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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1m9aGTXGlutathione S-transferase class-mu 26 kDa isozyme2.5.1.18

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1m9aGTXGlutathione S-transferase class-mu 26 kDa isozyme2.5.1.181.000
1h6aNDPGlucose--fructose oxidoreductase1.1.99.280.501
1s3uTQDDihydrofolate reductase1.5.1.30.501
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.495
1pd9CO4Dihydrofolate reductase1.5.1.30.493
2gmvPEPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.493
1kevNDPNADP-dependent isopropanol dehydrogenase1.1.1.800.488
3vrwYS5Vitamin D3 receptor/0.488
2gv8NDPThiol-specific monooxygenase1.14.130.485
1h6dNDPGlucose--fructose oxidoreductase1.1.99.280.484
1pr9NAPL-xylulose reductase1.1.1.100.482
3bg7FADPyranose 2-oxidase/0.481
3bgxTMPThymidylate synthase/0.481
2fznFADBifunctional protein PutA1.5.5.20.478
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.478
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.478
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.477
2harOCCVitamin D3 receptor/0.477
5jscFADPutative acyl-CoA dehydrogenase/0.477
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.476
4phlPILPhosphodiesterase/0.475
2j5xGSPADP-ribosylation factor 6/0.474
3wczNAPAldo-keto reductase AKR2E4/0.474
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.473
3bgxMEFThymidylate synthase/0.473
3h3qH13Collagen type IV alpha-3-binding protein/0.473
3vt5YI2Vitamin D3 receptor/0.473
4g1y0VOVitamin D3 receptor A/0.473
4nxxGDPMitochondrial dynamics protein MID51/0.473
1ie9VDXVitamin D3 receptor/0.472
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.472
1db1VDXVitamin D3 receptor/0.471
1ie8KH1Vitamin D3 receptor/0.471
2hdjNDPAldo-keto reductase family 1 member C2/0.471
3r96ACOMccE protein/0.471
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.471
3vt65YIVitamin D3 receptor/0.471
4jc51K5Stimulator of interferon genes protein/0.471
2rhgIGPTryptophan synthase alpha chain/0.470
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.470
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
4fhi0S4Vitamin D3 receptor A/0.470
5e7oMGDDMSO reductase family type II enzyme, molybdopterin subunit/0.470
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.469
4a99FADTetX family tetracycline inactivation enzyme/0.469
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.468
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.468
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.468
3ixp834Ecdysone receptor/0.468
3k4nFADPyranose 2-oxidase/0.468
1bk0ACVIsopenicillin N synthase1.21.3.10.467
1v0jFADUDP-galactopyranose mutase5.4.99.90.467
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.467
2y5s78HDihydropteroate synthase/0.467
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.467
3fql79ZGenome polyprotein2.7.7.480.467
3h3r14HCollagen type IV alpha-3-binding protein/0.467
3qt62P0Mevalonate diphosphate decarboxylase/0.467
5a3cNADSIR2 family protein/0.467
4zj8SUVOrexin receptor type 1/0.467
1mvsDTMDihydrofolate reductase1.5.1.30.466
1ryeNDPGlucose--fructose oxidoreductase1.1.99.280.466
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.466
3f1kNAPUncharacterized oxidoreductase YciK10.466
3p8z36AGenome polyprotein2.1.1.560.466
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.466
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.466
1bsvNDPGDP-L-fucose synthase/0.465
1cf3FADGlucose oxidase1.1.3.40.465
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.465
1j49NADD-lactate dehydrogenase1.1.1.280.465
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.465
2hb7O1CVitamin D3 receptor/0.465
2zl9VDAVitamin D3 receptor/0.465
3atzFMNProstaglandin F2a synthase/0.465
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.465
1szgFNSCytochrome b2, mitochondrial1.1.2.30.464
2o7pNAPRiboflavin biosynthesis protein RibD/0.464
