sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4rf9 | AGS | Arginine kinase | 2.7.3.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4rf9 | AGS | Arginine kinase | 2.7.3.3 | 1.000 | |
| 3vnh | FUU | Kelch-like ECH-associated protein 1 | / | 0.524 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.516 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.516 | |
| 3jq3 | ADP | Lombricine kinase | / | 0.510 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.499 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.495 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.495 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.493 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.493 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.493 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.492 | |
| 3tdw | GDP | Gentamicin resistance protein | / | 0.491 | |
| 1i2c | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.489 | |
| 1sb8 | UD2 | WbpP | / | 0.489 | |
| 5eom | CTP | Putative nucleotidyltransferase MAB21L1 | / | 0.489 | |
| 4xhg | ADP | Uncharacterized protein | / | 0.487 | |
| 3lu8 | IQX | Serum albumin | / | 0.486 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.485 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.484 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.484 | |
| 4zas | TYD | CalS13 | / | 0.484 | |
| 1hk2 | T44 | Serum albumin | / | 0.483 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.483 | |
| 1xjq | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.482 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 1ho5 | ADN | Protein UshA | 3.1.3.5 | 0.480 | |
| 1mjh | ATP | Universal stress protein MJ0577 | / | 0.480 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.480 | |
| 1ny5 | ADP | Transcriptional regulator (NtrC family) | / | 0.479 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.479 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.478 | |
| 2lbv | EB4 | Extracellular fatty acid-binding protein | / | 0.477 | |
| 2vqd | AP2 | Biotin carboxylase | 6.3.4.14 | 0.477 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.477 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.476 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.475 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.475 | |
| 4zwg | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.475 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.474 | |
| 3umo | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.474 | |
| 2wu1 | FGS | Glucosamine-6-phosphate deaminase | 3.5.99.6 | 0.473 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.473 | |
| 3d45 | GDP | Poly(A)-specific ribonuclease PARN | 3.1.13.4 | 0.473 | |
| 4iqk | IQK | Kelch-like ECH-associated protein 1 | / | 0.473 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.472 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.472 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.472 | |
| 2xzw | ATP | Nitrogen regulatory protein P-II | / | 0.472 | |
| 3hf3 | FMN | Chromate reductase | / | 0.472 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.472 | |
| 5eso | ISC | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.472 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.471 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.471 | |
| 1a5u | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.470 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.470 | |
| 3spt | UD1 | Bifunctional protein GlmU | / | 0.470 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.470 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.470 | |
| 4xb1 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.470 | |
| 2fyp | RDE | Endoplasmin | / | 0.469 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.469 | |
| 3npc | B96 | Mitogen-activated protein kinase 9 | 2.7.11.24 | 0.469 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.469 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.469 | |
| 4o4i | ACP | Tubulin tyrosine ligase | / | 0.469 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.469 | |
| 2pml | ANP | Uncharacterized protein | / | 0.468 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.468 | |
| 4k88 | HFG | Bifunctional glutamate/proline--tRNA ligase | 6.1.1.15 | 0.468 | |
| 4ko8 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.468 | |
| 1e1x | NW1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 1l7e | NAI | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.467 | |
| 1p4a | PCP | Pur operon repressor | / | 0.467 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.467 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.467 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.467 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.467 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.466 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.466 | |
| 2r4f | RIE | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.466 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.465 | |
| 2rc3 | NAD | CBS domain | / | 0.465 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.465 | |
| 3i58 | 7NA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.465 | |
| 3kr5 | BEY | M17 leucyl aminopeptidase | / | 0.465 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.465 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.465 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4zz7 | NAD | Methylmalonate-semialdehyde dehydrogenase | / | 0.464 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.463 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.463 | |
| 3x2v | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.463 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.463 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.463 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.463 | |
