Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dv5 | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2dv5 | SAH | Diphthine synthase | / | 1.000 | |
| 2dsi | SAH | Diphthine synthase | / | 0.875 | |
| 2p5c | SAH | Diphthine synthase | / | 0.871 | |
| 2owg | SAH | Diphthine synthase | / | 0.823 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.819 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.817 | |
| 2e15 | SAH | Diphthine synthase | / | 0.813 | |
| 2hut | SAH | Diphthine synthase | / | 0.808 | |
| 2p6i | SAH | Diphthine synthase | / | 0.806 | |
| 2p5f | SAH | Diphthine synthase | / | 0.802 | |
| 2pck | SAH | Diphthine synthase | / | 0.801 | |
| 2dxx | SAH | Diphthine synthase | / | 0.799 | |
| 2owk | SAH | Diphthine synthase | / | 0.799 | |
| 2p9d | SAH | Diphthine synthase | / | 0.785 | |
| 2e7r | SAH | Diphthine synthase | / | 0.768 | |
| 2huv | SAH | Diphthine synthase | / | 0.765 | |
| 2e8r | SAH | Diphthine synthase | / | 0.763 | |
| 2huq | SAH | Diphthine synthase | / | 0.754 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.752 | |
| 2p6k | SAH | Diphthine synthase | / | 0.750 | |
| 2e17 | SAH | Diphthine synthase | / | 0.744 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.741 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.740 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.735 | |
| 2p2x | SAH | Diphthine synthase | / | 0.735 | |
| 2ejk | SAH | Diphthine synthase | / | 0.733 | |
| 2eeq | SAH | Diphthine synthase | / | 0.728 | |
| 2eni | SAH | Diphthine synthase | / | 0.724 | |
| 2pca | SAH | Diphthine synthase | / | 0.722 | |
| 2egs | SAH | Diphthine synthase | / | 0.712 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.706 | |
| 2owu | SAH | Diphthine synthase | / | 0.706 | |
| 2dsh | SAH | Diphthine synthase | / | 0.703 | |
| 2ele | SAH | Diphthine synthase | / | 0.703 | |
| 2pcg | SAH | Diphthine synthase | / | 0.698 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.688 | |
| 2dsg | SAH | Diphthine synthase | / | 0.684 | |
| 2z6r | SAH | Diphthine synthase | / | 0.683 | |
| 2pch | SAH | Diphthine synthase | / | 0.681 | |
| 2e07 | SAH | Diphthine synthase | / | 0.679 | |
| 2el3 | SAH | Diphthine synthase | / | 0.678 | |
| 1wng | SAH | Diphthine synthase | / | 0.675 | |
| 2emu | SAH | Diphthine synthase | / | 0.671 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.669 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.666 | |
| 2ehl | SAH | Diphthine synthase | / | 0.666 | |
| 2el0 | SAH | Diphthine synthase | / | 0.664 | |
| 2e08 | SAH | Diphthine synthase | / | 0.662 | |
| 2e4n | SAH | Diphthine synthase | / | 0.661 | |
| 2p6d | SAH | Diphthine synthase | / | 0.661 | |
| 2dxv | SAH | Diphthine synthase | / | 0.658 | |
| 2dxw | SAH | Diphthine synthase | / | 0.657 | |
| 1vce | SAH | Diphthine synthase | / | 0.655 | |
| 2ejj | SAH | Diphthine synthase | / | 0.655 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.653 | |
| 2eld | SAH | Diphthine synthase | / | 0.651 | |
| 2emr | SAH | Diphthine synthase | / | 0.651 | |
| 2eka | SAH | Diphthine synthase | / | 0.641 | |
| 2pci | SAH | Diphthine synthase | / | 0.640 | |
| 2egb | SAH | Diphthine synthase | / | 0.639 | |
| 2e8h | SAH | Diphthine synthase | / | 0.632 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.627 | |
| 2hux | SAH | Diphthine synthase | / | 0.615 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.613 | |
| 2e8s | SAH | Diphthine synthase | / | 0.604 | |
| 2pcm | SAH | Diphthine synthase | / | 0.604 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.581 | |
| 2e8q | SAH | Diphthine synthase | / | 0.578 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.573 | |
| 2dek | SAH | Diphthine synthase | / | 0.572 | |
| 2egl | SAH | Diphthine synthase | / | 0.569 | |
| 2ejz | SAH | Diphthine synthase | / | 0.567 | |
| 2owf | SAH | Diphthine synthase | / | 0.566 | |
| 2e16 | SAH | Diphthine synthase | / | 0.561 | |
| 2owv | SAH | Diphthine synthase | / | 0.557 | |
| 2p6l | SAH | Diphthine synthase | / | 0.556 | |
| 2en5 | SAH | Diphthine synthase | / | 0.553 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.535 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.505 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.501 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.493 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.491 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.488 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.487 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.486 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.485 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.485 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.485 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.482 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.481 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.479 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.479 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.478 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.478 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.474 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.474 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.474 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.474 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.473 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.471 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.470 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.469 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.469 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.468 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.468 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.468 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.467 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.467 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.466 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.465 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.465 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.464 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.464 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.464 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.463 | |
| 5dp2 | NAP | CurF | / | 0.463 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.462 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.462 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.462 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.462 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.462 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.461 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.461 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.461 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.461 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.461 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.461 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.460 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.460 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.460 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.459 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.459 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.459 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.459 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.458 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.458 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.458 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.458 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.458 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.457 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.457 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.457 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.457 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.457 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.457 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.456 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.456 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.456 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.455 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.455 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.455 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.455 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2y65 | ADP | Kinesin heavy chain | / | 0.455 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.455 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.455 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.455 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.454 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.454 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.454 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.454 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.454 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.454 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.453 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.453 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.452 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.452 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.452 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.452 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.452 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.452 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.451 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.451 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4irn | FAD | AnaB | / | 0.451 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.451 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.450 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.450 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.450 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.450 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.450 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.450 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.449 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.449 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.449 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.449 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.449 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 4qec | NAP | ElxO | / | 0.448 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.448 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.447 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.447 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.447 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.447 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.447 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.447 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.447 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.446 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.446 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.446 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.446 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.445 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.445 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.445 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.445 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 2zts | ADP | Uncharacterized protein | / | 0.445 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.445 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.445 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.445 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.445 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.445 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.445 | |
| 1eio | GCH | Gastrotropin | / | 0.444 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.444 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.444 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3ieu | GDP | GTPase Era | / | 0.444 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.444 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.444 | |
| 5doz | NDP | JamJ | / | 0.444 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.443 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.443 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.443 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.443 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.443 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3oee | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 3oee | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.443 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.443 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.443 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.443 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.442 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.442 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.442 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.442 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.442 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.442 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4yqf | GDP | Septin-9 | / | 0.442 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.442 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.441 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.441 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1xef | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.441 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.441 | |
| 2xvu | 9DN | Serum albumin | / | 0.441 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.441 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.441 | |
| 3bnk | FMN | Flavoredoxin | / | 0.441 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.441 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.441 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.441 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.441 | |
| 3u9e | COA | Lmo1369 protein | / | 0.441 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.441 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.440 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2y3r | TIR | TamL | / | 0.440 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.440 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.440 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.440 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.440 |