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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3c5uP41Mitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3c5uP41Mitogen-activated protein kinase 14/1.000
3zsh469Mitogen-activated protein kinase 14/0.561
3hub469Mitogen-activated protein kinase 14/0.559
3fknFKNMitogen-activated protein kinase 14/0.556
3fl4FL4Mitogen-activated protein kinase 14/0.553
3ds6A17Mitogen-activated protein kinase 14/0.550
3fkoFKOMitogen-activated protein kinase 14/0.544
3itzP66Mitogen-activated protein kinase 14/0.540
3fmmXI2Mitogen-activated protein kinase 14/0.527
2gfsPQBMitogen-activated protein kinase 14/0.522
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.516
1zzlTZYMitogen-activated protein kinase 14/0.512
2yixYIXMitogen-activated protein kinase 14/0.512
4ih8B43Calmodulin-domain protein kinase 1/0.512
3e92G6AMitogen-activated protein kinase 14/0.510
3bx5304Mitogen-activated protein kinase 14/0.504
3ttjJBIMitogen-activated protein kinase 102.7.11.240.503
3zlnH0YBcl-2-like protein 1/0.503
2excJNKMitogen-activated protein kinase 102.7.11.240.501
3pg3DG7Mitogen-activated protein kinase 14/0.501
1di8DTQCyclin-dependent kinase 22.7.11.220.495
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.495
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.494
3uvqFS8Mitogen-activated protein kinase 14/0.494
3gc9B45Mitogen-activated protein kinase 112.7.11.240.492
4iaq2GM5-hydroxytryptamine receptor 1B/0.491
1wbwLI4Mitogen-activated protein kinase 14/0.490
2b1pAIZMitogen-activated protein kinase 102.7.11.240.490
1pmn984Mitogen-activated protein kinase 102.7.11.240.488
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.487
4ma628EAra h 8 allergen/0.487
1re9DSOCamphor 5-monooxygenase1.14.15.10.485
3ttiKBIMitogen-activated protein kinase 102.7.11.240.484
4iarERM5-hydroxytryptamine receptor 1B/0.484
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.482
3qakUKAAdenosine receptor A2a/0.482
3lb8FADPutidaredoxin reductase1.18.1.50.481
3rinI2OMitogen-activated protein kinase 14/0.481
4fnyI3KALK tyrosine kinase receptor2.7.10.10.481
1ove358Mitogen-activated protein kinase 14/0.480
3roc29AMitogen-activated protein kinase 14/0.479
3zep1NXTyrosine-protein kinase JAK32.7.10.20.479
2itzIREEpidermal growth factor receptor2.7.10.10.478
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.477
4j95ACPFibroblast growth factor receptor 2/0.477
4wa9AXITyrosine-protein kinase ABL12.7.10.20.477
1fbmRTLCartilage oligomeric matrix protein/0.475
3eigMTXDihydrofolate reductase1.5.1.30.475
3kq7KQ7Mitogen-activated protein kinase 14/0.475
4b8mVX6Aurora kinase B-A2.7.11.10.475
4iji99TGlutathione S-transferase-like protein YibF/0.475
4ysjADPCalmodulin-like domain protein kinase/0.475
2po7CHDFerrochelatase, mitochondrial4.99.1.10.474
3vquO22Dual specificity protein kinase TTK2.7.12.10.474
4uyf73BBromodomain-containing protein 2/0.474
2qoqANPEphrin type-A receptor 32.7.10.10.473
1qbu846Gag-Pol polyprotein3.4.23.160.472
2zb1GK4Mitogen-activated protein kinase 14/0.472
2izsBRQCasein kinase I isoform gamma-32.7.11.10.471
3flwFLWMitogen-activated protein kinase 14/0.471
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.471
3r7kFDAProbable acyl CoA dehydrogenase/0.471
1ppjANYCytochrome b/0.470
1v0jFADUDP-galactopyranose mutase5.4.99.90.470
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.470
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.470
4twpAXITyrosine-protein kinase ABL12.7.10.20.470
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.470
1c70L75Protease/0.469
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.469
2w4iVGAGlutamate racemase/0.469
3kvxFMYMitogen-activated protein kinase 102.7.11.240.469
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.469
3s4qNK0Mitogen-activated protein kinase 14/0.469
4btjATPTau-tubulin kinase 12.7.11.10.469
2ftoCB3Thymidylate synthase/0.468
2g78REACellular retinoic acid-binding protein 2/0.468
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.468
