Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 1.000 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.574 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.553 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.541 | |
| 1pkg | ADP | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.535 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.531 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.526 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.524 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.522 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.521 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.519 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.518 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.515 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.513 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.513 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.511 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.511 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.510 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.508 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.507 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.506 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.506 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.505 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.505 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.503 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.503 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.502 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.502 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.501 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.501 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.500 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.500 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.500 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.500 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.499 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.497 | |
| 1jnk | ANP | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.495 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.495 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.493 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.492 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.492 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.492 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.490 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.490 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.489 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.489 | |
| 2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.487 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.487 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.487 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.486 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.486 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.486 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.486 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.485 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.485 | |
| 1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.484 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.484 | |
| 2pml | ANP | Uncharacterized protein | / | 0.484 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.484 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.484 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.483 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.481 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.481 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.480 | |
| 4jrn | ANP | Rhoptry kinase family protein | / | 0.480 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.479 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.479 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.478 | |
| 1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.478 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.478 | |
| 3zly | YSO | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.478 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.478 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.477 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.477 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.477 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.477 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.476 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.476 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.476 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.476 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.476 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.474 | |
| 4w9w | YDJ | BMP-2-inducible protein kinase | 2.7.11.1 | 0.474 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 3zls | 92P | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.473 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.473 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.473 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.473 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 5eg3 | ACP | Fibroblast growth factor receptor 2 | / | 0.473 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.472 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.472 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.472 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.472 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.472 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.471 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 4ivb | 1J5 | Tyrosine-protein kinase JAK1 | / | 0.471 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.471 | |
| 4o1p | ANP | Ribonuclease L | / | 0.471 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.470 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.470 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.469 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.469 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.469 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.468 | |
| 4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.468 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.468 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.468 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.467 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.467 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 5dmz | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.467 | |
| 5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 0.467 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.466 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.466 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.466 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.466 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.466 | |
| 4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.466 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.465 | |
| 1w0x | OLO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.465 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.465 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.464 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.464 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.464 | |
| 4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.464 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.464 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.464 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.463 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.463 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4nif | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
| 1j1b | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.462 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2o2u | 738 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.462 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.462 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.462 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.462 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.462 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.462 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.462 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.462 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.461 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.461 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.461 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.461 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.461 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.461 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.460 | |
| 1u5r | ATP | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.460 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.460 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.460 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.460 | |
| 4fsu | HK5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.460 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.459 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.459 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.459 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.459 | |
| 3zmm | F9J | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 4eol | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.458 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.458 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.458 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.458 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2zdu | 446 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.457 | |
| 4dee | ADP | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.457 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.457 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.457 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2btr | U73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.456 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.456 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.456 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.455 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.455 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.455 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.455 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.455 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.454 | |
| 3qc9 | ADP | Rhodopsin kinase | / | 0.454 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.454 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.453 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.453 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.453 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.452 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1wvy | STU | Death-associated protein kinase 1 | 2.7.11.1 | 0.452 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.452 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.452 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.452 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.451 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.451 | |
| 4ceg | ADP | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.451 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.450 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.450 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.450 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.450 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.450 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 4jik | 1KO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.449 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.449 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.449 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.449 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.449 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 1ppj | ANY | Cytochrome b | / | 0.448 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.448 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.448 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.447 | |
| 3r8l | Z30 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4bgh | 3I6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.447 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.446 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.446 | |
| 3rpo | 24Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.446 | |
| 4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 5cno | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 5dnr | ATP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3rkb | 12Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.445 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.445 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.445 | |
| 4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 1jkl | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.444 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.444 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.443 | |
| 4riy | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.443 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.443 | |
| 1jkk | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 2c5y | MTW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2uw4 | L15 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.442 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.442 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.442 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2w4j | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.441 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.441 | |
| 3r71 | X86 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.441 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 4nm0 | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.440 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.440 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.440 | |
| 4ivd | 15T | Tyrosine-protein kinase JAK1 | / | 0.440 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
| 5dr2 | ATP | Aurora kinase A | 2.7.11.1 | 0.440 |