sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3wtk | TH4 | Acetylcholine-binding protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3wtk | TH4 | Acetylcholine-binding protein | / | 1.000 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.596 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.580 | |
| 3wti | CT4 | Acetylcholine-binding protein | / | 0.528 | |
| 4alx | IZN | Acetylcholine-binding protein | / | 0.506 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.503 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.503 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.487 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.484 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.479 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.476 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.475 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.473 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.471 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.471 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.470 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.470 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.470 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.469 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.468 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.468 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.468 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.468 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.466 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 3zdh | XRS | Acetylcholine-binding protein | / | 0.466 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.466 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.465 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.465 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.465 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.465 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.465 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.465 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.465 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.464 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.464 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.464 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.464 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.463 | |
| 1fml | RTL | Retinol dehydratase | / | 0.463 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.463 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.463 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.463 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.463 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.462 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.462 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.462 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.461 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.461 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.461 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.461 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.461 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.461 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.461 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.460 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.460 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.460 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.460 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.459 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.459 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.458 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.457 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.457 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.457 | |
| 3v2u | ATP | Protein GAL3 | / | 0.457 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.457 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.456 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.456 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.456 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.456 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.455 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.455 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.455 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.455 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.455 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.454 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.454 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.454 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.454 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.454 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.454 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.453 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.453 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.453 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.453 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.453 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.453 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.452 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.452 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.452 | |
| 3tw6 | ADP | Pyruvate carboxylase | / | 0.452 | |
| 4l9k | EHF | Serum albumin | / | 0.452 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.451 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.451 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3mla | JJZ | Probable nicotinate-nucleotide adenylyltransferase | / | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.451 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.451 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.450 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.450 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.450 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.450 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.450 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.449 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.449 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.449 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.449 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.449 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.449 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.448 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.448 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.448 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.448 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.448 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.448 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.448 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2xvv | 9DN | Serum albumin | / | 0.448 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.448 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.448 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4iji | 99T | Glutathione S-transferase-like protein YibF | / | 0.448 | |
| 4lb2 | DM5 | Serum albumin | / | 0.448 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.447 | |
| 1r2j | FAD | FkbI | / | 0.447 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.447 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.447 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.446 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.446 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.446 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.446 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.446 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.446 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.446 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.446 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.445 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.445 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.445 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.445 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.445 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.445 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.444 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.444 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.444 | |
| 2r9v | ATP | ATP synthase subunit alpha | / | 0.444 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.444 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.444 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.444 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.443 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.443 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.443 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.443 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.443 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.443 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.443 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 5dp2 | NAP | CurF | / | 0.443 | |
| 1eio | GCH | Gastrotropin | / | 0.442 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.442 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.442 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.442 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3bhl | THG | Thymidylate synthase | / | 0.442 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.442 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.442 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.442 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.442 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.442 | |
| 5ios | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.442 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.441 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.441 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.441 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.441 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 4h6p | FMN | Chromate reductase | / | 0.441 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1axw | MTX | Thymidylate synthase | / | 0.440 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.440 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.440 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.440 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 2vax | CSC | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.440 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.440 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.440 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 3reo | SAH | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.440 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.440 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 |