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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.11.000
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.732
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.640
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.636
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.633
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.630
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.629
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.626
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.620
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.620
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.617
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.617
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.616
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.613
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.605
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.604
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.596
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.596
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.594
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.593
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.592
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.591
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.591
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.586
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.580
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.580
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.580
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.579
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.578
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.576
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.572
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.571
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.569
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.564
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.561
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.560
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.559
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.555
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.553
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.549
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.548
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.545
3umw596Serine/threonine-protein kinase pim-12.7.11.10.538
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.538
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.537
3iw4LW4Protein kinase C alpha type2.7.11.130.537
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.537
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.537
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.532
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.530
4dymIYZActivin receptor type-12.7.11.300.526
2jedLG8Protein kinase C theta type2.7.11.130.520
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.519
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.519
4othDRNSerine/threonine-protein kinase N1/0.519
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.513
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.513
4bgg844Activin receptor type-12.7.11.300.511
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.510
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.510
1xjdSTUProtein kinase C theta type2.7.11.130.506
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.506
4jq8KJ8Epidermal growth factor receptor2.7.10.10.501
1wvxBD4Death-associated protein kinase 12.7.11.10.497
5av2KMPDeath-associated protein kinase 12.7.11.10.497
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.495
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.491
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.490
1yvj4STTyrosine-protein kinase JAK32.7.10.20.490
1oiyN41Cyclin-dependent kinase 22.7.11.220.489
2ckeIQUDeath-associated protein kinase 2/0.489
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.489
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.488
3oom507Activin receptor type-12.7.11.300.487
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.487
4i22IREEpidermal growth factor receptor2.7.10.10.487
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3a4pDFQHepatocyte growth factor receptor2.7.10.10.485
3mtfA3FActivin receptor type-12.7.11.300.485
4bchT7ZCyclin-dependent kinase 92.7.11.220.485
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.485
1aq1STUCyclin-dependent kinase 22.7.11.220.484
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.484
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.484
4gg70J8Hepatocyte growth factor receptor2.7.10.10.484
4gmy0X5Tyrosine-protein kinase JAK2/0.484
4riyADPEpidermal growth factor receptor2.7.10.10.484
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.483
4bbe3O4Tyrosine-protein kinase JAK2/0.483
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.482
1pkdUCNCyclin-dependent kinase 22.7.11.220.482
3ormAGSSerine/threonine protein kinase/0.482
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.482
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.481
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.481
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.481
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.481
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.480
3mvl38PMitogen-activated protein kinase 14/0.480
4grb0XGCasein kinase II subunit alpha2.7.11.10.480
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.480
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.479
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.478
2j0k4STFocal adhesion kinase 12.7.10.20.478
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.478
3u4uLNHCasein kinase II subunit alpha2.7.11.10.478
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.478
1oi9N20Cyclin-dependent kinase 22.7.11.220.477
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.477
