receptor/0.443
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.443
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
4knjE1FCarbonic anhydrase 24.2.1.10.443
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.443
6cp4CAMCamphor 5-monooxygenase1.14.15.10.443
1h51FMNPentaerythritol tetranitrate reductase/0.442
1og5SWFCytochrome P450 2C9/0.442
1p0pBCHCholinesterase3.1.1.80.442
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1umlFR4Adenosine deaminase3.5.4.40.442
2b1z17MEstrogen receptor/0.442
2cl5BIECatechol O-methyltransferase2.1.1.60.442
2op07PCEnoyl-ACP reductase/0.442
2re8GSUGlutamine--tRNA ligase6.1.1.180.442
3ghh2NFCD38 molecule/0.442
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.442
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
3lkhLT6Genome polyprotein2.7.7.480.442
3njoP2MAbscisic acid receptor PYR1/0.442
3nxvD2FDihydrofolate reductase1.5.1.30.442
3qj0QI3Botulinum neurotoxin type A3.4.24.690.442
3vtcTK3Vitamin D3 receptor/0.442
4cjfRVNIntegrase/0.442
4g210VPVitamin D3 receptor A/0.442
4g8cC6LAlpha/beta hydrolase fold protein/0.442
4h4m494Gag-Pol polyprotein2.7.7.490.442
4jhz1KVBeta-glucuronidase3.2.1.310.442
4jx1CAMCamphor 5-monooxygenase1.14.15.10.442
4kwhNAPReductase homolog/0.442
4l4dCAMCamphor 5-monooxygenase1.14.15.10.442
4x3uSVRChromobox protein homolog 7/0.442
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.441
1o5rFR9Adenosine deaminase3.5.4.40.441
1pkfEPDEpothilone C/D epoxidase1.140.441
1t7rDHTAndrogen receptor/0.441
1uyhPU0Heat shock protein HSP 90-alpha/0.441
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
2gpuOHTEstrogen-related receptor gamma/0.441
2rhrEMOPutative ketoacyl reductase1.3.10.441
2xtbKRMAdenosine kinase, putative/0.441
2y6fM9FIsopenicillin N synthase1.21.3.10.441
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.441
3bjhNBBOdorant binding protein ASP1/0.441
3c3xNAPEugenol synthase 11.1.1.3180.441
3dolGWIPol protein/0.441
4a81DXCMajor pollen allergen Bet v 1-A/0.441
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.441
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.441
4jlj1NMDeoxycytidine kinase2.7.1.740.441
4k38SAMAnaerobic sulfatase-maturating enzyme1.8.980.441
4qa0SHHHistone deacetylase 83.5.1.980.441
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.441
5kf2COAPredicted acetyltransferase/0.441
1a8t061Metallo-beta-lactamase type 2/0.440
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.440
1dhfFOLDihydrofolate reductase1.5.1.30.440
1e79ADPATP synthase subunit alpha, mitochondrial/0.440
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1v7aFRCAdenosine deaminase3.5.4.40.440
1x1aSAMC-20 methyltransferase/0.440
2a1nCAMCamphor 5-monooxygenase1.14.15.10.440
2aa5STRMineralocorticoid receptor/0.440
2bn4FADNADPH--cytochrome P450 reductase/0.440
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.440
2g1pSAHDNA adenine methylase2.1.1.720.440
2nnqT4BFatty acid-binding protein, adipocyte/0.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
2ykjYKJHeat shock protein HSP 90-alpha/0.440
2zaxCAMCamphor 5-monooxygenase1.14.15.10.440
3br3ETHTH-type transcriptional regulator QacR/0.440
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3d90NOGProgesterone receptor/0.440
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3gwfFADCyclohexanone monooxygenase/0.440
3h3qH13Collagen type IV alpha-3-binding protein/0.440
3h3sH15Collagen type IV alpha-3-binding protein/0.440
3ufsHW6Nitric oxide synthase, brain1.14.13.390.440
3vhuSNLMineralocorticoid receptor/0.440
3vtbTKAVitamin D3 receptor/0.440
3wrjCAMCamphor 5-monooxygenase1.14.15.10.440
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4ia3BIVVitamin D3 receptor A/0.440
4kak06UDihydrofolate reductase1.5.1.30.440
4l4fCAMCamphor 5-monooxygenase1.14.15.10.440
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.440
5cuqNSCGenome polyprotein/0.440
5uviZMAAdenosine receptor A2a/0.440
5jtbZMAAdenosine receptor A2a/0.440