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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ap0ADPKinesin-like protein KIF11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4ap0ADPKinesin-like protein KIF11/1.000
4a1zADPKinesin-like protein KIF11/0.517
1ii6ADPKinesin-like protein KIF11/0.515
2gm1ADPKinesin-like protein KIF11/0.507
3hqdANPKinesin-like protein KIF11/0.507
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.506
2ji6ADPOxalyl-CoA decarboxylase4.1.1.80.499
2x2rADPKinesin-like protein KIF11/0.499
3gcq1BUMitogen-activated protein kinase 14/0.497
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.494
1rf9DBRCamphor 5-monooxygenase1.14.15.10.493
2zb1GK4Mitogen-activated protein kinase 14/0.492
3cobADPKinesin heavy chain-like protein/0.492
3fkoFKOMitogen-activated protein kinase 14/0.492
3p6nDSOCamphor 5-monooxygenase1.14.15.10.491
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.490
3s7a684Dihydrofolate reductase1.5.1.30.490
2ftoCB3Thymidylate synthase/0.489
2qc8ADPGlutamine synthetase6.3.1.20.489
3iw8HIZMitogen-activated protein kinase 14/0.489
1xlsREARetinoic acid receptor RXR-alpha/0.487
2y65ADPKinesin heavy chain/0.486
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.485
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.484
5g53NECAdenosine receptor A2a/0.484
1pd9CO4Dihydrofolate reductase1.5.1.30.482
3p6oETGCamphor 5-monooxygenase1.14.15.10.482
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.482
1hb1OCVIsopenicillin N synthase1.21.3.10.481
1jomFFODihydrofolate reductase1.5.1.30.480
3k3bADPKinesin-like protein KIF11/0.480
3p6mDSOCamphor 5-monooxygenase1.14.15.10.480
4a51ADPKinesin-like protein KIF11/0.480
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.478
1xiuREARetinoic acid receptor RXR/0.478
4knzCB3Thymidylate synthase/0.478
4pl9ADPEthylene receptor 1/0.478
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.477
1x8b824Wee1-like protein kinase2.7.10.20.476
1yrsADPKinesin-like protein KIF11/0.476
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.476
2ydoADNAdenosine receptor A2a/0.476
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.476
1fd0254Retinoic acid receptor gamma/0.475
1mznBM6Retinoic acid receptor RXR-alpha/0.475
4a28ADPKinesin-like protein KIF11/0.475
4bb3KKAIsopenicillin N synthase1.21.3.10.475
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.475
1re9DSOCamphor 5-monooxygenase1.14.15.10.474
3a1l2CCCytochrome P450/0.474
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.474
2pulACPMethylthioribose kinase2.7.1.1000.473
3adaNADSubunit alpha of sarocosine oxidase/0.473
3d7zGK5Mitogen-activated protein kinase 14/0.473
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.472
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.471
2lbdREARetinoic acid receptor gamma/0.471
2q2yADPKinesin-like protein KIF11/0.471
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.471
1f9aATPNicotinamide-nucleotide adenylyltransferase/0.470
3bqdDAYGlucocorticoid receptor/0.470
4el9AFERibosomal protein S6 kinase alpha-32.7.11.10.470
4zcaADPKinesin-like protein KIF11/0.470
2vcwZZAHematopoietic prostaglandin D synthase/0.469
3bgxMEFThymidylate synthase/0.469
3hv3R49Mitogen-activated protein kinase 14/0.469
3nx4NAPPutative oxidoreductase/0.469
1blzACVIsopenicillin N synthase1.21.3.10.468
1hb3SCVIsopenicillin N synthase1.21.3.10.468
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.468
3w2cN15Aurora kinase A2.7.11.10.468
3itzP66Mitogen-activated protein kinase 14/0.467
4iqqD16Thymidylate synthase/0.467
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
4xe606UDihydrofolate reductase1.5.1.30.467
1disBDMDihydrofolate reductase1.5.1.30.466
