sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ule | C69 | Actin-related protein 3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ule | C69 | Actin-related protein 3 | / | 1.000 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.691 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.627 | |
| 4lb2 | DM5 | Serum albumin | / | 0.500 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.488 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.480 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.477 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.477 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.475 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.474 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.473 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.472 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.472 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.468 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.467 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.466 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.466 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.465 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.465 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.464 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.464 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.464 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.463 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.462 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.461 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.461 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.461 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.461 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.461 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.461 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.461 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.461 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.461 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.460 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.460 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.460 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.460 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.460 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.460 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.459 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.459 | |
| 3b89 | 5GP | 16S rRNA methylase | / | 0.459 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.459 | |
| 3zuy | TCH | Transporter | / | 0.459 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.459 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.459 | |
| 5a3b | APR | SIR2 family protein | / | 0.459 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.458 | |
| 1osv | CHC | Bile acid receptor | / | 0.458 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.458 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.458 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.457 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.457 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.457 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.457 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.456 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.456 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.456 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.455 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.455 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.455 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.455 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.455 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.455 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.454 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.454 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.454 | |
| 4yqf | GDP | Septin-9 | / | 0.454 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.453 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.453 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.453 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.453 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.453 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.453 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.452 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.452 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.452 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.451 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.451 | |
| 2bxo | OPB | Serum albumin | / | 0.451 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.451 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.451 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3h8b | NSY | Cathepsin L1 | 3.4.22.15 | 0.451 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.450 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.450 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.450 | |
| 2ejz | SAH | Diphthine synthase | / | 0.450 | |
| 2i0d | MUT | Protease | / | 0.450 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.450 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.450 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.450 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.450 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.450 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.450 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.450 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 5a3c | NAD | SIR2 family protein | / | 0.450 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.449 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.449 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.449 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.449 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 3ieu | GDP | GTPase Era | / | 0.449 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.449 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1c70 | L75 | Protease | / | 0.448 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.448 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.448 | |
| 3lu8 | IQX | Serum albumin | / | 0.448 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.448 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.447 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.447 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.447 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.446 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.446 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.446 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.446 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.446 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.446 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.446 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.446 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4b1f | KRH | Glutamate racemase | / | 0.446 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.446 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.446 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.446 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.445 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.445 | |
| 1me7 | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.445 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.445 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.445 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.444 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.444 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.444 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.444 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.444 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.444 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.444 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.444 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.444 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.444 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.444 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.444 | |
| 5cno | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.444 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.443 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.443 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.443 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.443 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.443 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.443 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.443 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.443 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.443 | |
| 1a2n | TET | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.442 | |
| 1jld | 0PP | Gag-Pol polyprotein | / | 0.442 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.442 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.442 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.442 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.442 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.442 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.442 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.442 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.442 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.442 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.442 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.442 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.442 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.442 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1o1v | TCH | Gastrotropin | / | 0.441 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 2y3s | TIR | TamL | / | 0.441 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.441 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.441 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.441 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4n6b | COA | Uncharacterized protein | / | 0.441 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.441 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.440 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.440 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.440 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.440 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.440 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.440 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.440 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.440 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.440 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.440 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.440 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.440 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.440 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.440 |