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.468
4aotGW8Serine/threonine-protein kinase 102.7.11.10.468
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.468
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.467
1k6cMK1Gag-Pol polyprotein3.4.23.160.466
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.466
3fmn530Mitogen-activated protein kinase 14/0.466
3p6nDSOCamphor 5-monooxygenase1.14.15.10.466
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.466
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.466
4zseANPEpidermal growth factor receptor2.7.10.10.466
1zyjBI5Mitogen-activated protein kinase 14/0.465
2uy0HV1Gag-Pol polyprotein3.4.23.160.465
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.465
3mnrSD1Heat shock protein HSP 90-alpha/0.465
3p4tFAOPutative acyl-CoA dehydrogenase/0.465
1kk4ACOStreptogramin A acetyltransferase2.3.10.464
1w5vBE3Gag-Pol polyprotein3.4.23.160.464
2nnpROCProtease/0.464
2y05NAPProstaglandin reductase 1/0.464
3p6pA6BCamphor 5-monooxygenase1.14.15.10.464
3tvuB37Acetyl-CoA carboxylase/0.464
4j5j478Gag-Pol polyprotein3.4.23.160.464
5awmANPStress-activated protein kinase JNK2.7.11.240.464
1efvFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.463
2ebaFADPutative glutaryl-CoA dehydrogenase/0.463
2vttLZDCyclin-dependent kinase 22.7.11.220.463
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.463
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.463
3mpaSB2Mitogen-activated protein kinase 14/0.463
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.463
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.463
4nka2K7Fibroblast growth factor receptor 1/0.463
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.462
1ig1ANPDeath-associated protein kinase 12.7.11.10.462
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.462
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.462
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.462
2xrwANPMitogen-activated protein kinase 82.7.11.240.462
3d7zGK5Mitogen-activated protein kinase 14/0.462
3zeiAWHO-acetylserine sulfhydrylase/0.462
3zuxTCHTransporter/0.462
1t7j478Gag-Pol polyprotein3.4.23.160.461
1tduCB3Thymidylate synthase/0.461
1v9aSAHUncharacterized protein/0.461
2o0uC0MMitogen-activated protein kinase 102.7.11.240.461
2qa2FADPolyketide oxygenase CabE/0.461
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.461
3fc152PMitogen-activated protein kinase 14/0.461
3ol5SAWCamphor 5-monooxygenase1.14.15.10.461
3zuyTCHTransporter/0.461
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.461
4zj8SUVOrexin receptor type 1/0.461
1uykPUXHeat shock protein HSP 90-alpha/0.460
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.460
3l0lHC3Nuclear receptor ROR-gamma/0.460
1iyzNDPProbable quinone oxidoreductase/0.459
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2fwyH64Heat shock protein HSP 90-alpha/0.459
2ykeYKEHeat shock protein HSP 90-alpha/0.459
3deiRXBCaspase-33.4.22.560.459
3so9017Pol protein/0.459
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.459
4s0vSUVOrexin receptor type 2/0.459
1cqp803Integrin alpha-L/0.458
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.458
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
2pvyACPFibroblast growth factor receptor 2/0.458
2q61SF1Peroxisome proliferator-activated receptor gamma/0.458
2xclANPPhosphoribosylamine--glycine ligase/0.458
3ac1KZITyrosine-protein kinase Lck2.7.10.20.458
3dejRXCCaspase-33.4.22.560.458
3lfeZ84Mitogen-activated protein kinase 14/0.458
3owaFADAcyl-CoA dehydrogenase/0.458
4ki8ADP60 kDa chaperonin/0.458
1efpFADElectron transfer flavoprotein subunit alpha/0.457
1khrCOAStreptogramin A acetyltransferase2.3.10.457
1qcjAPTAntiviral protein I3.2.2.220.457
1yb5NAPQuinone oxidoreductase1.6.5.50.457
2bb9AKCGag-Pol polyprotein3.4.23.160.457
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.457
2fzhDH1Dihydrofolate reductase1.5.1.30.457
2j7t274Serine/threonine-protein kinase 102.7.11.10.457
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.457
