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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vhhVHHAvidin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3vhhVHHAvidin/1.000
3vhiVHIAvidin/0.650
3vgwNVZAvidin/0.617
3vhmNPKAvidin/0.594
2aviBTNAvidin/0.578
2fhnBNIAvidin-related protein 4/5/0.567
4bj8BTNAvidin/0.558
2zscBTNTamavidin2/0.543
1avdBTNAvidin/0.541
2fhlBNIAvidin-related protein 4/5/0.538
1sweBTNStreptavidin/0.535
2uywBTNAvd protein/0.535
1mepBTNStreptavidin/0.533
1swdBTNStreptavidin/0.525
2jgsBTNAvidin/0.521
1mk5BTNStreptavidin/0.520
1pqc444Oxysterols receptor LXR-beta/0.520
4bx7B4FStreptavidin/0.518
3q44D50M1 family aminopeptidase3.4.110.515
1swpBTQStreptavidin/0.514
1swnBTNStreptavidin/0.513
4uugPXGBranched-chain amino acid aminotransferase, putative/0.512
2uz2BTNAvd protein/0.505
2v2vV124-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.505
3qe2FMNNADPH--cytochrome P450 reductase/0.505
2izhBTNStreptavidin/0.503
3wypBSOStreptavidin/0.503
4yvbBTNStreptavidin/0.503
1ndjBTNStreptavidin/0.502
1swpBTNStreptavidin/0.502
3uyk0CXProbable NDP-rhamnosyltransferase/0.501
2wu4HBPAcetylcholinesterase3.1.1.70.497
4g5dNDPProstaglandin F synthase1.1.1.1880.496
1n43BTNStreptavidin/0.495
1sriDMBStreptavidin/0.495
1pq944BOxysterols receptor LXR-beta/0.494
1srfMTBStreptavidin/0.494
1df8BTNStreptavidin/0.493
2xlrFADPutative flavin-containing monooxygenase/0.492
1nc9IMIStreptavidin/0.491
4rquNADAlcohol dehydrogenase class-P/0.491
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.490
5a0112VO-glycosyltransferase/0.488
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.487
1s3uTQDDihydrofolate reductase1.5.1.30.487
1y52BTNAvidin-related protein 4/5/0.487
2rtmIMIStreptavidin/0.487
2c4iBTNAvidin/0.484
1q84TZ4Acetylcholinesterase3.1.1.70.483
3up0D7SaceDAF-12/0.483
3ny9JSZBeta-2 adrenergic receptor/0.483
1p8dCO1Oxysterols receptor LXR-beta/0.482
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.482
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.482
1srgMHBStreptavidin/0.481
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.481
4ggzBTNBll1558 protein/0.481
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.481
1c7oPPGHemolysin/0.480
1fvpFMANon-fluorescent flavoprotein/0.480
1galFADGlucose oxidase1.1.3.40.480
4hb9FADUncharacterized protein/0.480
4phlPILPhosphodiesterase/0.480
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.479
4j7hTRHPCZA361.3/0.479
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.477
4bcsBTNAvidin-related protein 4/5/0.477
4oztP1AEcdysone receptor, putative/0.476
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.475
1m2hAPRNAD-dependent protein deacylase 1/0.475
1n9mBTNStreptavidin/0.475
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.475
4e2xTYDMethyltransferase/0.475
4gd9BTNStreptavidin/0.475
1d9i00PProthrombin3.4.21.50.474
1swrBTNStreptavidin/0.474
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.474
2xlpFADPutative flavin-containing monooxygenase/0.474
3lkhLT6Genome polyprotein2.7.7.480.474
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.473
2bsxNOSPurine nucleoside phosphorylase/0.473
2fznFADBifunctional protein PutA1.5.5.20.473
3bg7FADPyranose 2-oxidase/0.473
4gl4NAIAlcohol dehydrogenase class-3/0.473
4pnmNU1Tankyrase-22.4.2.300.473
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.472
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.472
1luqBTNStreptavidin/0.472
3wznBTNStreptavidin/0.472
4an4DUDPutative glycosyl transferase/0.472
1hb1OCVIsopenicillin N synthase1.21.3.10.471
1mp0NADAlcohol dehydrogenase class-31.1.1.10.471
2vbpVB1Isopenicillin N synthase1.21.3.10.471
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.471
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.471
4gi5FADPutative NAD(P)H dehydrogenase (Quinone)/0.471