1iahADPTransient receptor potential cation channel subfamily M member 72.7.11.10.466
1mvsDTMDihydrofolate reductase1.5.1.30.466
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.466
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.466
2wpxACOOrf14/0.466
3p6pA6BCamphor 5-monooxygenase1.14.15.10.466
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.466
1dhjMTXDihydrofolate reductase1.5.1.30.465
3e5aVX6Aurora kinase A2.7.11.10.465
3gc8B45Mitogen-activated protein kinase 112.7.11.240.465
3htjETEbrA repressor/0.465
3up0D7SaceDAF-12/0.465
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.464
2ji7ADPOxalyl-CoA decarboxylase4.1.1.80.464
3falREARetinoic acid receptor RXR-alpha/0.464
3rinI2OMitogen-activated protein kinase 14/0.464
4gevCB3Thymidylate synthase/0.464
1bzfTMQDihydrofolate reductase1.5.1.30.463
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.463
1w06W05Isopenicillin N synthase1.21.3.10.463
1zdwFLVPrenyltransferase/0.463
2w6oOA3Biotin carboxylase6.3.4.140.463
3a4pDFQHepatocyte growth factor receptor2.7.10.10.463
3iw5DF3Mitogen-activated protein kinase 14/0.463
4isk1JYThymidylate synthase/0.463
4x5jFOLDihydrofolate reductase1.5.1.30.463
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.463
1fcx184Retinoic acid receptor gamma/0.462
1oc1ASVIsopenicillin N synthase1.21.3.10.462
1p16GTPmRNA-capping enzyme subunit alpha2.7.7.500.462
3p9tTCLRepressor/0.462
3tdaPN0Cytochrome P450 2D6/0.462
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.462
4elb34SDihydrofolate reductase/0.462
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.462
4kf1HT5Aryldialkylphosphatase3.1.8.10.462
1qiqACCIsopenicillin N synthase1.21.3.10.461
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.461
1s3uTQDDihydrofolate reductase1.5.1.30.461
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.461
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.461
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.461
3fl4FL4Mitogen-activated protein kinase 14/0.461
4jbtASDCytochrome P450 monooxygenase/0.461
4o4eATPKinase/0.461
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.461
3uzcT4EAdenosine receptor A2a/0.461
2dhfDZFDihydrofolate reductase1.5.1.30.460
2gfsPQBMitogen-activated protein kinase 14/0.460
3abaFLICytochrome P450/0.460
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.460
1kzjCB3Thymidylate synthase/0.459
1n6mADPProtein claret segregational/0.459
1zzlTZYMitogen-activated protein kinase 14/0.459
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.459
2o7pNAPRiboflavin biosynthesis protein RibD/0.459
2z3uCRRCytochrome P450/0.459
3hziATPSerine/threonine-protein kinase toxin HipA/0.459
3m7rVDXVitamin D3 receptor/0.459
3n33AESBeta-peptidyl aminopeptidase BapA/0.459
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.459
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.459
5hi6MTXDihydrofolate reductase/0.459
1db1VDXVitamin D3 receptor/0.458
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.458
1rd4L08Integrin alpha-L/0.458
2hasC3OVitamin D3 receptor/0.458
2idkC2FGlycine N-methyltransferase2.1.1.200.458
2nsd4PIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.458
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.458
4ia2BIVVitamin D3 receptor A/0.458
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.458
5ifyUMPGlucose-1-phosphate thymidylyltransferase/0.458
1s3vTQDDihydrofolate reductase1.5.1.30.457
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.457
2qk8MTXDihydrofolate reductase/0.457
3gc9B45Mitogen-activated protein kinase 112.7.11.240.457
3lfcZ86Mitogen-activated protein kinase 14/0.457
4aseAV9Vascular endothelial growth factor receptor 22.7.10.10.457
