Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5ez7 FAD Probable FAD-dependent oxidoreductase PA4991

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
5ez7 FADProbable FAD-dependent oxidoreductase PA4991 / 1.300
3m0o FADMonomeric sarcosine oxidase 1.5.3.1 0.866
5i39 FADL-amino acid deaminase / 0.844
1kif FADD-amino-acid oxidase 1.4.3.3 0.843
3dme FADPutative conserved exported protein / 0.836
3ad9 FADSubunit beta of sarcosine oxidase / 0.834
3m13 FADMonomeric sarcosine oxidase 1.5.3.1 0.827
4x9m FADUncharacterized protein MG039 homolog / 0.822
4ysh FADGlycine oxidase / 0.821
3znp FADD-amino-acid oxidase 1.4.3.3 0.815
1ryi FADGlycine oxidase 1.4.3.19 0.810
4opd FDAConserved Archaeal protein / 0.803
3gsi FADDimethylglycine oxidase 1.5.3.10 0.798
1ng4 FADGlycine oxidase 1.4.3.19 0.793
2qcu FADAerobic glycerol-3-phosphate dehydrogenase 1.1.5.3 0.793
4yjd FADD-amino-acid oxidase 1.4.3.3 0.792
3cuk FADD-amino-acid oxidase 1.4.3.3 0.789
4x9n FADUncharacterized protein MG039 homolog / 0.787
2du8 FADD-amino-acid oxidase 1.4.3.3 0.785
3axb FADPutative oxidoreductase / 0.782
4opc FDAConserved Archaeal protein / 0.779
1qo8 FADFumarate reductase flavoprotein subunit / 0.777
1c0k FADD-amino-acid oxidase 1.4.3.3 0.776
4xwz FADFructosyl amine:oxygen oxidoreductase / 0.772
5hxw FADL-amino acid deaminase / 0.772
1c0l FADD-amino-acid oxidase 1.4.3.3 0.769
1knp FADL-aspartate oxidase 1.4.3.16 0.768
3if9 FADGlycine oxidase 1.4.3.19 0.760
3pl8 FADPyranose 2-oxidase / 0.760
3vqr FADPutative oxidoreductase / 0.760
4opi FDAConserved Archaeal protein / 0.759
1knr FADL-aspartate oxidase 1.4.3.16 0.757
4gdp FADPolyamine oxidase FMS1 / 0.757
4opt FDAConserved Archaeal protein / 0.757
4udq FAD5-(hydroxymethyl)furfural oxidase / 0.757
3ka7 FADPutative oxidoreductase / 0.753
1tdo FADL-amino-acid oxidase 1.4.3.2 0.750
4mih FADPyranose 2-oxidase 1.1.3.10 0.750
3cnt FADPolyamine oxidase FMS1 / 0.745
3rp8 FADFAD-dependent urate hydroxylase / 0.742
4c3y FAD3-ketosteroid dehydrogenase / 0.741
1rsg FADPolyamine oxidase FMS1 / 0.738
2rgh FADAlpha-Glycerophosphate Oxidase / 0.738
4kx6 FADFumarate reductase flavoprotein subunit 1.3.5.4 0.738
2c3c FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.737
1d4c FADFumarate reductase flavoprotein subunit 1.3.5.4 0.735
3lov FADProtoporphyrinogen oxidase / 0.735
4bk3 FADProbable salicylate monooxygenase / 0.735
4rsl FADFructosyl peptide oxidase / 0.735
1i8t FADUDP-galactopyranose mutase 5.4.99.9 0.734
3q9t FAYUncharacterized protein / 0.733
1f8r FADL-amino-acid oxidase 1.4.3.2 0.731
1ng3 FADGlycine oxidase 1.4.3.19 0.731
3pvc FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.731
1d7l RFLp-hydroxybenzoate hydroxylase / 0.730
2gh5 FADGlutathione reductase, mitochondrial 1.8.1.7 0.730
3bi5 FADPolyamine oxidase FMS1 / 0.730
2ard FDAFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.729
3sfd FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 0.729
1f8s FADL-amino-acid oxidase 1.4.3.2 0.728
2z6d FMNPhototropin-2 2.7.11.1 0.728
3sfe FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 0.726
1nhr FADNADH peroxidase 1.11.1.1 0.725
1h7w FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.722
1y56 FAD382aa long hypothetical sarcosine oxidase / 0.722
3atr FDAConserved Archaeal protein / 0.722
3sgl FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.722
4opl FDAConserved Archaeal protein / 0.722
1f8w FADNADH peroxidase 1.11.1.1 0.721
2fja FADAdenylylsulfate reductase, subunit A (AprA) / 0.720
2ign FADPyranose 2-oxidase / 0.720
2tpr FADTrypanothione reductase 1.8.1.12 0.720
4wct FADFructosyl amine:oxygen oxidoreductase / 0.720
1gte FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.719
