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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2o65MYFSerine/threonine-protein kinase pim-12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2o65MYFSerine/threonine-protein kinase pim-12.7.11.11.000
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.606
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.604
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.594
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.588
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.588
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.588
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.578
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.576
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.573
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.572
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.567
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.565
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.561
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.557
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.554
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.554
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.554
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.550
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.550
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.550
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.549
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.546
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.546
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.546
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.544
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.541
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.540
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.539
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.535
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.535
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.534
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.530
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.530
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.530
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.528
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.527
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.524
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.522
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.521
2xa4AZ5Tyrosine-protein kinase JAK2/0.520
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.518
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.516
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.514
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.511
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.510
2xikJ60Serine/threonine-protein kinase 252.7.11.10.509
3oom507Activin receptor type-12.7.11.300.509
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.505
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.504
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.503
4jia1K3Tyrosine-protein kinase JAK2/0.501
5cvhADPCasein kinase II subunit alpha2.7.11.10.499
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.496
4gmy0X5Tyrosine-protein kinase JAK2/0.494
1xjdSTUProtein kinase C theta type2.7.11.130.492
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.492
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.491
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.491
3a4pDFQHepatocyte growth factor receptor2.7.10.10.490
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.490
3nga3NGCasein kinase II subunit alpha2.7.11.10.489
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.487
3iw4LW4Protein kinase C alpha type2.7.11.130.487
4fob0USALK tyrosine kinase receptor2.7.10.10.487
4hvi19STyrosine-protein kinase JAK32.7.10.20.485
2wihP48Cyclin-dependent kinase 22.7.11.220.484
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.484
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.483
4gg70J8Hepatocyte growth factor receptor2.7.10.10.483
2pvlP55Casein kinase II subunit alpha2.7.11.10.482
3be9P04Casein kinase II subunit alpha2.7.11.10.482
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.482
4i22IREEpidermal growth factor receptor2.7.10.10.481
5auwQUEDeath-associated protein kinase 12.7.11.10.481
1gqtACPRibokinase/0.480
2h96893Mitogen-activated protein kinase 82.7.11.240.480
2x7gPVBSRSF protein kinase 22.7.11.10.480
2p33J07Mitogen-activated protein kinase 102.7.11.240.479
4dymIYZActivin receptor type-12.7.11.300.479
1aq1STUCyclin-dependent kinase 22.7.11.220.478
1e9hINRCyclin-dependent kinase 22.7.11.220.478
2pvnP63Casein kinase II subunit alpha2.7.11.10.478
3bu5ATPInsulin receptor2.7.10.10.478
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.478
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.478
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.478
