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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1w5t ANP ORC1-type DNA replication protein 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1w5t ANPORC1-type DNA replication protein 2 / 1.235
1w5s ADPORC1-type DNA replication protein 2 / 0.993
1w5t ADPORC1-type DNA replication protein 2 / 0.945
1fnn ADPORC1-type DNA replication protein / 0.920
3oes GNPGTPase RhebL1 / 0.877
2fna ADPUncharacterized protein / 0.853
4pao GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.852
5dif GNPGTP-binding nuclear protein Ran / 0.848
2c5l GTPGTPase HRas / 0.847
1gia GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.846
3cx8 GSPGuanine nucleotide-binding protein subunit alpha-13 / 0.845
3rab GNPRas-related protein Rab-3A / 0.845
4g0n GNPGTPase HRas / 0.845
5l3s GNPSignal recognition particle receptor FtsY / 0.840
1xtr GNPGTP-binding protein Rheb / 0.835
3pit GNPRas-related protein M-Ras / 0.834
3ddc GNPGTPase HRas / 0.833
3a58 GNPGTP-binding protein RHO1 / 0.832
3kko GNPRas-related protein M-Ras / 0.831
3lbn GNPGTPase HRas / 0.831
3mjh GTPRas-related protein Rab-5A / 0.831
4kvg GTPRas-related protein Rap-1A / 0.830
5dha GNPGTP-binding nuclear protein Ran / 0.829
3l8y GNPGTPase HRas / 0.828
1n6l GTPRas-related protein Rab-5A / 0.827
3dt4 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.827
4dlz GNPGTPase HRas / 0.827
4rkf GNPRas-related protein Rab-3 / 0.827
4qm6 GTPMetallophosphoesterase / 0.823
2ck3 ANPATP synthase subunit alpha, mitochondrial / 0.822
2ck3 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.822
1z0d GDPRas-related protein Rab-5C / 0.821
3b1x GNPFerrous iron transport protein B / 0.821
1cs4 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.820
2ffq GSPRas-related protein Rab-6B / 0.819
1azt GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.817
3adc ANPL-seryl-tRNA(Sec) kinase 2.7.1.164 0.817
3zia ATPATP synthase subunit alpha, mitochondrial / 0.817
4o25 GTPGTP-binding protein Rheb / 0.817
5l3r GCPCell division protein FtsY homolog, chloroplastic / 0.817
1kmq GNPTransforming protein RhoA / 0.816
3k9l GNPGTPase HRas / 0.816
3oiv GNPGTPase HRas / 0.815
3oiw GNPGTPase HRas / 0.815
3tgp GNPGTPase HRas / 0.815
4dlw GNPGTPase HRas / 0.815
1g17 GNPRas-related protein SEC4 / 0.814
2ov2 GCPRas-related C3 botulinum toxin substrate 3 / 0.814
3i3s GNPGTPase HRas / 0.814
3k8y GNPGTPase HRas / 0.814
3oiu GNPGTPase HRas / 0.814
3rs0 GNPGTPase HRas / 0.814
3rs4 GNPGTPase HRas / 0.814
3rs5 GNPGTPase HRas / 0.814
3rs7 GNPGTPase HRas / 0.814
4dlt GNPGTPase HRas / 0.814
4dlv GNPGTPase HRas / 0.814
2rgb GNPGTPase HRas / 0.813
3rsl GNPGTPase HRas / 0.813
4dls GNPGTPase HRas / 0.813
4l9w GNPGTPase HRas / 0.813
4tl6 ANPCircadian clock protein kinase KaiC 2.7.11.1 0.813
3v4f GNPGTPase HRas / 0.812
4hdo GNPRas-related protein Rap-1b / 0.812
5b2z GNPGTPase HRas / 0.812
3wyf GTPGTP-binding nuclear protein / 0.811
4dlx GNPGTPase HRas / 0.811
4nyj GNPGTPase HRas / 0.811
4lhw GNPRas-related protein Rab-8A / 0.810
3lbh GNPGTPase HRas / 0.809
1esn ANPPantothenate kinase 2.7.1.33 0.808
2j7p GNPSignal recognition particle protein / 0.807
2j7p GNPSignal recognition particle receptor FtsY / 0.807
4dsn GCPGTPase KRas / 0.807
2x2r ADPKinesin-like protein KIF11 / 0.806
3vx4 ATPPutative ABC transporter, ATP-binding protein ComA / 0.806