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.470
3tdaPN0Cytochrome P450 2D6/0.470
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.470
1nqmBTNStreptavidin/0.469
1nzq162Prothrombin3.4.21.50.469
1ta6177Prothrombin3.4.21.50.469
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.469
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3uayADNPurine nucleoside phosphorylase DeoD-type/0.469
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.469
1g8jMGDArsenite oxidase subunit AioA1.20.9.10.468
1nbiSAMGlycine N-methyltransferase2.1.1.200.468
2dhfDZFDihydrofolate reductase1.5.1.30.468
2rtqIMIStreptavidin/0.468
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.468
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.468
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.468
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.467
3sf6FDAGlutaryl-CoA dehydrogenase/0.467
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.467
4mo2FDAUDP-galactopyranose mutase/0.467
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.467
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.467
1bk0ACVIsopenicillin N synthase1.21.3.10.466
1w6hTITPlasmepsin-23.4.23.390.466
1z71L17Prothrombin3.4.21.50.466
2rtfBTNStreptavidin/0.466
2zryFNRIsopentenyl-diphosphate delta-isomerase/0.466
3ndjJHZMethyltransferase/0.466
4x28FDAAcyl-CoA dehydrogenase FadE26/0.466
4x28FDAAcyl-CoA dehydrogenase FadE27/0.466
4xd1T3QQdtf/0.466
5dp2NAPCurF/0.466
1mczRMNBenzoylformate decarboxylase4.1.1.70.465
1od10QSEndothiapepsin3.4.23.220.465
2eixFADNADH-cytochrome b5 reductase/0.465
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.465
4bttVYRCoagulation factor X3.4.21.60.465
4dk70KSOxysterols receptor LXR-beta/0.465
4dpi0N1Beta-secretase 13.4.23.460.465
4e32DWNMethyltransferase/0.465
5a4vQUEGlutathione S-transferase F22.5.1.180.465
1e2nRCAThymidine kinase/0.464
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.464
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.464
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.464
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.464
1yc2APRNAD-dependent protein deacylase 2/0.464
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
3q7fED2Uncharacterized protein/0.464
1aiqCB3Thymidylate synthase/0.463
1d3pBT3Prothrombin3.4.21.50.463
1o5rFR9Adenosine deaminase3.5.4.40.463
1yqxNAPSinapyl alcohol dehydrogenase/0.463
2hizLIJBeta-secretase 13.4.23.460.463
2izfBTNStreptavidin/0.463
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
3k5fAYHBeta-secretase 13.4.23.460.463
4ey7E20Acetylcholinesterase3.1.1.70.463
5jscFADPutative acyl-CoA dehydrogenase/0.463
1stpBTNStreptavidin/0.462
1swtBTNStreptavidin/0.462
2y6fM9FIsopenicillin N synthase1.21.3.10.462
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.462
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.462
4m9aFDAAcyl-CoA dehydrogenase/0.462
3eufBAUUridine phosphorylase 1/0.461
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.461
1n5dNDPCarbonyl reductase [NADPH] 1/0.460
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.460
2z1qFADAcyl-CoA dehydrogenase/0.460
3gwfFADCyclohexanone monooxygenase/0.460
4rvgTYDD-mycarose 3-C-methyltransferase/0.460
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.460
1gvw0EMEndothiapepsin3.4.23.220.459
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.459
1rxhBNIStreptavidin/0.459
1sreHABStreptavidin/0.459
1z7yAA5Cysteine synthase 12.5.1.470.459
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.459
2iko7IGRenin3.4.23.150.459
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.459
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.459
3q43D66M1 family aminopeptidase3.4.110.459
3q9bB3NAcetylpolyamine amidohydrolase/0.459
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.459
