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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1w6yEQUSteroid Delta-isomerase5.3.3.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1w6yEQUSteroid Delta-isomerase5.3.3.11.000
1e3vDXCSteroid Delta-isomerase5.3.3.10.644
1oh0EQUSteroid Delta-isomerase5.3.3.10.629
3owsEQUSteroid Delta-isomerase5.3.3.10.591
1gs3EQUSteroid Delta-isomerase5.3.3.10.587
3fzwEQUSteroid Delta-isomerase5.3.3.10.572
3nhxASDSteroid Delta-isomerase5.3.3.10.572
3owyEQUSteroid Delta-isomerase5.3.3.10.571
1e3rANDSteroid Delta-isomerase5.3.3.10.569
1ogxEQUSteroid Delta-isomerase5.3.3.10.569
1cqsEQUSteroid Delta-isomerase5.3.3.10.562
3owuEQUSteroid Delta-isomerase5.3.3.10.529
3vgnFNNSteroid Delta-isomerase5.3.3.10.529
1ohoEQUSteroid Delta-isomerase5.3.3.10.511
3zk5Z18Cytochrome P450 monooxygenase PikC/0.508
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.508
3tm5SFGUncharacterized protein/0.505
4jrvKJVEpidermal growth factor receptor2.7.10.10.502
3juqAJDPhenazine biosynthesis protein A/B/0.497
3iptEQUSteroid Delta-isomerase5.3.3.10.496
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.493
3nj0PYVAbscisic acid receptor PYL2/0.492
4ap3FADSteroid monooxygenase/0.491
3nmpPYVAbscisic acid receptor PYL2/0.490
2x7gPVBSRSF protein kinase 22.7.11.10.488
4iyg1HUStrictosidine synthase4.3.3.20.485
3kb0A8SAbscisic acid receptor PYL2/0.484
4qa1B3NHistone deacetylase 83.5.1.980.484
4oicA8SBet v I allergen-like/0.482
2fpcSCGStrictosidine synthase4.3.3.20.481
2a1nCAMCamphor 5-monooxygenase1.14.15.10.480
2j5sKTAAlr4455 protein/0.480
4c9pCAMCytochrome P450/0.480
4jq8KJ8Epidermal growth factor receptor2.7.10.10.480
1w7h3IPMitogen-activated protein kinase 14/0.478
1njbUMPThymidylate synthase/0.477
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.476
2itqITQEpidermal growth factor receptor2.7.10.10.476
3kb3A8SAbscisic acid receptor PYL2/0.475
3m8cEQUSteroid Delta-isomerase5.3.3.10.475
4k9yK9YFocal adhesion kinase 12.7.10.20.475
2vcmM11Isopenicillin N synthase1.21.3.10.474
3ov4EQUSteroid Delta-isomerase5.3.3.10.474
3vewADPnebramycin 5' synthase6.1.2.20.474
3zvuA8SAbscisic acid receptor PYR1/0.474
4an2EUIDual specificity mitogen-activated protein kinase kinase 12.7.12.20.474
4n6hEJ4Delta-type opioid receptor/0.474
1ci7UMPThymidylate synthase2.1.1.450.473
3fln3FNMitogen-activated protein kinase 14/0.473
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.473
2kb2FMNUncharacterized protein/0.472
4aoxFADSteroid monooxygenase/0.472
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
2j62GSZO-GlcNAcase NagJ/0.471
2xy93ESAngiotensin-converting enzyme3.2.10.471
4qa2SHHHistone deacetylase 83.5.1.980.471
1tdcUMPThymidylate synthase/0.470
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.470
3ertOHTEstrogen receptor/0.470
3k3bADPKinesin-like protein KIF11/0.470
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.470
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.469
4a51DQ8Kinesin-like protein KIF11/0.469
4jq7KJQEpidermal growth factor receptor2.7.10.10.469
1bp0UMPThymidylate synthase/0.468
1ouy094Mitogen-activated protein kinase 14/0.468
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.468
4dscA8SAbscisic acid receptor PYL3/0.468
4jr3KJREpidermal growth factor receptor2.7.10.10.468
2hiw7MPTyrosine-protein kinase ABL12.7.10.20.467
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
3tm4SAMUncharacterized protein/0.467
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.467
1k7fIAVTryptophan synthase alpha chain/0.466
1wbsLI2Mitogen-activated protein kinase 14/0.466
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.466
3ujlA8SAbscisic acid receptor PYL2/0.466
4aa5NQBMitogen-activated protein kinase 14/0.466
5c1mCLRMu-type opioid receptor/0.466
1kl2FONSerine hydroxymethyltransferase/0.465
1m9k7NINitric oxide synthase, endothelial1.14.13.390.465