3p6mDSOCamphor 5-monooxygenase1.14.15.10.457
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.457
4a6bQG8Gag-Pol polyprotein3.4.23.160.457
4ez8DHFThymidylate synthase2.1.1.450.457
4i7fNVEGag-Pol polyprotein2.7.7.490.457
4kiq1RAMitogen-activated protein kinase 14/0.457
4ux9ANPMitogen-activated protein kinase 82.7.11.240.457
5br7FADUDP-galactopyranose mutase/0.457
1bv7XV6Gag-Pol polyprotein3.4.23.160.456
1d4lPI9Gag-Pol polyprotein3.4.23.160.456
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1hiiC20Gag-Pol polyprotein/0.456
1ju6LYAThymidylate synthase2.1.1.450.456
1qrpHH0Pepsin A-43.4.23.10.456
2b60RITPol polyprotein/0.456
2hziJINTyrosine-protein kinase ABL12.7.10.20.456
3b20NADGlyceraldehyde-3-phosphate dehydrogenase/0.456
3gc8B45Mitogen-activated protein kinase 112.7.11.240.456
3hllI45Mitogen-activated protein kinase 14/0.456
3iw5DF3Mitogen-activated protein kinase 14/0.456
3jynNDPQuinone oxidoreductase/0.456
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.456
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.456
4b8wNAPGDP-L-fucose synthase1.1.1.2710.456
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.456
4gt3ATPMitogen-activated protein kinase 12.7.11.240.456
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.455
1hpoUNIGag-Pol polyprotein3.4.23.160.455
1qvnFRIInterleukin-2/0.455
2cduFADNADH oxidase/0.455
2fziDH3Dihydrofolate reductase1.5.1.30.455
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.455
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.455
3dt1P40Mitogen-activated protein kinase 14/0.455
3r9dX6BCyclin-dependent kinase 22.7.11.220.455
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.455
3t3c017Gag-Pol polyprotein3.4.23.160.455
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.455
4l8u9AZSerum albumin/0.455
4nieNBHNuclear receptor ROR-gamma/0.455
4y9lFADAcyl-CoA dehydrogenase family member 11/0.455
8dfrNDPDihydrofolate reductase1.5.1.30.455
1blzACVIsopenicillin N synthase1.21.3.10.454
1ddsMTXDihydrofolate reductase1.5.1.30.454
1ha3MAUElongation factor Tu-A/0.454
1n83CLRNuclear receptor ROR-alpha/0.454
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.454
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.454
2i4uDJRProtease/0.454
2obyNAPQuinone oxidoreductase PIG310.454
3dmtNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.454
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.454
3oxv478Gag-Pol polyprotein3.4.23.160.454
3q44D50M1 family aminopeptidase3.4.110.454
3zpuM8BGag-Pol polyprotein3.4.23.160.454
4dfg0JVGag-Pol polyprotein3.4.23.160.454
4dqh017Gag-Pol polyprotein/0.454
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.454
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1rfuADPPyridoxal kinase2.7.1.350.453
2a4fAAUV-1 protease/0.453
2avvMK1Gag-Pol polyprotein3.4.23.160.453
2dbzNAPGlyoxylate reductase1.1.1.260.453
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.453
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.453
2xlrFADPutative flavin-containing monooxygenase/0.453
3dk1G05Gag-Pol polyprotein3.4.23.160.453
3f1kNAPUncharacterized oxidoreductase YciK10.453
3i6oGR6Gag-Pol polyprotein3.4.23.160.453
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.453
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.453
4id71G0Activated CDC42 kinase 1/0.453
4l9kEHFSerum albumin/0.453
4qe6JN3Bile acid receptor/0.453
1h36R88Squalene--hopene cyclase4.2.1.1290.452
1ida0POGag-Pol polyprotein3.4.23.470.452
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.452
1tkgSSAThreonine--tRNA ligase6.1.1.30.452
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.452
2a1uFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.452
2fdd385Pol protein/0.452
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.452
2p15EZTEstrogen receptor/0.452
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.452
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.452
3ce31FNHepatocyte growth factor receptor2.7.10.10.452
3d0bSNXHeat shock protein HSP 90-alpha/0.452