5jlaNADPutative short-chain dehydrogenase/reductase/0.459
1icqOPD12-oxophytodienoate reductase 11.3.1.420.458
1knrFADL-aspartate oxidase1.4.3.160.458
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
3edjBCDCyclomaltodextrinase/0.458
3vqrFADPutative oxidoreductase/0.458
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.458
4dneDTBStreptavidin/0.458
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.458
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.458
4ieiADPGene 2 protein/0.458
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.458
5dcyNAPIridoid synthase1.3.1.990.458
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1ig0VIBThiamine pyrophosphokinase2.7.6.20.457
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.457
1m2gAPRNAD-dependent protein deacylase 1/0.457
1pd9CO4Dihydrofolate reductase1.5.1.30.457
2r0pK2CPutative FAD-monooxygenase/0.457
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.457
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.457
3n0hTOPDihydrofolate reductase1.5.1.30.457
3w8wFADPutative FAD-dependent oxygenase EncM/0.457
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.457
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.457
4kwcSAHMethyltransferase domain family/0.457
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.457
5iqeGNPBifunctional AAC/APH2.3.10.457
1e1kFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.456
1ejeFMNProtein MTH_152/0.456
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.456
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.456
2x95X95Angiotensin-converting enzyme3.4.15.10.456
2xtbKRMAdenosine kinase, putative/0.456
3nw3MU2Peptidoglycan recognition protein 1/0.456
3prsRITEndothiapepsin3.4.23.220.456
3w78CBDFMN-dependent NADH-azoreductase/0.456
4bxk1IUAngiotensin-converting enzyme3.2.10.456
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.456
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4z28BTNHoefavidin/0.456
3sn6P0GBeta-2 adrenergic receptor/0.456
1h36R88Squalene--hopene cyclase4.2.1.1290.455
1k8cNAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.455
1zgaHMKIsoflavone 4'-O-methyltransferase/0.455
2c29NAPDihydroflavonol 4-reductase/0.455
2ifaFMNUncharacterized protein/0.455
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.455
2rtrIMIStreptavidin/0.455
2yg5FADPutrescine oxidase/0.455
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3i0pNADMalate dehydrogenase, putative/0.455
3u9y09LTankyrase-22.4.2.300.455
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.455
4ap3NAPSteroid monooxygenase/0.455
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.454
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.454
2qtrNXXProbable nicotinate-nucleotide adenylyltransferase/0.454
2rtnIMIStreptavidin/0.454
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.454
2xvfFADPutative flavin-containing monooxygenase/0.454
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.454
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3oqkS52Renin3.4.23.150.454
3rnoNAPNAD(P)H-hydrate epimerase5.1.99.60.454
3tfyCOAN-alpha-acetyltransferase 502.3.10.454
3up3XCAaceDAF-12/0.454
4araC56Acetylcholinesterase3.1.1.70.454
4irnFADAnaB/0.454
4j7gTRHPCZA361.3/0.454
4kxjP34Nucleoprotein/0.454
4plpNADHomospermidine synthase2.5.1.440.454
4wbdADPPutative cysteine ligase BshC/0.454
4xrgNADHomospermidine synthase2.5.1.440.454
5iu86DZAdenosine receptor A2a/0.454
1pk92FAPurine nucleoside phosphorylase DeoD-type/0.453
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.453
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.453
1zq5E04Aldo-keto reductase family 1 member C3/0.453
2cf8ESHProthrombin3.4.21.50.453
2cmfF11Acetylcholinesterase3.1.1.70.453
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.453
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.453
