sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 1.000 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.576 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.522 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.503 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.498 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.498 | |
| 2huq | SAH | Diphthine synthase | / | 0.495 | |
| 1wng | SAH | Diphthine synthase | / | 0.490 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.489 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.487 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.485 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.485 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.485 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.483 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.481 | |
| 2e07 | SAH | Diphthine synthase | / | 0.479 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.477 | |
| 2e16 | SAH | Diphthine synthase | / | 0.476 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.475 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.474 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.474 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.474 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.474 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.473 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.473 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.472 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.471 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.471 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.471 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.470 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.470 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.469 | |
| 2p9d | SAH | Diphthine synthase | / | 0.469 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.469 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.469 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.469 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2dek | SAH | Diphthine synthase | / | 0.468 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.468 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.468 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.467 | |
| 2ejj | SAH | Diphthine synthase | / | 0.467 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.466 | |
| 2p5c | SAH | Diphthine synthase | / | 0.466 | |
| 2z6r | SAH | Diphthine synthase | / | 0.465 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.465 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.465 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 2egl | SAH | Diphthine synthase | / | 0.464 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.464 | |
| 4l9k | EHF | Serum albumin | / | 0.464 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.464 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.463 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.463 | |
| 4e5p | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.463 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.463 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.462 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.462 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.461 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.461 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.461 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.461 | |
| 4h6p | FMN | Chromate reductase | / | 0.461 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.461 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.461 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.460 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.460 | |
| 2e17 | SAH | Diphthine synthase | / | 0.459 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.459 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.459 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.459 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.459 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1p0f | NAP | NADP-dependent alcohol dehydrogenase | 1.1.1.2 | 0.458 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.458 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.458 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.458 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.458 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.458 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.458 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.458 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.458 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.457 | |
| 2en5 | SAH | Diphthine synthase | / | 0.457 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.457 | |
| 2hux | SAH | Diphthine synthase | / | 0.457 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.457 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.457 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.457 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.457 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.456 | |
| 2bxm | IMN | Serum albumin | / | 0.456 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.456 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.456 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.456 | |
| 2owu | SAH | Diphthine synthase | / | 0.456 | |
| 2p6i | SAH | Diphthine synthase | / | 0.456 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.456 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.456 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.456 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.456 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.455 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.455 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.455 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.455 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.455 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 2dxv | SAH | Diphthine synthase | / | 0.454 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 2huv | SAH | Diphthine synthase | / | 0.454 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.454 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.454 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.454 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.453 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.453 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 2e8q | SAH | Diphthine synthase | / | 0.453 | |
| 2p5f | SAH | Diphthine synthase | / | 0.453 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.453 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 2y3s | TIR | TamL | / | 0.452 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.452 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.452 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.451 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.451 | |
| 2p2x | SAH | Diphthine synthase | / | 0.451 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.451 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.451 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 3gob | HXX | DdmC | / | 0.451 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.451 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.451 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.451 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.450 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.450 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.450 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.450 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.450 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.450 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.450 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.450 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.450 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.449 | |
| 1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.449 | |
| 1r2j | FAD | FkbI | / | 0.449 | |
| 2el0 | SAH | Diphthine synthase | / | 0.449 | |
| 2owg | SAH | Diphthine synthase | / | 0.449 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.449 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.449 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.449 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.449 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.449 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.448 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.448 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.448 | |
| 2e08 | SAH | Diphthine synthase | / | 0.448 | |
| 2e4n | SAH | Diphthine synthase | / | 0.448 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.448 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.448 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.448 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.448 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.447 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.447 | |
| 2d2i | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2dsh | SAH | Diphthine synthase | / | 0.447 | |
| 2dxw | SAH | Diphthine synthase | / | 0.447 | |
| 2el3 | SAH | Diphthine synthase | / | 0.447 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.447 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.447 | |
| 2xvv | 9DN | Serum albumin | / | 0.447 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 4boy | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.447 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.447 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.447 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.446 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.446 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.446 | |
| 2ejz | SAH | Diphthine synthase | / | 0.446 | |
| 2hut | SAH | Diphthine synthase | / | 0.446 | |
| 2ohv | NHL | Glutamate racemase | / | 0.446 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.446 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.446 | |
| 4hxy | NDP | Plm1 | / | 0.446 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.446 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2dsi | SAH | Diphthine synthase | / | 0.445 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.445 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.445 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.445 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.445 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.445 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.445 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.445 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.444 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.444 | |
| 3eks | CY9 | Actin-5C | / | 0.444 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.444 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.444 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.444 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.444 | |
| 4l4x | NDP | AmphI | / | 0.444 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.444 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.444 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.444 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.443 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.443 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.443 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.443 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.443 | |
| 2ybo | SAH | Methyltransferase | / | 0.443 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3eku | CY9 | Actin-5C | / | 0.443 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.443 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.443 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.443 | |
| 4qec | NAP | ElxO | / | 0.443 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.442 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2eeq | SAH | Diphthine synthase | / | 0.442 | |
| 2emu | SAH | Diphthine synthase | / | 0.442 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2pch | SAH | Diphthine synthase | / | 0.442 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.442 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.442 | |
| 3s8c | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.442 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.441 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.441 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.441 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.441 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.441 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 3a3g | DLZ | Lumazine protein | / | 0.441 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.441 | |
| 5eox | ADP | Type 4 fimbrial biogenesis protein PilM | / | 0.441 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.441 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.440 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.440 | |
| 2egs | SAH | Diphthine synthase | / | 0.440 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.440 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.440 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 |