sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4da5 | 0H7 | Choline kinase alpha | 2.7.1.32 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4da5 | 0H7 | Choline kinase alpha | 2.7.1.32 | 1.000 | |
| 4br3 | U85 | Choline kinase alpha | 2.7.1.32 | 0.593 | |
| 3zm9 | QMQ | Choline kinase alpha | 2.7.1.32 | 0.564 | |
| 4cg8 | G8S | Choline kinase alpha | 2.7.1.32 | 0.517 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.514 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.509 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.508 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.508 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.497 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.495 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.495 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.495 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.490 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.490 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.490 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.486 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.485 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.484 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.483 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.482 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.482 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.482 | |
| 3i0o | SMI | Spectinomycin phosphotransferase | / | 0.480 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.476 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.476 | |
| 1xid | ASC | Xylose isomerase | 5.3.1.5 | 0.474 | |
| 3hr4 | FMN | Nitric oxide synthase, inducible | 1.14.13.39 | 0.474 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3fi8 | OPE | Choline kinase | / | 0.471 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.470 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.469 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.468 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.468 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.467 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.467 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.467 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.466 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.466 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.464 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.464 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.464 | |
| 4a7y | NHF | Aldos-2-ulose dehydratase | / | 0.464 | |
| 1j36 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.463 | |
| 1qw5 | 14W | Nitric oxide synthase, inducible | 1.14.13.39 | 0.463 | |
| 3gf4 | U5P | UDP-galactopyranose mutase | 5.4.99.9 | 0.463 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.463 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.462 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.462 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.462 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.462 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.461 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.461 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.460 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.460 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.460 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.459 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.459 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.459 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.458 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.458 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.457 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.457 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.457 | |
| 2wea | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.457 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.457 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.457 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.457 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.456 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.456 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.456 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4f1q | 0RZ | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.456 | |
| 1dtn | APG | Mandelate racemase | / | 0.455 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.455 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.455 | |
| 3b5i | SAH | Indole-3-acetate O-methyltransferase 1 | / | 0.455 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.455 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4gaa | BES | Leukotriene A(4) hydrolase | / | 0.455 | |
| 4j7h | TRH | PCZA361.3 | / | 0.455 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.454 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.454 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.454 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.454 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.454 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4hcy | 0YN | Transketolase | / | 0.454 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.454 | |
| 5agl | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.454 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.453 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.453 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.453 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.453 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.453 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.453 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 1wkg | POI | [LysW]-aminoadipate semialdehyde transaminase | / | 0.452 | |
| 2j62 | GSZ | O-GlcNAcase NagJ | / | 0.452 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.452 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.452 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.452 | |
| 4j17 | 1HQ | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.452 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.452 | |
| 2v8p | CDP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.451 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.451 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.451 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.450 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.450 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.449 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.449 | |
| 4h6p | FMN | Chromate reductase | / | 0.449 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.449 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.448 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.448 | |
| 4fou | C2E | Uncharacterized protein | / | 0.448 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.447 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.447 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.447 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4zwe | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.447 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.446 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.446 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 2r86 | ATP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.446 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.446 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.446 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.446 | |
| 4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.446 | |
| 4tny | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.446 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.445 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.445 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.445 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.445 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.445 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.444 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.444 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.444 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.444 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.444 | |
| 4dyb | 0MH | Nucleoprotein | / | 0.444 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.443 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.443 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.443 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4nv1 | TYD | Formyl transferase | / | 0.443 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.443 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.442 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2j7d | GI1 | Beta-glucosidase A | 3.2.1.21 | 0.442 | |
| 2v5u | FMN | Flavodoxin | / | 0.442 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 4a7z | AY9 | Aldos-2-ulose dehydratase | / | 0.442 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.442 | |
| 5hvn | NAD | 3-dehydroquinate synthase | / | 0.442 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.442 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 2x94 | X94 | Angiotensin-converting enzyme | 3.4.15.1 | 0.441 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.441 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.441 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.440 | |
| 1ltz | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.440 | |
| 2d2g | DZZ | Phosphotriesterase | / | 0.440 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2vfz | UPF | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.440 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.440 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.440 | |
| 3fzm | 3GO | Heat shock cognate 71 kDa protein | / | 0.440 | |
| 3irh | DTP | HD domain protein | / | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3wb5 | 0B4 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.440 | |
| 4rel | KMP | Glycosyltransferase | / | 0.440 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4xcz | T3Q | Qdtf | / | 0.440 |