3r95ACOMccE protein/0.453
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.453
3vf60H6Glucokinase2.7.1.20.453
3zkyWT4Isopenicillin N synthase1.21.3.10.453
4eb5PLPCysteine desulfurase IscS 2/0.453
4kqqVPPPeptidoglycan D,D-transpeptidase FtsI/0.453
7catNDPCatalase1.11.1.60.453
1eq2ADQADP-L-glycero-D-manno-heptose-6-epimerase/0.452
1eveE20Acetylcholinesterase3.1.1.70.452
1j4jACOAcetyltransferase2.3.10.452
1p52ADPArginine kinase2.7.3.30.452
1tiqCOASpermidine/spermine N(1)-acetyltransferase/0.452
1w06W05Isopenicillin N synthase1.21.3.10.452
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.452
3v0o4GWHisto-blood group ABO system transferase/0.452
3w5rLOAVitamin D3 receptor/0.452
4e2yJHZMethyltransferase/0.452
4fam0SZAldo-keto reductase family 1 member C3/0.452
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.452
4nv14TGFormyl transferase/0.452
1dr3HBIDihydrofolate reductase1.5.1.30.451
1drfFOLDihydrofolate reductase1.5.1.30.451
1f8wFADNADH peroxidase1.11.1.10.451
1qjfACSIsopenicillin N synthase1.21.3.10.451
2culFADGidA-related protein/0.451
3cobADPKinesin heavy chain-like protein/0.451
3qm4PN0Cytochrome P450 2D6/0.451
3ukoNADAlcohol dehydrogenase class-3/0.451
4dveBTNBiotin transporter BioY/0.451
4psbGA3Cytokinin-specific binding protein/0.451
4q0kGA3Phytohormone-binding protein/0.451
4xulGTPUncharacterized protein mg662/0.451
4n4wSNTSmoothened homolog/0.451
3p0gP0GBeta-2 adrenergic receptor/0.451
1gvt2ZSEndothiapepsin3.4.23.220.450
1hb3SCVIsopenicillin N synthase1.21.3.10.450
1lcwSHMStreptavidin/0.450
1o6qR17Squalene--hopene cyclase4.2.1.1290.450
2aclL05Oxysterols receptor LXR-alpha/0.450
2akoADPGlutamate 5-kinase/0.450
2flhZEACytokinin-specific binding protein/0.450
2g226IGRenin3.4.23.150.450
2nomDUTPoly(A) polymerase, putative/0.450
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.450
2vcmM11Isopenicillin N synthase1.21.3.10.450
2vqbFADPutative flavin-containing monooxygenase/0.450
2xugTZ4Acetylcholinesterase3.1.1.70.450
2y3fBTNStreptavidin/0.450
2yg4FADPutrescine oxidase/0.450
2yutNAPPutative short-chain oxidoreductase/0.450
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.450
3oxk5GPHistidine triad nucleotide-binding protein30.450
3pqbVGPPutative oxidoreductase/0.450
4gevCB3Thymidylate synthase/0.450
4jtdNAPVoltage-gated potassium channel subunit beta-2/0.450
4twnB96Ephrin type-A receptor 32.7.10.10.450
5jtbZMAAdenosine receptor A2a/0.450
4u140HKMuscarinic acetylcholine receptor M3/0.450
1ah4NAPAldose reductase1.1.1.210.449
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.449
1t57FMNConserved protein/0.449
1zgbA1EAcetylcholinesterase3.1.1.70.449
2oadGTBGlutathione S-transferase P 12.5.1.180.449
2w6cBM4Acetylcholinesterase3.1.1.70.449
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.449
3hl0NADMaleylacetate reductase/0.449
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.449
4b67NAPL-ornithine N(5)-monooxygenase/0.449
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.449
4iarERM5-hydroxytryptamine receptor 1B/0.449
4msg2C6Tankyrase-12.4.2.300.449
4n3l2FNProthrombin3.4.21.50.449
4xczT3QQdtf/0.449
1d3dBZTProthrombin3.4.21.50.448
1pr1FMBPurine nucleoside phosphorylase DeoD-type/0.448
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.448
1ut6A8NAcetylcholinesterase3.1.1.70.448
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2ph6712Beta-secretase 13.4.23.460.448
2r9w23CBeta-lactamase3.5.2.60.448
2rtgBTNStreptavidin/0.448
3d4bDZDNAD-dependent protein deacetylase/0.448
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3fznD7KBenzoylformate decarboxylase4.1.1.70.448
3nxqRX4Angiotensin-converting enzyme3.2.10.448
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.448
4ambDUDPutative glycosyl transferase/0.448
5fuwTHMThymidine kinase, putative/0.448
1dhfFOLDihydrofolate reductase1.5.1.30.447
