sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3lmh | ADP | Myosin heavy chain kinase A | 2.7.11.7 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3lmh | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 1.000 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.628 | |
| 4zs4 | ATP | Myosin heavy chain kinase A | 2.7.11.7 | 0.615 | |
| 5e9e | ANP | Myosin heavy chain kinase A | 2.7.11.7 | 0.611 | |
| 4zme | ADN | Myosin heavy chain kinase A | 2.7.11.7 | 0.609 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.558 | |
| 1ia9 | ANP | Transient receptor potential cation channel subfamily M member 7 | 2.7.11.1 | 0.532 | |
| 3lmi | ATP | Myosin heavy chain kinase A | 2.7.11.7 | 0.509 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.507 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.498 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.496 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.493 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.490 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.489 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.488 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.487 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.486 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.480 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.479 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.479 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.479 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.478 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.478 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.477 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.477 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.474 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.474 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.474 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.473 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.472 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.472 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.472 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.471 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.471 | |
| 2yog | 74X | Thymidylate kinase | / | 0.470 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.469 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.468 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.467 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.466 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.466 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.466 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.465 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.464 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.463 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.462 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.461 | |
| 3v49 | PK0 | Androgen receptor | / | 0.461 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.460 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.460 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.460 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.460 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.460 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.459 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.459 | |
| 2z1x | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.459 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.459 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.458 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.458 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.457 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.457 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.456 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.456 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.456 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.455 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.454 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.454 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.453 | |
| 1s4e | ADP | Galactokinase | / | 0.453 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.453 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.453 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.453 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.453 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.452 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.452 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.452 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.452 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
| 3zp4 | TSA | Chorismate mutase AroH | 5.4.99.5 | 0.452 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.452 | |
| 1syn | F89 | Thymidylate synthase | / | 0.451 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.451 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.451 | |
| 4gd9 | BTN | Streptavidin | / | 0.451 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2ejz | SAH | Diphthine synthase | / | 0.450 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.450 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.450 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.449 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.449 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.449 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.449 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.449 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.449 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.449 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.449 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.449 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.449 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.449 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.449 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.448 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.448 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.448 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.448 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.448 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.448 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.447 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.447 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.447 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.447 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.447 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.446 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.446 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.446 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.446 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.446 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.445 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3up3 | XCA | aceDAF-12 | / | 0.445 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.445 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.445 | |
| 4zas | TYD | CalS13 | / | 0.445 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.444 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 1c1c | 612 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.443 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.443 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.443 | |
| 2j0s | ANP | Eukaryotic initiation factor 4A-III | 3.6.4.13 | 0.443 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.443 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.443 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.443 | |
| 4eyb | 0WO | Metallo-beta-lactamase type 2 | / | 0.443 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.443 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.443 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.442 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.442 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.442 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.442 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.442 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3arp | DEQ | Chitinase A | / | 0.442 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.442 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4fgj | 1PQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.442 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.441 | |
| 2y03 | 5FW | Beta-1 adrenergic receptor | / | 0.441 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 3u3o | 3QV | Sulfotransferase 1A1 | 2.8.2.1 | 0.441 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.441 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.441 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.440 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.440 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.440 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.440 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.440 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.440 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.440 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.440 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4yfy | 0FX | VioF | / | 0.440 |