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.464
2y05NAPProstaglandin reductase 1/0.464
3ekuCY9Actin-5C/0.464
3vrtYS2Vitamin D3 receptor/0.464
4dpwAGSMevalonate diphosphate decarboxylase/0.464
4ruoBIVVitamin D3 receptor A/0.464
1rk3VDXVitamin D3 receptor/0.463
2b3dFADModulator of drug activity B/0.463
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.463
3h3t16HCollagen type IV alpha-3-binding protein/0.463
3w0aDS5Vitamin D3 receptor/0.463
3w0gW07Vitamin D3 receptor/0.463
4e5yNDPGDP-L-fucose synthase1.1.1.2710.463
4el5D1MGlycogen phosphorylase, muscle form2.4.1.10.463
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.463
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4lcjNADC-terminal-binding protein 2/0.463
4udrFAD5-(hydroxymethyl)furfural oxidase/0.463
1hb1OCVIsopenicillin N synthase1.21.3.10.462
1osvCHCBile acid receptor/0.462
1rydNDPGlucose--fructose oxidoreductase1.1.99.280.462
2dteNAIGlucose 1-dehydrogenase related protein/0.462
2hk9NAPShikimate dehydrogenase (NADP(+))/0.462
2iviACWIsopenicillin N synthase1.21.3.10.462
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
4nh82LCHeat shock protein HSP 90-alpha/0.462
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.461
1njfAGSDNA polymerase III subunit tau2.7.7.70.461
1tj2FADBifunctional protein PutA1.5.5.20.461
2g78REACellular retinoic acid-binding protein 2/0.461
4iae1DXAlr2278 protein/0.461
4mihFADPyranose 2-oxidase1.1.3.100.461
4z26FADPutative GMC-type oxidoreductase R13510.461
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.461
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.460
1qjfACSIsopenicillin N synthase1.21.3.10.460
2ok7FADFerredoxin--NADP reductase, apicoplast/0.460
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.460
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.459
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.459
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.459
1h50FMNPentaerythritol tetranitrate reductase/0.459
1txiTX5Vitamin D3 receptor/0.459
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.459
3t3r9PLCytochrome P450 2A61.14.130.459
4itfTFYVitamin D3 receptor/0.459
4yqfGDPSeptin-9/0.459
1cbqRE9Cellular retinoic acid-binding protein 2/0.458
1n5dNDPCarbonyl reductase [NADPH] 1/0.458
1nytNAPShikimate dehydrogenase (NADP(+))/0.458
1t88CAMCamphor 5-monooxygenase1.14.15.10.458
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.458
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.458
1evjNADGlucose--fructose oxidoreductase1.1.99.280.457
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.457
2znq401Peroxisome proliferator-activated receptor delta/0.457
3dr1C5DVitamin D3 receptor A/0.457
3s1dZIRCytokinin dehydrogenase 11.5.99.120.457
3vtbTKAVitamin D3 receptor/0.457
3zoiM2WIsopenicillin N synthase1.21.3.10.457
3zuyTCHTransporter/0.457
4f4qFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.457
4l1xNAPAldo-keto reductase family 1 member C2/0.457
1ipeNDPTropinone reductase 21.1.1.2360.456
1s0zEB1Vitamin D3 receptor/0.456
1t2aNDPGDP-mannose 4,6 dehydratase4.2.1.470.456
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.456
2hc4VDXVitamin D3 receptor A/0.456
2zsaADPPantothenate kinase2.7.1.330.456
3b2sB2STrichothecene 3-O-acetyltransferase/0.456
3b70NAPEnoyl reductase LovC10.456
3h3sH15Collagen type IV alpha-3-binding protein/0.456
3own3OWRenin3.4.23.150.456
3up0D7SaceDAF-12/0.456
4g1d0VKVitamin D3 receptor A/0.456
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.456
4h4yNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.456
4l4fCAMCamphor 5-monooxygenase1.14.15.10.456
4z24FADPutative GMC-type oxidoreductase R13510.456
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.455
1rfuADPPyridoxal kinase2.7.1.350.455
1wntNAPL-xylulose reductase1.1.1.100.455
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.455
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.455
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.455
