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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vs7KS1Tyrosine-protein kinase HCK2.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3vs7KS1Tyrosine-protein kinase HCK2.7.10.21.000
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.603
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.601
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.588
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.587
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.585
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.583
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.583
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.581
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.580
3vs3VSETyrosine-protein kinase HCK2.7.10.20.576
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.571
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.568
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.565
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.563
1xkkFMMEpidermal growth factor receptor2.7.10.10.562
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.561
3vs1VSATyrosine-protein kinase HCK2.7.10.20.557
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.554
3vryB43Tyrosine-protein kinase HCK2.7.10.20.552
3w33W19Epidermal growth factor receptor2.7.10.10.552
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.551
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.545
4id71G0Activated CDC42 kinase 1/0.544
4nka2K7Fibroblast growth factor receptor 1/0.544
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.543
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.543
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.542
4i22IREEpidermal growth factor receptor2.7.10.10.537
4yuqKS1Calmodulin-like domain protein kinase/0.536
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.531
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.530
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.530
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.530
3zewSTUEphrin type-B receptor 42.7.10.10.529
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.528
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.525
4jq8KJ8Epidermal growth factor receptor2.7.10.10.525
1bygSTUTyrosine-protein kinase CSK/0.522
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.522
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.522
2of4979Tyrosine-protein kinase Lck2.7.10.20.520
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.519
2of2547Tyrosine-protein kinase Lck2.7.10.20.519
3poz03PEpidermal growth factor receptor2.7.10.10.519
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.519
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.517
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.516
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.516
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.516
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.515
2hk51BMTyrosine-protein kinase HCK2.7.10.20.514
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.514
1u54ACPActivated CDC42 kinase 1/0.513
2itnANPEpidermal growth factor receptor2.7.10.10.513
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.513
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.512
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.511
4gmy0X5Tyrosine-protein kinase JAK2/0.511
4riyADPEpidermal growth factor receptor2.7.10.10.511
2itqITQEpidermal growth factor receptor2.7.10.10.509
4gk2L66Ephrin type-A receptor 32.7.10.10.509
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.507
4fob0USALK tyrosine kinase receptor2.7.10.10.507
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.507
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.506
3w32W32Epidermal growth factor receptor2.7.10.10.506
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.506
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.506
4hjoAQ4Epidermal growth factor receptor2.7.10.10.506
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.505
3r9dX6BCyclin-dependent kinase 22.7.11.220.504
4gk4L90Ephrin type-A receptor 32.7.10.10.504
4hvh19RTyrosine-protein kinase JAK32.7.10.20.503
4jq7KJQEpidermal growth factor receptor2.7.10.10.503
4wkqIREEpidermal growth factor receptor2.7.10.10.503
1m17AQ4Epidermal growth factor receptor2.7.10.10.502
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.502
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.502
4f640S8Fibroblast growth factor receptor 1/0.502
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.502
3uvqFS8Mitogen-activated protein kinase 14/0.501
4nks2M2Fibroblast growth factor receptor 1/0.501
5e8xSTUTGF-beta receptor type-12.7.11.300.501
3js2VM1Fibroblast growth factor receptor 1/0.500
4ic7ANPMitogen-activated protein kinase 72.7.11.240.500
1aq1STUCyclin-dependent kinase 22.7.11.220.499
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.499
2wotZZGTGF-beta receptor type-12.7.11.300.498
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.498
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.497
4erwSTUCyclin-dependent kinase 22.7.11.220.497
