sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 1.000 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.619 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.608 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.595 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.582 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.514 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.497 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.496 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.490 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.482 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.482 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.481 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.480 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.478 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.477 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.477 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.475 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.475 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 1rxj | BNI | Streptavidin | / | 0.474 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.474 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.473 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.473 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.472 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.471 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.470 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.469 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.469 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.469 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.468 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.467 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.465 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.465 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.465 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.464 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.463 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.463 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.463 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.462 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 2ejz | SAH | Diphthine synthase | / | 0.461 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.460 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.460 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 3p5s | AVU | CD38 molecule | / | 0.459 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.458 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.458 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 3kn0 | 3TO | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.458 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.458 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.457 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.457 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.457 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.457 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.457 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.456 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.456 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.456 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.456 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.456 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.456 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1vp5 | NAP | Oxidoreductase, aldo/keto reductase family | / | 0.455 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.455 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.455 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.455 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.455 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.455 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.454 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.454 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.454 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.453 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.453 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.453 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 2cbo | TH2 | Neocarzinostatin | / | 0.452 | |
| 2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.452 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 2e8w | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.451 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.451 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.450 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.450 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.450 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.449 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.449 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.449 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.449 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.449 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.449 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.448 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.448 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.448 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.448 | |
| 3c6n | 2S8 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.448 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.448 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.448 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.448 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.447 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.447 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.447 | |
| 4rel | KMP | Glycosyltransferase | / | 0.447 | |
| 4yfy | 1YJ | VioF | / | 0.447 | |
| 5doz | NDP | JamJ | / | 0.447 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.446 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 1w19 | T2P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.446 | |
| 2xeg | CI9 | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.446 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.446 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.445 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.445 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.445 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.445 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.445 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.445 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.444 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.444 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.444 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.444 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.444 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.444 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 1az2 | NAP | Aldose reductase | 1.1.1.21 | 0.443 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.443 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.443 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2yay | DUP | DUTPase | / | 0.443 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.443 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.443 | |
| 4cb6 | 29R | Polymerase basic protein 2 | / | 0.443 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.442 | |
| 1dp2 | LPB | Thiosulfate sulfurtransferase | / | 0.442 | |
| 1el4 | CTZ | Obelin | / | 0.442 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.442 | |
| 1swt | BTN | Streptavidin | / | 0.442 | |
| 1wm1 | PTB | Proline iminopeptidase | 3.4.11.5 | 0.442 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.442 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.442 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.442 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3ufy | NPX | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.442 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.441 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1qru | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.441 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.441 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.441 | |
| 3eks | CY9 | Actin-5C | / | 0.441 | |
| 3i9k | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | 3.2.2.6 | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4wxg | 2BO | Serine hydroxymethyltransferase | / | 0.441 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.440 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.440 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.440 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.440 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.440 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.440 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.440 | |
| 4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4j7g | TRH | PCZA361.3 | / | 0.440 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.440 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.440 | |
| 4yfy | 0FX | VioF | / | 0.440 | |
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 0.440 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.440 |