2r8fAGSNon-structural protein 23.6.40.455
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.455
3nf4FADAcyl-CoA dehydrogenase domain-containing protein/0.455
3zeiAWHO-acetylserine sulfhydrylase/0.455
4l4xNDPAmphI/0.455
4uirFADOleate hydratase4.2.1.530.455
1ia1NDPDihydrofolate reductase1.5.1.30.454
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.454
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.454
2bl4NADLactaldehyde reductase1.1.1.770.454
2h3wCOACarnitine O-acetyltransferase2.3.1.70.454
2j83BATUlilysin3.4.240.454
2vbpVB1Isopenicillin N synthase1.21.3.10.454
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.454
4ia3BIVVitamin D3 receptor A/0.454
1a59COA2-methylcitrate synthase/0.453
1dyhDZFDihydrofolate reductase1.5.1.30.453
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.453
1w6hTITPlasmepsin-23.4.23.390.453
2b8l5HABeta-secretase 13.4.23.460.453
2ozuACOHistone acetyltransferase KAT6A/0.453
2po7CHDFerrochelatase, mitochondrial4.99.1.10.453
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.453
3e2sFADBifunctional protein PutA1.5.5.20.453
3gqvNAPEnoyl reductase LovC10.453
3kpzZNEVitamin D3 receptor/0.453
3lqfNADGalactitol dehydrogenase/0.453
3vydVYDRenin3.4.23.150.453
3w0yDS4Vitamin D3 receptor/0.453
3wrmCAMCamphor 5-monooxygenase1.14.15.10.453
4a6bQG8Gag-Pol polyprotein3.4.23.160.453
4g20484Vitamin D3 receptor A/0.453
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
4hxyNDPPlm1/0.453
4hy6FJ1Heat shock protein HSP 90-alpha/0.453
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4nxuADPMitochondrial dynamics protein MID51/0.453
1mp0NADAlcohol dehydrogenase class-31.1.1.10.452
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.452
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.452
1tj0FADBifunctional protein PutA1.5.5.20.452
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.452
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.452
2pg0FADAcyl-CoA dehydrogenase/0.452
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2xlrFADPutative flavin-containing monooxygenase/0.452
2xpuTDCTetracycline repressor protein class D/0.452
3gwdFADCyclohexanone monooxygenase/0.452
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.452
3sx2NADUncharacterized protein/0.452
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4rvnCOAPhenylacetate-coenzyme A ligase/0.452
1dyjDDFDihydrofolate reductase1.5.1.30.451
1fwkADPHomoserine kinase2.7.1.390.451
1kfbIGPTryptophan synthase alpha chain/0.451
1kkq471Peroxisome proliferator-activated receptor alpha/0.451
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.451
2ahrNAPPyrroline-5-carboxylate reductase/0.451
2dvlFADAcyl-CoA dehydrogenase/0.451
2hb8MVDVitamin D3 receptor/0.451
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.451
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.451
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.451
2ywlFADThioredoxin reductase related protein/0.451
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3p74FMNPentaerythritol tetranitrate reductase/0.451
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.451
4a81DXCMajor pollen allergen Bet v 1-A/0.451
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.451
4l4eCAMCamphor 5-monooxygenase1.14.15.10.451
4ryvZEAProtein LlR18A/0.451
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.451
1cbsREACellular retinoic acid-binding protein 2/0.450
1h74AGSHomoserine kinase2.7.1.390.450
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.450
2a1nCAMCamphor 5-monooxygenase1.14.15.10.450
2fhnBNIAvidin-related protein 4/5/0.450
2givACOHistone acetyltransferase KAT8/0.450
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.450
2hamC33Vitamin D3 receptor/0.450
2hpvFMNFMN-dependent NADH-azoreductase1.70.450
2yy8MTAtRNA (cytidine(56)-2'-O)-methyltransferase/0.450
3b6zCO7Enoyl reductase LovC10.450
3och2MXDihydrofolate reductase1.5.1.30.450