1uad GNPRas-related protein Ral-A / 0.805
1zcb GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.804
2r9v ATPATP synthase subunit alpha / 0.804
1bmf ANPATP synthase subunit alpha, mitochondrial / 0.803
1bmf ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.803
3dt2 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.803
2xtz GSPGuanine nucleotide-binding protein alpha-1 subunit / 0.802
3oeh ANPATP synthase subunit alpha, mitochondrial / 0.802
3th5 GNPRas-related C3 botulinum toxin substrate 1 / 0.802
1wdt GTPElongation factor G (EF-G-2) / 0.800
3sbd GNPRas-related C3 botulinum toxin substrate 1 / 0.800
3x1z GNPRas-related protein Rap-1b / 0.800
5aun ADPIron-sulfur cluster carrier protein / 0.800
2rgg GNPGTPase HRas / 0.799
1p3d ANPUDP-N-acetylmuramate--L-alanine ligase 6.3.2.8 0.798
2gil GTPRas-related protein Rab-6A / 0.798
1gwn GTPRho-related GTP-binding protein RhoE / 0.797
2fe4 GDPRas-related protein Rab-6B / 0.797
4dso GSPGTPase KRas / 0.797
1mh1 GNPRas-related C3 botulinum toxin substrate 1 / 0.796
1t91 GTPRas-related protein Rab-7a / 0.796
2rgc GNPGTPase HRas / 0.796
3tso GNPRas-related protein Rab-25 / 0.796
4xvq GNPGTPase HRas / 0.796
1cul GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.795
1bof GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.794
2gvd GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.794
2qtv GNPSmall COPII coat GTPase SAR1 3.6.5 0.793
2x7e ADPKinesin-like protein KIF11 / 0.793
1e79 ATPATP synthase subunit alpha, mitochondrial / 0.792
1e79 ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.792
2qme GCPRas-related C3 botulinum toxin substrate 3 / 0.792
4asu ADPATP synthase subunit alpha, mitochondrial / 0.792
1ank ANPAdenylate kinase / 0.791
2jiz ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.791
2pg2 ADPKinesin-like protein KIF11 / 0.791
4jl5 ADPAdenylate kinase / 0.791
4lhv GDPRas-related protein Rab-8A / 0.791
5k5z ANPUncharacterized protein / 0.791
1w0k ADPATP synthase subunit alpha, mitochondrial / 0.789
1w0k ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.789
2jj2 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.788
4tl7 ATPCircadian clock protein kinase KaiC 2.7.11.1 0.788
4x8o AP5Adenylate kinase / 0.788
1tu3 GNPRas-related protein Rab-5A / 0.787
4xoi GTPTransforming protein RhoA / 0.787
5ftc ADPTPR domain protein / 0.787
1gil GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.786
5fl3 ADPPili retraction protein PilT / 0.786
3law GNPRas-related protein Rab-7a / 0.784
4js0 GNPCell division control protein 42 homolog / 0.784
2rge GNPGTPase HRas / 0.783
1ky2 GNPGTP-binding protein YPT7 / 0.782
2v7q ATPATP synthase subunit alpha, mitochondrial / 0.782
2v7q ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.782
4x8l AP5Adenylate kinase / 0.782
1s1c GNPTransforming protein RhoA / 0.781
1zc4 GNPRas-related protein Ral-A / 0.781
1zd9 GDPADP-ribosylation factor-like protein 8A / 0.781
1z2c GNPRho-related GTP-binding protein RhoC / 0.780
1e79 ADPATP synthase subunit alpha, mitochondrial / 0.779
1e79 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.779
1wa5 GTPGTP-binding nuclear protein Ran / 0.779
3lbi GNPGTPase HRas / 0.779
3qbt GNPRas-related protein Rab-8A / 0.779
1ake AP5Adenylate kinase / 0.778
1d5c GDPGTPase (Rab6) / 0.778
1ibr GNPGTP-binding nuclear protein Ran / 0.777