| 4z17 | PEP | Enolase | / | 0.463 | |
| 1gz8 | MBP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.462 | |
| 3tgy | ASC | Lactoperoxidase | 1.11.1.7 | 0.462 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.462 | |
| 3zy3 | GDP | GDP-fucose protein O-fucosyltransferase 1 | 2.4.1.221 | 0.462 | |
| 4fvz | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.462 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.462 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.462 | |
| 2g8a | UMP | Thymidylate synthase | / | 0.461 | |
| 2ggq | TTP | Dual sugar-1-phosphate nucleotidylyltransferase | / | 0.461 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.461 | |
| 3a8t | ATP | Adenylate isopentenyltransferase | / | 0.461 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.461 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.460 | |
| 2fna | ADP | Uncharacterized protein | / | 0.460 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.460 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.460 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.460 | |
| 4kd1 | 1QK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 4lnk | ADP | Glutamine synthetase | 6.3.1.2 | 0.460 | |
| 1qxo | FMN | Chorismate synthase | / | 0.459 | |
| 2ga9 | AGS | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.459 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.459 | |
| 3ta0 | ATP | Nitrogen regulatory protein P-II (GlnB-3) | / | 0.459 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
| 1pjl | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.458 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.458 | |
| 1y56 | FMN | Uncharacterized protein | / | 0.458 | |
| 1y56 | FMN | 382aa long hypothetical sarcosine oxidase | / | 0.458 | |
| 2bx8 | AZQ | Serum albumin | / | 0.458 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.458 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3qar | QAR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 3ql6 | NIM | Lactoperoxidase | 1.11.1.7 | 0.458 | |
| 4y9u | NAP | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 4yp0 | 5IQ | Histidyl-tRNA synthetase, putative | / | 0.458 | |
| 5aya | X8Z | Metallo-beta-lactamase | / | 0.458 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.457 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.457 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.457 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.457 | |
| 2q6c | HR1 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.457 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4jla | ADP | Adenylate kinase | / | 0.457 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.457 | |
| 4wou | GDP | Phosphoenolpyruvate carboxykinase [GTP] | / | 0.457 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.457 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3cvu | FAD | RE11660p | / | 0.456 | |
| 3ea0 | ATP | ATPase, ParA family | / | 0.456 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.456 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.456 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.456 | |
| 4gto | 7TO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 4la0 | 198 | Serum albumin | / | 0.456 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.456 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.456 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 1fxo | TMP | Glucose-1-phosphate thymidylyltransferase | / | 0.455 | |
| 1jnk | ANP | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
| 1n2g | APC | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.455 | |
| 1tll | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.455 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.455 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.455 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.455 | |
| 3a29 | 2T0 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.455 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.455 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.455 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.454 | |
| 2dpx | GDP | GTP-binding protein RAD | / | 0.454 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.454 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.454 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.454 | |
| 2vwi | ANP | Serine/threonine-protein kinase OSR1 | 2.7.11.1 | 0.454 | |
| 3cvy | FAD | RE11660p | / | 0.454 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.454 | |
| 3w0r | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.454 | |
| 4die | C5P | Cytidylate kinase | / | 0.454 | |
| 4ev0 | CMP | Cyclic AMP receptor protein | / | 0.454 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.454 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.454 | |
| 4k10 | NI9 | Farnesyl pyrophosphate synthase | / | 0.454 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.453 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.453 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4cnz | ADP | Nitrogen regulatory protein P-II 1 | / | 0.453 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.453 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.453 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.452 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.452 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.452 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.452 | |
| 1u2d | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.452 | |
| 2q0f | UTP | Poly(A) polymerase, putative | / | 0.452 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.452 | |
| 3zy6 | GFB | GDP-fucose protein O-fucosyltransferase 1 | 2.4.1.221 | 0.452 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.452 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.452 | |