3q8uADPNucleoside diphosphate kinase/0.450
3w0jT08Vitamin D3 receptor/0.450
4do30LAFatty-acid amide hydrolase 13.5.1.990.450
4e5kNADPhosphonate dehydrogenase1.20.1.10.450
4pnmNU1Tankyrase-22.4.2.300.450
4rquNADAlcohol dehydrogenase class-P/0.450
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.450
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.450
1diuBDMDihydrofolate reductase1.5.1.30.449
1h6bNDPGlucose--fructose oxidoreductase1.1.99.280.449
1okkGCPSignal recognition particle protein/0.449
1okkGCPSignal recognition particle receptor FtsY/0.449
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.449
1tysDHFThymidylate synthase/0.449
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.449
1xagNAD3-dehydroquinate synthase/0.449
2bxoOPBSerum albumin/0.449
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.449
2jahNDPClavaldehyde dehydrogenase/0.449
3bk2U5PRibonuclease J/0.449
3m0oFADMonomeric sarcosine oxidase1.5.3.10.449
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.449
3vyfVYFRenin3.4.23.150.449
3w5rLOAVitamin D3 receptor/0.449
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.449
4g1z0VPVitamin D3 receptor A/0.449
4iteTEYVitamin D3 receptor/0.449
4jicFMNGTN Reductase/0.449
4jqh1MFAlr2278 protein/0.449
4ng5PFBAlcohol dehydrogenase E chain1.1.1.10.449
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.449
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
1bdmNAXMalate dehydrogenase/0.448
1i2bNADUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.448
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1pq944BOxysterols receptor LXR-beta/0.448
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.448
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.448
1s19MC9Vitamin D3 receptor/0.448
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.448
2i7pACOPantothenate kinase 32.7.1.330.448
2igoFADPyranose 2-oxidase/0.448
2w3bNDPDihydrofolate reductase1.5.1.30.448
3drcMTXDihydrofolate reductase1.5.1.30.448
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3rj9NADAlcohol dehydrogenase1.1.1.10.448
3vt45YIVitamin D3 receptor/0.448
3vt8YI3Vitamin D3 receptor/0.448
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.448
3w0iO11Vitamin D3 receptor/0.448
4jtqNAPAldo-keto reductase family 1 member C2/0.448
4m9aFDAAcyl-CoA dehydrogenase/0.448
4o8aFADBifunctional protein PutA1.2.1.880.448
4qecNAPElxO/0.448
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.448
1dhfFOLDihydrofolate reductase1.5.1.30.447
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.447
1m78NDPDihydrofolate reductase1.5.1.30.447
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.447
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.447
1x1cSAHC-20 methyltransferase/0.447
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.447
2gs7ANPEpidermal growth factor receptor2.7.10.10.447
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.447
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
3gwfNAPCyclohexanone monooxygenase/0.447
3r5yF42Uncharacterized protein/0.447
4d04NAPPhenylacetone monooxygenase1.14.13.920.447
4i02CMPcAMP-activated global transcriptional regulator CRP/0.447
4ia7BIVVitamin D3 receptor A/0.447
4krs1SXTankyrase-12.4.2.300.447
4q71FADBifunctional protein PutA/0.447
4tuvCPZCytochrome P450 1191.140.447
5dbvCOAAldehyde Dehydrogenase/0.447
1dr5NAPDihydrofolate reductase1.5.1.30.446
1draMTXDihydrofolate reductase1.5.1.30.446
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1g6kNADGlucose 1-dehydrogenase1.1.1.470.446
1h65GDPTranslocase of chloroplast 343.6.50.446
1heuNADAlcohol dehydrogenase E chain1.1.1.10.446
1pw1HELD-alanyl-D-alanine carboxypeptidase3.4.16.40.446
1x8lOXRRetinol dehydratase/0.446
2is0I03Beta-secretase 13.4.23.460.446
2v16C47Renin3.4.23.150.446
3eluSAMMethyltransferase/0.446
3h7rNAPAldo-keto reductase family 4 member C8/0.446
3pm9FADPutative oxidoreductase/0.446
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.446