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.465
2qboCAMCamphor 5-monooxygenase1.14.15.10.465
3fwfCAMCamphor 5-monooxygenase1.14.15.10.465
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
3nmnPYVAbscisic acid receptor PYL1/0.465
3rgaLSBEpoxide hydrolase LasB5.5.10.465
4cp4CAMCamphor 5-monooxygenase1.14.15.10.465
4jx1CAHCamphor 5-monooxygenase1.14.15.10.465
4ug5XFKNitric oxide synthase oxygenase1.14.13.1650.465
5d1bTSNHistone deacetylase 83.5.1.980.465
2yekEAMBromodomain-containing protein 2/0.464
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.464
4jq4IMNAldo-keto reductase family 1 member C2/0.464
4px9ADPATP-dependent RNA helicase DDX3X3.6.4.130.464
1ftlDNQGlutamate receptor 2/0.463
1y5vNE8Queuine tRNA-ribosyltransferase2.4.2.290.463
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.463
3lxiCAMCytochrome P450/0.463
3w9rA8SAbscisic acid receptor PYL9/0.463
2dkiFAD3-hydroxybenzoate 4-monooxygenase1.14.13.230.462
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.462
3c35KAIGlutamate receptor ionotropic, kainate 1/0.462
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.462
3ivgFG5Pantothenate synthetase6.3.2.10.462
3nr4PYVAbscisic acid receptor PYL2/0.462
1qvtPRLHTH-type transcriptional regulator QacR/0.461
3flq891Mitogen-activated protein kinase 14/0.461
3jwcEKBDihydrofolate reductase/0.461
4kkyCAMCamphor 5-monooxygenase1.14.15.10.461
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.460
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.460
3kdjA8SAbscisic acid receptor PYL1/0.460
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.460
4qa0SHHHistone deacetylase 83.5.1.980.460
2ohjFMNType A flavoprotein FprA10.459
2zbaZBATrichothecene 3-O-acetyltransferase/0.459
3n0tOPYDipeptidyl peptidase 23.4.14.20.459
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.459
4l4cCAMCamphor 5-monooxygenase1.14.15.10.459
1coyANDCholesterol oxidase1.1.3.60.458
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.458
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.458
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.458
3c3ySAHO-methyltransferase/0.458
3nmvPYVAbscisic acid receptor PYL2/0.458
3ojiPYVAbscisic acid receptor PYL3/0.458
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.458
3r6pA8SAbscisic acid receptor PYL10/0.458
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.458
4l8u9AZSerum albumin/0.458
4wboANWRhodopsin kinase/0.458
1fm4DXCMajor pollen allergen Bet v 1-L/0.457
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.457
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2idoTMPDNA polymerase III subunit epsilon2.7.7.70.457
2itzIREEpidermal growth factor receptor2.7.10.10.457
3h18PMSEsterase/lipase/0.457
3kdiA8SAbscisic acid receptor PYL2/0.457
3w2o03PEpidermal growth factor receptor2.7.10.10.457
4hnc0UTMandelate racemase/0.457
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.457
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.456
1k6vXN2Gag-Pol polyprotein3.4.23.160.456
1qoqIGPTryptophan synthase alpha chain/0.456
1t86CAMCamphor 5-monooxygenase1.14.15.10.456
2uxuNARHTH-type transcriptional regulator TtgR/0.456
2zazGK1Mitogen-activated protein kinase 14/0.456
3h03UBPGlutamate receptor 2/0.456
3iocA5DPantothenate synthetase6.3.2.10.456
3p99LNPLanosterol 14-alpha-demethylase/0.456
4o4eATPKinase/0.456
4x5fFOLDihydrofolate reductase1.5.1.30.456
5hg0SAMPantothenate synthetase/0.456
1k6tXN1Gag-Pol polyprotein3.4.23.160.455
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2cd8PXICytochrome P450 monooxygenase PikC/0.455
2qbmCAMCamphor 5-monooxygenase1.14.15.10.455
2qbnCAMCamphor 5-monooxygenase1.14.15.10.455
3csdEMOPutative ketoacyl reductase1.3.10.455
4cdmFADDeoxyribodipyrimidine photolyase/0.455
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.455
4klaCHDFerrochelatase, mitochondrial4.99.1.10.455
4la7A1OAbscisic acid receptor PYL2/0.455
