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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.11.000
1eh4IC1Casein kinase I homolog 12.7.11.10.545
3tkuM77Serine/threonine-protein kinase MRCK beta2.7.11.10.522
2jedLG8Protein kinase C theta type2.7.11.130.519
4ic7ANPMitogen-activated protein kinase 72.7.11.240.519
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.518
1g5sI17Cyclin-dependent kinase 22.7.11.220.513
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
4bgg844Activin receptor type-12.7.11.300.513
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.509
1h1r6CPCyclin-dependent kinase 22.7.11.220.507
4hvi19STyrosine-protein kinase JAK32.7.10.20.507
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.505
4dgnLU2Casein kinase II subunit alpha2.7.11.10.501
4eon1ROCyclin-dependent kinase 22.7.11.220.501
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.501
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
4dymIYZActivin receptor type-12.7.11.300.498
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
3mtfA3FActivin receptor type-12.7.11.300.497
3ncz3NCRho-associated protein kinase 12.7.11.10.497
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.496
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.496
4g170VNCasein kinase I isoform gamma-32.7.11.10.496
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.496
1oiuN76Cyclin-dependent kinase 22.7.11.220.495
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2pvhP19Casein kinase II subunit alpha2.7.11.10.495
3w33W19Epidermal growth factor receptor2.7.10.10.495
1py5PY1TGF-beta receptor type-12.7.11.300.494
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
2eufLQQCyclin-dependent kinase 62.7.11.220.494
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.493
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.493
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.492
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.491
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.491
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.491
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.490
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.490
2pvnP63Casein kinase II subunit alpha2.7.11.10.490
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
4dgo0JWCasein kinase II subunit alpha2.7.11.10.490
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.490
3uyt0CKCasein kinase I isoform delta2.7.11.10.489
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.489
4hvh19RTyrosine-protein kinase JAK32.7.10.20.489
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.488
3w32W32Epidermal growth factor receptor2.7.10.10.488
1m2qMNXCasein kinase II subunit alpha2.7.11.10.487
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.487
4yuqKS1Calmodulin-like domain protein kinase/0.487
5e8wSTUTGF-beta receptor type-12.7.11.300.487
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.485
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.485
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.482
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
1di8DTQCyclin-dependent kinase 22.7.11.220.481
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.481
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.481
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.481
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.480
3zh8C58Protein kinase C iota type2.7.11.130.480
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.479
4g160VMCasein kinase I isoform gamma-32.7.11.10.479
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.478
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2xa4AZ5Tyrosine-protein kinase JAK2/0.478
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.478
4c02TAKActivin receptor type-12.7.11.300.478
1oi9N20Cyclin-dependent kinase 22.7.11.220.477
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
1u4dDBQActivated CDC42 kinase 1/0.477
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.477
4bcoT6QCyclin-dependent kinase 22.7.11.220.477
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3hmm855TGF-beta receptor type-12.7.11.300.476
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.476
4othDRNSerine/threonine-protein kinase N1/0.476
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2x1nX1NCyclin-dependent kinase 22.7.11.220.475
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.475
4otiMI1Serine/threonine-protein kinase N1/0.475
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.474
2uzbC75Cyclin-dependent kinase 22.7.11.220.474
3be9P04Casein kinase II subunit alpha2.7.11.10.474
3slkNDPPolyketide synthase extender module 2/0.474
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.474
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.473
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
2xikJ60Serine/threonine-protein kinase 252.7.11.10.473
1dyrTOPDihydrofolate reductase1.5.1.30.472
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
1vjy460TGF-beta receptor type-12.7.11.300.472
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.472
2ijmADPFocal adhesion kinase 12.7.10.20.472
4gk2L66Ephrin type-A receptor 32.7.10.10.472
1h1s4SPCyclin-dependent kinase 22.7.11.220.471
1m2rMNYCasein kinase II subunit alpha2.7.11.10.471
3hllI45Mitogen-activated protein kinase 14/0.471
3lq5SLQCyclin-dependent kinase 92.7.11.220.471