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.457
5bp9SAHPutative methyltransferase protein/0.457
1ib1COTSerotonin N-acetyltransferase/0.456
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.456
1uy9PU6Heat shock protein HSP 90-alpha/0.456
2aazCB3Thymidylate synthase2.1.1.450.456
3f82353Hepatocyte growth factor receptor2.7.10.10.456
3l9hADPKinesin-like protein KIF11/0.456
3zoiM2WIsopenicillin N synthase1.21.3.10.456
4d4sBI9Focal adhesion kinase 12.7.10.20.456
4foxD16Thymidylate synthase ThyA/0.456
4xr9TMPCalS8/0.456
4ybnFADFlavin-nucleotide-binding protein/0.456
5k2cZMAAdenosine receptor A2a/0.456
3reyXACAdenosine receptor A2a/0.456
1jutLYDThymidylate synthase/0.455
1trgCB3Thymidylate synthase/0.455
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.455
2hcdBIVVitamin D3 receptor A/0.455
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
2pg2ADPKinesin-like protein KIF11/0.455
3gcpSB2Mitogen-activated protein kinase 14/0.455
3ol5SAWCamphor 5-monooxygenase1.14.15.10.455
4eyjN61Mitogen-activated protein kinase 132.7.11.240.455
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.455
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.455
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
5dozNDPJamJ/0.455
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.454
1jtuLYBThymidylate synthase/0.454
1kceCB3Thymidylate synthase/0.454
1rc4DDFDihydrofolate reductase1.5.1.30.454
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.454
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.454
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.454
2vbpVB1Isopenicillin N synthase1.21.3.10.454
3ds6A17Mitogen-activated protein kinase 14/0.454
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.454
3zkuHCVIsopenicillin N synthase1.21.3.10.454
4e37NDPCatalase1.11.1.60.454
4ej7ATPAminoglycoside 3'-phosphotransferase AphA1-IAB/0.454
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.454
4nh82LCHeat shock protein HSP 90-alpha/0.454
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
5kf9ACOPredicted acetyltransferase/0.454
3qakUKAAdenosine receptor A2a/0.454
1f4gTP4Thymidylate synthase/0.453
1ie8KH1Vitamin D3 receptor/0.453
1qjfACSIsopenicillin N synthase1.21.3.10.453
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.453
2y6fM9FIsopenicillin N synthase1.21.3.10.453
3cr7PPSAdenylyl-sulfate kinase2.7.1.250.453
3eigMTXDihydrofolate reductase1.5.1.30.453
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.453
3t9i3T9Serine/threonine-protein kinase pim-12.7.11.10.453
3w0aDS5Vitamin D3 receptor/0.453
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.453
4elb34RDihydrofolate reductase/0.453
4elg52JDihydrofolate reductase/0.453
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.453
4ia1BIVVitamin D3 receptor A/0.453
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.453
4l5b1UXDeoxycytidine kinase2.7.1.740.453
1diuBDMDihydrofolate reductase1.5.1.30.452
1q4xG24Thyroid hormone receptor beta/0.452
1rdtL79Retinoic acid receptor RXR-alpha/0.452
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.452
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.452
2h42VIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.452
3q44D50M1 family aminopeptidase3.4.110.452
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.452
4k9yK9YFocal adhesion kinase 12.7.10.20.452
3rfmCFFAdenosine receptor A2a/0.452
1cqp803Integrin alpha-L/0.451
1jtqLY3Thymidylate synthase/0.451
1re0AFBADP-ribosylation factor 1/0.451
1re0AFBARF guanine-nucleotide exchange factor 1/0.451
1tdrMTXDihydrofolate reductase1.5.1.30.451
2hziJINTyrosine-protein kinase ABL12.7.10.20.451
2jibADPOxalyl-CoA decarboxylase4.1.1.80.451
