sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 1.000 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.603 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.590 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.584 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.576 | |
| 2ejz | SAH | Diphthine synthase | / | 0.519 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.519 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.515 | |
| 5dp2 | NAP | CurF | / | 0.508 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.499 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.496 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 3b9l | AZZ | Serum albumin | / | 0.495 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.495 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.494 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.493 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.490 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.489 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.488 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.487 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.487 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.487 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.486 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.485 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.485 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.484 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.484 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.483 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 5a3b | APR | SIR2 family protein | / | 0.483 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.482 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.481 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.480 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.479 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.479 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.477 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.477 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.476 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.475 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.475 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.474 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.474 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.473 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.472 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.472 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.472 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 1w7h | 3IP | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.471 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2xvv | 9DN | Serum albumin | / | 0.471 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.471 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.471 | |
| 1g28 | FMN | PHY3 | / | 0.470 | |
| 2xvw | 9NR | Serum albumin | / | 0.470 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.470 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.470 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1vce | SAH | Diphthine synthase | / | 0.469 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.469 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.468 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.467 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.467 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.467 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.466 | |
| 1osv | CHC | Bile acid receptor | / | 0.466 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.466 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.466 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 1b48 | HAG | Glutathione S-transferase A4 | 2.5.1.18 | 0.465 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.465 | |
| 2a8y | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.465 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.465 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.465 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.464 | |
| 2ejk | SAH | Diphthine synthase | / | 0.464 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.464 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.464 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.464 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2bxq | IMN | Serum albumin | / | 0.463 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.463 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.463 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.463 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.463 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.462 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.462 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.462 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.462 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.462 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.462 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.462 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4v12 | POG | MaoC like domain protein | / | 0.462 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.461 | |
| 2v1a | FMN | NPH1-1 | / | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.461 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.460 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3t94 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.460 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.460 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.459 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.459 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.459 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.458 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.458 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.458 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.458 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.458 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4l8u | 9AZ | Serum albumin | / | 0.458 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.458 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.458 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.457 | |
| 1fml | RTL | Retinol dehydratase | / | 0.457 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.457 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.457 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.457 | |
| 2egl | SAH | Diphthine synthase | / | 0.457 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.457 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.457 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.457 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.457 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.456 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.456 | |
| 2dsg | SAH | Diphthine synthase | / | 0.456 | |
| 2e08 | SAH | Diphthine synthase | / | 0.456 | |
| 2eeq | SAH | Diphthine synthase | / | 0.456 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.456 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.456 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.456 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.456 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.456 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.456 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.456 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.456 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.455 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.455 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.455 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.455 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.455 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.455 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.455 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.454 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.454 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.454 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.454 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.454 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.454 | |
| 1s7n | COA | Acetyl transferase | / | 0.453 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.453 | |
| 2y3r | TRK | TamL | / | 0.453 | |
| 3e8x | NAP | BH1520 protein | / | 0.453 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 3v2u | ATP | Protein GAL3 | / | 0.453 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.453 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.453 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.453 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.453 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.453 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.452 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.452 | |
| 2dsh | SAH | Diphthine synthase | / | 0.452 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.452 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.452 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.452 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.452 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.452 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.452 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.451 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.451 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.451 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.451 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1r2j | FAD | FkbI | / | 0.450 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.450 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3bx5 | 304 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.450 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.450 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.450 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.449 | |
| 1wng | SAH | Diphthine synthase | / | 0.449 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.449 | |
| 2e07 | SAH | Diphthine synthase | / | 0.449 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.449 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.449 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.449 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.449 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.449 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.449 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 2dxv | SAH | Diphthine synthase | / | 0.448 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.448 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.448 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 2emr | SAH | Diphthine synthase | / | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.447 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.447 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.447 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.447 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.447 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.446 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.446 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.446 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 2dsi | SAH | Diphthine synthase | / | 0.446 | |
| 2e16 | SAH | Diphthine synthase | / | 0.446 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.446 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.446 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 5doz | NDP | JamJ | / | 0.446 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.445 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.445 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.445 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 2e8h | SAH | Diphthine synthase | / | 0.445 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.445 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.445 | |
| 2z6r | SAH | Diphthine synthase | / | 0.445 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.445 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.445 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.445 | |
| 4iae | 1DX | Alr2278 protein | / | 0.445 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 5djt | FMN | NPH1-2 | / | 0.445 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.444 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.444 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.444 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.444 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.444 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.444 | |
| 3eku | CY9 | Actin-5C | / | 0.444 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3gob | HXX | DdmC | / | 0.444 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.444 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.444 | |
| 5efw | FMN | NPH1-1 | / | 0.444 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.443 | |
| 2bxm | IMN | Serum albumin | / | 0.443 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.443 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.443 | |
| 2owu | SAH | Diphthine synthase | / | 0.443 | |
| 2p6l | SAH | Diphthine synthase | / | 0.443 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.443 | |
| 2y3s | TIR | TamL | / | 0.443 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.443 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.443 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.443 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.443 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.443 | |
| 1c7o | PPG | Hemolysin | / | 0.442 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.442 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.442 | |
| 2e8q | SAH | Diphthine synthase | / | 0.442 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.442 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.442 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.442 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.442 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.442 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.442 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.442 | |
| 4jxr | ACO | Acetyltransferase | / | 0.442 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.442 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.442 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.441 | |
| 2el3 | SAH | Diphthine synthase | / | 0.441 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.441 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.441 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.441 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.441 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.441 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.441 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.441 | |
| 4g1c | CNA | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.441 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.441 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.441 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 5il1 | SAM | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.441 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.440 | |
| 1dv2 | ATP | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.440 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.440 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.440 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.440 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.440 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.440 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.440 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.440 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.440 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.440 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.440 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.440 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 4o2z | 046 | Mitogen-activated protein kinase | / | 0.440 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 | |
| 4y0k | NAP | AntE | / | 0.440 |