3bos CDPRegulatory inactivation of DnaA Hda protein / 0.777
4nh0 ATPESX secretion system protein EccC / 0.777
4o2l GTPGTP-binding protein Rheb / 0.777
4tlc AGSCircadian clock protein kinase KaiC 2.7.11.1 0.777
3bc1 GNPRas-related protein Rab-27A / 0.776
3m0e ATPTranscriptional regulator (NtrC family) / 0.775
4cf7 ADPAdenylate kinase / 0.775
4dsu GDPGTPase KRas / 0.775
2ic5 GNPRas-related C3 botulinum toxin substrate 3 / 0.774
2hf8 GSPProbable hydrogenase nickel incorporation protein HypB / 0.773
2jj2 ADPATP synthase subunit alpha, mitochondrial / 0.773
2jj2 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.773
4k81 GTPGTPase HRas / 0.773
4ohv ANPProtein clpf-1 / 0.773
1rj9 GCPSignal recognition particle receptor FtsY / 0.772
4q02 GDPGTPase KRas / 0.772
4ql3 GDPGTPase KRas / 0.772
4tq9 GDPGTPase KRas / 0.772
2ce2 GDPGTPase HRas / 0.771
2xae ADPKinesin-like protein KIF11 / 0.771
4q03 GDPGTPase KRas / 0.771
4wa7 GDPGTPase KRas / 0.771
1m7b GTPRho-related GTP-binding protein RhoE / 0.770
3c41 ANPAmino acid ABC transporter / 0.769
3bbp GTPRas-related protein Rab-6A / 0.768
3cx6 GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.768
1got GDPGuanine nucleotide-binding protein G(t) subunit alpha-1 / 0.767
2zts ADPUncharacterized protein / 0.767
4l8g GDPGTPase KRas / 0.767
4pjj ADPUnconventional myosin-VI / 0.767
1mma ADPMyosin-2 heavy chain / 0.766
1wbb ADPDNA mismatch repair protein MutS / 0.766
2bku GTPGTP-binding nuclear protein Ran / 0.766
2c9c ATPPsp operon transcriptional activator / 0.766
4idn GNPAtlastin-1 3.6.5 0.766
4v02 ATPSite-determining protein / 0.766
1z2a GDPRas-related protein Rab-23 / 0.765
4pan GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.765
2ic5 GDPRas-related C3 botulinum toxin substrate 3 / 0.764
3tlx ADPAdenylate kinase 2 / 0.764
4l9s GDPGTPase HRas / 0.764
4lv6 GDPGTPase KRas / 0.764
4pjk ADPMyosin-2 heavy chain / 0.764
4qxa GTPRas-related protein Rab-9A / 0.764
4xsg GSPTransforming protein RhoA / 0.764
1jx2 ADPMyosin-2 heavy chain / 0.763
1yu9 GNPRas-related protein Rab-4A / 0.763
4hse ADPChaperone protein ClpB / 0.763
2bc9 GNPGuanylate-binding protein 1 / 0.762
1z0a GDPRas-related protein Rab-2A / 0.761
1oix GDPRas-related protein Rab-11A / 0.760
2cls GTPRho-related GTP-binding protein Rho6 / 0.760
2uyi ADPKinesin-like protein KIF11 / 0.760
4ike ADPAdenylate kinase / 0.760
4jl6 ADPAdenylate kinase / 0.760
4obe GDPGTPase KRas / 0.760
2j0v GDPRac-like GTP-binding protein ARAC7 / 0.759
2y65 ADPKinesin heavy chain / 0.759
1ow3 GDPTransforming protein RhoA / 0.758
1khb GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.757
3l9h ADPKinesin-like protein KIF11 / 0.757
4cvl ACPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.757
4ww4 ADPRuvB-like helicase / 0.757
1e1q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.756
1cxz GSPTransforming protein RhoA / 0.755
1fmw ATPMyosin-2 heavy chain / 0.755
1x1r GDPRas-related protein M-Ras / 0.755
4ihq ADPConserved Archaeal protein / 0.755
2jlr ANPGenome polyprotein 3.4.21.91 0.754
2q3f GNPRas-related GTP-binding protein D / 0.754
4jld ADPAdenylate kinase / 0.754
4ldj GDPGTPase KRas / 0.754
1u0h GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.753
2gks ADPProbable bifunctional SAT/APS kinase 2.7.1.25 0.753
4yqf GDPSeptin-9 / 0.753
1k5d GNPGTP-binding nuclear protein Ran / 0.752