3tdaPN0Cytochrome P450 2D6/0.452
3vnt0JAVascular endothelial growth factor receptor 22.7.10.10.452
4a6cQG9Gag-Pol polyprotein3.4.23.160.452
4anqVGHALK tyrosine kinase receptor2.7.10.10.452
4bbfO19Tyrosine-protein kinase JAK2/0.452
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.452
5eypLOCTubulin beta chain/0.452
5f0a1FBcGMP-dependent protein kinase, putative/0.452
5ifiPRXAcetyl-coenzyme A synthetase/0.452
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.451
1gypNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.451
1hb1OCVIsopenicillin N synthase1.21.3.10.451
2idkC2FGlycine N-methyltransferase2.1.1.200.451
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.451
2rc6NAPFerredoxin--NADP reductase/0.451
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.451
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.451
3fpaDTBATP-dependent dethiobiotin synthetase BioD/0.451
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3i7eDJRGag-Pol polyprotein/0.451
3ksdNADGlyceraldehyde-3-phosphate dehydrogenase 1/0.451
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.451
3nww3NWMitogen-activated protein kinase 14/0.451
3vfa031Gag-Pol polyprotein3.4.23.160.451
4b8zNAPGDP-L-fucose synthase1.1.1.2710.451
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.451
4oztP1AEcdysone receptor, putative/0.451
5cnoANPEpidermal growth factor receptor2.7.10.10.451
5k2cZMAAdenosine receptor A2a/0.451
4uhrNGIAdenosine receptor A2a/0.451
1c6yMK1Protease/0.450
1m7qDQOMitogen-activated protein kinase 14/0.450
1xkdNAPIsocitrate dehydrogenase [NADP]/0.450
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.450
2henADPEphrin type-B receptor 22.7.10.10.450
2qnqQN3Gag-Pol polyprotein3.4.23.160.450
2z1qFADAcyl-CoA dehydrogenase/0.450
3bgxMEFThymidylate synthase/0.450
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.450
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.450
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.450
3ntgD72Prostaglandin G/H synthase 21.14.99.10.450
3o6o94MHeat shock protein 83/0.450
3oxcROCProtease/0.450
3sa8K83Protease/0.450
3uibSB2Putative mitogen-activated protein kinase/0.450
3zpsEQMGag-Pol polyprotein3.4.23.160.450
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.450
4bgg844Activin receptor type-12.7.11.300.450
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.450
4i5cC5ITyrosine-protein kinase JAK1/0.450
5dozNDPJamJ/0.450
5e8wSTUTGF-beta receptor type-12.7.11.300.450
1diuBDMDihydrofolate reductase1.5.1.30.449
1qbsDMPGag-Pol polyprotein3.4.23.160.449
1tysDHFThymidylate synthase/0.449
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2cen4AHProtease/0.449
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.449
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.449
2fzwNADAlcohol dehydrogenase class-31.1.1.10.449
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.449
2w4jADPDeath-associated protein kinase 12.7.11.10.449
2wotZZGTGF-beta receptor type-12.7.11.300.449
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.449
3ocgOCGMitogen-activated protein kinase 14/0.449
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.449
3t2kFADSulfide-quinone reductase/0.449
3u1y03IUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.449
3up0D7SaceDAF-12/0.449
4g48PZBMycocyclosin synthase1.14.21.90.449
4klaCHDFerrochelatase, mitochondrial4.99.1.10.449
4ku5DCC3-oxoacyl-[ACP] synthase III/0.449
4qnyANPMitogen activated protein kinase, putative/0.449
4tuvCPZCytochrome P450 1191.140.449
6gswGPSGlutathione S-transferase Mu 12.5.1.180.449
1d4jMSCGag-Pol polyprotein3.4.23.160.448
1idb0DOGag-Pol polyprotein/0.448
1sguMK1Gag-Pol polyprotein3.4.23.160.448
1uyePU9Heat shock protein HSP 90-alpha/0.448
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2qe6SAMUncharacterized protein/0.448
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.448
3fmlFMLMitogen-activated protein kinase 14/0.448
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.448