2p1t3TNRetinoic acid receptor RXR-alpha/0.451
3bhlTHGThymidylate synthase/0.451
3p3zP3ZPutative cytochrome P450/0.451
3te4ACODopamine N-acetyltransferase/0.451
3zsgT75Mitogen-activated protein kinase 14/0.451
4b8mVX6Aurora kinase B-A2.7.11.10.451
4c8b0LIReceptor-interacting serine/threonine-protein kinase 22.7.11.10.451
4fnyI3KALK tyrosine kinase receptor2.7.10.10.451
4iv21GREstrogen receptor/0.451
4ixd1HVIntegrin alpha-L/0.451
4ku5DCC3-oxoacyl-[ACP] synthase III/0.451
5kgpACOPredicted acetyltransferase/0.451
8catNDPCatalase1.11.1.60.451
5uviZMAAdenosine receptor A2a/0.451
1al7HSTPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.450
1cd2FOLDihydrofolate reductase1.5.1.30.450
1ci7CB3Thymidylate synthase2.1.1.450.450
2hb8MVDVitamin D3 receptor/0.450
2j8zNAPQuinone oxidoreductase PIG310.450
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.450
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.450
2ykcYKCHeat shock protein HSP 90-alpha/0.450
3datMTXDihydrofolate reductase/0.450
3drcMTXDihydrofolate reductase1.5.1.30.450
3fl8RARDihydrofolate reductase/0.450
3tk3CPZCytochrome P450 2B41.14.14.10.450
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.450
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.450
4fqsLYAThymidylate synthase ThyA/0.450
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
1axwMTXThymidylate synthase/0.449
1exa394Retinoic acid receptor gamma/0.449
1ie9VDXVitamin D3 receptor/0.449
1ly3COGDihydrofolate reductase1.5.1.30.449
1nceCB3Thymidylate synthase/0.449
1wxyFRKAdenosine deaminase3.5.4.40.449
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.449
2pupADPMethylthioribose kinase2.7.1.1000.449
2tscCB3Thymidylate synthase/0.449
2zb8IMNProstaglandin reductase 21.3.1.480.449
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3e92G6AMitogen-activated protein kinase 14/0.449
3kqjUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.449
4eqgA5AHistidine triad nucleotide-binding protein 130.449
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4n9iPCGCatabolite expression activator/0.449
4q15HFGProline--tRNA ligase6.1.1.150.449
4ruoBIVVitamin D3 receptor A/0.449
1jujLYAThymidylate synthase2.1.1.450.448
1rg7MTXDihydrofolate reductase1.5.1.30.448
1txtCAAHMG-CoA synthase/0.448
2aibERGBeta-elicitin cinnamomin/0.448
2bbqPFGThymidylate synthase/0.448
2c31ADPOxalyl-CoA decarboxylase4.1.1.80.448
2pg0FADAcyl-CoA dehydrogenase/0.448
2qg2A91Heat shock protein HSP 90-alpha/0.448
2v59LZKBiotin carboxylase6.3.4.140.448
3cp9C19Vascular endothelial growth factor receptor 22.7.10.10.448
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.448
4e5yNDPGDP-L-fucose synthase1.1.1.2710.448
4ea2RWZDehydrosqualene synthase/0.448
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4ia3BIVVitamin D3 receptor A/0.448
4mfb29TGag-Pol polyprotein2.7.7.490.448
5ab7MLCNonspecific lipid-transfer protein, putative/0.448
1qvnFRIInterleukin-2/0.447
1y6qTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.447
1yw2PGJMitogen-activated protein kinase 14/0.447
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2b9wFADPutative aminooxidase/0.447
2bakAQZMitogen-activated protein kinase 14/0.447
2bjsACVIsopenicillin N synthase1.21.3.10.447
2fwzH71Heat shock protein HSP 90-alpha/0.447
2imkGTXAGAP009194-PA/0.447
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
2vbdV10Isopenicillin N synthase1.21.3.10.447
2vn0TDZCytochrome P450 2C8/0.447
2wleCOAPolysialic acid O-acetyltransferase/0.447
2ykbYKBHeat shock protein HSP 90-alpha/0.447
3iupNDPPossible NADH oxidoreductase/0.447
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3ormAGSSerine/threonine protein kinase/0.447
3thrC2FGlycine N-methyltransferase2.1.1.200.447