| 4nt0 | 3DU | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.452 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.452 | |
| 4x2d | ATP | Fic family protein putative filamentation induced by cAMP protein | / | 0.452 | |
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 0.451 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.451 | |
| 1n9l | FMN | Putative blue light receptor | / | 0.451 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.451 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.451 | |
| 2oxn | OAN | Beta-hexosaminidase | / | 0.451 | |
| 2qr1 | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.451 | |
| 2qwl | ADP | Heat shock cognate 71 kDa protein | / | 0.451 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.451 | |
| 3qts | X46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4iaw | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.451 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.451 | |
| 5a06 | NDP | Glucose-fructose oxidoreductase | / | 0.451 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.450 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1fr8 | GDU | Beta-1,4-galactosyltransferase 1 | / | 0.450 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.450 | |
| 1j7l | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.450 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 3a5o | ATP | Major actin | / | 0.450 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.450 | |
| 3n6m | GTP | Genome polyprotein | / | 0.450 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.450 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.450 | |
| 4yb7 | ATP | ATP phosphoribosyltransferase | / | 0.450 | |
| 1i3k | UPG | UDP-glucose 4-epimerase | / | 0.449 | |
| 1jlr | GTP | Uracil phosphoribosyltransferase | / | 0.449 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
| 2bun | FAD | AppA protein | / | 0.449 | |
| 2bxi | AZQ | Serum albumin | / | 0.449 | |
| 2dcn | ADP | 2-keto-3-deoxy-gluconate kinase | / | 0.449 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.449 | |
| 2gn9 | UPG | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.449 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.449 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 3e8x | NAP | BH1520 protein | / | 0.449 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.449 | |
| 3ls8 | AJZ | Phosphatidylinositol 3-kinase catalytic subunit type 3 | 2.7.1.137 | 0.449 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
| 3t8w | DGZ | M17 leucyl aminopeptidase | / | 0.449 | |
| 4bgb | ADP | Predicted molecular chaperone distantly related to HSP70-fold metalloproteases | / | 0.449 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.449 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.449 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.449 | |
| 1glb | ADP | Glycerol kinase | / | 0.448 | |
| 1kqd | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.448 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2gn4 | UD1 | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.448 | |
| 2imk | GTX | AGAP009194-PA | / | 0.448 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4pxn | NAD | Aldehyde dehydrogenase family 7 member B4 | / | 0.448 | |
| 4tnx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.448 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.448 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.447 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1ylr | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.447 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.447 | |
| 2czf | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.447 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.447 | |
| 2vhv | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.447 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.447 | |
| 2xul | ATP | Nitrogen regulatory protein P-II | / | 0.447 | |
| 3sop | GDP | Neuronal-specific septin-3 | / | 0.447 | |
| 4dya | 0MF | Nucleoprotein | / | 0.447 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.447 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.447 | |
| 4nl4 | ADP | Primosomal protein N' | / | 0.447 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.447 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.447 | |
| 1h6b | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.446 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.446 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.446 | |
| 2wd4 | TBV | Ascorbate peroxidase | / | 0.446 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.446 | |
| 2z1m | GDP | GDP-mannose 4,6-dehydratase | / | 0.446 | |
| 3a13 | CAP | Ribulose bisphosphate carboxylase | / | 0.446 | |
| 3dk4 | NDP | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.446 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.446 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.446 | |
| 5ayz | NCN | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | 2.4.2.19 | 0.446 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.446 | |
| 1lol | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.445 | |
| 2p9k | ATP | Actin-related protein 2 | / | 0.445 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 2yiq | YIQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 3rah | O1Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4idv | 13V | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.445 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
| 4iir | ANP | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.445 | |
| 4qnu | GEK | tRNA U34 carboxymethyltransferase | / | 0.445 | |
| 4uxx | ACP | Diacylglycerol kinase | 2.7.1.107 | 0.445 | |
| 5a05 | NDP | Glucose-fructose oxidoreductase | / | 0.445 | |