1zc3 GNPRas-related protein Ral-A / 0.752
2gm1 ADPKinesin-like protein KIF11 / 0.752
4cym GCPRas-related protein Rab-32 / 0.752
1vg8 GNPRas-related protein Rab-7a / 0.750
1z0f GDPRas-related protein Rab-14 / 0.750
2eck ADPAdenylate kinase / 0.750
3q9l ATPSeptum site-determining protein MinD / 0.750
4epw GDPGTPase KRas / 0.750
4qos ADPPsp operon transcriptional activator / 0.750
4z54 GDPNeuronal-specific septin-3 / 0.750
2p2l GDPRas-related C3 botulinum toxin substrate 1 / 0.749
3oee ANPATP synthase subunit alpha, mitochondrial / 0.748
3oee ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.748
4epx GDPGTPase KRas / 0.748
3x1w GDPRas-related protein Rap-1b / 0.747
4c0b ATPmRNA cleavage and polyadenylation factor CLP1 / 0.747
1e1q ANPATP synthase subunit alpha, mitochondrial / 0.746
1e1q ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.746
1lfd GNPGTPase HRas / 0.746
2hld ANPATP synthase subunit alpha, mitochondrial / 0.746
2hld ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.746
3kuc GDPRas-related protein Rap-1A / 0.746
3q5d GDPAtlastin-1 3.6.5 0.746
5jlj GNPGTP-binding nuclear protein Ran / 0.746
2j5x GSPADP-ribosylation factor 6 / 0.745
3fmo ADPATP-dependent RNA helicase DDX19B 3.6.4.13 0.745
3kz1 GSPTransforming protein RhoA / 0.745
4oi4 ATPmRNA cleavage and polyadenylation factor CLP1 / 0.745
1sdm ADPKinesin heavy chain-like protein / 0.744
3ftq GNPSeptin-2 / 0.744
4zca ADPKinesin-like protein KIF11 / 0.744
1bmf ADPATP synthase subunit alpha, mitochondrial / 0.743
1bmf ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.743
3kud GDPGTPase HRas / 0.743
3myk ANPMyosin-2 heavy chain / 0.743
4tl8 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.743
5bn3 ADPV-type ATP synthase alpha chain / 0.742
5bn3 ADPNEQ263 / 0.742
2j0s ANPEukaryotic initiation factor 4A-III 3.6.4.13 0.741
3zvm ADPBifunctional polynucleotide phosphatase/kinase 2.7.1.78 0.741
4jlo ADPAdenylate kinase / 0.741
1r0z ATPCystic fibrosis transmembrane conductance regulator / 0.740
2c96 ATPPsp operon transcriptional activator / 0.740
2g1q ADPKinesin-like protein KIF11 / 0.740
2olr ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.740
4hdq GNPRas-related protein Rap-1b / 0.740
4xvu ATPATPase GET3 / 0.740
1yrs ADPKinesin-like protein KIF11 / 0.738
2c9o ADPRuvB-like 1 3.6.4.12 0.738
4b7b ADPKinesin-like protein KIF11 / 0.738
4idp GNPAtlastin-1 3.6.5 0.738
2zpa ADPtRNA(Met) cytidine acetyltransferase TmcA / 0.737
3zfd ANPChromosome-associated kinesin KIF4 / 0.737
4y0v GDPADP-ribosylation factor 1, putative / 0.737
4ylg GDPADP-ribosylation factor 1, putative / 0.737
1gp2 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.736
2o8b ADPDNA mismatch repair protein Msh2 / 0.736
2qen ADPWalker-Type ATPase / 0.736
3tkl GTPRas-related protein Rab-1A / 0.736
4lpk GDPGTPase KRas / 0.736
5cyo GDPSeptin-9 / 0.736
1ny5 ADPTranscriptional regulator (NtrC family) / 0.735
2zfi ADPKinesin-like protein KIF1A / 0.735
3onw GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.735
1zbd GTPRas-related protein Rab-3A / 0.734
3r9i ADPSeptum site-determining protein MinD / 0.734
4g5q GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.734
5irn ADPNucleotide binding oligomerization domain containing 2 / 0.733
2bme GNPRas-related protein Rab-4A / 0.732
3e5h GNPRas-related protein Rab-28 / 0.732
