Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1o69 | X04 | Aminotransferase DegT |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1o69 | X04 | Aminotransferase DegT | / | 1.000 | |
4die | C5P | Cytidylate kinase | / | 0.494 | |
2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.491 | |
4q0k | GA3 | Phytohormone-binding protein | / | 0.483 | |
3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.482 | |
3tjz | GNP | ADP-ribosylation factor 1 | / | 0.480 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.480 | |
1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.479 | |
2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.479 | |
3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.479 | |
4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.477 | |
4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.477 | |
3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.476 | |
1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.474 | |
3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.474 | |
1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.473 | |
1e2n | RCA | Thymidine kinase | / | 0.472 | |
1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.472 | |
2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.472 | |
2hfu | MEV | Mevalonate kinase | / | 0.471 | |
2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.471 | |
2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.471 | |
4e2d | FMN | Dehydrogenase | / | 0.471 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.471 | |
2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.470 | |
2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.470 | |
3h06 | VBP | Glutamate receptor 2 | / | 0.470 | |
3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.470 | |
1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.469 | |
1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.469 | |
1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.469 | |
2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.469 | |
2gr0 | ADP | Ferredoxin reductase | / | 0.469 | |
4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.469 | |
2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.468 | |
2xtn | GTP | GTPase IMAP family member 2 | / | 0.468 | |
1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.467 | |
1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.467 | |
3pka | Y02 | Methionine aminopeptidase 2 | / | 0.467 | |
4l4x | NDP | AmphI | / | 0.467 | |
1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.466 | |
2ahc | VNL | Chorismate pyruvate-lyase | / | 0.466 | |
4f9g | C2E | Stimulator of interferon genes protein | / | 0.466 | |
4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.466 | |
1txt | CAA | HMG-CoA synthase | / | 0.465 | |
1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.465 | |
3bgx | MEF | Thymidylate synthase | / | 0.465 | |
3h2s | NDP | Putative NADH-flavin reductase | / | 0.465 | |
4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.465 | |
1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.464 | |
5kwv | ANP | Pantothenate synthetase | / | 0.464 | |
1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.463 | |
5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.463 | |
1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.462 | |
2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.462 | |
2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.462 | |
2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.462 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.462 | |
4lcj | NAD | C-terminal-binding protein 2 | / | 0.462 | |
1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.461 | |
1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.461 | |
2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.461 | |
2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
2zre | AGS | Protein RecA | / | 0.461 | |
4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.461 | |
5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.461 | |
5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.461 | |
1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.460 | |
1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.460 | |
1xdd | AAY | Integrin alpha-L | / | 0.460 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.460 | |
2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.460 | |
3gqv | NAP | Enoyl reductase LovC | 1 | 0.460 | |
3k4y | IPE | Isopentenyl phosphate kinase | 2.7.4.26 | 0.460 | |
4biw | ANP | Sensor histidine kinase CpxA | / | 0.460 | |
5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.460 | |
1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.459 | |
1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.459 | |
2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.459 | |
2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.459 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
2yvg | NAD | Ferredoxin reductase | / | 0.459 | |
3uqd | ADP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.459 | |
4pzs | ACO | Histone acetyltransferase p300 | / | 0.459 | |
5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.459 | |
1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.458 | |
1lbc | CYZ | Glutamate receptor 2 | / | 0.458 | |
2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.458 | |
3e8x | NAP | BH1520 protein | / | 0.458 | |
3gvh | NAD | Malate dehydrogenase | / | 0.458 | |
3tr0 | 5GP | Guanylate kinase | / | 0.458 | |
4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.458 | |
1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.457 | |
2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.457 | |
3aty | FMN | Prostaglandin F2a synthase | / | 0.457 | |
3bbr | BHY | Glutamate receptor 2 | / | 0.457 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.457 | |
1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.456 | |
2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
3dme | FAD | Putative conserved exported protein | / | 0.456 | |
3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
3p19 | NDP | Putative blue fluorescent protein | / | 0.456 | |
4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.456 | |
5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.456 | |