4a9yAQZMitogen-activated protein kinase 14/0.447
4burNADApoptosis-inducing factor 1, mitochondrial1.1.10.447
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.447
4ia7BIVVitamin D3 receptor A/0.447
4lsl1YQGag-Pol polyprotein2.7.7.490.447
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.447
1hskFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.446
1uydPU8Heat shock protein HSP 90-alpha/0.446
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
2w5aADPSerine/threonine-protein kinase Nek22.7.11.10.446
2y60M8FIsopenicillin N synthase1.21.3.10.446
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.446
3ctj320Hepatocyte growth factor receptor2.7.10.10.446
3hub469Mitogen-activated protein kinase 14/0.446
3llaACPMyosin heavy chain kinase A2.7.11.70.446
3qarQARPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.446
3t2kFADSulfide-quinone reductase/0.446
3vt7VDXVitamin D3 receptor/0.446
4dscA8SAbscisic acid receptor PYL3/0.446
4gg70J8Hepatocyte growth factor receptor2.7.10.10.446
4iteTEYVitamin D3 receptor/0.446
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.446
4kak06UDihydrofolate reductase1.5.1.30.446
4nb6444Nuclear receptor ROR-gamma/0.446
4r20AERCytochrome P450 family 17 polypeptide 2/0.446
4rh10TTSpore photoproduct lyase/0.446
1ygjRMCPyridoxal kinase2.7.1.350.445
2cahNDPCatalase1.11.1.60.445
2ewaSB2Mitogen-activated protein kinase 14/0.445
2iviACWIsopenicillin N synthase1.21.3.10.445
2og81N8Tyrosine-protein kinase Lck2.7.10.20.445
2ydwWSHBromodomain-containing protein 2/0.445
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
3cth319Hepatocyte growth factor receptor2.7.10.10.445
3qm4PN0Cytochrome P450 2D6/0.445
3qwiCUE17beta-hydroxysteroid dehydrogenase/0.445
3slkNDPPolyketide synthase extender module 2/0.445
4ea0651Dehydrosqualene synthase/0.445
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.445
4hneADPPhosphatidylinositol 4-kinase type 2-alpha/0.445
4l8u9AZSerum albumin/0.445
4m63ATPActin-5C/0.445
4mfpCOAUncharacterized protein/0.445
5itzLOCTubulin beta-2B chain/0.445
1aiqCB3Thymidylate synthase/0.444
1f4fTP3Thymidylate synthase/0.444
1gjrNAPFerredoxin--NADP reductase1.18.1.20.444
1h35R01Squalene--hopene cyclase4.2.1.1290.444
1rd7FOLDihydrofolate reductase1.5.1.30.444
2in6839Wee1-like protein kinase2.7.10.20.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
2jblSMAReaction center protein L chain/0.444
2p1u4TNRetinoic acid receptor RXR-alpha/0.444
2qocANPEphrin type-A receptor 32.7.10.10.444
2w6nOA2Biotin carboxylase6.3.4.140.444
2zl9VDAVitamin D3 receptor/0.444
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.444
3jynNDPQuinone oxidoreductase/0.444
3q0vLL4HTH-type transcriptional regulator EthR/0.444
3tqhNDPQuinone oxidoreductase/0.444
3zsh469Mitogen-activated protein kinase 14/0.444
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4af3VX6Aurora kinase B2.7.11.10.444
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4iah1DXAlr2278 protein/0.444
1dhfFOLDihydrofolate reductase1.5.1.30.443
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.443
1nq7ARLNuclear receptor ROR-beta/0.443
1uymPU3Heat shock protein HSP 90-beta/0.443
1uzwCDHIsopenicillin N synthase1.21.3.10.443
1v8kANPKinesin-like protein KIF2C/0.443
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2w5bAGSSerine/threonine-protein kinase Nek22.7.11.10.443
2z4sADPChromosomal replication initiator protein DnaA/0.443
3bhrTHGThymidylate synthase/0.443
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3i0pNADMalate dehydrogenase, putative/0.443
3ibdCPZCytochrome P450 2B61.14.130.443
3lmhADPMyosin heavy chain kinase A2.7.11.70.443
3mdvCL6Cholesterol 24-hydroxylase/0.443
