sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1w88 | TDP | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1w88 | TDP | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 1.000 | |
| 1w88 | TDP | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 1.000 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.515 | |
| 1dnp | MHF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.504 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.502 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.500 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.499 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.492 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.489 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.489 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.487 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.486 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.482 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.482 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.482 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.482 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.481 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.480 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.480 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.480 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.480 | |
| 2pda | TPP | Pyruvate synthase | / | 0.477 | |
| 1dfo | PLG | Serine hydroxymethyltransferase | 2.1.2.1 | 0.476 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.476 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.475 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.475 | |
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 0.474 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.474 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 1ltz | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.473 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.472 | |
| 2ada | HPR | Adenosine deaminase | 3.5.4.4 | 0.472 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.472 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.472 | |
| 1til | ATP | Anti-sigma F factor | / | 0.471 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.470 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.470 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.468 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3ddc | GNP | GTPase HRas | / | 0.467 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.466 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.466 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.466 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.466 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.463 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.463 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.463 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.463 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.462 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.462 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.462 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.462 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.462 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.461 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.461 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.460 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.459 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.459 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.459 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.459 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.459 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.459 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.459 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.458 | |
| 2trs | PLS | Tryptophan synthase beta chain | 4.2.1.20 | 0.458 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.458 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.458 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.458 | |
| 3v2u | ATP | Protein GAL3 | / | 0.458 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.458 | |
| 5epe | SAH | Uncharacterized protein | / | 0.458 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.457 | |
| 1tox | NAD | Diphtheria toxin | / | 0.457 | |
| 2xxv | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.457 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.457 | |
| 3lbh | GNP | GTPase HRas | / | 0.457 | |
| 4ubf | ADP | Kinesin-like protein KIF2C | / | 0.457 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.456 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.455 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.455 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.455 | |
| 1wnz | 2VA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.455 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.455 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.455 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.454 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.454 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.454 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.454 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.453 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.453 | |
| 1tys | DHF | Thymidylate synthase | / | 0.453 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.453 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.453 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.453 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.452 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.452 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.452 | |
| 2qe2 | 452 | Polyprotein | / | 0.452 | |
| 3ou7 | SAM | SAM-dependent methyltransferase | / | 0.452 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.451 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.451 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.451 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.451 | |
| 2zsc | BTN | Tamavidin2 | / | 0.451 | |
| 3pft | FMN | Flavin reductase | / | 0.451 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
| 4j21 | AJ6 | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.451 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.451 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1swn | BTN | Streptavidin | / | 0.450 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.450 | |
| 3lmh | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.450 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.450 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1z4u | PH9 | Polyprotein | / | 0.449 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.449 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.448 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2g0l | FLN | Neocarzinostatin | / | 0.447 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.447 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.447 | |
| 3ewd | MCF | Adenosine deaminase, putative | / | 0.447 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1r2j | FAD | FkbI | / | 0.446 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.446 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.446 | |
| 3q5p | TAC | Multidrug-efflux transporter 1 regulator | / | 0.446 | |
| 3rs4 | GNP | GTPase HRas | / | 0.446 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4kwc | SAH | Methyltransferase domain family | / | 0.446 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.445 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.445 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.445 | |
| 2clh | F19 | Tryptophan synthase alpha chain | / | 0.445 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 3oiw | GNP | GTPase HRas | / | 0.445 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.445 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.445 | |
| 4mk7 | 28O | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.444 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 4dlv | GNP | GTPase HRas | / | 0.444 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4l33 | F70 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.444 | |
| 4zob | LGC | Lin1840 protein | / | 0.444 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.443 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.443 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.443 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.443 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.442 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.442 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.442 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.442 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2p4s | DIH | AGAP005945-PA | / | 0.442 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.442 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 4a39 | GEM | Uncharacterized protein | / | 0.442 | |
| 4fwn | AQP | Propionate kinase | / | 0.442 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.442 | |
| 4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.441 | |
| 1efz | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 2c5l | GTP | GTPase HRas | / | 0.441 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.441 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2uz2 | BTN | Avd protein | / | 0.441 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.441 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.441 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.441 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.441 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.440 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.440 | |
| 1stp | BTN | Streptavidin | / | 0.440 | |
| 1ulb | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2ibu | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.440 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.440 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 |