2itzIREEpidermal growth factor receptor2.7.10.10.496
2vwu7X1Ephrin type-B receptor 42.7.10.10.496
4jr3KJREpidermal growth factor receptor2.7.10.10.496
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.496
2w05FRTCyclin-dependent kinase 22.7.11.220.495
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.495
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.495
4j97ACPFibroblast growth factor receptor 2/0.494
2ittAEEEpidermal growth factor receptor2.7.10.10.492
3gubGUBDeath-associated protein kinase 12.7.11.10.492
4jrvKJVEpidermal growth factor receptor2.7.10.10.492
1vjy460TGF-beta receptor type-12.7.11.300.491
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.491
3vjoANPEpidermal growth factor receptor2.7.10.10.491
4gk3L87Ephrin type-A receptor 32.7.10.10.491
2c6eHPMAurora kinase A2.7.11.10.490
2itpAEEEpidermal growth factor receptor2.7.10.10.490
4c62XWWTyrosine-protein kinase JAK2/0.490
5e8wSTUTGF-beta receptor type-12.7.11.300.490
1yvj4STTyrosine-protein kinase JAK32.7.10.20.489
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.489
2yn8STUEphrin type-B receptor 42.7.10.10.489
3gc9B45Mitogen-activated protein kinase 112.7.11.240.489
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.489
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.488
1rw8580TGF-beta receptor type-12.7.11.300.487
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.487
2h96893Mitogen-activated protein kinase 82.7.11.240.486
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.486
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.486
5aaaVGHALK tyrosine kinase receptor2.7.10.10.486
2j7t274Serine/threonine-protein kinase 102.7.11.10.485
2zybKSLTyrosine-protein kinase Lck2.7.10.20.485
3gxlQIGTGF-beta receptor type-12.7.11.300.485
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.484
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.484
3mtfA3FActivin receptor type-12.7.11.300.484
4hvg19QTyrosine-protein kinase JAK32.7.10.20.484
1xjdSTUProtein kinase C theta type2.7.11.130.483
1zyjBI5Mitogen-activated protein kinase 14/0.483
3mvl38PMitogen-activated protein kinase 14/0.482
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.482
2xvdAS6Ephrin type-B receptor 42.7.10.10.481
3ttjJBIMitogen-activated protein kinase 102.7.11.240.481
3w2sW2REpidermal growth factor receptor2.7.10.10.481
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.481
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.481
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.480
4c4h7RODual specificity protein kinase TTK2.7.12.10.479
1wvxBD4Death-associated protein kinase 12.7.11.10.478
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.478
3ac2KSETyrosine-protein kinase Lck2.7.10.20.478
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.478
4hvi19STyrosine-protein kinase JAK32.7.10.20.478
2xp2VGHALK tyrosine kinase receptor2.7.10.10.477
2y6o1N1Ephrin type-A receptor 42.7.10.10.477
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.477
4anqVGHALK tyrosine kinase receptor2.7.10.10.477
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.477
4c4g7RODual specificity protein kinase TTK2.7.12.10.477
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.477
2xa4AZ5Tyrosine-protein kinase JAK2/0.476
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.476
4ansVGHALK tyrosine kinase receptor2.7.10.10.476
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.476
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.476
1u4dDBQActivated CDC42 kinase 1/0.475
3oom507Activin receptor type-12.7.11.300.475
3s4qNK0Mitogen-activated protein kinase 14/0.475
3zh8C58Protein kinase C iota type2.7.11.130.475
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.475
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.475
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.474
2wouZZFTGF-beta receptor type-12.7.11.300.474
3w2rW2REpidermal growth factor receptor2.7.10.10.474
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.474
4i231C9Epidermal growth factor receptor2.7.10.10.474
4nk92K5Fibroblast growth factor receptor 1/0.474
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.473
1py5PY1TGF-beta receptor type-12.7.11.300.473
2eb3ANPEpidermal growth factor receptor2.7.10.10.473
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.473
3w18N13Aurora kinase A2.7.11.10.473
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.472
4bgg844Activin receptor type-12.7.11.300.472
1oecAA2Fibroblast growth factor receptor 2/0.471
2hog710Serine/threonine-protein kinase Chk12.7.11.10.471
3l8p0CEAngiopoietin-1 receptor2.7.10.10.471
2fgiPD1Fibroblast growth factor receptor 1/0.470
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
5dr9SKEAurora kinase A2.7.11.10.470
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.469
2py3ACPFibroblast growth factor receptor 2/0.469
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.469
4btkDTQTau-tubulin kinase 12.7.11.10.469
4f630S7Fibroblast growth factor receptor 1/0.469
4nj32KDCyclin-dependent kinase 22.7.11.220.469
2vww7X2Ephrin type-B receptor 42.7.10.10.468
2x9fX9FEphrin type-B receptor 42.7.10.10.468
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.468
3t8oATPRhodopsin kinase/0.468