3k1j ADPATP-dependent protease Lon / 0.732
3pfi ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.732
4luc GDPGTPase KRas / 0.732
4m0l GDPTranslation initiation factor 2 subunit gamma / 0.732
3cob ADPKinesin heavy chain-like protein / 0.731
4pk4 ADPUnconventional myosin-VI / 0.731
4tla ADPCircadian clock protein kinase KaiC 2.7.11.1 0.731
1e96 GTPRas-related C3 botulinum toxin substrate 1 / 0.730
1f5n GNPGuanylate-binding protein 1 / 0.730
4bzq ADPBifunctional enzyme CysN/CysC 2.7.1.25 0.730
2fg5 GNPRas-related protein Rab-31 / 0.729
2ql6 ADPNicotinamide riboside kinase 1 / 0.729
3kkq GDPRas-related protein M-Ras / 0.729
3tnf GNPRas-related protein Rab-8A / 0.729
3k3b ADPKinesin-like protein KIF11 / 0.728
4jky ADPAdenylate kinase / 0.728
3bb3 GDPTranslocase of chloroplast 33, chloroplastic 3.6.5 0.727
4iei ADPGene 2 protein / 0.727
4nyi GNPGTPase HRas / 0.727
4qnr ATPPsp operon transcriptional activator / 0.727
2w2v GTPRas-related C3 botulinum toxin substrate 2 / 0.726
4o2r GDPGTP-binding protein Rheb / 0.726
4tl9 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.726
4tld AGSCircadian clock protein kinase KaiC 2.7.11.1 0.726
2cl6 CAGGTPase HRas / 0.725
3hu1 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.725
1a2b GSPTransforming protein RhoA / 0.724
4goj GNPADP-ribosylation factor-like protein 3 / 0.724
4uj3 GNPRas-related protein Rab-11A / 0.724
1v8k ANPKinesin-like protein KIF2C / 0.723
3d8b ADPFidgetin-like protein 1 3.6.4 0.723
3qe0 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.723
4jsy GTPMetallophosphoesterase / 0.723
1gqy ACPUDP-N-acetylmuramate--L-alanine ligase 6.3.2.8 0.722
1xef ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.722
4db1 ANPMyosin-7 / 0.722
1ofh ADPATP-dependent protease ATPase subunit HslU / 0.721
1w1w AGSStructural maintenance of chromosomes protein 1 / 0.721
3vhx GTPADP-ribosylation factor 6 / 0.721
1okk GCPSignal recognition particle protein / 0.720
1okk GCPSignal recognition particle receptor FtsY / 0.720
2olq ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.720
1ohh ANPATP synthase subunit alpha, mitochondrial / 0.719
1ohh ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.719
1rrg GDPADP-ribosylation factor 1 / 0.719
1h8h ATPATP synthase subunit alpha, mitochondrial / 0.718
1h8h ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.718
1mmg AGSMyosin-2 heavy chain / 0.718
1ii6 ADPKinesin-like protein KIF11 / 0.717
2g0n GDPRas-related C3 botulinum toxin substrate 3 / 0.717
3cph GDPRas-related protein SEC4 / 0.717
3wyg GTPGTP-binding nuclear protein GSP1/CNR1 / 0.717
3a4l ANPL-seryl-tRNA(Sec) kinase 2.7.1.164 0.716
4oi2 ADPProtein clpf-1 / 0.716
1aq2 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.715
2q2z ADPKinesin-like protein KIF11 / 0.715
3c16 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.715
3eg5 GNPCell division control protein 42 homolog / 0.715
3hqd ANPKinesin-like protein KIF11 / 0.715
1g6o ADPCag alpha / 0.714
1svl ADPLarge T antigen 3.6.4 0.714
3ref GDPRho family GTPase / 0.714
4bec ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.714
4itr GDPCell division control protein 42 homolog / 0.714
3mle ADPATP-dependent dethiobiotin synthetase BioD 6.3.3.3 0.713
1xmv ADPProtein RecA / 0.712
4dvg GSPRho family GTPase / 0.712
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.711
3r9x GNPGTPase Era / 0.711
