sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3vjl | W94 | Dipeptidyl peptidase 4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 1.000 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.767 | |
| 3ccb | B2Y | Dipeptidyl peptidase 4 | / | 0.653 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.636 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.620 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.548 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.545 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.526 | |
| 4ffw | 715 | Dipeptidyl peptidase 4 | / | 0.525 | |
| 4a5s | N7F | Dipeptidyl peptidase 4 | / | 0.522 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.512 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.503 | |
| 2rgu | 356 | Dipeptidyl peptidase 4 | / | 0.502 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.500 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.496 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.491 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.490 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.489 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.487 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.487 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.485 | |
| 2oae | AIL | Dipeptidyl peptidase 4 | / | 0.484 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.480 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.480 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.480 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.479 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.478 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.476 | |
| 3g0d | XIH | Dipeptidyl peptidase 4 | / | 0.476 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.476 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.475 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.473 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.473 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.473 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.472 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.472 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.469 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.469 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.469 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.469 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.468 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.468 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.467 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.467 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.467 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.466 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.466 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.466 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.466 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.465 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.465 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.464 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.464 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.464 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.463 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.463 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.462 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.462 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.462 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.461 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.461 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.460 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.460 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.460 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.460 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.460 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.460 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.460 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.460 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.460 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.460 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.459 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.458 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.458 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.458 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.458 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.458 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.457 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.457 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.457 | |
| 3c8a | ARG_ARG_GLY_LEU_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.457 | |
| 4g1f | 0WG | Dipeptidyl peptidase 4 | / | 0.457 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.457 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.456 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.456 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.456 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.456 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 3wwm | ADP | [LysW]-aminoadipate kinase | / | 0.455 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.455 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.455 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.454 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.454 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.454 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.453 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.453 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.453 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.453 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.453 | |
| 3irh | DTP | HD domain protein | / | 0.452 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.452 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.452 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.452 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.452 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.451 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.451 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.451 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.451 | |
| 4e2d | FMN | Dehydrogenase | / | 0.451 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.450 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.450 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.450 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.450 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.450 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4jb1 | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.450 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.449 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.449 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.449 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.448 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.448 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.447 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1jil | 485 | Tyrosine--tRNA ligase | / | 0.447 | |
| 1zp4 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.447 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.447 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.447 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.447 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.447 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.447 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.447 | |
| 4ywj | NAD | 4-hydroxy-tetrahydrodipicolinate reductase | / | 0.447 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.447 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.446 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.446 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.446 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.446 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.446 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.446 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.446 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.446 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.446 | |
| 4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.446 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.445 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.445 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.445 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.445 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.445 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.444 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.444 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.444 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.444 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.444 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.444 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.444 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3pz4 | 3PZ | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.444 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.443 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.443 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.443 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.443 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.443 | |
| 4j7h | TRH | PCZA361.3 | / | 0.443 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.443 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 2ad5 | ADP | CTP synthase | / | 0.442 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.442 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.442 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.442 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.442 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 1j0d | 5PA | 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.441 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.441 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.441 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.441 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.441 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.441 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.441 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.441 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.441 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.440 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.440 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.440 | |
| 3e6e | DCS | Alanine racemase | / | 0.440 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.440 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.440 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4f3x | NAD | Putative aldehyde dehydrogenase | / | 0.440 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.440 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.440 |