1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.455 | |
2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.455 | |
2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.455 | |
2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.455 | |
2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
3b70 | NAP | Enoyl reductase LovC | 1 | 0.455 | |
3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.455 | |
3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.455 | |
3up0 | D7S | aceDAF-12 | / | 0.455 | |
4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.455 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.454 | |
1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.454 | |
1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.454 | |
2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.454 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
3koq | FMN | Putative nitroreductase | / | 0.454 | |
3pcr | GTP | ADP-ribosylation factor 6 | / | 0.454 | |
3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.454 | |
4ef4 | C2E | Stimulator of interferon genes protein | / | 0.454 | |
4hxy | NDP | Plm1 | / | 0.454 | |
4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.454 | |
4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.454 | |
4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.454 | |
4y9q | C2E | Uncharacterized protein | / | 0.454 | |
5dp2 | NAP | CurF | / | 0.454 | |
1uxj | NAD | Malate dehydrogenase | / | 0.453 | |
2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.453 | |
2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.453 | |
2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.453 | |
2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.453 | |
2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.453 | |
2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.453 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.453 | |
3wag | TYD | Glycosyltransferase | / | 0.453 | |
4ba5 | PXG | Probable aminotransferase | / | 0.453 | |
4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.453 | |
4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.453 | |
4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.453 | |
4wec | NAD | Short chain dehydrogenase | / | 0.453 | |
1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.452 | |
1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
2g1n | 1IG | Renin | 3.4.23.15 | 0.452 | |
3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.452 | |
3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.452 | |
3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
3hyo | ADP | Pyridoxal kinase | / | 0.452 | |
3i0p | NAD | Malate dehydrogenase, putative | / | 0.452 | |
4dae | 6CR | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.452 | |
4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.452 | |
4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.452 | |
4qxp | 1YE | Stimulator of interferon genes protein | / | 0.452 | |
4yag | NAI | C alpha-dehydrogenase | / | 0.452 | |
4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.452 | |
1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
2gvd | FKP | Adenylate cyclase type 2 | / | 0.451 | |
2gvd | FKP | Adenylate cyclase type 5 | / | 0.451 | |
2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
3cwq | ADP | ParA family chromosome partitioning protein | / | 0.451 | |
3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.451 | |
4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.451 | |
4loi | 1YC | Stimulator of interferon genes protein | / | 0.451 | |
4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.451 | |
1uxk | NAD | Malate dehydrogenase | / | 0.450 | |
2ffq | GSP | Ras-related protein Rab-6B | / | 0.450 | |
2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.450 | |
3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.450 | |
3opx | U5P | Suppressor of disruption of TFIIS | / | 0.450 | |
4img | NGF | N-acetylneuraminate lyase | / | 0.450 | |
4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.450 | |
5eso | ISC | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.450 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.449 | |
1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.449 | |
1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
1xjq | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.449 | |
2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.449 | |
2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.449 | |
3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.449 | |
3kb6 | NAD | D-lactate dehydrogenase | / | 0.449 | |
3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.449 | |
3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.449 | |
3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.449 | |
1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.448 | |
1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.448 | |
1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.448 | |
2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.448 | |
2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.448 | |
3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.448 | |
3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
4de3 | DN8 | Beta-lactamase | / | 0.448 | |
4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.448 | |
4fhd | 0TT | Spore photoproduct lyase | / | 0.448 | |
4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
5c3a | URM | Histo-blood group ABO system transferase | / | 0.448 | |
1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.447 | |
1ib6 | NAD | Malate dehydrogenase | / | 0.447 | |
1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.447 | |
2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
3h86 | AP5 | Adenylate kinase | / | 0.447 | |
3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.447 | |
3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.447 | |
3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.447 | |
3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.447 | |
4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.447 | |
5a9s | NAP | Putative dehydrogenase | / | 0.447 | |
1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.446 | |
2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.446 | |