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.477
3bqr4RBDeath-associated protein kinase 3/0.477
3du8553Glycogen synthase kinase-3 beta2.7.11.260.477
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.477
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.477
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.477
4dgnLU2Casein kinase II subunit alpha2.7.11.10.477
5auxKMPDeath-associated protein kinase 12.7.11.10.476
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.475
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.475
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.475
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.475
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.474
2j0lANPFocal adhesion kinase 12.7.10.20.474
4grb0XGCasein kinase II subunit alpha2.7.11.10.474
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.474
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.473
4gg50J3Hepatocyte growth factor receptor2.7.10.10.473
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.473
4jqeANPCasein kinase II subunit alpha2.7.11.10.473
4lopSB4Mitogen-activated protein kinase 14/0.473
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.472
3gubGUBDeath-associated protein kinase 12.7.11.10.472
3umw596Serine/threonine-protein kinase pim-12.7.11.10.472
4jq8KJ8Epidermal growth factor receptor2.7.10.10.472
1wvxBD4Death-associated protein kinase 12.7.11.10.471
2hog710Serine/threonine-protein kinase Chk12.7.11.10.471
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.471
3q9xEMOCasein kinase II subunit alpha2.7.11.10.471
4mwhATPCasein kinase II subunit alpha2.7.11.10.471
1oiyN41Cyclin-dependent kinase 22.7.11.220.470
1pmn984Mitogen-activated protein kinase 102.7.11.240.470
2x1nX1NCyclin-dependent kinase 22.7.11.220.470
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.470
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.469
3vt7VDXVitamin D3 receptor/0.469
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.469
4j95ACPFibroblast growth factor receptor 2/0.469
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.468
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.468
4e4m0NHTyrosine-protein kinase JAK2/0.468
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.468
2izsBRQCasein kinase I isoform gamma-32.7.11.10.467
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.467
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.467
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.467
4lfiGNPCasein kinase II subunit alpha2.7.11.10.467
4othDRNSerine/threonine-protein kinase N1/0.467
5e8wSTUTGF-beta receptor type-12.7.11.300.467
1di8DTQCyclin-dependent kinase 22.7.11.220.466
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.466
3nszANPCasein kinase II subunit alpha2.7.11.10.466
3q9zTXQCasein kinase II subunit alpha2.7.11.10.466
4bgg844Activin receptor type-12.7.11.300.466
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4jr7GNPCasein kinase II subunit alpha2.7.11.10.466
4yuqKS1Calmodulin-like domain protein kinase/0.466
1om1IQACasein kinase II subunit alpha2.7.11.10.465
1u54ACPActivated CDC42 kinase 1/0.465
2avvMK1Gag-Pol polyprotein3.4.23.160.465
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.465
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.465
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.465
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.464
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.464
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.464
4gub0Y4Casein kinase II subunit alpha2.7.11.10.464
1n4hREANuclear receptor ROR-beta/0.463
2cchATPCyclin-dependent kinase 22.7.11.220.463
2etm7PYFocal adhesion kinase 12.7.10.20.463
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.463
1yvj4STTyrosine-protein kinase JAK32.7.10.20.462
2itpAEEEpidermal growth factor receptor2.7.10.10.462
2py3ACPFibroblast growth factor receptor 2/0.462
3dds26BGlycogen phosphorylase, liver form2.4.1.10.462
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.462
3hl7I47Mitogen-activated protein kinase 14/0.462
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.462
4g1wG1WMitogen-activated protein kinase 82.7.11.240.462
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
3gc9B45Mitogen-activated protein kinase 112.7.11.240.461
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.461
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.461
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4fnyI3KALK tyrosine kinase receptor2.7.10.10.461
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.461
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.461
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.461
4hvh19RTyrosine-protein kinase JAK32.7.10.20.461
4qmzB49Serine/threonine-protein kinase 242.7.11.10.461
4wboANWRhodopsin kinase/0.461
1bygSTUTyrosine-protein kinase CSK/0.460
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.460
