Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tn8 | F18 | Cyclin-dependent kinase 9 | 2.7.11.22 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3tn8 | F18 | Cyclin-dependent kinase 9 | 2.7.11.22 | 1.000 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.556 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.549 | |
| 1dm2 | HMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.547 | |
| 3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.540 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.533 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.528 | |
| 3r8z | Z63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.528 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.527 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.527 | |
| 2uzd | C85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.523 | |
| 2euf | LQQ | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.522 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.521 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.520 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.520 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.519 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.517 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.516 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.516 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.513 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.513 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.512 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.512 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.510 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.507 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.507 | |
| 3sw7 | 19K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.507 | |
| 4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.506 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.505 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.505 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.499 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.499 | |
| 3ti1 | B49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.499 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.499 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.498 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.497 | |
| 3qxp | X64 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.497 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.496 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.496 | |
| 2vtj | LZ4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.496 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.496 | |
| 1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.495 | |
| 3qzf | X66 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 3nup | 3NU | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.493 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.492 | |
| 1gii | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.489 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.489 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.489 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 2bhe | BRY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.487 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.487 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.487 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.487 | |
| 1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.486 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.486 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 4fks | 46K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.485 | |
| 4ogr | ADN | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.485 | |
| 3qtw | X3A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 1v0o | INR | Cell division control protein 2 homolog | 2.7.11.22 | 0.483 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 1gij | 2PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.481 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.481 | |
| 1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.480 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 1ke8 | LS4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.479 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 1pxp | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 4nj3 | 2KD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 1pye | PM1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 3o0g | 3O0 | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.476 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 2y7j | B49 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | 2.7.11.19 | 0.475 | |
| 3bhh | 5CP | Calcium/calmodulin-dependent protein kinase type II subunit beta | 2.7.11.17 | 0.475 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.473 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.473 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 3ezv | EZV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.472 | |
| 1w0x | OLO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 2ohv | NHL | Glutamate racemase | / | 0.471 | |
| 2vth | LZ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.471 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3fz1 | B98 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 4eol | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 3ql8 | X01 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.468 | |
| 4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.468 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.467 | |
| 2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 4aua | 4AU | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.467 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1xo2 | FSE | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.466 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.466 | |
| 3r6x | X84 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3roy | 22Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2vti | LZ3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2vtr | LZB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.464 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4eoo | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2r3p | 3SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.462 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3qtq | X35 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3qzg | X67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.461 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.461 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.461 | |
| 4lyn | 1YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 1pxk | CK3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.460 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.460 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3qqf | X07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 4bgq | 38R | Cyclin-dependent kinase-like 5 | 2.7.11.22 | 0.460 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2wsi | FAD | FAD synthase | 2.7.7.2 | 0.459 | |
| 3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.459 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.459 | |
| 1r78 | FMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.458 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.457 | |
| 3eld | SFG | Methyltransferase | / | 0.457 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.457 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4cfn | JYM | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2xmy | CDK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3ig7 | EFP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.456 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.455 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.455 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3s0o | 50Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1urw | I1P | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.454 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.453 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.453 | |
| 2r3k | SCQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.453 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 2w1h | L0F | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3blr | CPB | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.452 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.452 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.452 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1oiq | HDU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3qwk | X62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3r7u | X96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3rpy | 27Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.450 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.449 | |
| 2uzo | C62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.449 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.449 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.449 | |
| 3qx4 | X4B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.449 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.448 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.448 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 3r1q | X75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3r28 | XA0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3r73 | X87 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.448 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2r3l | SCW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.447 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3nux | 3NV | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.447 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3qzh | X69 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.447 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.446 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.446 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.446 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.446 | |
| 3mia | ANP | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.446 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.446 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.446 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.446 | |
| 1yvf | PH7 | Polyprotein | / | 0.445 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2qkr | IXM | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.445 | |
| 2uzn | C96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.445 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.445 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.445 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.444 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.444 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.444 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.444 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.444 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.443 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.443 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.443 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.443 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.443 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.442 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.442 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3r8p | Z46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4l44 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3qtx | X43 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3rus | ADP | Chaperonin | / | 0.441 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.441 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.441 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2qpy | DHT | Androgen receptor | / | 0.440 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3c4w | ATP | Rhodopsin kinase | / | 0.440 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.440 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 |