3nf4FADAcyl-CoA dehydrogenase domain-containing protein/0.448
3nfaCBJGag-Pol polyprotein/0.448
3s54017Protease/0.448
3sdkP3NProteasome subunit beta type-53.4.25.10.448
3sdkP3NProteasome subunit beta type-63.4.25.10.448
3sjzGNPTranslation initiation factor 2 subunit gamma/0.448
3st5G89Gag-Pol polyprotein3.4.23.160.448
3v013V0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
3w2o03PEpidermal growth factor receptor2.7.10.10.448
3w33W19Epidermal growth factor receptor2.7.10.10.448
4isk1JYThymidylate synthase/0.448
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.448
4z9g1Q5Corticotropin-releasing factor receptor 1/0.448
1cbrREACellular retinoic acid-binding protein 1/0.447
1cbsREACellular retinoic acid-binding protein 2/0.447
1hwr216Gag-Pol polyprotein3.4.23.160.447
1meuDMPGag-Pol polyprotein3.4.23.160.447
1ouy094Mitogen-activated protein kinase 14/0.447
1z1rHBHGag-Pol polyprotein3.4.23.160.447
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
2ieo017Protease/0.447
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.447
3lu8IQXSerum albumin/0.447
4a84DXCMajor pollen allergen Bet v 1-A/0.447
4ansVGHALK tyrosine kinase receptor2.7.10.10.447
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4jboWPHAurora kinase A2.7.11.10.447
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
4o7uTHFThymidylate synthase/0.447
4pmjNAPPutative oxidoreductase/0.447
4qi5FADCellobiose dehydrogenase/0.447
4xwtU5PRibonuclease J/0.447
4ug2NGIAdenosine receptor A2a/0.447
1mesDMPGag-Pol polyprotein3.4.23.160.446
1oiyN41Cyclin-dependent kinase 22.7.11.220.446
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.446
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.446
1qxsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.446
1yqj6NPMitogen-activated protein kinase 14/0.446
2ghmLICMitogen-activated protein kinase 14/0.446
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2jj1PITATP synthase subunit alpha, mitochondrial/0.446
2jj1PITATP synthase subunit beta, mitochondrial3.6.3.140.446
2jj1PITATP synthase subunit gamma, mitochondrial/0.446
2o7pNAPRiboflavin biosynthesis protein RibD/0.446
2q5p241Peroxisome proliferator-activated receptor gamma/0.446
2qd9LGFMitogen-activated protein kinase 14/0.446
2qhzMZ2Gag-Pol polyprotein/0.446
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.446
2xpwOTCTetracycline repressor protein class D/0.446
2ydvNECAdenosine receptor A2a/0.446
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3e5aVX6Aurora kinase A2.7.11.10.446
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.446
3hp552PMitogen-activated protein kinase 14/0.446
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.446
3o3nIRC(R)-2-hydroxyisocaproyl-CoA dehydratase alpha subunit/0.446
3qudN3FMitogen-activated protein kinase 14/0.446
3slkNDPPolyketide synthase extender module 2/0.446
3wsjMK1Protease/0.446
3zsi52PMitogen-activated protein kinase 14/0.446
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.446
4g170VNCasein kinase I isoform gamma-32.7.11.10.446
4jqh1MFAlr2278 protein/0.446
4tyj0LIFibroblast growth factor receptor 42.7.10.10.446
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.446
5k2bZMAAdenosine receptor A2a/0.446
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.445
1fwkADPHomoserine kinase2.7.1.390.445
1hvrXK2Gag-Pol polyprotein/0.445
1nsfATPVesicle-fusing ATPase3.6.4.60.445
1yqxNAPSinapyl alcohol dehydrogenase/0.445
2bpy3INGag-Pol polyprotein3.4.23.160.445
2e0nSAHPrecorrin-2 C20-methyltransferase/0.445
2g5cNADPrephenate dehydrogenase/0.445
2h55DZ8Heat shock protein HSP 90-alpha/0.445
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.445
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2q5g1FAPeroxisome proliferator-activated receptor delta/0.445
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.445
3d1xROCGag-Pol polyprotein3.4.23.160.445
3oom507Activin receptor type-12.7.11.300.445
3q8uADPNucleoside diphosphate kinase/0.445
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3uk6ADPRuvB-like 23.6.4.120.445