3vt3VDXVitamin D3 receptor/0.446
3wthIM4Acetylcholine-binding protein/0.446
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.446
4g95OAGDihydrofolate reductase1.5.1.30.446
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.446
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.446
4rupH97Vitamin D3 receptor A/0.446
4yaiNAIC alpha-dehydrogenase/0.446
5ftfADPTPR domain protein/0.446
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
1ja0FADNADPH--cytochrome P450 reductase/0.445
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.445
1mjaCOAHistone acetyltransferase ESA1/0.445
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.445
1r8bATPCCA-adding enzyme2.7.7.720.445
1rf7DHFDihydrofolate reductase1.5.1.30.445
1rkhVD2Vitamin D3 receptor/0.445
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.445
2ntrL00Beta-secretase 13.4.23.460.445
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.445
2xviFADPutative flavin-containing monooxygenase/0.445
3b20NADGlyceraldehyde-3-phosphate dehydrogenase/0.445
3cobADPKinesin heavy chain-like protein/0.445
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
3mj4URMUDP-galactopyranose mutase/0.445
3pndFADFAD:protein FMN transferase/0.445
3s3vTOPDihydrofolate reductase1.5.1.30.445
3to6LYS_CMCHistone acetyltransferase ESA1/0.445
3wrlCAMCamphor 5-monooxygenase1.14.15.10.445
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.445
4k9nTZDBenzoylformate decarboxylase4.1.1.70.445
4o7uTHFThymidylate synthase/0.445
5itzLOCTubulin beta-2B chain/0.445
1hetNADAlcohol dehydrogenase E chain1.1.1.10.444
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.444
1jq5NADGlycerol dehydrogenase1.1.1.60.444
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.444
1n7hNDPGDP-mannose 4,6 dehydratase 24.2.1.470.444
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.444
1rneC60Renin3.4.23.150.444
1u4oNDDL-lactate dehydrogenase1.1.1.270.444
2c12FADNitroalkane oxidase1.7.3.10.444
2c29NAPDihydroflavonol 4-reductase/0.444
2cwfNDPDelta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase/0.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
2qo9ANPEphrin type-A receptor 32.7.10.10.444
2rghFADAlpha-Glycerophosphate Oxidase/0.444
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.444
3dmeFADPutative conserved exported protein/0.444
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.444
3o26NDPSalutaridine reductase/0.444
3toxNAPPutative oxidoreductase/0.444
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
4b67FADL-ornithine N(5)-monooxygenase/0.444
4ehyADPTetraacyldisaccharide 4'-kinase/0.444
4k42ADPActin, alpha skeletal muscle/0.444
4x4lNAIRetinal dehydrogenase 11.2.1.360.444
4xo7NAPAldo-keto reductase family 1 member C2/0.444
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.444
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.443
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.443
1snyNAPLD36273p/0.443
1upw444Oxysterols receptor LXR-beta/0.443
1v4sMRKGlucokinase2.7.1.20.443
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2g8yNADHydroxycarboxylate dehydrogenase B/0.443
2ifaFMNUncharacterized protein/0.443
2rc4ACOHistone acetyltransferase KAT6A/0.443
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.443
3d91REMRenin3.4.23.150.443
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3mnrSD1Heat shock protein HSP 90-alpha/0.443
3ohh3HHBeta-secretase 13.4.23.460.443
3ql6NIMLactoperoxidase1.11.1.70.443
3s79ASDAromatase1.14.14.140.443
4a6rTA8Probable aminotransferase/0.443
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.443
4fn4NADShort chain dehydrogenase/0.443
4xq9NADHomospermidine synthase2.5.1.440.443
8dfrNDPDihydrofolate reductase1.5.1.30.443
1bil0IURenin3.4.23.150.442
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.442
1qoqIGPTryptophan synthase alpha chain/0.442
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.442
1x7hNDPPutative ketoacyl reductase1.3.10.442