3akn11DFatty acid-binding protein, intestinal/0.460
3t8oATPRhodopsin kinase/0.460
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.460
4hnf16WCasein kinase I isoform delta2.7.11.10.460
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.460
4riyADPEpidermal growth factor receptor2.7.10.10.460
1lp4ANPCasein kinase II subunit alpha2.7.11.10.459
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.459
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2excJNKMitogen-activated protein kinase 102.7.11.240.459
2itqITQEpidermal growth factor receptor2.7.10.10.459
2pmoHMDProtein kinase 7/0.459
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.459
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.459
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
4gk2L66Ephrin type-A receptor 32.7.10.10.459
4gk4L90Ephrin type-A receptor 32.7.10.10.459
1ppm0P1Penicillopepsin-13.4.23.200.458
1rfuADPPyridoxal kinase2.7.1.350.458
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
2uxpCLMHTH-type transcriptional regulator TtgR/0.458
2wedPP6Penicillopepsin-13.4.23.200.458
2zbaZBATrichothecene 3-O-acetyltransferase/0.458
3gbuATPUncharacterized sugar kinase PH14592.7.10.458
3vt9YI4Vitamin D3 receptor/0.458
4a84DXCMajor pollen allergen Bet v 1-A/0.458
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
1zys199Serine/threonine-protein kinase Chk12.7.11.10.457
2izrBRKCasein kinase I isoform gamma-32.7.11.10.457
3a60STURibosomal protein S6 kinase beta-12.7.11.10.457
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3gu6ADPDeath-associated protein kinase 12.7.11.10.457
3jpuTY4Transcriptional activator protein LasR/0.457
4fod0UVALK tyrosine kinase receptor2.7.10.10.457
2c5nCK8Cyclin-dependent kinase 22.7.11.220.456
2iw84SPCyclin-dependent kinase 22.7.11.220.456
2j4z626Aurora kinase A2.7.11.10.456
2uzeC95Cyclin-dependent kinase 22.7.11.220.456
3at4CCKCasein kinase II subunit alpha2.7.11.10.456
3eljGS7Mitogen-activated protein kinase 82.7.11.240.456
3gxlQIGTGF-beta receptor type-12.7.11.300.456
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3vquO22Dual specificity protein kinase TTK2.7.12.10.456
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.456
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.456
4wkqIREEpidermal growth factor receptor2.7.10.10.456
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
1m2rMNYCasein kinase II subunit alpha2.7.11.10.455
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.455
2jedLG8Protein kinase C theta type2.7.11.130.455
2pvhP19Casein kinase II subunit alpha2.7.11.10.455
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.455
3a62STURibosomal protein S6 kinase beta-12.7.11.10.455
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.455
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.455
3nynSGVG protein-coupled receptor kinase 62.7.11.160.455
3uyt0CKCasein kinase I isoform delta2.7.11.10.455
3v3vMYUMitogen-activated protein kinase 82.7.11.240.455
4bchT7ZCyclin-dependent kinase 92.7.11.220.455
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.455
4i8vBHFCytochrome P450 1A11.14.14.10.455
4j99ACPFibroblast growth factor receptor 2/0.455
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.455
1c70L75Protease/0.454
1m13HYFNuclear receptor subfamily 1 group I member 2/0.454
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.454
1ppjANYCytochrome b/0.454
1u4dDBQActivated CDC42 kinase 1/0.454
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.454
2itzIREEpidermal growth factor receptor2.7.10.10.454
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.454
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.454
2xyuQ9GEphrin type-A receptor 42.7.10.10.454
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.454
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.454
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.454
4c62XWWTyrosine-protein kinase JAK2/0.454
4hvg19QTyrosine-protein kinase JAK32.7.10.20.454
4qmySTUSerine/threonine-protein kinase 242.7.11.10.454
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.454
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.453
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.453
2ovhAS0Progesterone receptor/0.453
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.453
3gu83GUDeath-associated protein kinase 12.7.11.10.453
3nbvANPKetohexokinase/0.453
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
5cshATPCasein kinase II subunit alpha2.7.11.10.453
1zeoC01Peroxisome proliferator-activated receptor gamma/0.452
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.452
2pvyACPFibroblast growth factor receptor 2/0.452
3oqfS51Renin3.4.23.150.452
3ttjJBIMitogen-activated protein kinase 102.7.11.240.452
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.452
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.452
4fi1ATPCasein kinase II subunit alpha2.7.11.10.452
1bxoPP7Penicillopepsin-13.4.23.200.451
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.451