| 5agl | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 5cku | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.444 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.444 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.444 | |
| 1n7h | GDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.444 | |
| 1y7u | COA | Acyl-CoA hydrolase | / | 0.444 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.444 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.444 | |
| 2wq7 | FAD | RE11660p | / | 0.444 | |
| 2x0e | TYD | WsaF | / | 0.444 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 3nnx | EDD | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4b7t | CWT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.444 | |
| 4ivr | N50 | Thymidine kinase | / | 0.444 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.444 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.444 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 5im3 | DTP | Ribonucleoside-diphosphate reductase | / | 0.444 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.443 | |
| 1qom | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.443 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.443 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.443 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.443 | |
| 2qzs | ADP | Glycogen synthase | 2.4.1.21 | 0.443 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.443 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3c4v | LIP | D-inositol 3-phosphate glycosyltransferase | 2.4.1.250 | 0.443 | |
| 3q9l | ATP | Septum site-determining protein MinD | / | 0.443 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 3x0a | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.443 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.443 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.443 | |
| 4zm3 | PLP | Aminotransferase | / | 0.443 | |
| 4zrn | UPG | UDP-glucose 4-epimerase, putative | / | 0.443 | |
| 1bwf | ATF | Glycerol kinase | / | 0.442 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.442 | |
| 1hk1 | T44 | Serum albumin | / | 0.442 | |
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.442 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
| 1v3s | ATP | Signaling protein | / | 0.442 | |
| 2cfc | KPC | 2-(R)-hydroxypropyl-CoM dehydrogenase | 1.1.1.268 | 0.442 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.442 | |
| 2gqt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.442 | |
| 2hpt | BES | Aminopeptidase N | 3.4.11.2 | 0.442 | |
| 2q6b | HR2 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.442 | |
| 2rl2 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2z4z | SC0 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 3ayk | CGS | Interstitial collagenase | 3.4.24.7 | 0.442 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.442 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.442 | |
| 3pnl | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.442 | |
| 3ruc | UD2 | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4g3p | UD1 | Bifunctional protein GlmU | / | 0.442 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.442 | |
| 4xw6 | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 1okk | GCP | Signal recognition particle protein | / | 0.441 | |
| 1okk | GCP | Signal recognition particle receptor FtsY | / | 0.441 | |
| 1rye | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.441 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 1z0s | ATP | NAD kinase | / | 0.441 | |
| 2hs0 | ATP | Phosphoribosylformylglycinamidine synthase subunit PurL | / | 0.441 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.441 | |
| 2mjp | ANP | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.441 | |
| 2nom | DUT | Poly(A) polymerase, putative | / | 0.441 | |
| 2wb2 | FAD | RE11660p | / | 0.441 | |
| 2yvf | NAD | Ferredoxin reductase | / | 0.441 | |
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.441 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.441 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.441 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3zpo | K0I | Histone demethylase UTY | 1.14.11 | 0.441 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.441 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.441 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4kq1 | U5P | Glycogen [starch] synthase | / | 0.441 | |
| 4o0u | ADN | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4z69 | DIF | Serum albumin | / | 0.441 | |
| 5a65 | TPP | Thiamine-triphosphatase | 3.6.1.28 | 0.441 | |
| 1ao0 | ADP | Amidophosphoribosyltransferase | / | 0.440 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.440 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.440 | |
| 1o5i | NAD | 3-oxoacyl-(Acyl carrier protein) reductase | / | 0.440 | |
| 1pl2 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.440 | |
| 1pnq | NDP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.440 | |
| 1z6q | 195 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 2x2r | X2O | Kinesin-like protein KIF11 | / | 0.440 | |
| 2z08 | ATP | Universal stress protein family | / | 0.440 | |
| 3bkk | KAF | Angiotensin-converting enzyme | 3.2.1 | 0.440 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.440 | |
| 3n82 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.440 | |
| 3o9p | MHI | Periplasmic murein peptide-binding protein | / | 0.440 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.440 | |
| 4cqn | ILA | Leucine--tRNA ligase | / | 0.440 | |
| 4f99 | ADP | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.440 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4jvr | 1MT | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.440 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.440 | |
| 5kj6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |