sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1w6y | EQU | Steroid Delta-isomerase | 5.3.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1w6y | EQU | Steroid Delta-isomerase | 5.3.3.1 | 1.000 | |
| 1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.644 | |
| 1oh0 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.629 | |
| 3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.591 | |
| 1gs3 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.587 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.572 | |
| 3nhx | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.572 | |
| 3owy | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.571 | |
| 1ogx | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.569 | |
| 1e3r | AND | Steroid Delta-isomerase | 5.3.3.1 | 0.568 | |
| 1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.562 | |
| 3vgn | FNN | Steroid Delta-isomerase | 5.3.3.1 | 0.531 | |
| 1oho | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.511 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.510 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.502 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.493 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.490 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.490 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.486 | |
| 3owu | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.486 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.485 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.485 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.484 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.484 | |
| 1y5v | NE8 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.483 | |
| 4oic | A8S | Bet v I allergen-like | / | 0.482 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.480 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.477 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.477 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.476 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.476 | |
| 3kb3 | A8S | Abscisic acid receptor PYL2 | / | 0.475 | |
| 4ug5 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.475 | |
| 2j5s | KTA | Alr4455 protein | / | 0.474 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.474 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3ov4 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.473 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.473 | |
| 2kb2 | FMN | Uncharacterized protein | / | 0.472 | |
| 2j62 | GSZ | O-GlcNAcase NagJ | / | 0.471 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.471 | |
| 3h03 | UBP | Glutamate receptor 2 | / | 0.469 | |
| 3m8c | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.469 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.469 | |
| 1bp0 | UMP | Thymidylate synthase | / | 0.468 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.468 | |
| 2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.468 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.468 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 3ert | OHT | Estrogen receptor | / | 0.467 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.466 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.466 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.466 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.466 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.465 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.463 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.463 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.463 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.463 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.463 | |
| 4ug5 | XFK | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.463 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1tdc | UMP | Thymidylate synthase | / | 0.462 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3rga | LSB | Epoxide hydrolase LasB | 5.5.1 | 0.462 | |
| 4an2 | EUI | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.462 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3flq | 891 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.461 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.460 | |
| 3kdj | A8S | Abscisic acid receptor PYL1 | / | 0.460 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 1njb | UMP | Thymidylate synthase | / | 0.459 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.459 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.459 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.459 | |
| 1coy | AND | Cholesterol oxidase | 1.1.3.6 | 0.458 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2xiz | XIZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.458 | |
| 3nmv | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.457 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.457 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.457 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.457 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.457 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.456 | |
| 2hiw | 7MP | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.456 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.456 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.456 | |
| 2ido | TMP | DNA polymerase III subunit epsilon | 2.7.7.7 | 0.455 | |
| 3vew | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.455 | |
| 4hw7 | 64M | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.455 | |
| 4mmc | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.455 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.454 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.454 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.454 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.454 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.454 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.454 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 4at2 | ASD | Possible succinate dehydrogenase | / | 0.454 | |
| 4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4pda | CTN | Nucleoside permease | / | 0.454 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.453 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.453 | |
| 2pmn | K51 | Protein kinase 7 | / | 0.453 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 4dma | 0L8 | Estrogen receptor | / | 0.453 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.453 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.453 | |
| 4wxg | 2BO | Serine hydroxymethyltransferase | / | 0.453 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.452 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.452 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.452 | |
| 1qiw | DPD | Calmodulin | / | 0.452 | |
| 1qvt | PRL | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2hxd | DUP | dCTP deaminase, dUMP-forming | 3.5.4.30 | 0.452 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3up3 | XCA | aceDAF-12 | / | 0.452 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4zvm | DM2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.452 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.451 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.451 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.451 | |
| 4l8u | 9AZ | Serum albumin | / | 0.451 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.451 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.450 | |
| 1zdf | UPG | Glycogenin-1 | 2.4.1.186 | 0.450 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.450 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.450 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.450 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.450 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.450 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 2btd | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.449 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 2qxx | TTP | dCTP deaminase | 3.5.4.13 | 0.449 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.449 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.449 | |
| 4bbg | V02 | Kinesin-like protein KIF11 | / | 0.449 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.449 | |
| 1im2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.448 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.448 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.448 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.448 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.448 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3zrb | ORC | Progesterone receptor | / | 0.448 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.448 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.448 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.447 | |
| 2acw | UPG | Glycosyltransferase | / | 0.447 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 3h18 | PMS | Esterase/lipase | / | 0.447 | |
| 3kt8 | LTN | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.447 | |
| 3nnx | EDD | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 4fvz | 4KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 4jsh | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.447 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4pb1 | RBV | Nucleoside permease | / | 0.447 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.447 | |
| 1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1fkx | PRH | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1j3j | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1qjg | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
| 1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.446 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2agv | BHQ | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.446 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.446 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3k14 | 535 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.446 | |
| 3k2x | I5A | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.446 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.446 | |
| 4cf2 | 3GM | Integrase | / | 0.446 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.446 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.446 | |
| 1mjt | NAD | Nitric oxide synthase oxygenase | / | 0.445 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.445 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3dga | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.445 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.445 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.445 | |
| 4jv3 | N32 | Beta-ketoacyl synthase | / | 0.445 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.445 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.445 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.445 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.445 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.444 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.444 | |
| 1yy4 | 4NA | Estrogen receptor beta | / | 0.444 | |
| 2oyf | IAC | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.444 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.444 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.444 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.444 | |
| 3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.444 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.444 | |
| 3qw2 | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.444 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.444 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.443 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.443 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.443 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.443 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.443 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.443 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.443 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4fv8 | E63 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4isk | UMP | Thymidylate synthase | / | 0.443 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 1m8i | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.442 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.442 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2fai | 459 | Estrogen receptor | / | 0.442 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.442 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.442 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.442 | |
| 3vf2 | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.442 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.442 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.442 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2xiy | XIY | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.441 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4a9s | RU9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4an3 | 5Y0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.441 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.441 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 4o4e | ATP | Kinase | / | 0.441 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.440 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1h48 | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.440 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.440 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.440 | |
| 1qbs | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2pot | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.440 | |
| 3eah | 327 | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.440 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.440 | |
| 3i64 | DNA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.440 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3q5i | ANP | Protein kinase, putative | / | 0.440 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3tlj | SAH | Uncharacterized protein | / | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4js9 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.440 |