4d81 ADPAAA ATPase, central domain protein / 0.711
4ohx ADPProtein clpf-1 / 0.711
4g01 GDPRas-related protein RABF2b / 0.710
1l8q ADPChromosomal replication initiator protein DnaA / 0.708
2fl2 ADPKinesin-like protein KIF11 / 0.708
1xms ANPProtein RecA / 0.707
3moh GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.707
2dr3 ADPUPF0273 protein PH0284 / 0.706
3qcz ANPDihydrofolate synthase/folylpolyglutamate synthase / 0.706
4be7 ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.706
4cid ANPEH domain-containing protein 2 / 0.706
2v1x ADPATP-dependent DNA helicase Q1 3.6.4.12 0.705
4kln AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.705
5c46 GSPRas-related protein Rab-11A / 0.703
5hpy GDPTransforming protein RhoA / 0.703
1nly AGSCag alpha / 0.702
2dwp ACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2.7.1.105 0.702
2jiz ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.702
4ag5 ADPType IV secretory pathway VirB4 components-like protein / 0.702
1ayl ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.701
2db3 ANPATP-dependent RNA helicase vasa, isoform A 3.6.4.13 0.701
4pfp ADPUnconventional myosin-VI / 0.701
4r43 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.701
3fkq ATPNtrC-like two-domain protein / 0.700
4gp6 ADPMetallophosphoesterase / 0.700
4tle AGSCircadian clock protein kinase KaiC 2.7.11.1 0.700
2gcp GSPRho-related GTP-binding protein RhoC / 0.699
2l0x GDPGTP-binding protein Rheb / 0.698
3hu2 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.698
5d3q GDPDynamin-1 3.6.5.5 0.697
1g16 GDPRas-related protein SEC4 / 0.696
4ap0 ADPKinesin-like protein KIF11 / 0.696
4qbi AP5Adenylate kinase / 0.696
3c14 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.695
2fju GSPRas-related C3 botulinum toxin substrate 1 / 0.694
3hu3 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.694
4lrw GDPGTPase KRas / 0.694
1im2 ADPATP-dependent protease ATPase subunit HslU / 0.693
1sxj AGSReplication factor C subunit 1 / 0.693
4d0l GSPRas-related protein Rab-11A / 0.693
4hi0 GDPUrease accessory protein UreG / 0.693
4ww0 ADPATP-dependent zinc metalloprotease FtsH / 0.693
1svm ATPLarge T antigen 3.6.4 0.692
3fvq ATPFe(3+) ions import ATP-binding protein FbpC / 0.691
3zl8 ADPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.691
4a28 ADPKinesin-like protein KIF11 / 0.691
4cvm ANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.691
4ncl GDPEukaryotic translation initiation factor 5B / 0.691
4c2u ANPDNA helicase / 0.690
2dpx GDPGTP-binding protein RAD / 0.688
3hpr AP5Adenylate kinase / 0.688
1m2o GNPSmall COPII coat GTPase SAR1 3.6.5 0.687
4c30 ANPDNA helicase / 0.687
2xau ADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 3.6.4.13 0.686
3jvv ACPTwitching mobility protein / 0.685
3pyz ANPDihydrofolate synthase/folylpolyglutamate synthase / 0.685
3w3z GTPGTP-binding nuclear protein Ran / 0.685
1am4 GNPCell division control protein 42 homolog / 0.684
2v7q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.684
4xvr GNPGTPase HRas / 0.684
1j7k ATPHolliday junction ATP-dependent DNA helicase RuvB / 0.683
4a1z ADPKinesin-like protein KIF11 / 0.683
1xkv ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.682
3nbx ADPATPase RavA 3.6.3 0.682
3t1t GDPProbable gliding protein mglA / 0.682
4r9u ANPVitamin B12 import ATP-binding protein BtuD / 0.682