2j0k4STFocal adhesion kinase 12.7.10.20.451
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.451
2qo9ANPEphrin type-A receptor 32.7.10.10.451
2r43G3GGag-Pol polyprotein3.4.23.160.451
2uzlC94Cyclin-dependent kinase 22.7.11.220.451
2wecPP5Penicillopepsin-13.4.23.200.451
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.451
2zjwREFCasein kinase II subunit alpha2.7.11.10.451
3kf7L9GMitogen-activated protein kinase 14/0.451
3u4uLNHCasein kinase II subunit alpha2.7.11.10.451
4ia3BIVVitamin D3 receptor A/0.451
4kbk1QGCasein kinase I isoform delta2.7.11.10.451
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.451
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.451
4twpAXITyrosine-protein kinase ABL12.7.10.20.451
1msnJE2Gag-Pol polyprotein3.4.23.160.450
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.450
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.450
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.450
2wpa889Cyclin-dependent kinase 22.7.11.220.450
2yfxVGHALK tyrosine kinase receptor2.7.10.10.450
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.450
2zdt46CMitogen-activated protein kinase 102.7.11.240.450
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.450
4anqVGHALK tyrosine kinase receptor2.7.10.10.450
4bb3KKAIsopenicillin N synthase1.21.3.10.450
4erwSTUCyclin-dependent kinase 22.7.11.220.450
4xumIMNPeroxisome proliferator-activated receptor gamma/0.450
5auuLU2Death-associated protein kinase 12.7.11.10.450
1dawANPCasein kinase II subunit alpha2.7.11.10.449
1dayGNPCasein kinase II subunit alpha2.7.11.10.449
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.449
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.449
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.449
2i4qUA4Renin3.4.23.150.449
2ittAEEEpidermal growth factor receptor2.7.10.10.449
2w3wVG9Dihydrofolate reductase/0.449
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.449
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
3a7jADPSerine/threonine-protein kinase 242.7.11.10.449
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.449
3lixE17Protease/0.449
3rk708ZCyclin-dependent kinase 22.7.11.220.449
3vryB43Tyrosine-protein kinase HCK2.7.10.20.449
3vs1VSATyrosine-protein kinase HCK2.7.10.20.449
4b1fKRHGlutamate racemase/0.449
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.449
4g160VMCasein kinase I isoform gamma-32.7.11.10.449
4g170VNCasein kinase I isoform gamma-32.7.11.10.449
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.449
1i44ACPInsulin receptor2.7.10.10.448
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.448
1oi9N20Cyclin-dependent kinase 22.7.11.220.448
2chlDKICasein kinase I isoform gamma-32.7.11.10.448
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.448
3cgoJNOMitogen-activated protein kinase 102.7.11.240.448
3le62BZCyclin-dependent kinase 22.7.11.220.448
3linE13Protease/0.448
3mtfA3FActivin receptor type-12.7.11.300.448
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3u9eCOALmo1369 protein/0.448
4anmWULCasein kinase II subunit alpha2.7.11.10.448
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.448
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.448
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.448
1rfvADPPyridoxal kinase2.7.1.350.447
2ath3EAPeroxisome proliferator-activated receptor gamma/0.447
2c7xNRBCytochrome P450 monooxygenase PikC/0.447
2pwcG3GGag-Pol polyprotein3.4.23.160.447
2rqfJH3Hemolymph juvenile hormone binding protein/0.447
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.447
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.447
3cgfJNFMitogen-activated protein kinase 102.7.11.240.447
3eek53SUncharacterized protein/0.447
3lu8IQXSerum albumin/0.447
3mtlFEFCyclin-dependent kinase 162.7.11.220.447
3oqkS52Renin3.4.23.150.447
3uvqFS8Mitogen-activated protein kinase 14/0.447
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.447
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.447
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.447
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.447
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.447
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.447
4ux9ANPMitogen-activated protein kinase 82.7.11.240.447
4xlvACPInsulin receptor2.7.10.10.447
1d4jMSCGag-Pol polyprotein3.4.23.160.446
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1gih1PUCyclin-dependent kinase 22.7.11.220.446
1kkq471Peroxisome proliferator-activated receptor alpha/0.446
1ndzFR5Adenosine deaminase3.5.4.40.446
2b7aIZATyrosine-protein kinase JAK2/0.446
2p4yC03Peroxisome proliferator-activated receptor gamma/0.446
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.446
3qu0X40Cyclin-dependent kinase 22.7.11.220.446
4elf35IDihydrofolate reductase/0.446
4en4ATPPyridoxal kinase2.7.1.350.446
4jlm1NNDeoxycytidine kinase2.7.1.740.446
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.446
4nc3ERM5-hydroxytryptamine receptor 2B/0.446