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.477
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.477
2pvnP63Casein kinase II subunit alpha2.7.11.10.476
2xikJ60Serine/threonine-protein kinase 252.7.11.10.476
3gubGUBDeath-associated protein kinase 12.7.11.10.476
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.476
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.476
4c4h7RODual specificity protein kinase TTK2.7.12.10.476
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.476
2wihP48Cyclin-dependent kinase 22.7.11.220.475
4qmySTUSerine/threonine-protein kinase 242.7.11.10.475
4yuqKS1Calmodulin-like domain protein kinase/0.475
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.475
1h1s4SPCyclin-dependent kinase 22.7.11.220.474
3bqr4RBDeath-associated protein kinase 3/0.474
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.474
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.473
2q9fC3SCholesterol 24-hydroxylase/0.473
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.473
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.473
1ywrLI9Mitogen-activated protein kinase 14/0.472
3vt8YI3Vitamin D3 receptor/0.472
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.471
3be9P04Casein kinase II subunit alpha2.7.11.10.471
3du8553Glycogen synthase kinase-3 beta2.7.11.260.471
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.471
4fob0USALK tyrosine kinase receptor2.7.10.10.471
4iaq2GM5-hydroxytryptamine receptor 1B/0.471
4jr3KJREpidermal growth factor receptor2.7.10.10.471
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.470
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.470
5auwQUEDeath-associated protein kinase 12.7.11.10.470
1zys199Serine/threonine-protein kinase Chk12.7.11.10.469
2i0ePDSProtein kinase C beta type2.7.11.130.469
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.469
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.469
4dgnLU2Casein kinase II subunit alpha2.7.11.10.469
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.469
3uyt0CKCasein kinase I isoform delta2.7.11.10.468
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.468
4c4jX21Dual specificity protein kinase TTK2.7.12.10.468
1eh4IC1Casein kinase I homolog 12.7.11.10.467
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.467
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.467
2pvlP55Casein kinase II subunit alpha2.7.11.10.467
3bu5ATPInsulin receptor2.7.10.10.467
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.467
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4jia1K3Tyrosine-protein kinase JAK2/0.467
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.467
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.466
3q9xEMOCasein kinase II subunit alpha2.7.11.10.466
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.466
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.466
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.465
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.465
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.465
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.465
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4kbk1QGCasein kinase I isoform delta2.7.11.10.465
1bygSTUTyrosine-protein kinase CSK/0.464
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.464
2etm7PYFocal adhesion kinase 12.7.10.20.464
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.464
4ez50RSCyclin-dependent kinase 62.7.11.220.464
4hvi19STyrosine-protein kinase JAK32.7.10.20.464
4ib4ERM5-hydroxytryptamine receptor 2B/0.464
2uxpCLMHTH-type transcriptional regulator TtgR/0.463
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.463
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1qxlFR8Adenosine deaminase3.5.4.40.462
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.462
2itqITQEpidermal growth factor receptor2.7.10.10.462
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.462
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.462
4wboANWRhodopsin kinase/0.462
2hog710Serine/threonine-protein kinase Chk12.7.11.10.461
2iw84SPCyclin-dependent kinase 22.7.11.220.461
2izrBRKCasein kinase I isoform gamma-32.7.11.10.461
3mdvCL6Cholesterol 24-hydroxylase/0.461
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.461
3zh8C58Protein kinase C iota type2.7.11.130.461
4b99R4LMitogen-activated protein kinase 72.7.11.240.461
4gg50J3Hepatocyte growth factor receptor2.7.10.10.461
4j95ACPFibroblast growth factor receptor 2/0.461
5cvhADPCasein kinase II subunit alpha2.7.11.10.461
1k7fIAVTryptophan synthase alpha chain/0.460
2itpAEEEpidermal growth factor receptor2.7.10.10.460
2p33J07Mitogen-activated protein kinase 102.7.11.240.460
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.460
2ittAEEEpidermal growth factor receptor2.7.10.10.459
2om9AJAPeroxisome proliferator-activated receptor gamma/0.459
2x1nX1NCyclin-dependent kinase 22.7.11.220.459
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.459
3zxtACPDeath-associated protein kinase 12.7.11.10.459
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.459
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.458
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2b52D42Cyclin-dependent kinase 22.7.11.220.458
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.458
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.458
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.458
3gc9B45Mitogen-activated protein kinase 112.7.11.240.458
3oroAGSSerine/threonine protein kinase/0.458
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.458
3pe2E1BCasein kinase II subunit alpha2.7.11.10.458
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.458
4hni16WCasein kinase I isoform epsilon2.7.11.10.458
4iarERM5-hydroxytryptamine receptor 1B/0.458
4ix6ADPUncharacterized protein/0.458
4qmzB49Serine/threonine-protein kinase 242.7.11.10.458
1kkq471Peroxisome proliferator-activated receptor alpha/0.457
2izsBRQCasein kinase I isoform gamma-32.7.11.10.457
2znq401Peroxisome proliferator-activated receptor delta/0.457