1in5 ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.681
2zrj AGSProtein RecA / 0.681
2bbw GP5Adenylate kinase 4, mitochondrial / 0.680
3nbz GTPGTP-binding nuclear protein Ran / 0.680
4uj5 GNPRas-related protein Rab-11A / 0.680
3ums GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.679
4ko8 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.679
2py7 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.678
3sqw ANPATP-dependent RNA helicase MSS116, mitochondrial 3.6.4.13 0.678
4mit GTPRho-related protein racC / 0.678
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.677
3ea5 GDPGTP-binding nuclear protein Ran / 0.677
3sop GDPNeuronal-specific septin-3 / 0.677
4cei ANPATP-dependent helicase/deoxyribonuclease subunit B 3.1 0.677
1a4r GNHCell division control protein 42 homolog / 0.676
1e0j ANPDNA primase/helicase 2.7.7 0.676
4ys0 ADPProtein translocase subunit SecA / 0.676
1sq5 ADPPantothenate kinase 2.7.1.33 0.675
4ki0 ANPMaltose/maltodextrin import ATP-binding protein MalK / 0.674
1nsf ATPVesicle-fusing ATPase 3.6.4.6 0.673
1yzq GNPRas-related protein Rab-6A / 0.673
4jjz ADPFormate--tetrahydrofolate ligase / 0.673
2dft ADPShikimate kinase 2.7.1.71 0.672
2jj1 ANPATP synthase subunit alpha, mitochondrial / 0.672
4yer ADPAntibiotic ABC transporter, ATP-binding protein, putative / 0.671
5ftf ADPTPR domain protein / 0.671
1q3h ANPCystic fibrosis transmembrane conductance regulator / 0.669
1p9w ANPType II secretion system protein E / 0.668
2bif ANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 2.7.1.105 0.668
3l1c ADPProtein claret segregational / 0.668
1w7k ADPDihydrofolate synthase/folylpolyglutamate synthase 6.3.2.12 0.667
4dxa GSPRas-related protein Rap-1b / 0.667
5cyp GSPSeptin-9 / 0.667
1njf ADPDNA polymerase III subunit tau 2.7.7.7 0.666
3tqc ADPPantothenate kinase / 0.666
4wou GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.665
1xd9 ADPNitrogenase iron protein 1 1.18.6.1 0.664
2vor ACPFolylpolyglutamate synthase / 0.664
5i67 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.664
2iut AGSDNA translocase FtsK / 0.663
2vos ADPFolylpolyglutamate synthase / 0.662
4wpu GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.662
2npi ATPmRNA cleavage and polyadenylation factor CLP1 / 0.661
3b05 IPEIsopentenyl-diphosphate delta-isomerase / 0.661
4iok ADPFormate--tetrahydrofolate ligase / 0.661
4tnr DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.661
1z6t ADPApoptotic protease-activating factor 1 / 0.660
4a51 ADPKinesin-like protein KIF11 / 0.659
1oyy AGSATP-dependent DNA helicase RecQ 3.6.4.12 0.658
3tjz GNPADP-ribosylation factor 1 / 0.658
1h65 GDPTranslocase of chloroplast 34 3.6.5 0.655
1njf AGSDNA polymerase III subunit tau 2.7.7.7 0.655
4xjx ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.655
3pcr GTPADP-ribosylation factor 6 / 0.654
1i4l GDPRas-related C3 botulinum toxin substrate 1 / 0.652
2axn ADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 / 0.652
2xtn GTPGTPase IMAP family member 2 / 0.652
3t3f N5PDNA polymerase I, thermostable 2.7.7.7 0.652
4gzl GNPRas-related C3 botulinum toxin substrate 1 / 0.652
4ohw ATPProtein clpf-1 / 0.652
5itz GTPTubulin alpha-1B chain / 0.652
1e32 ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.651
1z5v GSPTubulin gamma-1 chain / 0.650
2xsz ATPRuvB-like 2 3.6.4.12 0.650