2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.446 | |
2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
2q3f | GNP | Ras-related GTP-binding protein D | / | 0.446 | |
2rhg | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.446 | |
3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.446 | |
3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.446 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.446 | |
4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
4dna | FAD | Probable glutathione reductase | / | 0.446 | |
4e03 | ADP | Plasmid partitioning protein ParF | / | 0.446 | |
4gdd | NAI | UDP-galactopyranose mutase | / | 0.446 | |
4h0v | NAD | Iota toxin component Ia | / | 0.446 | |
4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
4nvk | 2NY | Peroxidase | / | 0.446 | |
4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.446 | |
1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.445 | |
1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.445 | |
1kh3 | ANP | Argininosuccinate synthase | / | 0.445 | |
1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
1nj6 | A5A | Proline--tRNA ligase | / | 0.445 | |
1xts | GTP | GTP-binding protein Rheb | / | 0.445 | |
2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.445 | |
2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.445 | |
3cb2 | GDP | Tubulin gamma-1 chain | / | 0.445 | |
3e39 | FMN | Nitroreductase | / | 0.445 | |
3l06 | SN0 | N-acetylornithine carbamoyltransferase | 2.1.3.9 | 0.445 | |
3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.445 | |
4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
4rgs | V55 | Repressor protein | / | 0.445 | |
1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.444 | |
1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.444 | |
1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
2ejz | SAH | Diphthine synthase | / | 0.444 | |
2gz7 | D3F | Orf1a polyprotein | / | 0.444 | |
2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
2j2p | SC2 | Ficolin-2 | / | 0.444 | |
2ome | NAD | C-terminal-binding protein 2 | / | 0.444 | |
2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
2zr9 | DTP | Protein RecA | / | 0.444 | |
2zro | ADP | Protein RecA | / | 0.444 | |
3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.444 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.444 | |
4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.444 | |
4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.444 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.444 | |
4py2 | 43E | Methionine--tRNA ligase | / | 0.444 | |
4qxq | 1YE | Stimulator of interferon genes protein | / | 0.444 | |
5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.444 | |
3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.444 | |
1fxs | NAP | GDP-L-fucose synthase | / | 0.443 | |
1guy | NAD | Malate dehydrogenase | / | 0.443 | |
1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
1svl | ADP | Large T antigen | 3.6.4 | 0.443 | |
2a7r | 5GP | GMP reductase 2 | / | 0.443 | |
2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.443 | |
2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.443 | |
3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.443 | |
4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.443 | |
4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.443 | |
5a3b | APR | SIR2 family protein | / | 0.443 | |
1a5b | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.442 | |
1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.442 | |
2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.442 | |
2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.442 | |
3cgc | COA | Coenzyme A disulfide reductase | / | 0.442 | |
3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.442 | |
3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.442 | |
3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.442 | |
4du6 | GTP | GTP cyclohydrolase 1 | / | 0.442 | |
4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.442 | |
5cyo | GDP | Septin-9 | / | 0.442 | |
5fsy | AR6 | Uncharacterized protein | / | 0.442 | |
5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
5jjs | SAH | Genome polyprotein | / | 0.442 | |
8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.441 | |
1mja | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
1nzd | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.441 | |
2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.441 | |
2c20 | NAD | UDP-glucose 4-epimerase | / | 0.441 | |
2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.441 | |
2ozr | GG1 | Collagenase 3 | 3.4.24 | 0.441 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
2zyn | BCD | Periplasmic binding protein | / | 0.441 | |
3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.441 | |
3hlw | CE3 | Beta-lactamase | / | 0.441 | |
3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.441 | |
3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.441 | |
3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
3ziu | LSS | Leucyl-tRNA synthetase | / | 0.441 | |
4de2 | DN3 | Beta-lactamase | / | 0.441 | |
4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.441 | |
4wbn | GTP | Tubulin alpha-1B chain | / | 0.441 | |
4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.441 | |
1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 | |
1zdf | UPG | Glycogenin-1 | 2.4.1.186 | 0.440 | |
2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
2nv4 | SAM | S-adenosyl-L-methionine-binding protein AF_0241 | / | 0.440 | |
2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
2x8g | FAD | Thioredoxin glutathione reductase | / | 0.440 | |
2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
3c15 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
3c15 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
3hf3 | FMN | Chromate reductase | / | 0.440 | |
3pft | FMN | Flavin reductase | / | 0.440 | |
3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.440 | |
3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.440 | |
4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.440 | |
4emt | C2E | Stimulator of interferon genes protein | / | 0.440 | |
4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.440 |