4anmWULCasein kinase II subunit alpha2.7.11.10.471
4jia1K3Tyrosine-protein kinase JAK2/0.471
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.471
4riyADPEpidermal growth factor receptor2.7.10.10.471
2etrY27Rho-associated protein kinase 12.7.11.10.470
4aacAAVMitogen-activated protein kinase 14/0.470
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4e4m0NHTyrosine-protein kinase JAK2/0.470
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
2j0m4STFocal adhesion kinase 12.7.10.20.469
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4kbk1QGCasein kinase I isoform delta2.7.11.10.469
1u54ACPActivated CDC42 kinase 1/0.468
2iw94SPCyclin-dependent kinase 22.7.11.220.468
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.468
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.468
4jboWPHAurora kinase A2.7.11.10.468
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.467
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.467
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.467
5e8xSTUTGF-beta receptor type-12.7.11.300.467
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.467
1xjdSTUProtein kinase C theta type2.7.11.130.466
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.466
2wouZZFTGF-beta receptor type-12.7.11.300.466
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.466
3poz03PEpidermal growth factor receptor2.7.10.10.466
4i22IREEpidermal growth factor receptor2.7.10.10.466
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.466
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.465
2iw84SPCyclin-dependent kinase 22.7.11.220.465
3rni21ZCyclin-dependent kinase 22.7.11.220.465
3sheI85MAP kinase-activated protein kinase 32.7.11.10.465
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.465
1m2pHNACasein kinase II subunit alpha2.7.11.10.464
1oirHDYCyclin-dependent kinase 22.7.11.220.464
1vyzN5BCyclin-dependent kinase 22.7.11.220.464
2h96893Mitogen-activated protein kinase 82.7.11.240.464
2y9qANPMitogen-activated protein kinase 12.7.11.240.464
3iok1P6Tyrosine-protein kinase JAK2/0.464
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.464
3zewSTUEphrin type-B receptor 42.7.10.10.464
4fki09KCyclin-dependent kinase 22.7.11.220.464
4uakADPSerine/threonine-protein kinase MRCK beta2.7.11.10.464
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.463
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
4eok4SPCyclin-dependent kinase 22.7.11.220.463
1xkkFMMEpidermal growth factor receptor2.7.10.10.462
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.462
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.462
2w05FRTCyclin-dependent kinase 22.7.11.220.462
2wtkANPSTE20-related kinase adapter protein alpha/0.462
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.462
4gmy0X5Tyrosine-protein kinase JAK2/0.462
4gu610NFocal adhesion kinase 12.7.10.20.462
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.461
3a60STURibosomal protein S6 kinase beta-12.7.11.10.461
3lfnA27Cyclin-dependent kinase 22.7.11.220.461
4a9hTVPBromodomain-containing protein 2/0.461
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4dgmAGICasein kinase II subunit alpha2.7.11.10.461
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4fmqANPMitogen-activated protein kinase 12.7.11.240.461
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.460
2yn8STUEphrin type-B receptor 42.7.10.10.460
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4f9b0SYCell division cycle 7-related protein kinase2.7.11.10.460
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.460
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.460
2b52D42Cyclin-dependent kinase 22.7.11.220.459
2csnCKICasein kinase I homolog 12.7.11.10.459
2uzeC95Cyclin-dependent kinase 22.7.11.220.459
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.459
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.459
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.459
4bcpT3CCyclin-dependent kinase 22.7.11.220.459
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.459
5auxKMPDeath-associated protein kinase 12.7.11.10.459
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.458
1wvxBD4Death-associated protein kinase 12.7.11.10.458
2btrU73Cyclin-dependent kinase 22.7.11.220.458
2pvlP55Casein kinase II subunit alpha2.7.11.10.458
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.458
1aq1STUCyclin-dependent kinase 22.7.11.220.457
1ir3ANPInsulin receptor2.7.10.10.457
1rw8580TGF-beta receptor type-12.7.11.300.457
2cchATPCyclin-dependent kinase 22.7.11.220.457
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2zjwREFCasein kinase II subunit alpha2.7.11.10.457
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.457
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.457
4ek610KCyclin-dependent kinase 22.7.11.220.457
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.457
4y93746Tyrosine-protein kinase/0.457
1bdrIM1Gag-Pol polyprotein3.4.23.160.456
1e9hINRCyclin-dependent kinase 22.7.11.220.456
1ykr628Cyclin-dependent kinase 22.7.11.220.456
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3le62BZCyclin-dependent kinase 22.7.11.220.456
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.456
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.456
4fv6E57Mitogen-activated protein kinase 12.7.11.240.456
4grb0XGCasein kinase II subunit alpha2.7.11.10.456
