sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.787 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.783 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.776 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.767 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.722 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.567 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.539 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.536 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.534 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.519 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.509 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.507 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.502 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.501 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.499 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.492 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.491 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.489 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.487 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.485 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.485 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.484 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.483 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.482 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.481 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.481 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.478 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.478 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.477 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.476 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.475 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.475 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 4e32 | DWN | Methyltransferase | / | 0.473 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.473 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.472 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.472 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.470 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.469 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.469 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.469 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.467 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.466 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.466 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 4boe | CLR | Japanin | / | 0.466 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.466 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.465 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.465 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.463 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.463 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.463 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.463 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.462 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.462 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.462 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.462 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.461 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.461 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.460 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.460 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.459 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.459 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.459 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.459 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.459 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.458 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.458 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.458 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.457 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.457 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.457 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.456 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.456 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.456 | |
| 3eks | CY9 | Actin-5C | / | 0.456 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4iae | 1DX | Alr2278 protein | / | 0.456 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.456 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.456 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.455 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.455 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.455 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.455 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.454 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.454 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.454 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.454 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.454 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.454 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.454 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.453 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.453 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.453 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.453 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.453 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.452 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.452 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.452 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.452 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.452 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.452 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.452 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.452 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.451 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.451 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.451 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.451 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.451 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.451 | |
| 4pxl | NAD | Aldehyde dehydrogenase3 | / | 0.451 | |
| 1qjg | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.450 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.450 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.450 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.450 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.449 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.449 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3v2u | ATP | Protein GAL3 | / | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.448 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.448 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.447 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.447 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.446 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.446 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 1xa4 | COA | L-carnitine CoA-transferase | / | 0.445 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.445 | |
| 1ffy | MRC | Isoleucine--tRNA ligase | 6.1.1.5 | 0.444 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.444 | |
| 3nuv | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.444 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.444 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.444 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1l5r | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1swt | BTN | Streptavidin | / | 0.443 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.443 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.443 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.443 | |
| 1e2n | RCA | Thymidine kinase | / | 0.442 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1vce | SAH | Diphthine synthase | / | 0.442 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.442 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.442 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.441 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1s36 | CEI | Obelin | / | 0.441 | |
| 2izh | BTN | Streptavidin | / | 0.441 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.441 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.441 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4e2d | FMN | Dehydrogenase | / | 0.441 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.441 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.440 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2avi | BTN | Avidin | / | 0.440 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 2e20 | B4P | Propionate kinase | / | 0.440 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.440 | |
| 2po3 | T4K | 4-dehydrase | / | 0.440 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.440 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.440 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.440 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.440 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.440 |