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.443
3rix923Luciferin 4-monooxygenase1.13.12.70.443
3stxBKAMethylketone synthase I/0.443
3tubFPUTyrosine-protein kinase SYK2.7.10.20.443
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.443
4eevL1XHepatocyte growth factor receptor2.7.10.10.443
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.443
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.443
4jx1CAHCamphor 5-monooxygenase1.14.15.10.443
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4u9vACON-alpha-acetyltransferase 402.3.10.443
5iqeGNPBifunctional AAC/APH2.3.10.443
1draMTXDihydrofolate reductase1.5.1.30.442
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.442
1jlcFTCGag-Pol polyprotein2.7.7.490.442
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.442
1o1vTCHGastrotropin/0.442
1s9dAFBCytohesin-2/0.442
1s9dAFBADP-ribosylation factor 1/0.442
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
1suoCPZCytochrome P450 2B41.14.14.10.442
1tduCB3Thymidylate synthase/0.442
1u1d181Uridine phosphorylase2.4.2.30.442
1xdkREARetinoic acid receptor beta/0.442
1zprCB3Thymidylate synthase/0.442
2x7hPFNProstaglandin reductase 310.442
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.442
3dtwA96Vascular endothelial growth factor receptor 22.7.10.10.442
3irxUDRGag-Pol polyprotein2.7.7.490.442
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.442
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4c2wANPAurora kinase B-A2.7.11.10.442
4ffmADPUncharacterized protein/0.442
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.442
4iaq2GM5-hydroxytryptamine receptor 1B/0.442
4ma628EAra h 8 allergen/0.442
1l8qADPChromosomal replication initiator protein DnaA/0.441
1ra3NAPDihydrofolate reductase1.5.1.30.441
1u3s797Estrogen receptor beta/0.441
1w78PD8Dihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.441
2hb7O1CVitamin D3 receptor/0.441
2hm9TRRDihydrofolate reductase1.5.1.30.441
2wmeNAPNAD/NADP-dependent betaine aldehyde dehydrogenase/0.441
3s41S41Glucokinase2.7.1.20.441
3stv3HOMethylketone synthase I/0.441
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.441
3vw8DF6Hepatocyte growth factor receptor2.7.10.10.441
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.441
4dbs0HVAldo-keto reductase family 1 member C3/0.441
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.441
4ktl1CQCytochrome P450/0.441
4oztP1AEcdysone receptor, putative/0.441
4ykfNAIAlkyl hydroperoxide reductase subunit F1.8.10.441
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1kl2FONSerine hydroxymethyltransferase/0.440
1kquBR4Phospholipase A2, membrane associated/0.440
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.440
1w83L11Mitogen-activated protein kinase 14/0.440
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.440
2np7NEAModification methylase TaqI2.1.1.720.440
2zpaADPtRNA(Met) cytidine acetyltransferase TmcA/0.440
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3p99LNPLanosterol 14-alpha-demethylase/0.440
3up3XCAaceDAF-12/0.440
3w0yDS4Vitamin D3 receptor/0.440
4dhyS41Glucokinase2.7.1.20.440
4eftEFTHeat shock protein HSP 90-alpha/0.440
4ele31IDihydrofolate reductase/0.440
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.440
4ixc1JDGlucokinase2.7.1.20.440
4jwpACOGCN5-related N-acetyltransferase/0.440
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.440
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.440
4zhxC1V5'-AMP-activated protein kinase catalytic subunit alpha-2/0.440
4zhxC1V5'-AMP-activated protein kinase subunit beta-1/0.440
5bt42LOBromodomain-containing protein 4/0.440
5i2fBS5Histidine triad nucleotide-binding protein 130.440
3uzaT4GAdenosine receptor A2a/0.440