3w0aDS5Vitamin D3 receptor/0.445
4eh4IRGMitogen-activated protein kinase 14/0.445
4g1d0VKVitamin D3 receptor A/0.445
4hnf16WCasein kinase I isoform delta2.7.11.10.445
4mleVO1Glucokinase2.7.1.20.445
4q1y017Gag-Pol polyprotein3.4.23.160.445
5c7hNDPPutative oxidoreductase/0.445
6upjNIUGag-Pol polyprotein/0.445
1bygSTUTyrosine-protein kinase CSK/0.444
1dv2ATPBiotin carboxylase6.3.4.140.444
1ebk0Q4Gag-Pol polyprotein3.4.23.160.444
1pz0NAPProtein IolS1.1.10.444
1uycPU7Heat shock protein HSP 90-alpha/0.444
1wbmBLLPol protein/0.444
1wc1TATAdenylate cyclase/0.444
1y0s331Peroxisome proliferator-activated receptor delta/0.444
1z1hHBBGag-Pol polyprotein3.4.23.160.444
2bl4NADLactaldehyde reductase1.1.1.770.444
2givACOHistone acetyltransferase KAT8/0.444
2harOCCVitamin D3 receptor/0.444
2jd1NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.444
2qi1MZ4Gag-Pol polyprotein/0.444
2w2lNADD-mandelate dehydrogenase/0.444
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.444
2ydoADNAdenosine receptor A2a/0.444
2yyyNAPGlyceraldehyde-3-phosphate dehydrogenase1.2.1.590.444
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.444
3lfbZ87Mitogen-activated protein kinase 14/0.444
3p9tTCLRepressor/0.444
3ttp017Gag-Pol polyprotein3.4.23.160.444
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.444
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4e5kNADPhosphonate dehydrogenase1.20.1.10.444
4eiyZMAAdenosine receptor A2a/0.444
4elf35IDihydrofolate reductase/0.444
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.444
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.444
4ia2BIVVitamin D3 receptor A/0.444
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4tvbNADHomospermidine synthase2.5.1.440.444
5iu86DZAdenosine receptor A2a/0.444
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.443
1kzjCB3Thymidylate synthase/0.443
1msmJE2Gag-Pol polyprotein3.4.23.160.443
1tsxUMPThymidylate synthase/0.443
1w7h3IPMitogen-activated protein kinase 14/0.443
1yw2PGJMitogen-activated protein kinase 14/0.443
2gejGDDPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.443
2gqfFADUncharacterized protein HI_0933/0.443
2gtmLIDMitogen-activated protein kinase 14/0.443
2hw1ANPKetohexokinase/0.443
2oxiNADAlcohol dehydrogenase E chain1.1.1.10.443
2pk5075Protease/0.443
2z3uCRRCytochrome P450/0.443
3ekt017Gag-Pol polyprotein3.4.23.160.443
3gggNADPrephenate dehydrogenase/0.443
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.443
3hng8STVascular endothelial growth factor receptor 12.7.10.10.443
3hp2P36Mitogen-activated protein kinase 14/0.443
3ix9MTXDihydrofolate reductase1.5.1.30.443
3kf7L9GMitogen-activated protein kinase 14/0.443
3ogqAB1Pol polyprotein/0.443
3upjU03Gag-Pol polyprotein/0.443
3vt65YIVitamin D3 receptor/0.443
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.443
4d0lGSPRas-related protein Rab-11A/0.443
4djqM86Pol polyprotein/0.443
4ele31IDihydrofolate reductase/0.443
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.443
4hgs15GCasein kinase I isoform gamma-32.7.11.10.443
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.443
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.443
4k2xFADPolyketide oxygenase/hydroxylase/0.443
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.443
4pytFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.443
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1a8g2Z4Gag-Pol polyprotein3.4.23.160.442
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.442
1ebwBEIGag-Pol polyprotein3.4.23.160.442
1g3mPCQEstrogen sulfotransferase2.8.2.40.442
1iepSTITyrosine-protein kinase ABL12.7.10.20.442
1nmdATPMajor actin/0.442
1ohr1UNV-1 PROTEASE protein/0.442
1qbrXV6Gag-Pol polyprotein3.4.23.160.442
1w83L11Mitogen-activated protein kinase 14/0.442
1x98NAPAldose reductase1.1.1.210.442
2c6eHPMAurora kinase A2.7.11.10.442
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.442
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2jd0NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.442