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.468
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.467
2itxANPEpidermal growth factor receptor2.7.10.10.467
2j0j4STFocal adhesion kinase 12.7.10.20.467
2vwx7X4Ephrin type-B receptor 42.7.10.10.467
3upjU03Gag-Pol polyprotein/0.467
3uvp048Mitogen-activated protein kinase 14/0.467
4c02TAKActivin receptor type-12.7.11.300.467
4ewhT77Activated CDC42 kinase 1/0.467
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.467
1agwSU2Fibroblast growth factor receptor 1/0.466
1di8DTQCyclin-dependent kinase 22.7.11.220.466
2csnCKICasein kinase I homolog 12.7.11.10.466
2itvANPEpidermal growth factor receptor2.7.10.10.466
4b99R4LMitogen-activated protein kinase 72.7.11.240.466
4bcmT7ZCyclin-dependent kinase 22.7.11.220.466
4cd0AWJALK tyrosine kinase receptor2.7.10.10.466
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.466
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.465
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.465
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.465
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.465
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.465
4aotGW8Serine/threonine-protein kinase 102.7.11.10.465
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.465
1jpaANPEphrin type-B receptor 22.7.10.10.464
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.464
2pwlACPFibroblast growth factor receptor 2/0.464
2vu3LZECyclin-dependent kinase 22.7.11.220.464
2vx07X7Ephrin type-B receptor 42.7.10.10.464
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
3el4ROCGag-Pol polyprotein3.4.23.160.464
3hmm855TGF-beta receptor type-12.7.11.300.464
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.464
4jbqVX6Aurora kinase A2.7.11.10.464
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.463
2fvdLIACyclin-dependent kinase 22.7.11.220.463
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.463
2xru400Aurora kinase A2.7.11.10.463
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.463
2excJNKMitogen-activated protein kinase 102.7.11.240.462
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.462
2xyuQ9GEphrin type-A receptor 42.7.10.10.462
3tmz06XCytochrome P450 2B41.14.14.10.462
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.462
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.462
4g2fC07Ephrin type-A receptor 32.7.10.10.462
4jboWPHAurora kinase A2.7.11.10.462
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.461
2j0m4STFocal adhesion kinase 12.7.10.20.461
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.461
4wsqKSAAP2-associated protein kinase 12.7.11.10.461
5aabVGHALK tyrosine kinase receptor2.7.10.10.461
1mesDMPGag-Pol polyprotein3.4.23.160.460
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.460
2qo9ANPEphrin type-A receptor 32.7.10.10.460
2qoqANPEphrin type-A receptor 32.7.10.10.460
2vwz7X6Ephrin type-B receptor 42.7.10.10.460
3kf7L9GMitogen-activated protein kinase 14/0.460
4bb432WEphrin type-B receptor 42.7.10.10.460
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.460
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.460
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.459
2vwy7X5Ephrin type-B receptor 42.7.10.10.459
2vx17X8Ephrin type-B receptor 42.7.10.10.459
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.459
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.459
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.459
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.458
2yfxVGHALK tyrosine kinase receptor2.7.10.10.458
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4a6bQG8Gag-Pol polyprotein3.4.23.160.458
4c4iX20Dual specificity protein kinase TTK2.7.12.10.458
4ccbOFGALK tyrosine kinase receptor2.7.10.10.458
4fuxE75Mitogen-activated protein kinase 12.7.11.240.458
1eh4IC1Casein kinase I homolog 12.7.11.10.457
1k6cMK1Gag-Pol polyprotein3.4.23.160.457
1ke6LS2Cyclin-dependent kinase 22.7.11.220.457
1pkdUCNCyclin-dependent kinase 22.7.11.220.457
2c6hPXICytochrome P450 monooxygenase PikC/0.457
2i0ePDSProtein kinase C beta type2.7.11.130.457
2itwITQEpidermal growth factor receptor2.7.10.10.457
2j0lANPFocal adhesion kinase 12.7.10.20.457
2v7a627Tyrosine-protein kinase ABL12.7.10.20.457
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.457
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.457
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.457
4kiq1RAMitogen-activated protein kinase 14/0.457
1gih1PUCyclin-dependent kinase 22.7.11.220.456
1oi9N20Cyclin-dependent kinase 22.7.11.220.456
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.456
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.456
2i40BLZCyclin-dependent kinase 22.7.11.220.456
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.456
3a60STURibosomal protein S6 kinase beta-12.7.11.10.456
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.456
3dxjNE6DNA-directed RNA polymerase subunit beta/0.456
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.456
3eb0DRKUncharacterized protein/0.456
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4c61LMMTyrosine-protein kinase JAK2/0.456
4dymIYZActivin receptor type-12.7.11.300.456