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.456
5e8ySTUTGF-beta receptor type-22.7.11.300.456
5e92ANPTGF-beta receptor type-22.7.11.300.456
2vtqLZACyclin-dependent kinase 22.7.11.220.455
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3roy22ZCyclin-dependent kinase 22.7.11.220.455
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.455
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.455
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.455
1bygSTUTyrosine-protein kinase CSK/0.454
2wotZZGTGF-beta receptor type-12.7.11.300.454
2x9fX9FEphrin type-B receptor 42.7.10.10.454
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.454
3c50ADPRhodopsin kinase/0.454
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.454
3lfqA28Cyclin-dependent kinase 22.7.11.220.454
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.454
4gk3L87Ephrin type-A receptor 32.7.10.10.454
4ix6ADPUncharacterized protein/0.454
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.453
3fklFKLMitogen-activated protein kinase 14/0.453
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.453
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.453
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fkv61KCyclin-dependent kinase 22.7.11.220.453
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.453
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.453
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.453
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.452
2btsU32Cyclin-dependent kinase 22.7.11.220.452
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.452
2i40BLZCyclin-dependent kinase 22.7.11.220.452
2uzlC94Cyclin-dependent kinase 22.7.11.220.452
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.452
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3gxlQIGTGF-beta receptor type-12.7.11.300.452
3rak03ZCyclin-dependent kinase 22.7.11.220.452
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.452
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.452
5cu6ATPCasein kinase II subunit alpha2.7.11.10.452
1z6tADPApoptotic protease-activating factor 1/0.451
2b7aIZATyrosine-protein kinase JAK2/0.451
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.451
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.451
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.451
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.451
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4erwSTUCyclin-dependent kinase 22.7.11.220.451
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4h3qANPMitogen-activated protein kinase 12.7.11.240.451
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
1y91CT9Cyclin-dependent kinase 22.7.11.220.450
1yvj4STTyrosine-protein kinase JAK32.7.10.20.450
2c5yMTWCyclin-dependent kinase 22.7.11.220.450
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.450
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.450
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.450
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.450
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.450
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.450
3r7eX88Cyclin-dependent kinase 22.7.11.220.450
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.450
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4k8aK8AFocal adhesion kinase 12.7.10.20.450
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.450
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.450
5auvAGIDeath-associated protein kinase 12.7.11.10.450
1bdlIM1Gag-Pol polyprotein3.4.23.160.449
2acxANPG protein-coupled receptor kinase 62.7.11.160.449
2d29FADAcyl-CoA dehydrogenase/0.449
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2izrBRKCasein kinase I isoform gamma-32.7.11.10.449
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.449
3iaeD7KBenzaldehyde lyase/0.449
3lltANPProtein serine/threonine kinase-1/0.449
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.449
4eoi1ROCyclin-dependent kinase 22.7.11.220.449
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.449
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4mgiCMPRap guanine nucleotide exchange factor 4/0.449
4nk92K5Fibroblast growth factor receptor 1/0.449
1oguST8Cyclin-dependent kinase 22.7.11.220.448
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.448
1ungALHCyclin-dependent-like kinase 52.7.11.10.448
2hckQUETyrosine-protein kinase HCK2.7.10.20.448
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.448
3bvb017Gag-Pol polyprotein3.4.23.160.448
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.448
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.448
3kf7L9GMitogen-activated protein kinase 14/0.448
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3rk708ZCyclin-dependent kinase 22.7.11.220.448
3s2pPMUCyclin-dependent kinase 22.7.11.220.448
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.448
4e6d0NUTyrosine-protein kinase JAK2/0.448
4fkj11KCyclin-dependent kinase 22.7.11.220.448
4fob0USALK tyrosine kinase receptor2.7.10.10.448
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.448
4nj32KDCyclin-dependent kinase 22.7.11.220.448
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.448
1e1xNW1Cyclin-dependent kinase 22.7.11.220.447
2iqgF2IBeta-secretase 13.4.23.460.447
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.447