4bjz FADProbable salicylate monooxygenase / 0.719
3k4n FADPyranose 2-oxidase / 0.718
1gth FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.717
1jnr FADAdenylylsulfate reductase, subunit A (AprA) / 0.717
4j36 FADKynurenine 3-monooxygenase / 0.716
2i0z FADNAD(FAD)-utilizing dehydrogenases / 0.715
3aeb FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 0.714
1zx9 FADMercuric reductase 1.16.1.1 0.713
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.713
4qi4 FADCellobiose dehydrogenase / 0.713
5fs7 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.712
2c3d FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.711
4bk2 FADProbable salicylate monooxygenase / 0.711
4qi5 FADCellobiose dehydrogenase / 0.711
5hsa FASAlcohol oxidase 1 1.1.3.13 0.710
1sez FADProtoporphyrinogen oxidase, mitochondrial 1.3.3.4 0.706
3k4c FADPyranose 2-oxidase / 0.706
4ynt FDAGlucose oxidase, putative / 0.706
3fmw FADOxygenase / 0.705
4kuk RBFPutative blue-light photoreceptor / 0.704
1tdn FADL-amino-acid oxidase 1.4.3.2 0.703
3r9u FADThioredoxin reductase / 0.702
3dk4 FADGlutathione reductase, mitochondrial 1.8.1.7 0.701
4j57 FADThioredoxin reductase 2 1.8.1.9 0.701
1reo FADL-amino-acid oxidase 1.4.3.2 0.700
3cox FADCholesterol oxidase 1.1.3.6 0.700
1efv FADElectron transfer flavoprotein subunit alpha, mitochondrial / 0.699
1jeh FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.699
2gew FADCholesterol oxidase 1.1.3.6 0.697
4cy8 FDA2-hydroxybiphenyl-3-monooxygenase / 0.697
1nhp FADNADH peroxidase 1.11.1.1 0.696
2y48 FADLysine-specific histone demethylase 1A 1 0.696
3qvr FADGlucose oxidase 1.1.3.4 0.696
5l3d FADLysine-specific histone demethylase 1A 1 0.696
1nhs FADNADH peroxidase 1.11.1.1 0.695
1onf FADGlutathione reductase 1.8.1.7 0.694
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.693
2yqu FADDihydrolipoyl dehydrogenase / 0.693
4yry FADGlutamate synthase, beta subunit / 0.693
1h83 FADPolyamine oxidase 1.5.3.14 0.692
4cnj FADL-amino acid oxidase / 0.691
2isl FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.690
3gmb FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase / 0.690
3lsi FADPyranose 2-oxidase / 0.690
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.690
3we0 FADLysine 2-monooxygenase / 0.690
4at0 FADPossible succinate dehydrogenase / 0.690
4cnk FADL-amino acid oxidase / 0.690
5er0 FADUncharacterized NAD(FAD)-dependent dehydrogenase / 0.690
4opu FDAConserved Archaeal protein / 0.689
1ger FADGlutathione reductase 1.8.1.7 0.688
4c3x FAD3-ketosteroid dehydrogenase / 0.688
2gr3 FADFerredoxin reductase / 0.687
2jb2 FADL-amino acid oxidase / 0.687
3mzi FMNActivator of photopigment and puc expression / 0.687
3ukk FDAUDP-galactopyranose mutase / 0.687
4gut FADLysine-specific histone demethylase 1B 1 0.687
4mok FADPyranose 2-oxidase / 0.687
1joa FADNADH peroxidase 1.11.1.1 0.686
1k0j FADp-hydroxybenzoate hydroxylase / 0.686
1npx FADNADH peroxidase 1.11.1.1 0.686
2dw4 FADLysine-specific histone demethylase 1A 1 0.686
3qvp FADGlucose oxidase 1.1.3.4 0.686
1cqx FADFlavohemoprotein / 0.685
1i0s FMNFerric-chelate reductase (NAD(P)H) / 0.685
2qae FADDihydrolipoyl dehydrogenase 1.8.1.4 0.685
3ic9 FADPutative dihydrolipoamide dehydrogenase / 0.685
4xbf FADLysine-specific histone demethylase 1A 1 0.685
1dxo FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.684
1yy5 FADPolyamine oxidase FMS1 / 0.683
2jk6 FADTrypanothione reductase / 0.683
3gyi FADCholesterol oxidase 1.1.3.6 0.683
3gyj FADCholesterol oxidase 1.1.3.6 0.683
4nev FADTrypanothione reductase / 0.683
1bzl FADTrypanothione reductase 1.8.1.12 0.682
2bab FADPutative aminooxidase / 0.682
2e1m FADL-glutamate oxidase / 0.682
3ntd FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.682
