sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1gvr | TNL | Pentaerythritol tetranitrate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 1.000 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.705 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.624 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.556 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.546 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.533 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.502 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.499 | |
| 3kft | NAD | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.492 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.489 | |
| 1c7o | PPG | Hemolysin | / | 0.488 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.485 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.485 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.480 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.477 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.476 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.475 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.475 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.474 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.472 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.470 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.468 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.468 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.468 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.467 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.467 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.466 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.466 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.466 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.465 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.464 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.463 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.463 | |
| 3c89 | ARG_ARG_GLY_MET_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.463 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.462 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 3qw8 | CYS_ARG_GLY_CYS_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.462 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.461 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.461 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.461 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.461 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.460 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.460 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.460 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.459 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.459 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.459 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.458 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.458 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.458 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.458 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.456 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.456 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.456 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.456 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.456 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.455 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.455 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.455 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.455 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.455 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.455 | |
| 1vft | DCS | Alanine racemase | / | 0.454 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.454 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.454 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.454 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.453 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.453 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2a3c | PNX | Endochitinase B1 | 3.2.1.14 | 0.453 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.453 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.453 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.453 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.452 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.452 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.452 | |
| 1vfs | DCS | Alanine racemase | / | 0.452 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.452 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.451 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.451 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.450 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.450 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.450 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4e2z | JHZ | Methyltransferase | / | 0.450 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.450 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.449 | |
| 1wk8 | VMS | Isoleucine--tRNA ligase | 6.1.1.5 | 0.449 | |
| 3i12 | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.449 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.449 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.449 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.449 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.449 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.448 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.448 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.448 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4e2w | JHZ | Methyltransferase | / | 0.448 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.447 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.447 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.447 | |
| 3eks | CY9 | Actin-5C | / | 0.447 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.447 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.447 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.447 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.446 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.446 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.446 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.446 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.446 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.446 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.446 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.445 | |
| 2igq | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.445 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.445 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3e8x | NAP | BH1520 protein | / | 0.445 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3p5p | A3C | Taxadiene synthase | 4.2.3.17 | 0.445 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.445 | |
| 4lut | DCS | Alanine racemase | / | 0.445 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.445 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.444 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.444 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.444 | |
| 2zr9 | DTP | Protein RecA | / | 0.444 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.444 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.444 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.443 | |
| 2o3u | NGD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.443 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.443 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.443 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.443 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.443 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.443 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.443 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.443 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.442 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.442 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.442 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.442 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3abx | RCB | Glucanase | / | 0.442 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.442 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.442 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.441 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.441 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.441 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.441 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.441 | |
| 3e6e | DCS | Alanine racemase | / | 0.441 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.441 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.441 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.441 | |
| 4jic | FMN | GTN Reductase | / | 0.441 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.441 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.441 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.441 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.440 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.440 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 2b4d | COA | Diamine acetyltransferase 1 | / | 0.440 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.440 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.440 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.440 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 | |
| 3n0c | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.440 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.440 | |
| 3v2u | ATP | Protein GAL3 | / | 0.440 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.440 |