4pdaCTNNucleoside permease/0.455
1hfqMOTDihydrofolate reductase1.5.1.30.454
1oiyN41Cyclin-dependent kinase 22.7.11.220.454
1x2hLPALipoate-protein ligase A6.3.1.200.454
2duv371Cyclin-dependent kinase 22.7.11.220.454
2ojg19AMitogen-activated protein kinase 12.7.11.240.454
2p83MR0Beta-secretase 13.4.23.460.454
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.454
3g7jGTXGlutathione transferase GST1-4/0.454
3nnxEDDMitogen-activated protein kinase 14/0.454
4at2ASDPossible succinate dehydrogenase/0.454
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1dz4CAMCamphor 5-monooxygenase1.14.15.10.453
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.453
1lhwESMSex hormone-binding globulin/0.453
1t85CAMCamphor 5-monooxygenase1.14.15.10.453
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.453
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.453
2pmnK51Protein kinase 7/0.453
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3ns2PYVAbscisic acid receptor PYL2/0.453
3qw2NADMyo-inositol-1-phosphate synthase (Ino1)/0.453
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.453
3sgy06WDihydrofolate reductase1.5.1.30.453
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.453
3vt7VDXVitamin D3 receptor/0.453
4dma0L8Estrogen receptor/0.453
4dpwAGSMevalonate diphosphate decarboxylase/0.453
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.453
4hni16WCasein kinase I isoform epsilon2.7.11.10.453
4jx1CAMCamphor 5-monooxygenase1.14.15.10.453
5cvhADPCasein kinase II subunit alpha2.7.11.10.453
5dhgDGVNociceptin receptor/0.453
4djhJDCKappa-type opioid receptor/0.453
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1eioGCHGastrotropin/0.452
1m9rINENitric oxide synthase, endothelial1.14.13.390.452
1qiwDPDCalmodulin/0.452
1t87CAMCamphor 5-monooxygenase1.14.15.10.452
2cppCAMCamphor 5-monooxygenase1.14.15.10.452
2x9dITCTetracycline repressor protein class D/0.452
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.452
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.452
3nx2FERFerulic acid decarboxylase/0.452
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.452
3swrSFGDNA (cytosine-5)-methyltransferase 12.1.1.370.452
3up3XCAaceDAF-12/0.452
3vetADPnebramycin 5' synthase6.1.2.20.452
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.452
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.452
4nmbFADBifunctional protein PutA/0.452
1im2ADPATP-dependent protease ATPase subunit HslU/0.451
1k6pXN3Gag-Pol polyprotein3.4.23.160.451
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.451
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.451
2gs7ANPEpidermal growth factor receptor2.7.10.10.451
2qblCAMCamphor 5-monooxygenase1.14.15.10.451
2r0cFADPutative FAD-monooxygenase/0.451
2vwqNAPGlucose 1-dehydrogenase/0.451
3aosJH2Hemolymph juvenile hormone binding protein/0.451
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.451
3gc9B45Mitogen-activated protein kinase 112.7.11.240.451
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.451
4bbgV02Kinesin-like protein KIF11/0.451
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ixc1JDGlucokinase2.7.1.20.451
4jhz1KVBeta-glucuronidase3.2.1.310.451
1an5CB3Thymidylate synthase/0.450
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.450
1fkxPRHAdenosine deaminase3.5.4.40.450
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.450
1m17AQ4Epidermal growth factor receptor2.7.10.10.450
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.450
1rx5DDFDihydrofolate reductase1.5.1.30.450
1th6OINBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.450
1unlRRCCyclin-dependent-like kinase 52.7.11.10.450
1zdfUPGGlycogenin-12.4.1.1860.450
2btdADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.450
2i1vADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.450
2j7t274Serine/threonine-protein kinase 102.7.11.10.450
