sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3jwm | 5WB | Dihydrofolate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3jwm | 5WB | Dihydrofolate reductase | / | 1.000 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.616 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.606 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.598 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.596 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.596 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.596 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.581 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.581 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.581 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.580 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.578 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.574 | |
| 3cse | N22 | Uncharacterized protein | / | 0.570 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.569 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.569 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.569 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.568 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.563 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.562 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.555 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.550 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
| 3eel | 53T | Uncharacterized protein | / | 0.548 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
| 3eej | 53R | Uncharacterized protein | / | 0.547 | |
| 3eek | 53S | Uncharacterized protein | / | 0.545 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.539 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.537 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.536 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.535 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.533 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.531 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 3qly | 55V | Uncharacterized protein | / | 0.529 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.525 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.525 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.524 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.519 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 4l9q | 9TP | Serum albumin | / | 0.512 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
| 3eem | 53V | Uncharacterized protein | / | 0.511 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.510 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.510 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.510 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.509 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.508 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.508 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.506 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.505 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.503 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.502 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.501 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.501 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.501 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.499 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.498 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.497 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.496 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.494 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.493 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.493 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.491 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.491 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.491 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.490 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.489 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.488 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.487 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.487 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.486 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.486 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.486 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.485 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.485 | |
| 3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.484 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.484 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.484 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.483 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.483 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.482 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.482 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.482 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.482 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.481 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.481 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.480 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.480 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.479 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.478 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.478 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.478 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.478 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.478 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.478 | |
| 4v12 | POG | MaoC like domain protein | / | 0.478 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.477 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3lu8 | IQX | Serum albumin | / | 0.477 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.477 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.477 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.476 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 2jfa | RAL | Estrogen receptor | / | 0.475 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3zuy | TCH | Transporter | / | 0.475 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.475 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.475 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.474 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.474 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.474 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.474 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.473 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.473 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.473 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.472 | |
| 1fml | RTL | Retinol dehydratase | / | 0.471 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.471 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.471 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.471 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.470 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.470 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.470 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1ysx | 4EB | Serum albumin | / | 0.469 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.469 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.468 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.468 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.467 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.467 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.467 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.467 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.467 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.466 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 1pp9 | SMA | Cytochrome b | / | 0.466 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.466 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.466 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.466 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.466 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.466 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.466 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.466 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.466 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.466 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.465 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.465 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.465 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.465 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.464 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.464 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.464 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.464 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.464 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.463 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.463 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.463 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.463 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.463 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.462 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.462 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2ybo | SAH | Methyltransferase | / | 0.461 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.461 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.461 | |
| 3p9t | TCL | Repressor | / | 0.461 | |
| 3q30 | D61 | Squalene synthase | 2.5.1.21 | 0.461 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.461 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.461 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.460 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.460 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 3dol | GWI | Pol protein | / | 0.460 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.460 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.460 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.460 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 4k9v | 6AW | Cytochrome P450 3A4 | / | 0.460 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.459 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.459 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.459 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3lu7 | IPX | Serum albumin | / | 0.459 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.459 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.459 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4f9w | LM4 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.459 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.459 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.458 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.458 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.458 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.458 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.458 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.458 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.458 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.458 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4l8u | 9AZ | Serum albumin | / | 0.458 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.458 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.458 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.457 | |
| 1ie4 | T44 | Transthyretin | / | 0.457 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.457 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.457 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.457 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.457 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.457 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.457 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.457 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.457 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.457 | |
| 4inb | 1F6 | Gag protein | / | 0.457 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.456 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.456 | |
| 1osv | CHC | Bile acid receptor | / | 0.456 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.456 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.456 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.456 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.456 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.456 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.456 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.456 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.455 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.455 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.455 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.455 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.455 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.455 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.455 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.455 | |
| 3zux | TCH | Transporter | / | 0.455 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.455 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.455 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.454 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.454 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.454 | |
| 3nxu | RIT | Cytochrome P450 3A4 | / | 0.454 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.454 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.454 | |
| 4z9r | NAD | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.454 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.453 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.453 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.453 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.453 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.453 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.453 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.453 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.452 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.452 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.452 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.452 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3rpn | GTX | Glutathione S-transferase kappa 1 | 2.5.1.18 | 0.452 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.452 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.452 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4l9k | EHF | Serum albumin | / | 0.452 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.451 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.451 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.451 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.451 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.451 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.451 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.451 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.451 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.451 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.451 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.451 | |
| 3tgu | WF3 | Cytochrome b | / | 0.451 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.451 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.451 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 1p7t | ACO | Malate synthase G | / | 0.450 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2p15 | EZT | Estrogen receptor | / | 0.450 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.450 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.450 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.450 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.450 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.450 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.450 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.449 | |
| 3h1j | SMA | Cytochrome b | / | 0.449 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.449 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.449 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.449 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.449 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.449 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.448 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.448 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.448 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.448 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.448 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.448 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.448 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.448 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.448 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.448 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.448 | |
| 4lb2 | DM5 | Serum albumin | / | 0.448 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 1ict | T44 | Transthyretin | / | 0.447 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.447 | |
| 2dwp | ACP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.447 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.447 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.447 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.447 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.447 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3p3e | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.447 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.447 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.447 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.447 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.447 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.447 | |
| 4ok1 | 198 | Androgen receptor | / | 0.447 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.446 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1w84 | L12 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.446 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.446 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.446 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.446 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.446 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.446 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.446 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.446 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.446 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.446 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.446 | |
| 1e7a | PFL | Serum albumin | / | 0.445 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.445 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.445 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.445 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.445 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.445 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.445 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.445 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.445 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.445 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 4egn | TWO | Cytochrome P450 | / | 0.445 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 4ivw | 1GJ | Estrogen receptor | / | 0.445 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.445 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1hk3 | T44 | Serum albumin | / | 0.444 | |
| 1khr | COA | Streptogramin A acetyltransferase | 2.3.1 | 0.444 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.444 | |
| 1syn | F89 | Thymidylate synthase | / | 0.444 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.444 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.444 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.444 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.444 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 3zsi | 52P | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.444 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.444 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.444 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.444 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.443 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.443 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.443 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.443 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.443 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.443 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.443 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 4mxy | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 4mxz | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.442 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 2jfz | 003 | Glutamate racemase | / | 0.442 | |
| 2pir | DHT | Androgen receptor | / | 0.442 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.442 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.442 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.442 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 3wd7 | COA | Acridone synthase | / | 0.442 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.442 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.442 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.442 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.442 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.442 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.442 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.442 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.441 | |
| 2ghm | LIC | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.441 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.441 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.441 | |
| 2y3s | TIR | TamL | / | 0.441 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.441 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.441 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.441 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.441 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.440 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.440 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1sqv | UHD | Cytochrome b | / | 0.440 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.440 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.440 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.440 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.440 | |
| 3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3t80 | CTN | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.440 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.440 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4o28 | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.440 |