sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.859 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.703 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.677 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.666 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.660 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.657 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.652 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.651 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.650 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.645 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.638 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.638 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.638 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.637 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.636 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.635 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.634 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.633 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.633 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.632 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.626 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.621 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.619 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.619 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.618 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.612 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.610 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.608 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.608 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.605 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.603 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.601 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.601 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.599 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.599 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.597 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.593 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.591 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.588 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.583 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.582 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.576 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.574 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.571 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.565 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.564 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.564 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.561 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.541 | |
| 2pfh | NDP | Aldose reductase | 1.1.1.21 | 0.539 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.537 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.526 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.513 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.510 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.506 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.501 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.500 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.499 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.498 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.497 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.494 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.492 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.489 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.489 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.489 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.488 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.487 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.486 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.485 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.485 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.484 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.483 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.482 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.481 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.479 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.476 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.475 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.475 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.475 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.474 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.474 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.473 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.473 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.472 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.471 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.471 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.471 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.471 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.471 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.470 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.469 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.469 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.469 | |
| 2qry | TPS | Thiamine-binding periplasmic protein | / | 0.469 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.469 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.469 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.469 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.469 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.469 | |
| 1e6z | NGO | Chitinase | / | 0.468 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.468 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.468 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.467 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.467 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.465 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.464 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.464 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.463 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.462 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.462 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.462 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.462 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.462 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.461 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 2hzq | STR | Apolipoprotein D | / | 0.461 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.461 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.461 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.461 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 4kmz | FOL | Folate receptor beta | / | 0.461 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.461 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.460 | |
| 4phl | PIL | Phosphodiesterase | / | 0.460 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.460 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.459 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.459 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.458 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.458 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.458 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.458 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.458 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.457 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.457 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.456 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.456 | |
| 1fml | RTL | Retinol dehydratase | / | 0.456 | |
| 1s36 | CEI | Obelin | / | 0.456 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.456 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.456 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.456 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.456 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.456 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.456 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.455 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.454 | |
| 1qvt | PRL | HTH-type transcriptional regulator QacR | / | 0.454 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.454 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.454 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.454 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.454 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.454 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.454 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.454 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.454 | |
| 1ah4 | NAP | Aldose reductase | 1.1.1.21 | 0.453 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1rxj | BNI | Streptavidin | / | 0.453 | |
| 1s07 | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.453 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.453 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.453 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.453 | |
| 5ero | 210 | Fusicoccadiene synthase | 2.5.1.29 | 0.453 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.452 | |
| 1u08 | PLP | Methionine aminotransferase | / | 0.452 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.452 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.452 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.452 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.451 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.451 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.451 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.450 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.450 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.450 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 3p9t | TCL | Repressor | / | 0.450 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4ho6 | UPG | Glucose-1-phosphate thymidylyltransferase | / | 0.450 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.450 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.450 | |
| 2vut | NAD | Nitrogen metabolite repression protein nmrA | / | 0.449 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.449 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.449 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 1e2l | TMC | Thymidine kinase | / | 0.448 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.448 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2qjp | ANJ | Cytochrome b | / | 0.448 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.448 | |
| 3ufy | NPX | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.448 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.448 | |
| 4rel | KMP | Glycosyltransferase | / | 0.448 | |
| 4yfy | 0FX | VioF | / | 0.448 | |
| 1lke | DOG | Bilin-binding protein | / | 0.447 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.447 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.447 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2vq3 | NAP | Metalloreductase STEAP3 | / | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.447 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4x3u | SVR | Chromobox protein homolog 7 | / | 0.447 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.447 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.446 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.446 | |
| 4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.446 | |
| 1dtp | APU | Diphtheria toxin | / | 0.445 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.445 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.445 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.445 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.445 | |
| 1az1 | ALR | Aldose reductase | 1.1.1.21 | 0.444 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.444 | |
| 1jf2 | CZH | Obelin | / | 0.444 | |
| 2gh6 | CF3 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.444 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.444 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.444 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.444 | |
| 4hcy | 0YN | Transketolase | / | 0.444 | |
| 4j7h | TRH | PCZA361.3 | / | 0.444 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.444 | |
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 0.443 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.443 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.443 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.443 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2r1n | EPL | Phosphotriesterase | / | 0.443 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3cui | X4S | Exoglucanase/xylanase | 3.2.1.91 | 0.443 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.443 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3dz6 | M8E | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.443 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.443 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.443 | |
| 1ads | NAP | Aldose reductase | 1.1.1.21 | 0.442 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1w1p | GIO | Chitinase | / | 0.442 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.442 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.442 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.442 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.442 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.442 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4e32 | DWN | Methyltransferase | / | 0.442 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 4mrx | CZH | Obelin | / | 0.442 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.441 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.441 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.441 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3fvu | IAC | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.441 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4e2y | JHZ | Methyltransferase | / | 0.441 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 4iae | 1DX | Alr2278 protein | / | 0.441 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.441 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.440 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.440 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.440 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.440 | |
| 3bmq | AX5 | Pteridine reductase | / | 0.440 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.440 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.440 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.440 | |
| 4kxj | P34 | Nucleoprotein | / | 0.440 |