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.447
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.447
3dds26BGlycogen phosphorylase, liver form2.4.1.10.447
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.447
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.447
4ez50RSCyclin-dependent kinase 62.7.11.220.447
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.447
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.447
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.447
4qmySTUSerine/threonine-protein kinase 242.7.11.10.447
4qnaX11Serine/threonine-protein kinase 242.7.11.10.447
1csnATPCasein kinase I homolog 12.7.11.10.446
2b55D31Cyclin-dependent kinase 22.7.11.220.446
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.446
2p5fSAHDiphthine synthase/0.446
2pvmP29Casein kinase II subunit alpha2.7.11.10.446
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.446
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.446
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.446
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.446
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.446
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.445
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.445
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.445
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.445
2f2uM77Rho-associated protein kinase 22.7.11.10.445
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2uzdC85Cyclin-dependent kinase 22.7.11.220.445
3clyACPFibroblast growth factor receptor 2/0.445
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.445
3ormAGSSerine/threonine protein kinase/0.445
3r9hZ67Cyclin-dependent kinase 22.7.11.220.445
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
1blzACVIsopenicillin N synthase1.21.3.10.444
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1h0w207Cyclin-dependent kinase 22.7.11.220.444
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1v0oINRCell division control protein 2 homolog2.7.11.220.444
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2izsBRQCasein kinase I isoform gamma-32.7.11.10.444
2izt23DCasein kinase I isoform gamma-32.7.11.10.444
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.444
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.444
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.444
3eyhIZATyrosine-protein kinase JAK1/0.444
3vf9477Tyrosine-protein kinase SYK2.7.10.20.444
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.444
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4eooATPCyclin-dependent kinase 22.7.11.220.444
4hge15VTyrosine-protein kinase JAK2/0.444
1ke6LS2Cyclin-dependent kinase 22.7.11.220.443
1merDMQGag-Pol polyprotein3.4.23.160.443
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2ev9NAPShikimate dehydrogenase (NADP(+))/0.443
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.443
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
3qaaG04Gag-Pol polyprotein3.4.23.160.443
3qwkX62Cyclin-dependent kinase 22.7.11.220.443
3zep1NXTyrosine-protein kinase JAK32.7.10.20.443
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.443
4bcmT7ZCyclin-dependent kinase 22.7.11.220.443
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.443
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.443
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4wsqKSAAP2-associated protein kinase 12.7.11.10.443
5aniES4Cyclin-dependent kinase 22.7.11.220.443
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.442
2of2547Tyrosine-protein kinase Lck2.7.10.20.442
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.442
2vtrLZBCyclin-dependent kinase 22.7.11.220.442
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.442
3r73X87Cyclin-dependent kinase 22.7.11.220.442
3vryB43Tyrosine-protein kinase HCK2.7.10.20.442
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
4bchT7ZCyclin-dependent kinase 92.7.11.220.442
4c61LMMTyrosine-protein kinase JAK2/0.442
4dbzNDPPutative ketoacyl reductase1.3.10.442
4f99ADPCell division cycle 7-related protein kinase2.7.11.10.442
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4hvg19QTyrosine-protein kinase JAK32.7.10.20.442
4qmpDKISerine/threonine-protein kinase 242.7.11.10.442
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1pkdUCNCyclin-dependent kinase 22.7.11.220.441
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.441
2cciATPCyclin-dependent kinase 22.7.11.220.441
2pmnK51Protein kinase 7/0.441
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.441
2y6fM9FIsopenicillin N synthase1.21.3.10.441
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.441
3a7hATPSerine/threonine-protein kinase 242.7.11.10.441
4fod0UVALK tyrosine kinase receptor2.7.10.10.441
4kb81QNCasein kinase I isoform delta2.7.11.10.441
5cnoANPEpidermal growth factor receptor2.7.10.10.441
1b6mPI6Gag-Pol polyprotein3.4.23.160.440
1xl2189Gag-Pol polyprotein3.4.23.160.440
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.440
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.440
3rvg17PTyrosine-protein kinase JAK2/0.440
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.440
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.440
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.440
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.440
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.440