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.450
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.450
2vd5BI8Myotonin-protein kinase2.7.11.10.450
2zaxCAMCamphor 5-monooxygenase1.14.15.10.450
2zb8IMNProstaglandin reductase 21.3.1.480.450
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3fwiCAMCamphor 5-monooxygenase1.14.15.10.450
3fwjCAMCamphor 5-monooxygenase1.14.15.10.450
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4jlk1NODeoxycytidine kinase2.7.1.740.450
4jvlESTEstrogen sulfotransferase2.8.2.40.450
4lb2DM5Serum albumin/0.450
4lg5A1OAbscisic acid receptor PYL2/0.450
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.450
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.450
1iwiCAMCamphor 5-monooxygenase1.14.15.10.449
1ot7CHCBile acid receptor/0.449
1u33LM2Pancreatic alpha-amylase/0.449
1v0pPVBCell division control protein 2 homolog2.7.11.220.449
1x1cSAHC-20 methyltransferase/0.449
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.449
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3junAJDPhenazine biosynthesis protein A/B/0.449
3njoP2MAbscisic acid receptor PYR1/0.449
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.449
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.449
4jlj1NMDeoxycytidine kinase2.7.1.740.449
4jlt8PRCytochrome P450 2B41.14.14.10.449
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.448
1hnvTBOGag-Pol polyprotein2.7.7.490.448
1j3jUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
1tl3H20Gag-Pol polyprotein2.7.7.490.448
2c7xNRBCytochrome P450 monooxygenase PikC/0.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2itpAEEEpidermal growth factor receptor2.7.10.10.448
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.448
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3mdvCL6Cholesterol 24-hydroxylase/0.448
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.448
3zrbORCProgesterone receptor/0.448
4b7sQLECytochrome P450 monooxygenase PikC/0.448
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.448
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.448
4dhyS41Glucokinase2.7.1.20.448
4el9AFERibosomal protein S6 kinase alpha-32.7.11.10.448
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.448
4pb1RBVNucleoside permease/0.448
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.447
1jumBERHTH-type transcriptional regulator QacR/0.447
1lb9DNQGlutamate receptor 2/0.447
1upw444Oxysterols receptor LXR-beta/0.447
1zhwHC2Oxysterol-binding protein homolog 4/0.447
3dmgSAHProbable ribosomal RNA small subunit methyltransferase/0.447
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.447
3nefPYVAbscisic acid receptor PYL1/0.447
3njoPYVAbscisic acid receptor PYR1/0.447
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.447
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4ejvLCLTranscriptional regulator TcaR/0.447
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.447
4jdaA9SAbscisic acid receptor PYL3/0.447
4jv3N32Beta-ketoacyl synthase/0.447
4l4fCAMCamphor 5-monooxygenase1.14.15.10.447
4pd6URINucleoside permease/0.447
4xwtU5PRibonuclease J/0.447
1fkwPURAdenosine deaminase3.5.4.40.446
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1qjgEQUSteroid Delta-isomerase5.3.3.10.446
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.446
2agvBHQSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
2g1pSAHDNA adenine methylase2.1.1.720.446
2vw5BC6ATP-dependent molecular chaperone HSP82/0.446
2wleCOAPolysialic acid O-acetyltransferase/0.446
2zulSAMProbable ribosomal RNA small subunit methyltransferase/0.446
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.446
3orn3ORDual specificity mitogen-activated protein kinase kinase 12.7.12.20.446
3uleC69Actin-related protein 3/0.446
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.446
3wrjCAMCamphor 5-monooxygenase1.14.15.10.446
3wrmCAMCamphor 5-monooxygenase1.14.15.10.446
