Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ek2 | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ek2 | SAH | Diphthine synthase | / | 1.000 | |
| 2z6r | SAH | Diphthine synthase | / | 0.822 | |
| 2e17 | SAH | Diphthine synthase | / | 0.799 | |
| 2e4n | SAH | Diphthine synthase | / | 0.792 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.782 | |
| 2owk | SAH | Diphthine synthase | / | 0.779 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.767 | |
| 2hut | SAH | Diphthine synthase | / | 0.766 | |
| 2emu | SAH | Diphthine synthase | / | 0.761 | |
| 2owu | SAH | Diphthine synthase | / | 0.752 | |
| 2ehl | SAH | Diphthine synthase | / | 0.743 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.740 | |
| 2huv | SAH | Diphthine synthase | / | 0.738 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.733 | |
| 2emr | SAH | Diphthine synthase | / | 0.733 | |
| 2eeq | SAH | Diphthine synthase | / | 0.728 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.728 | |
| 1wng | SAH | Diphthine synthase | / | 0.724 | |
| 2dek | SAH | Diphthine synthase | / | 0.724 | |
| 2e15 | SAH | Diphthine synthase | / | 0.723 | |
| 2eld | SAH | Diphthine synthase | / | 0.723 | |
| 2e8r | SAH | Diphthine synthase | / | 0.722 | |
| 2el0 | SAH | Diphthine synthase | / | 0.718 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.715 | |
| 2el3 | SAH | Diphthine synthase | / | 0.715 | |
| 2dsg | SAH | Diphthine synthase | / | 0.712 | |
| 2e07 | SAH | Diphthine synthase | / | 0.709 | |
| 2p6l | SAH | Diphthine synthase | / | 0.708 | |
| 2dsi | SAH | Diphthine synthase | / | 0.707 | |
| 2hux | SAH | Diphthine synthase | / | 0.699 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.693 | |
| 2e8q | SAH | Diphthine synthase | / | 0.690 | |
| 2owg | SAH | Diphthine synthase | / | 0.690 | |
| 2eni | SAH | Diphthine synthase | / | 0.687 | |
| 2p5f | SAH | Diphthine synthase | / | 0.685 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.681 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.681 | |
| 2e8s | SAH | Diphthine synthase | / | 0.680 | |
| 2dxw | SAH | Diphthine synthase | / | 0.678 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.676 | |
| 2pci | SAH | Diphthine synthase | / | 0.676 | |
| 2e8h | SAH | Diphthine synthase | / | 0.673 | |
| 2huq | SAH | Diphthine synthase | / | 0.667 | |
| 2ejj | SAH | Diphthine synthase | / | 0.666 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.665 | |
| 2pcm | SAH | Diphthine synthase | / | 0.664 | |
| 2en5 | SAH | Diphthine synthase | / | 0.660 | |
| 2dxv | SAH | Diphthine synthase | / | 0.658 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.658 | |
| 2ele | SAH | Diphthine synthase | / | 0.657 | |
| 1vce | SAH | Diphthine synthase | / | 0.656 | |
| 2pca | SAH | Diphthine synthase | / | 0.651 | |
| 2p5c | SAH | Diphthine synthase | / | 0.650 | |
| 2p9d | SAH | Diphthine synthase | / | 0.650 | |
| 2ejk | SAH | Diphthine synthase | / | 0.645 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.645 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.642 | |
| 2e16 | SAH | Diphthine synthase | / | 0.637 | |
| 2p6d | SAH | Diphthine synthase | / | 0.635 | |
| 2eka | SAH | Diphthine synthase | / | 0.633 | |
| 2p6k | SAH | Diphthine synthase | / | 0.632 | |
| 2egl | SAH | Diphthine synthase | / | 0.630 | |
| 2owv | SAH | Diphthine synthase | / | 0.630 | |
| 2p2x | SAH | Diphthine synthase | / | 0.629 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.628 | |
| 2pcg | SAH | Diphthine synthase | / | 0.628 | |
| 2p6i | SAH | Diphthine synthase | / | 0.626 | |
| 2dxx | SAH | Diphthine synthase | / | 0.625 | |
| 2e7r | SAH | Diphthine synthase | / | 0.625 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.621 | |
| 2pch | SAH | Diphthine synthase | / | 0.618 | |
| 2egs | SAH | Diphthine synthase | / | 0.599 | |
| 2e08 | SAH | Diphthine synthase | / | 0.598 | |
| 2pck | SAH | Diphthine synthase | / | 0.594 | |
| 2dsh | SAH | Diphthine synthase | / | 0.580 | |
| 2owf | SAH | Diphthine synthase | / | 0.568 | |
| 2ejz | SAH | Diphthine synthase | / | 0.553 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.534 | |
| 2egb | SAH | Diphthine synthase | / | 0.530 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.509 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.500 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.494 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.494 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.487 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.486 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.484 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.481 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.478 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.477 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.477 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.477 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.476 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.475 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.475 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.474 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.473 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.473 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.472 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.472 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.472 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.472 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.471 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.470 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.470 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.470 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.470 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.469 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.469 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.468 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.468 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.467 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.466 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.466 | |
| 5dp2 | NAP | CurF | / | 0.466 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.465 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.465 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.465 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.465 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.465 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.464 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.464 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.464 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.464 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.464 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.464 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.464 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.464 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.463 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.463 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.463 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.462 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.462 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.462 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.461 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.461 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.461 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.461 | |
| 4ohv | ANP | Protein clpf-1 | / | 0.461 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.461 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.460 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 2y3s | TIR | TamL | / | 0.460 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.460 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.460 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.460 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.459 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.458 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.458 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.458 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.457 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.457 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.457 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.457 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.457 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.457 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.456 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.456 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.456 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.456 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.455 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.455 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.455 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.455 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.454 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.454 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.454 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.454 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.454 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.454 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.454 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.454 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.454 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.453 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.453 | |
| 1zio | AP5 | Adenylate kinase | / | 0.453 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.453 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.453 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.452 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.452 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.452 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.452 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.452 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.452 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.452 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.452 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.452 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.452 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.451 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.451 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.451 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.451 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.451 | |
| 3wag | TYD | Glycosyltransferase | / | 0.451 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.450 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.450 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.450 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.450 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.450 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.450 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.450 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.449 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.449 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.449 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.449 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.449 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.449 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.449 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.448 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.448 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.448 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.448 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.448 | |
| 4yqf | GDP | Septin-9 | / | 0.448 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.447 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.447 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 5a3b | APR | SIR2 family protein | / | 0.447 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.447 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.446 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.446 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.446 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.446 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.446 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.445 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.445 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.445 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.445 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.445 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.445 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.445 | |
| 4kb9 | G79 | Protease | / | 0.445 | |
| 4qec | NAP | ElxO | / | 0.445 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.444 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.444 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.444 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.444 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.444 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.444 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.444 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.444 | |
| 4xr9 | NAD | CalS8 | / | 0.444 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1eio | GCH | Gastrotropin | / | 0.443 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.443 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.443 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.443 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.443 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.443 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.443 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4jxr | ACO | Acetyltransferase | / | 0.443 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.442 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.442 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.442 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.442 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.442 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.442 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4a4q | UX9 | Pol protein | / | 0.442 | |
| 4jld | ADP | Adenylate kinase | / | 0.442 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.441 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.441 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.441 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.441 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.440 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.440 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.440 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.440 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.440 | |
| 2vwh | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.440 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.440 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.440 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.440 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.440 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.440 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.440 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.440 |