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3w33W19Epidermal growth factor receptor2.7.10.10.457
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.456
2chlDKICasein kinase I isoform gamma-32.7.11.10.456
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.456
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.456
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
4f630S7Fibroblast growth factor receptor 1/0.456
4g1wG1WMitogen-activated protein kinase 82.7.11.240.456
4hgt15GCasein kinase I isoform delta2.7.11.10.456
4nks2M2Fibroblast growth factor receptor 1/0.456
5auxKMPDeath-associated protein kinase 12.7.11.10.456
1lp4ANPCasein kinase II subunit alpha2.7.11.10.455
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.455
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2j0m4STFocal adhesion kinase 12.7.10.20.455
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.455
3lltANPProtein serine/threonine kinase-1/0.455
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.455
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.455
4hnf16WCasein kinase I isoform delta2.7.11.10.455
1m17AQ4Epidermal growth factor receptor2.7.10.10.454
1oiuN76Cyclin-dependent kinase 22.7.11.220.454
1zeoC01Peroxisome proliferator-activated receptor gamma/0.454
3r9dX6BCyclin-dependent kinase 22.7.11.220.454
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.454
4c4g7RODual specificity protein kinase TTK2.7.12.10.454
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.454
4g170VNCasein kinase I isoform gamma-32.7.11.10.454
4o0wADNAurora kinase A2.7.11.10.454
5e8wSTUTGF-beta receptor type-12.7.11.300.454
1e9hINRCyclin-dependent kinase 22.7.11.220.453
2vu3LZECyclin-dependent kinase 22.7.11.220.453
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.453
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.453
2yaaATPDeath-associated protein kinase 2/0.453
3hllI45Mitogen-activated protein kinase 14/0.453
4ewqMWLMitogen-activated protein kinase 14/0.453
4ic7ANPMitogen-activated protein kinase 72.7.11.240.453
4nc3ERM5-hydroxytryptamine receptor 2B/0.453
5cu6ATPCasein kinase II subunit alpha2.7.11.10.453
1bsvNDPGDP-L-fucose synthase/0.452
1u54ACPActivated CDC42 kinase 1/0.452
2c7xNRBCytochrome P450 monooxygenase PikC/0.452
2cchATPCyclin-dependent kinase 22.7.11.220.452
2h96893Mitogen-activated protein kinase 82.7.11.240.452
2zjwREFCasein kinase II subunit alpha2.7.11.10.452
3a60STURibosomal protein S6 kinase beta-12.7.11.10.452
3at4CCKCasein kinase II subunit alpha2.7.11.10.452
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3l0lHC3Nuclear receptor ROR-gamma/0.452
3nga3NGCasein kinase II subunit alpha2.7.11.10.452
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.452
4bcqTJFCyclin-dependent kinase 22.7.11.220.452
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.452
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.452
4hvg19QTyrosine-protein kinase JAK32.7.10.20.452
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.452
4jq7KJQEpidermal growth factor receptor2.7.10.10.452
1bxoPP7Penicillopepsin-13.4.23.200.451
1dawANPCasein kinase II subunit alpha2.7.11.10.451
1jklANPDeath-associated protein kinase 12.7.11.10.451
2bujSTUSerine/threonine-protein kinase 16/0.451
2w05FRTCyclin-dependent kinase 22.7.11.220.451
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.451
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.451
4b7sQLECytochrome P450 monooxygenase PikC/0.451
4h9814QUncharacterized protein/0.451
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
1m2pHNACasein kinase II subunit alpha2.7.11.10.450
2i40BLZCyclin-dependent kinase 22.7.11.220.450
2uzeC95Cyclin-dependent kinase 22.7.11.220.450
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.450
3c50ADPRhodopsin kinase/0.450
3qtuX44Cyclin-dependent kinase 22.7.11.220.450
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.450
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4kb81QNCasein kinase I isoform delta2.7.11.10.450
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.450
5cshATPCasein kinase II subunit alpha2.7.11.10.450
5cvfATPCasein kinase II subunit alpha2.7.11.10.450
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1m13HYFNuclear receptor subfamily 1 group I member 2/0.449
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.449
2c5nCK8Cyclin-dependent kinase 22.7.11.220.449
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.449
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.449
3gxlQIGTGF-beta receptor type-12.7.11.300.449
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3qaiXNNKetohexokinase/0.449
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.449
4wa9AXITyrosine-protein kinase ABL12.7.10.20.449
5av3KMPDeath-associated protein kinase 12.7.11.10.449
1fmjRTLRetinol dehydratase/0.448
1p4fDRGDeath-associated protein kinase 12.7.11.10.448
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.448
2ovhAS0Progesterone receptor/0.448
2w1fL0FAurora kinase A2.7.11.10.448
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.448
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.448
3gc8B45Mitogen-activated protein kinase 112.7.11.240.448
3litE15Protease/0.448
3mtlFEFCyclin-dependent kinase 162.7.11.220.448
3t8oATPRhodopsin kinase/0.448
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4gu610NFocal adhesion kinase 12.7.10.20.448
4kba1QMCasein kinase I isoform delta2.7.11.10.448
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.448
4qmlANPSerine/threonine-protein kinase 242.7.11.10.448
4xlvACPInsulin receptor2.7.10.10.448
2ijmADPFocal adhesion kinase 12.7.10.20.447
2j0j4STFocal adhesion kinase 12.7.10.20.447
2uzlC94Cyclin-dependent kinase 22.7.11.220.447
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.447
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.447
3gu83GUDeath-associated protein kinase 12.7.11.10.447
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.447
3vt9YI4Vitamin D3 receptor/0.447
3w2sW2REpidermal growth factor receptor2.7.10.10.447
4anmWULCasein kinase II subunit alpha2.7.11.10.447
