Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3sfx | JAN | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3sfx | JAN | Uncharacterized protein | / | 1.000 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.721 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.691 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.621 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.619 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.616 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.611 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.611 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.605 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.605 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.603 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.602 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.601 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.600 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.589 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.588 | |
| 3e30 | ED4 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.588 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.586 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.586 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.584 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.583 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.572 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.567 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.567 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.564 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.562 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.559 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.558 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.557 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.555 | |
| 3pz4 | 3PZ | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.552 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.551 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.547 | |
| 4gtr | 7TR | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.543 | |
| 4gtm | 7TM | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.533 | |
| 2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.532 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.529 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.527 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.512 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.510 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.499 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.498 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.498 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.493 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.488 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.488 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.488 | |
| 1lke | DOG | Bilin-binding protein | / | 0.487 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.486 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.485 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.483 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.482 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.482 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.481 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.478 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 0.476 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.475 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.474 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.474 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.473 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.472 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.471 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.471 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.470 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.469 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.469 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.469 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.468 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.468 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4k88 | HFG | Bifunctional glutamate/proline--tRNA ligase | 6.1.1.15 | 0.467 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.465 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.465 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.465 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.464 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.463 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.463 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.463 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.463 | |
| 4xwt | U5P | Ribonuclease J | / | 0.463 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.462 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.461 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.461 | |
| 3rsl | GNP | GTPase HRas | / | 0.461 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.460 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.460 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.460 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.460 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.460 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.460 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.460 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.459 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.459 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.459 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1c7o | PPG | Hemolysin | / | 0.458 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.458 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.458 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.458 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.458 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.457 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.457 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.457 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.457 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.457 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.457 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.456 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.456 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.455 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.455 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.455 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.454 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.454 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.454 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.454 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4ihi | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.454 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.454 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.453 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.453 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.453 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.452 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2a3c | PNX | Endochitinase B1 | 3.2.1.14 | 0.452 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.452 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.452 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 1pt5 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.451 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.451 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.451 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.451 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.451 | |
| 5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.451 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.450 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.450 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.450 | |
| 3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.450 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.449 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.449 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3ddc | GNP | GTPase HRas | / | 0.449 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.449 | |
| 3p9t | TCL | Repressor | / | 0.449 | |
| 1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.448 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.448 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.448 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.448 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.448 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2nr4 | FMN | Conserved protein | / | 0.448 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.448 | |
| 4lut | DCS | Alanine racemase | / | 0.448 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.448 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.447 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.447 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.447 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.447 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.447 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.446 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.446 | |
| 2r86 | ATP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.446 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.446 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3eku | CY9 | Actin-5C | / | 0.446 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3kyb | FMN | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.446 | |
| 1g6o | ADP | Cag alpha | / | 0.445 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.445 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.445 | |
| 3q5p | TAC | Multidrug-efflux transporter 1 regulator | / | 0.445 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.445 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3bt9 | DEQ | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.444 | |
| 3lbn | GNP | GTPase HRas | / | 0.444 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.443 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.443 | |
| 1uze | EAL | Angiotensin-converting enzyme | 3.2.1 | 0.443 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2h63 | NAP | Biliverdin reductase A | 1.3.1.24 | 0.443 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.442 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.442 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3af2 | ACP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.442 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.442 | |
| 1rs6 | DP2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.441 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.441 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.441 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.440 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.440 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.440 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.440 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.440 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3frk | TQP | QdtB | / | 0.440 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.440 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.440 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.440 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 |