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.455
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.455
2ckeIQUDeath-associated protein kinase 2/0.455
2etm7PYFocal adhesion kinase 12.7.10.20.455
2izsBRQCasein kinase I isoform gamma-32.7.11.10.455
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.455
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.455
3ac1KZITyrosine-protein kinase Lck2.7.10.20.455
3zep1NXTyrosine-protein kinase JAK32.7.10.20.455
4c58824Cyclin-G-associated kinase2.7.11.10.455
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.455
1hviA77Protease/0.454
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.454
2bheBRYCyclin-dependent kinase 22.7.11.220.454
2izrBRKCasein kinase I isoform gamma-32.7.11.10.454
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.454
3d7tSTUTyrosine-protein kinase CSK/0.454
3hllI45Mitogen-activated protein kinase 14/0.454
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.454
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4fnzNZFALK tyrosine kinase receptor2.7.10.10.454
4fv9E71Mitogen-activated protein kinase 12.7.11.240.454
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
5dt0SKEAurora kinase A2.7.11.10.454
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.453
2c3qGTXGlutathione S-transferase theta-12.5.1.180.453
2pvhP19Casein kinase II subunit alpha2.7.11.10.453
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.453
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.453
3aidARQGag-Pol polyprotein3.4.23.160.453
3erkSB4Mitogen-activated protein kinase 12.7.11.240.453
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3my5RFZCyclin-dependent kinase 22.7.11.220.453
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.453
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.453
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.453
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.453
4iarERM5-hydroxytryptamine receptor 1B/0.453
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
1h1r6CPCyclin-dependent kinase 22.7.11.220.452
1oiyN41Cyclin-dependent kinase 22.7.11.220.452
2henADPEphrin type-B receptor 22.7.10.10.452
2pzpACPFibroblast growth factor receptor 2/0.452
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.452
3ggfGVDSerine/threonine-protein kinase 26/0.452
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.452
4b7dQLECytochrome P450 monooxygenase PikC/0.452
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.452
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.452
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.451
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.451
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.451
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.451
4jqeANPCasein kinase II subunit alpha2.7.11.10.451
4kba1QMCasein kinase I isoform delta2.7.11.10.451
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.451
1h1s4SPCyclin-dependent kinase 22.7.11.220.450
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1idb0DOGag-Pol polyprotein/0.450
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.450
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.450
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.450
2ca0PXICytochrome P450 monooxygenase PikC/0.450
2w1eL0EAurora kinase A2.7.11.10.450
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.450
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.450
4bbfO19Tyrosine-protein kinase JAK2/0.450
4dgo0JWCasein kinase II subunit alpha2.7.11.10.450
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.450
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.450
5cshATPCasein kinase II subunit alpha2.7.11.10.450
5dpvSKEAurora kinase A2.7.11.10.450
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.449
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.449
2gs7ANPEpidermal growth factor receptor2.7.10.10.449
3gfeP37Mitogen-activated protein kinase 14/0.449
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
4e4m0NHTyrosine-protein kinase JAK2/0.449
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.449
4fod0UVALK tyrosine kinase receptor2.7.10.10.449
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.449
4grb0XGCasein kinase II subunit alpha2.7.11.10.449
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.449
5aacVGHALK tyrosine kinase receptor2.7.10.10.449
1c6x3INProtease/0.448
2bujSTUSerine/threonine-protein kinase 16/0.448
2izt23DCasein kinase I isoform gamma-32.7.11.10.448
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.448
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.448
4bchT7ZCyclin-dependent kinase 92.7.11.220.448
4ez50RSCyclin-dependent kinase 62.7.11.220.448
4iebANPCalmodulin-domain protein kinase 1/0.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.448
5k2bZMAAdenosine receptor A2a/0.448
1ykr628Cyclin-dependent kinase 22.7.11.220.447
2b7zMK1Gag-Pol polyprotein/0.447
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.447
2io6330Wee1-like protein kinase2.7.10.20.447
2iw94SPCyclin-dependent kinase 22.7.11.220.447
2pzrACPFibroblast growth factor receptor 2/0.447
2x1nX1NCyclin-dependent kinase 22.7.11.220.447