1psa0ZLPepsin A3.4.23.10.445
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.445
2iko7IGRenin3.4.23.150.445
2lbaCHOFatty acid binding protein 6/0.445
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.445
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.445
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.445
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.445
4gxs0YSGlutamate receptor 2/0.445
4nb6444Nuclear receptor ROR-gamma/0.445
1d4hBEHGag-Pol polyprotein3.4.23.160.444
1m17AQ4Epidermal growth factor receptor2.7.10.10.444
1npa3NHGag-Pol polyprotein3.4.23.160.444
1npwLGZGag-Pol polyprotein3.4.23.160.444
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.444
2fxdDR7Pol polyprotein/0.444
2i40BLZCyclin-dependent kinase 22.7.11.220.444
2znq401Peroxisome proliferator-activated receptor delta/0.444
3bw4FMNPutative 2-nitropropane dioxygenase/0.444
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.444
3hllI45Mitogen-activated protein kinase 14/0.444
3s4qNK0Mitogen-activated protein kinase 14/0.444
3t2zFADSulfide-quinone reductase/0.444
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.444
3zze6XPHepatocyte growth factor receptor2.7.10.10.444
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.444
4a6bQG8Gag-Pol polyprotein3.4.23.160.444
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4ib4ERM5-hydroxytryptamine receptor 2B/0.444
4ryvZEAProtein LlR18A/0.444
1s9qOHTEstrogen-related receptor gamma/0.443
1y0s331Peroxisome proliferator-activated receptor delta/0.443
2eufLQQCyclin-dependent kinase 62.7.11.220.443
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.443
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
3hyoADPPyridoxal kinase/0.443
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3owl19ECasein kinase II subunit alpha2.7.11.10.443
3vt65YIVitamin D3 receptor/0.443
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.443
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.443
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.443
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.443
4iarERM5-hydroxytryptamine receptor 1B/0.443
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.443
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.443
4kba1QMCasein kinase I isoform delta2.7.11.10.443
1eh4IC1Casein kinase I homolog 12.7.11.10.442
1h1s4SPCyclin-dependent kinase 22.7.11.220.442
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1oguST8Cyclin-dependent kinase 22.7.11.220.442
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.442
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.442
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.442
2j0j4STFocal adhesion kinase 12.7.10.20.442
2qo7ANPEphrin type-A receptor 32.7.10.10.442
2vagV25Dual specificity protein kinase CLK12.7.12.10.442
3c4xATPRhodopsin kinase/0.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
1m2pHNACasein kinase II subunit alpha2.7.11.10.441
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.441
1qrpHH0Pepsin A-43.4.23.10.441
2c475IDCasein kinase I isoform gamma-2/0.441
2o0uC0MMitogen-activated protein kinase 102.7.11.240.441
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.441
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.441
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.441
4ansVGHALK tyrosine kinase receptor2.7.10.10.441
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.441
4c4g7RODual specificity protein kinase TTK2.7.12.10.441
4ips1G4Mycocyclosin synthase1.14.21.90.441
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.441
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.441
5e8xSTUTGF-beta receptor type-12.7.11.300.441
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1nq7ARLNuclear receptor ROR-beta/0.440
1x8lOXRRetinol dehydratase/0.440
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.440
2g1s4IGRenin3.4.23.150.440
2xp2VGHALK tyrosine kinase receptor2.7.10.10.440
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.440
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.440
2yxuATPPyridoxal kinase2.7.1.350.440
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.440
3flwFLWMitogen-activated protein kinase 14/0.440
3kvxFMYMitogen-activated protein kinase 102.7.11.240.440
3l8p0CEAngiopoietin-1 receptor2.7.10.10.440
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3lctADPALK tyrosine kinase receptor2.7.10.10.440
3livE16Protease/0.440
3sheI85MAP kinase-activated protein kinase 32.7.11.10.440
3tnwF18Cyclin-dependent kinase 22.7.11.220.440
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.440
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.440
4dgo0JWCasein kinase II subunit alpha2.7.11.10.440
4e730NRMitogen-activated protein kinase 82.7.11.240.440
4hge15VTyrosine-protein kinase JAK2/0.440
4jkt04AGlutaminase kidney isoform, mitochondrial3.5.1.20.440
4jlj1NMDeoxycytidine kinase2.7.1.740.440
4uxq0LIFibroblast growth factor receptor 42.7.10.10.440