2gsdNADFormate dehydrogenase/0.442
2nvbNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.442
2q9fC3SCholesterol 24-hydroxylase/0.442
2wf1ZY1Beta-secretase 13.4.23.460.442
3cifNADGlyceraldehyde-3-phosphate dehydrogenase/0.442
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3fnlSHALactoperoxidase/0.442
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3in6FMNUncharacterized protein/0.442
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
3slz3TLPutative gag-pro-pol polyprotein/0.442
3t1tGDPProbable gliding protein mglA/0.442
3tvuB37Acetyl-CoA carboxylase/0.442
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.442
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.442
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.442
1b8uNADMalate dehydrogenase/0.441
1bxsNADRetinal dehydrogenase 11.2.1.360.441
1d0mBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.441
1dz4CAMCamphor 5-monooxygenase1.14.15.10.441
1getFADGlutathione reductase1.8.1.70.441
1nvtNAPShikimate dehydrogenase (NADP(+))/0.441
1qmzATPCyclin-dependent kinase 22.7.11.220.441
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.441
1ygkRRCPyridoxal kinase2.7.1.350.441
2dw4FADLysine-specific histone demethylase 1A10.441
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.441
2hasC3OVitamin D3 receptor/0.441
2tpsTPSThiamine-phosphate synthase/0.441
2v59LZKBiotin carboxylase6.3.4.140.441
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.441
2zlaVDBVitamin D3 receptor/0.441
2zxuDSTtRNA dimethylallyltransferase2.5.1.750.441
3bbrBHYGlutamate receptor 2/0.441
3ingNDPHomoserine dehydrogenase related protein/0.441
3oqfS51Renin3.4.23.150.441
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.441
3vt9YI4Vitamin D3 receptor/0.441
3w8eNAD3-hydroxybutyrate dehydrogenase/0.441
4dz5NAPAldo-keto reductase family 1 member C3/0.441
4fidGDPG protein alpha subunit, putative/0.441
4gid0GHBeta-secretase 13.4.23.460.441
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.441
4n3r2GUTankyrase-12.4.2.300.441
4q72FADBifunctional protein PutA/0.441
4x28FDAAcyl-CoA dehydrogenase FadE26/0.441
4x28FDAAcyl-CoA dehydrogenase FadE27/0.441
4x5hFOLDihydrofolate reductase1.5.1.30.441
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.441
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.441
1c1dNAIPhenylalanine dehydrogenase/0.440
1e3eNAIAlcohol dehydrogenase 41.1.1.10.440
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.440
1kvrNADUDP-glucose 4-epimerase5.1.3.20.440
1ppjANYCytochrome b/0.440
1rj9GCPSignal recognition particle receptor FtsY/0.440
1tllFMNNitric oxide synthase, brain1.14.13.390.440
1uamSAHtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.440
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.440
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.440
2ejzSAHDiphthine synthase/0.440
2ftoCB3Thymidylate synthase/0.440
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.440
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.440
2vbdV10Isopenicillin N synthase1.21.3.10.440
2wf3ZY3Beta-secretase 13.4.23.460.440
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.440
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.440
2zuiCAMCamphor 5-monooxygenase1.14.15.10.440
3bw4FMNPutative 2-nitropropane dioxygenase/0.440
3ihgVAKAklavinone 12-hydroxylase RdmE/0.440
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.440
3p62FMNPentaerythritol tetranitrate reductase/0.440
4a6nFADTetX family tetracycline inactivation enzyme/0.440
4b8zNAPGDP-L-fucose synthase1.1.1.2710.440
4dc0NDPPutative ketoacyl reductase1.3.10.440
4du82P0Mevalonate diphosphate decarboxylase/0.440
4e2bFMNDehydrogenase/0.440
4irnFADAnaB/0.440
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.440
4l8u9AZSerum albumin/0.440
4n6hEJ4Delta-type opioid receptor/0.440
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.440
5eccNAPDehydrofolate reductase type I/0.440