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.442
2pym1UNGag-Pol polyprotein3.4.23.160.442
2qd6065Gag-Pol polyprotein3.4.23.160.442
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.442
2vcmM11Isopenicillin N synthase1.21.3.10.442
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.442
2y0mACOHistone acetyltransferase KAT8/0.442
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
3bc3OPTCathepsin L13.4.22.150.442
3ekp478Gag-Pol polyprotein3.4.23.160.442
3i2l2NCProtease/0.442
3imxB84Glucokinase2.7.1.20.442
3iw6PP0Mitogen-activated protein kinase 14/0.442
3m8qDJZGag-Pol polyprotein2.7.7.490.442
3rak03ZCyclin-dependent kinase 22.7.11.220.442
3vt9YI4Vitamin D3 receptor/0.442
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.442
4f6xZYLDehydrosqualene synthase/0.442
4la0198Serum albumin/0.442
4njvRITProtease/0.442
5itzLOCTubulin beta-2B chain/0.442
5upjUINGag-Pol polyprotein/0.442
5g53NECAdenosine receptor A2a/0.442
1grrCLCChloramphenicol 3-O phosphotransferase2.7.10.441
1mrxK57Gag-Pol polyprotein3.4.23.160.441
1sdvMK1Gag-Pol polyprotein3.4.23.160.441
1uydPU8Heat shock protein HSP 90-alpha/0.441
1ybmNAPUncharacterized protein At5g02240/0.441
2bpxMK1Gag-Pol polyprotein3.4.23.160.441
2nnhREACytochrome P450 2C8/0.441
2np7NEAModification methylase TaqI2.1.1.720.441
2rkfAB1Pol protein/0.441
2xszATPRuvB-like 23.6.4.120.441
3a1l2CCCytochrome P450/0.441
3bi6396Wee1-like protein kinase2.7.10.20.441
3bva2NCGag-Pol polyprotein3.4.23.160.441
3fln3FNMitogen-activated protein kinase 14/0.441
3flzFLZMitogen-activated protein kinase 14/0.441
3fmkFMKMitogen-activated protein kinase 14/0.441
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.441
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.441
3kfr3TLGag-Pol polyprotein/0.441
3mxdK53Gag-Pol polyprotein3.4.23.160.441
3o9aK14Pol polyprotein/0.441
3ruqADPChaperonin/0.441
3stuDK3Methylketone synthase I/0.441
3vt3VDXVitamin D3 receptor/0.441
3zhzFM71-deoxy-D-xylulose 5-phosphate reductoisomerase/0.441
4ag8AXIVascular endothelial growth factor receptor 22.7.10.10.441
4bfvZVVPantothenate kinase2.7.1.330.441
4do30LAFatty-acid amide hydrolase 13.5.1.990.441
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.441
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.441
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.441
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.441
1daz0Q4Gag-Pol polyprotein3.4.23.160.440
1eupASD6-deoxyerythronolide B hydroxylase/0.440
1g38NEAModification methylase TaqI2.1.1.720.440
1hsgMK1Gag-Pol polyprotein/0.440
1hvyD16Thymidylate synthase2.1.1.450.440
1hxwRITGag-Pol polyprotein/0.440
1j4jACOAcetyltransferase2.3.10.440
1jomFFODihydrofolate reductase1.5.1.30.440
1muiAB1Protease/0.440
1rl8RITGag-Pol polyprotein3.4.23.160.440
1uzwCDHIsopenicillin N synthase1.21.3.10.440
2nnkROCProtease/0.440
2qi6MZ8Gag-Pol polyprotein/0.440
2qo7ANPEphrin type-A receptor 32.7.10.10.440
2xyeCXGGag-Pol polyprotein/0.440
2xytTC9Soluble acetylcholine receptor/0.440
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.440
3dcrKVSProtease/0.440
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
3djkG55Gag-Pol polyprotein3.4.23.160.440
3el4ROCGag-Pol polyprotein3.4.23.160.440
3el51UNGag-Pol polyprotein/0.440
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.440
3otxAP5Adenosine kinase, putative/0.440
3p6oETGCamphor 5-monooxygenase1.14.15.10.440
3tz3B36Acetyl-CoA carboxylase/0.440
3uhl2NCGag-Pol polyprotein3.4.23.160.440
3vryB43Tyrosine-protein kinase HCK2.7.10.20.440
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.440
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4izy1J2Mitogen-activated protein kinase 82.7.11.240.440
4knzCB3Thymidylate synthase/0.440
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.440
4lx9ACON-alpha-acetyltransferase2.3.10.440
4phlPILPhosphodiesterase/0.440
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.440
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
5ifyUMPGlucose-1-phosphate thymidylyltransferase/0.440