sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 1.000 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.652 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.608 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.500 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.488 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.487 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.487 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.486 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.486 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.484 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.482 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.481 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.479 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.478 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.478 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.477 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.477 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.475 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.474 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.474 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.473 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.473 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.472 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.471 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.470 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.470 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.468 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.468 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.467 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.467 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.467 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.466 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.466 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.466 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.466 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.465 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.465 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.464 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.464 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.464 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.464 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.464 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.463 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.462 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.462 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.462 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.461 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.461 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.461 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.461 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.461 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.461 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.460 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.460 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.460 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.460 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.459 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.459 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.459 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.459 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.459 | |
| 5ftf | ADP | TPR domain protein | / | 0.459 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.458 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.458 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.458 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.458 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.457 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.457 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.457 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.456 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.456 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.456 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.456 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.455 | |
| 1c6y | MK1 | Protease | / | 0.454 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.454 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.454 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.454 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.453 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.453 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.453 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.453 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.453 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.453 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.452 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.452 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.452 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.452 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.452 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.451 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.451 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.450 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.450 | |
| 3u9e | COA | Lmo1369 protein | / | 0.450 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.450 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.450 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.449 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.449 | |
| 1mr9 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.449 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2ejz | SAH | Diphthine synthase | / | 0.449 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.449 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.449 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.449 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.448 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.448 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3ckq | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.448 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.448 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.448 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.448 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.447 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.447 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.447 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.447 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.447 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4ca6 | 3EF | Angiotensin-converting enzyme | 3.2.1 | 0.447 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.446 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.446 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.445 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.445 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.445 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.445 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.445 | |
| 4lut | DCS | Alanine racemase | / | 0.445 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
| 4y7c | NAP | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.445 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.444 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.444 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.444 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.444 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.444 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.444 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.443 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.443 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.443 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.443 | |
| 4tlz | NAP | KtzI | / | 0.443 | |
| 4zwe | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.443 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.443 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.442 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.442 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.442 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.442 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.442 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.442 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.442 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.441 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.441 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.441 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.441 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.441 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.441 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.441 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.441 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.441 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.440 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.440 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.440 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.440 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.440 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.440 |