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.446
4b99R4LMitogen-activated protein kinase 72.7.11.240.446
4c9oCAMCytochrome P450/0.446
4cf23GMIntegrase/0.446
4de50JDPantothenate synthetase6.3.2.10.446
4deg0JJHepatocyte growth factor receptor2.7.10.10.446
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.446
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.445
1rrmAPRLactaldehyde reductase1.1.1.770.445
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.445
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.445
2jedLG8Protein kinase C theta type2.7.11.130.445
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.445
2xweAMFGlucosylceramidase3.2.1.450.445
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.445
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.445
3h1vTK1Glucokinase2.7.1.20.445
3negPYVAbscisic acid receptor PYL1/0.445
3nmhPYVAbscisic acid receptor PYL2/0.445
3srsM23Dihydrofolate reductase1.5.1.30.445
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.445
4jshQ15Nitric oxide synthase, brain1.14.13.390.445
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.445
4z07PCGcGMP-dependent protein kinase 12.7.11.120.445
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.445
1dg5TOPDihydrofolate reductase1.5.1.30.444
1yy44NAEstrogen receptor beta/0.444
2rkfAB1Pol protein/0.444
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.444
3anlNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.444
3bqr4RBDeath-associated protein kinase 3/0.444
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3oafOAGDihydrofolate reductase1.5.1.30.444
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.444
3sl2ATPSensor histidine kinase WalK/0.444
4bfvZVVPantothenate kinase2.7.1.330.444
4fv8E63Mitogen-activated protein kinase 12.7.11.240.444
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4u03GTPCyclic GMP-AMP synthase/0.444
4ej4EJ4Delta-type opioid receptor/0.444
1hfpMOTDihydrofolate reductase1.5.1.30.443
1kquBR4Phospholipase A2, membrane associated/0.443
1ppjANYCytochrome b/0.443
1q3qANPThermosome subunit alpha/0.443
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.443
1zrzBI1Protein kinase C iota type2.7.11.130.443
2az3CDPNucleoside diphosphate kinase/0.443
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.443
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.443
2ittAEEEpidermal growth factor receptor2.7.10.10.443
2qxxTTPdCTP deaminase3.5.4.130.443
2y6fM9FIsopenicillin N synthase1.21.3.10.443
2zb0GK3Mitogen-activated protein kinase 14/0.443
3btjDEQHTH-type transcriptional regulator QacR/0.443
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.443
3imeBZ2Pantothenate synthetase6.3.2.10.443
3l8sBFFMitogen-activated protein kinase 14/0.443
3lfeZ84Mitogen-activated protein kinase 14/0.443
3n8nN883-dehydroquinate dehydratase4.2.1.100.443
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
3pj8404Cyclin-dependent kinase 22.7.11.220.443
3tljSAHUncharacterized protein/0.443
4aacAAVMitogen-activated protein kinase 14/0.443
4blwSAHRibosomal RNA large subunit methyltransferase J/0.443
4g1d0VKVitamin D3 receptor A/0.443
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4rtmSAMDNA adenine methylase2.1.1.720.443
1b2lNDCAlcohol dehydrogenase1.1.1.10.442
1fmjRTLRetinol dehydratase/0.442
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1iwjCAMCamphor 5-monooxygenase1.14.15.10.442
1jmhUMPThymidylate synthase/0.442
1mraAPGMandelate racemase/0.442
1tduCB3Thymidylate synthase/0.442
1v79FR7Adenosine deaminase3.5.4.40.442
2chlDKICasein kinase I isoform gamma-32.7.11.10.442
2fai459Estrogen receptor/0.442
2m56CAMCamphor 5-monooxygenase1.14.15.10.442
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.442
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.442
3bgxMEFThymidylate synthase/0.442
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.442
