sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1xnz | FCD | Methionine aminopeptidase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1xnz | FCD | Methionine aminopeptidase | / | 1.000 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.767 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.752 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.728 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.714 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.701 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.653 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.641 | |
| 2q93 | B21 | Methionine aminopeptidase | / | 0.626 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.625 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.615 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.605 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.604 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.595 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.589 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.587 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.587 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.584 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.578 | |
| 4iku | SHX | Methionine aminopeptidase 1 | / | 0.568 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.557 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.552 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.550 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.545 | |
| 2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.544 | |
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 0.544 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.542 | |
| 4fli | Y16 | Methionine aminopeptidase 1 | / | 0.539 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.538 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.538 | |
| 4hxx | 1AY | Methionine aminopeptidase 1 | / | 0.533 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.532 | |
| 3pkc | Y08 | Methionine aminopeptidase 2 | / | 0.532 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.526 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.525 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.523 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.520 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.520 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.520 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.518 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.516 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.516 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.514 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.512 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.507 | |
| 4ikr | PVP | Methionine aminopeptidase 1 | / | 0.507 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.506 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.506 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.505 | |
| 2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.503 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.502 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.502 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.499 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.499 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.498 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.497 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.497 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.497 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.494 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.494 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.491 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.490 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.489 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.482 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.482 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.481 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.481 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.474 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.473 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2gms | P0P | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.473 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.471 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.470 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.469 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.469 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.467 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.466 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 1e6z | NGO | Chitinase | / | 0.465 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.465 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.465 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.464 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.463 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.463 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 1e2l | TMC | Thymidine kinase | / | 0.462 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.462 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.460 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.459 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.459 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.459 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.457 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.457 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.457 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.457 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.457 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4q7f | 3D1 | Uncharacterized protein | / | 0.456 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.455 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.455 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.455 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.455 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.455 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.454 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.454 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.453 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.453 | |
| 4cb4 | MGT | Polymerase basic protein 2 | / | 0.453 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.453 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.453 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.453 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.452 | |
| 3ccb | B2Y | Dipeptidyl peptidase 4 | / | 0.452 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.452 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.452 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.451 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.451 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.451 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.451 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.451 | |
| 5ief | NBV | Neutral alpha-glucosidase AB | 3.2.1.84 | 0.451 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.450 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.450 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.450 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.450 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.450 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.450 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.450 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.449 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.449 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.448 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 1e2n | RCA | Thymidine kinase | / | 0.446 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.446 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.446 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.446 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.446 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.446 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4ld2 | CTN | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.445 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 1h6a | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.444 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.444 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.444 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.444 | |
| 1fwy | UD1 | Bifunctional protein GlmU | / | 0.443 | |
| 1u08 | PLP | Methionine aminotransferase | / | 0.443 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.443 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.443 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.442 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.442 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.442 | |
| 2v19 | FMN | Dodecin | / | 0.442 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.442 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.442 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.442 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.442 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.441 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.441 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.440 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.440 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.440 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.440 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.440 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.440 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.440 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 |