3zdn FADMonoamine oxidase N 1.4.3.4 0.682
4j33 FADKynurenine 3-monooxygenase / 0.682
2fjb SFDAdenylylsulfate reductase, subunit A (AprA) / 0.681
3dk8 FADGlutathione reductase, mitochondrial 1.8.1.7 0.681
4ech FADPolyamine oxidase FMS1 / 0.681
4xwr FADCholesterol oxidase 1.1.3.6 0.681
2vou FAD2,6-dihydroxypyridine 3-monooxygenase 1.14.13.10 0.680
3nyc FADFAD-dependent catabolic D-arginine dehydrogenase DauA / 0.680
4u2t FADCholesterol oxidase 1.1.3.6 0.680
1jnz FADAdenylylsulfate reductase, subunit A (AprA) / 0.679
1q1r FADPutidaredoxin reductase 1.18.1.5 0.679
2iw5 FADLysine-specific histone demethylase 1A 1 0.679
3ukf FDAUDP-galactopyranose mutase / 0.679
4hb9 FADUncharacterized protein / 0.679
2eq7 FADDihydrolipoyl dehydrogenase / 0.678
4uir FADOleate hydratase 4.2.1.53 0.678
1h81 FADPolyamine oxidase 1.5.3.14 0.677
2vvl FADMonoamine oxidase N 1.4.3.4 0.677
3kpf FADPolyamine oxidase 1.5.3.14 0.677
2fjd SFDAdenylylsulfate reductase, subunit A (AprA) / 0.676
2igo FADPyranose 2-oxidase / 0.676
1dxq FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.675
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.675
1tdk FADL-amino-acid oxidase 1.4.3.2 0.675
3lb8 FADPutidaredoxin reductase 1.18.1.5 0.675
4b1b FADThioredoxin reductase 1.8.1.9 0.675
4opg FDAConserved Archaeal protein / 0.675
1b4v FADCholesterol oxidase 1.1.3.6 0.674
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.674
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.674
1rz0 FADPhenol 2-hydroxylase component B / 0.674
4eep FMNPhototropin-2 2.7.11.1 0.674
3lsh FADPyranose 2-oxidase / 0.673
4hsu FADLysine-specific histone demethylase 1B 1 0.673
5g3t FDAFlavin-dependent L-tryptophan oxidase VioA / 0.673
1grg FADGlutathione reductase, mitochondrial 1.8.1.7 0.672
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.672
1xdi FADNAD(P)H dehydrogenase (quinone) / 0.672
5g3s FDAFlavin-dependent L-tryptophan oxidase VioA / 0.672
2oa1 FADFlavin-dependent tryptophan halogenase RebH 1.14.19.9 0.671
3m12 FADMonomeric sarcosine oxidase 1.5.3.1 0.671
2jae FADL-amino acid oxidase / 0.670
3lsm SFDPyranose 2-oxidase / 0.670
4hh0 FMNAppA protein / 0.670
2v3a FADRubredoxin-NAD(+) reductase 1.18.1.1 0.669
2yr5 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.669
1b8s FADCholesterol oxidase 1.1.3.6 0.668
1gpe FADGlucose oxidase 1.1.3.4 0.668
1ve9 FADD-amino-acid oxidase 1.4.3.3 0.668
2iyg FMNAppA, antirepressor of ppsR, sensor of blue light / 0.668
2q0k FADThioredoxin reductase 1.8.1.9 0.668
3cn8 FADPolyamine oxidase FMS1 / 0.668
3f8d FADNADH oxidase/thioredoxin reductase / 0.668
4f07 FADStyrene monooxygenase component 2 / 0.668
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.667
1n4u FAECholesterol oxidase 1.1.3.6 0.667
2wba FADTrypanothione reductase 1.8.1.12 0.667
3cgc FADCoenzyme A disulfide reductase / 0.667
3cnd FADPolyamine oxidase FMS1 / 0.667
4fwe FADLysine-specific histone demethylase 1B 1 0.667
4fwj FADLysine-specific histone demethylase 1B 1 0.667
4eer FMNPhototropin-2 2.7.11.1 0.666
4hj6 FMNLOV protein / 0.666
1gal FADGlucose oxidase 1.1.3.4 0.665
2cdu FADNADH oxidase / 0.665
2iyi FMNAppA, antirepressor of ppsR, sensor of blue light / 0.665
3cnj FADCholesterol oxidase 1.1.3.6 0.665
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.665
3k7t FAD6-hydroxy-L-nicotine oxidase / 0.665
4qof FMNRibosyldihydronicotinamide dehydrogenase [quinone] / 0.665
2q7v FADThioredoxin reductase / 0.664
3icr FADCoenzyme A disulfide reductase / 0.664
2jb1 FADL-amino acid oxidase / 0.663
1z6l FADPolyamine oxidase FMS1 / 0.662
1zk7 FADMercuric reductase 1.16.1.1 0.662
2pr5 FMNBlue-light photoreceptor / 0.662
3grs FADGlutathione reductase, mitochondrial 1.8.1.7 0.662
1mxt FAECholesterol oxidase 1.1.3.6 0.661