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4o5qFADAlkyl hydroperoxide reductase subunit F1.8.10.447
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1ke7LS3Cyclin-dependent kinase 22.7.11.220.446
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.446
2pwlACPFibroblast growth factor receptor 2/0.446
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.446
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.446
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.446
3gu6ADPDeath-associated protein kinase 12.7.11.10.446
3kvxFMYMitogen-activated protein kinase 102.7.11.240.446
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.446
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.446
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.446
1g5sI17Cyclin-dependent kinase 22.7.11.220.445
1oguST8Cyclin-dependent kinase 22.7.11.220.445
1u4dDBQActivated CDC42 kinase 1/0.445
1zgaHMKIsoflavone 4'-O-methyltransferase/0.445
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.445
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2wecPP5Penicillopepsin-13.4.23.200.445
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.445
3kf7L9GMitogen-activated protein kinase 14/0.445
3l8p0CEAngiopoietin-1 receptor2.7.10.10.445
3linE13Protease/0.445
3mqe416Prostaglandin G/H synthase 21.14.99.10.445
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.445
3vewADPnebramycin 5' synthase6.1.2.20.445
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.445
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.445
3zze6XPHepatocyte growth factor receptor2.7.10.10.445
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4erwSTUCyclin-dependent kinase 22.7.11.220.445
4fz60VGTyrosine-protein kinase SYK2.7.10.20.445
4gub0Y4Casein kinase II subunit alpha2.7.11.10.445
4wsqKSAAP2-associated protein kinase 12.7.11.10.445
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.445
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1pmn984Mitogen-activated protein kinase 102.7.11.240.444
1umlFR4Adenosine deaminase3.5.4.40.444
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.444
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.444
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.444
3blrCPBCyclin-dependent kinase 92.7.11.220.444
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.444
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.444
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
3tmz06XCytochrome P450 2B41.14.14.10.444
3vetADPnebramycin 5' synthase6.1.2.20.444
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.444
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.444
4e730NRMitogen-activated protein kinase 82.7.11.240.444
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4jrvKJVEpidermal growth factor receptor2.7.10.10.444
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.444
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1h1r6CPCyclin-dependent kinase 22.7.11.220.443
1k6tXN1Gag-Pol polyprotein3.4.23.160.443
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1y0s331Peroxisome proliferator-activated receptor delta/0.443
1zhwHC2Oxysterol-binding protein homolog 4/0.443
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.443
2pulACPMethylthioribose kinase2.7.1.1000.443
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.443
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.443
3a7jADPSerine/threonine-protein kinase 242.7.11.10.443
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.443
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.443
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3sheI85MAP kinase-activated protein kinase 32.7.11.10.443
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4fmqANPMitogen-activated protein kinase 12.7.11.240.443
4fnyI3KALK tyrosine kinase receptor2.7.10.10.443
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.443
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.443
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.443
4fyn0VETyrosine-protein kinase SYK2.7.10.20.443
4nk92K5Fibroblast growth factor receptor 1/0.443
5auvAGIDeath-associated protein kinase 12.7.11.10.443
1ke6LS2Cyclin-dependent kinase 22.7.11.220.442
1ppjANYCytochrome b/0.442
1zhzERGOxysterol-binding protein homolog 4/0.442
2q59240Peroxisome proliferator-activated receptor gamma/0.442
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.442
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.442
3ddpRC8Cyclin-dependent kinase 22.7.11.220.442
3nszANPCasein kinase II subunit alpha2.7.11.10.442
3vryB43Tyrosine-protein kinase HCK2.7.10.20.442
3vt7VDXVitamin D3 receptor/0.442
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.442
4c62XWWTyrosine-protein kinase JAK2/0.442
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.442
4g160VMCasein kinase I isoform gamma-32.7.11.10.442
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4qmpDKISerine/threonine-protein kinase 242.7.11.10.442
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.442
5f0a1FBcGMP-dependent protein kinase, putative/0.442
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1k6cMK1Gag-Pol polyprotein3.4.23.160.441
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.441
1s3wTQTDihydrofolate reductase1.5.1.30.441
2pvhP19Casein kinase II subunit alpha2.7.11.10.441
3cv9VDXVitamin D3 dihydroxylase/0.441
3rpv26ZCyclin-dependent kinase 22.7.11.220.441
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.441
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4hvh19RTyrosine-protein kinase JAK32.7.10.20.441
1gih1PUCyclin-dependent kinase 22.7.11.220.440
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.440
2fvdLIACyclin-dependent kinase 22.7.11.220.440
2hw2RFPRifampin ADP-ribosyl transferase/0.440
2j0lANPFocal adhesion kinase 12.7.10.20.440
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.440
2xb7GUIALK tyrosine kinase receptor2.7.10.10.440
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.440
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.440
4r21STRCytochrome P450 family 17 polypeptide 2/0.440
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440