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.447
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.447
3ezvEZVCyclin-dependent kinase 22.7.11.220.447
3gu83GUDeath-associated protein kinase 12.7.11.10.447
3ttiKBIMitogen-activated protein kinase 102.7.11.240.447
1oguST8Cyclin-dependent kinase 22.7.11.220.446
1pyePM1Cyclin-dependent kinase 22.7.11.220.446
2xyeCXGGag-Pol polyprotein/0.446
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.446
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.446
3uli1N3Cyclin-dependent kinase 22.7.11.220.446
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.446
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.446
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.446
4j5j478Gag-Pol polyprotein3.4.23.160.446
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.445
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.445
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.445
2pvlP55Casein kinase II subunit alpha2.7.11.10.445
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.445
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.445
3flzFLZMitogen-activated protein kinase 14/0.445
3ogqAB1Pol polyprotein/0.445
3slkNDPPolyketide synthase extender module 2/0.445
3w2o03PEpidermal growth factor receptor2.7.10.10.445
4bcqTJFCyclin-dependent kinase 22.7.11.220.445
4hgt15GCasein kinase I isoform delta2.7.11.10.445
1k6pXN3Gag-Pol polyprotein3.4.23.160.444
1om1IQACasein kinase II subunit alpha2.7.11.10.444
2c7xNRBCytochrome P450 monooxygenase PikC/0.444
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2vd5BI8Myotonin-protein kinase2.7.11.10.444
3cktYDPGag-Pol polyprotein3.4.23.160.444
3drcMTXDihydrofolate reductase1.5.1.30.444
3gu6ADPDeath-associated protein kinase 12.7.11.10.444
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.444
3q92XNBKetohexokinase/0.444
3qa2XNAKetohexokinase/0.444
3rkb12ZCyclin-dependent kinase 22.7.11.220.444
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.444
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.444
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2p4yC03Peroxisome proliferator-activated receptor gamma/0.443
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.443
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3igoANPCalmodulin-domain protein kinase 1, putative/0.443
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.443
3qxpX64Cyclin-dependent kinase 22.7.11.220.443
4a6cQG9Gag-Pol polyprotein3.4.23.160.443
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.443
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.443
4ib4ERM5-hydroxytryptamine receptor 2B/0.443
1e9hINRCyclin-dependent kinase 22.7.11.220.442
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.442
2c475IDCasein kinase I isoform gamma-2/0.442
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.442
2qnqQN3Gag-Pol polyprotein3.4.23.160.442
2wleCOAPolysialic acid O-acetyltransferase/0.442
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.442
3b2tM33Fibroblast growth factor receptor 2/0.442
3du8553Glycogen synthase kinase-3 beta2.7.11.260.442
3le62BZCyclin-dependent kinase 22.7.11.220.442
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.442
3vjnANPEpidermal growth factor receptor2.7.10.10.442
3vt7VDXVitamin D3 receptor/0.442
4fnyI3KALK tyrosine kinase receptor2.7.10.10.442
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4j54G52Gag-Pol polyprotein3.4.23.160.442
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.442
4ye3G04Gag-Pol polyprotein3.4.23.160.442
5ap57RODual specificity protein kinase TTK2.7.12.10.442
5auwQUEDeath-associated protein kinase 12.7.11.10.442
1bdrIM1Gag-Pol polyprotein3.4.23.160.441
1yt9OISGag-Pol polyprotein/0.441
2f2cAP9Cyclin-dependent kinase 62.7.11.220.441
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.441
2gekGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.441
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.441
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.441
2iw84SPCyclin-dependent kinase 22.7.11.220.441
2qocANPEphrin type-A receptor 32.7.10.10.441
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.441
3biz61EWee1-like protein kinase2.7.10.20.441
3bu5ATPInsulin receptor2.7.10.10.441
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.441
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3em6017Gag-Pol polyprotein3.4.23.160.441
3hx4ANPCalmodulin-domain protein kinase 1/0.441
3lfqA28Cyclin-dependent kinase 22.7.11.220.441
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.441
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.441
4fx360KCyclin-dependent kinase 22.7.11.220.441
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4rupH97Vitamin D3 receptor A/0.441
2a4fAAUV-1 protease/0.440
2avsMK1Gag-Pol polyprotein3.4.23.160.440
2f8g017Gag-Pol polyprotein3.4.23.160.440
2j0k4STFocal adhesion kinase 12.7.10.20.440
2pz5ACPFibroblast growth factor receptor 2/0.440
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.440
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.440
4b7sQLECytochrome P450 monooxygenase PikC/0.440
4c4f7CEDual specificity protein kinase TTK2.7.12.10.440
4hni16WCasein kinase I isoform epsilon2.7.11.10.440