3e7gAT2Nitric oxide synthase, inducible1.14.13.390.442
3l63CAMCamphor 5-monooxygenase1.14.15.10.442
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.442
3q5iANPProtein kinase, putative/0.442
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3qyw6PBMitogen-activated protein kinase 12.7.11.240.442
4a84DXCMajor pollen allergen Bet v 1-A/0.442
4b7dQLECytochrome P450 monooxygenase PikC/0.442
4jvnYUGEstrogen sulfotransferase2.8.2.40.442
4l4eCAMCamphor 5-monooxygenase1.14.15.10.442
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.442
4rtjSFGDNA adenine methylase2.1.1.720.442
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1osvCHCBile acid receptor/0.441
1oz1FPHMitogen-activated protein kinase 14/0.441
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.441
1rx7FOLDihydrofolate reductase1.5.1.30.441
1tktH12Gag-Pol polyprotein2.7.7.490.441
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.441
2c6hPXICytochrome P450 monooxygenase PikC/0.441
2cig1DGDihydrofolate reductase1.5.1.30.441
2ieaTDPPyruvate dehydrogenase E1 component1.2.4.10.441
2po7CHDFerrochelatase, mitochondrial4.99.1.10.441
2q0bACPFibroblast growth factor receptor 2/0.441
2y37A54Nitric oxide synthase, inducible1.14.13.390.441
3ebf332Nitric oxide synthase, inducible1.14.13.390.441
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.441
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3p5kP5KMitogen-activated protein kinase 14/0.441
3qfsNAPNADPH--cytochrome P450 reductase/0.441
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.441
4ek1CAMCamphor 5-monooxygenase1.14.15.10.441
4fmqANPMitogen-activated protein kinase 12.7.11.240.441
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.441
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.441
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.441
4jvmXDIEstrogen sulfotransferase2.8.2.40.441
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.441
4nc3ERM5-hydroxytryptamine receptor 2B/0.441
4rtnSAHDNA adenine methylase2.1.1.720.441
4rupH97Vitamin D3 receptor A/0.441
5dhhDGWNociceptin receptor/0.441
1cqp803Integrin alpha-L/0.440
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1m8h6NINitric oxide synthase, inducible1.14.13.390.440
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1qbsDMPGag-Pol polyprotein3.4.23.160.440
1tg2H2BPhenylalanine-4-hydroxylase1.14.16.10.440
1tsvUMPThymidylate synthase/0.440
1w84L12Mitogen-activated protein kinase 14/0.440
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.440
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.440
2ca0PXICytochrome P450 monooxygenase PikC/0.440
2feuCAMCamphor 5-monooxygenase1.14.15.10.440
2gfsPQBMitogen-activated protein kinase 14/0.440
2hcdBIVVitamin D3 receptor A/0.440
2hznKINTyrosine-protein kinase ABL12.7.10.20.440
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.440
2vmyFFOSerine hydroxymethyltransferase/0.440
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.440
2zwvSAHProbable ribosomal RNA small subunit methyltransferase/0.440
2zzcNAPThioredoxin reductase 1, cytoplasmic1.8.1.90.440
3bejMUFBile acid receptor/0.440
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.440
3d83GK6Mitogen-activated protein kinase 14/0.440
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.440
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.440
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3imxB84Glucokinase2.7.1.20.440
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3nu3478Gag-Pol polyprotein3.4.23.160.440
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.440
3v1s0LHStrictosidine synthase4.3.3.20.440
3zkyWT4Isopenicillin N synthase1.21.3.10.440
4bfxZVXPantothenate kinase2.7.1.330.440
4iskUMPThymidylate synthase/0.440
4ol0GTPGTP-binding nuclear protein Ran/0.440
4ruoBIVVitamin D3 receptor A/0.440
4zcaADPKinesin-like protein KIF11/0.440
5ero210Fusicoccadiene synthase2.5.1.290.440