sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2euh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2euh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 1.000 | |
| 2qe0 | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.656 | |
| 2esd | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.622 | |
| 1qi1 | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.572 | |
| 4zvy | NAD | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.526 | |
| 4nmk | NAP | Aldehyde dehydrogenase | / | 0.510 | |
| 3b4w | NAD | Aldehyde dehydrogenase family protein | / | 0.509 | |
| 1bpw | NAD | Betaine aldehyde dehydrogenase | 1.2.1.8 | 0.498 | |
| 4l8u | 9AZ | Serum albumin | / | 0.495 | |
| 2xdr | NDP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.494 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.488 | |
| 1uxt | NAD | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.485 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.484 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.482 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.481 | |
| 3zqa | NDP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.479 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.477 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.477 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.476 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.476 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.473 | |
| 3rho | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.472 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.471 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.471 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.470 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.468 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.468 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.467 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.466 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.466 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.465 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.465 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.464 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.464 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1jut | LYD | Thymidylate synthase | / | 0.463 | |
| 2w8r | ADP | Succinate-semialdehyde dehydrogenase, mitochondrial | 1.2.1.24 | 0.463 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.461 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.461 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.461 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.460 | |
| 3gob | HXX | DdmC | / | 0.460 | |
| 3nt6 | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.460 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.459 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.459 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.458 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.458 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.457 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 2p15 | EZT | Estrogen receptor | / | 0.457 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.457 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.457 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.457 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.457 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.457 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1mei | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.456 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.456 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.456 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.456 | |
| 1i2l | DCS | Aminodeoxychorismate lyase | 4.1.3.38 | 0.455 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.455 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.455 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.455 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.455 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.455 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.455 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.454 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.453 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.453 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.453 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.452 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1qvr | ANP | Chaperone protein ClpB | / | 0.452 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.452 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 2xvq | 9DS | Serum albumin | / | 0.452 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.452 | |
| 3v9l | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.452 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.452 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.452 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.451 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.451 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4pb2 | 5UD | Nucleoside permease | / | 0.451 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.450 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.450 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.450 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.450 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 2j6l | NAI | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.450 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.450 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.450 | |
| 3zvv | XAZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4er7 | AW3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.450 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 4qos | ADP | Psp operon transcriptional activator | / | 0.450 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.450 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1s4e | ADP | Galactokinase | / | 0.449 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta | / | 0.449 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta' | / | 0.449 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.449 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.449 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.449 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.448 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.448 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.448 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4ihi | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.448 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 1sqv | UHD | Cytochrome b | / | 0.447 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.447 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.447 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.447 | |
| 3eem | 53V | Uncharacterized protein | / | 0.447 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.447 | |
| 3pqf | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 3r88 | 14F | Anthranilate phosphoribosyltransferase | / | 0.447 | |
| 4cs0 | ACO | PanD regulatory factor | / | 0.447 | |
| 5a3b | APR | SIR2 family protein | / | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.446 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.446 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.446 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.446 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3o15 | IFP | Thiamine-phosphate synthase | / | 0.446 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.446 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.446 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.446 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.446 | |
| 1bi9 | NAD | Retinal dehydrogenase 2 | / | 0.445 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.445 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.445 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1l4g | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.445 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.445 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.445 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.445 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3iw7 | IPK | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.445 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.445 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.445 | |
| 4i0r | 1B4 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.445 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.445 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.445 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.444 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.444 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 1y56 | FMN | Uncharacterized protein | / | 0.444 | |
| 1y56 | FMN | 382aa long hypothetical sarcosine oxidase | / | 0.444 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.444 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.444 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.444 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.443 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.443 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.443 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.443 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.443 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.443 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.443 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.443 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 5a3c | NAD | SIR2 family protein | / | 0.443 | |
| 1g69 | TZP | Thiamine-phosphate synthase | / | 0.442 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.442 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.442 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.442 | |
| 2imp | NAI | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.442 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2vht | ATP | NTPase P4 | / | 0.442 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.442 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3w2n | ROD | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.442 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.442 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.442 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.442 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.442 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.442 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.441 | |
| 1f0y | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2czf | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.441 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.441 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.441 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.441 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3pvr | BYC | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.441 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.441 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.441 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 4hys | 1BJ | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.441 | |
| 5cyo | GDP | Septin-9 | / | 0.441 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.440 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.440 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.440 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.440 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.440 | |
| 2xvw | 9NR | Serum albumin | / | 0.440 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 3eai | 328 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.440 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.440 | |
| 3zsi | 52P | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 |