1sbz FMNProbable UbiX-like flavin prenyltransferase / 0.661
2a87 FADThioredoxin reductase 1.8.1.9 0.661
2pd7 FADVivid PAS protein VVD / 0.661
3utg FDAUDP-galactopyranose mutase / 0.661
1n1p FADCholesterol oxidase 1.1.3.6 0.660
1n4v FADCholesterol oxidase 1.1.3.6 0.660
1n4w FADCholesterol oxidase 1.1.3.6 0.660
1xpq FADPolyamine oxidase FMS1 / 0.660
2zzc FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.660
3awi FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 1.5 0.660
1cf3 FADGlucose oxidase 1.1.3.4 0.659
1usc FMNMonooxygenase / 0.659
1yrx FMNAppA protein / 0.659
2bry FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.659
2npx FADNADH peroxidase 1.11.1.1 0.659
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.659
3ics FADCoenzyme A disulfide reductase / 0.659
4eet FMNPhototropin-2 2.7.11.1 0.659
4ocg FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.659
4z26 FADPutative GMC-type oxidoreductase R135 1 0.659
1e1m FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.658
3kve FADL-amino-acid oxidase / 0.658
3qj4 FADRenalase / 0.658
4nwz FADFAD-dependent pyridine nucleotide-disulfide oxidoreductase / 0.658
4xxg FADCholesterol oxidase 1.1.3.6 0.658
5af7 FADAcyl-CoA dehydrogenase / 0.658
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.657
2bkj FMNNADPH-flavin oxidoreductase / 0.657
2oal FADFlavin-dependent tryptophan halogenase RebH 1.14.19.9 0.657
3gdp FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.657
3lad FADDihydrolipoyl dehydrogenase / 0.657
3v76 FDAUncharacterized protein / 0.657
4bv6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.657
4gcm FADThioredoxin reductase 1.8.1.9 0.657
4kuo RBFPutative blue-light photoreceptor / 0.657
4u8o FDAUDP-galactopyranose mutase / 0.657
4ykf FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.657
1eje FMNProtein MTH_152 / 0.656
2e48 FADD-amino-acid oxidase 1.4.3.3 0.656
4i58 FADCyclohexylamine Oxidase / 0.656
4u8n FDAUDP-galactopyranose mutase / 0.656
4wuj FMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy / 0.656
2yg5 FADPutrescine oxidase / 0.655
2yr4 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.655
3djg FADGlutathione reductase, mitochondrial 1.8.1.7 0.655
4m52 FADDihydrolipoyl dehydrogenase 1.8.1.4 0.655
3uth FDAUDP-galactopyranose mutase / 0.654
4c5o FADPutative monooxygenase / 0.654
4gr1 FADGlutathione reductase, mitochondrial 1.8.1.7 0.654
4u2l SFDCholesterol oxidase 1.1.3.6 0.654
2a1t FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.653
2ar8 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.653
2nvk FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.653
2wp5 FADTrypanothione reductase / 0.653
3all FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase / 0.653
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.653
4gur FADLysine-specific histone demethylase 1B 1 0.653
4hhd FMNPhototropin-1 2.7.11.1 0.653
1typ FADTrypanothione reductase 1.8.1.12 0.652
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.652
2qa1 FADPgaE / 0.652
3dk9 FADGlutathione reductase, mitochondrial 1.8.1.7 0.652
3gfx FMNUncharacterized protein / 0.652
3gg0 FMNUncharacterized protein / 0.652
1tde FADThioredoxin reductase 1.8.1.9 0.651
2vyq FADFerredoxin--NADP reductase 1.18.1.2 0.651
4h4z FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.651
4nte FADDepH / 0.651
1k4q FADGlutathione reductase, mitochondrial 1.8.1.7 0.650
1n9n FMNPutative blue light receptor / 0.650
3eo8 FMNPutative nitroreductase / 0.650
4gde FDAUDP-galactopyranose mutase / 0.650
4h2n FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase / 0.650
4jn9 FADDepH / 0.650
4u8k FDAUDP-galactopyranose mutase / 0.650
4wx1 FDAUDP-galactopyranose mutase / 0.650