1e82M90Endothiapepsin3.4.23.220.447
1g63FMNEpidermin decarboxylase4.1.10.447
1r2jFADFkbI/0.447
1rneC60Renin3.4.23.150.447
1v35NAIEnoyl-ACP reductase/0.447
2bn4FMNNADPH--cytochrome P450 reductase/0.447
2bu9HFVIsopenicillin N synthase1.21.3.10.447
2vkmBSDBeta-secretase 13.4.23.460.447
2wf4ZY4Beta-secretase 13.4.23.460.447
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.447
2z3uCRRCytochrome P450/0.447
3af1GDPPantothenate kinase2.7.1.330.447
3bi6396Wee1-like protein kinase2.7.10.20.447
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3lqfNADGalactitol dehydrogenase/0.447
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.447
4bfsZVSPantothenate kinase2.7.1.330.447
4fse0VABeta-secretase 13.4.23.460.447
4mk928RGenome polyprotein2.7.7.480.447
4tm3FADKtzI/0.447
1c9wNAPAldose reductase-related protein 2/0.446
1fwmCB3Thymidylate synthase/0.446
1ja0FMNNADPH--cytochrome P450 reductase/0.446
1ry8RUTAldo-keto reductase family 1 member C3/0.446
1x8lOXRRetinol dehydratase/0.446
1zg32HIIsoflavone 4'-O-methyltransferase/0.446
2hq9FADMll6688 protein/0.446
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.446
2ozrGG1Collagenase 33.4.240.446
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.446
2xujTZ5Acetylcholinesterase3.1.1.70.446
3n87N873-dehydroquinate dehydratase4.2.1.100.446
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.446
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.446
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.446
4gdcNDPUDP-galactopyranose mutase/0.446
4knzCB3Thymidylate synthase/0.446
4l5b1UXDeoxycytidine kinase2.7.1.740.446
5f12FMNNAD(P)H dehydrogenase (quinone)/0.446
1lkeDOGBilin-binding protein/0.445
1m2jAPRNAD-dependent protein deacylase 1/0.445
1me6IVSPlasmepsin-23.4.23.390.445
1mvtDTMDihydrofolate reductase1.5.1.30.445
1v48HA1Purine nucleoside phosphorylase2.4.2.10.445
2ebaFADPutative glutaryl-CoA dehydrogenase/0.445
2fj1CTCTetracycline repressor protein class D/0.445
2rtoIMIStreptavidin/0.445
3a1l2CCCytochrome P450/0.445
3mk6ACOPantothenate kinase 32.7.1.330.445
3nj8NJ8Enoyl-acyl carrier reductase/0.445
3nmpPYVAbscisic acid receptor PYL2/0.445
3rl45GPMetallophosphoesterase MPPED23.10.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
4bj9UHBTankyrase-22.4.2.300.445
4e2zJHZMethyltransferase/0.445
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.444
1l2oADPMyosin heavy chain, striated muscle/0.444
1q6t600Tyrosine-protein phosphatase non-receptor type 13.1.3.480.444
2a3bCFFEndochitinase B13.2.1.140.444
3g86T18Genome polyprotein2.7.7.480.444
3gf4UPGUDP-galactopyranose mutase5.4.99.90.444
3s7a684Dihydrofolate reductase1.5.1.30.444
3t8wDGZM17 leucyl aminopeptidase/0.444
4g8bHL6Alpha/beta hydrolase fold protein/0.444
4jseQJ2Nitric oxide synthase, brain1.14.13.390.444
4nv10FXFormyl transferase/0.444
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.444
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.443
1hrvSDZGenome polyprotein/0.443
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.443
1psa0ZLPepsin A3.4.23.10.443
1qorNDPQuinone oxidoreductase 1/0.443
1s7gAPRNAD-dependent protein deacylase 2/0.443
1u65CP0Acetylcholinesterase3.1.1.70.443
2xufTZ4Acetylcholinesterase3.1.1.70.443
2xviFADPutative flavin-containing monooxygenase/0.443
2yg3FADPutrescine oxidase/0.443
3bj7COADiamine acetyltransferase 1/0.443
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.443
3lnbCOAN-acetyltransferase family protein/0.443
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3ojxFADNADPH--cytochrome P450 reductase/0.443
3vt7VDXVitamin D3 receptor/0.443
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.443
4gsuDWZL,D-transpeptidase 22.3.20.443
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.443
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.443
4qa2SHHHistone deacetylase 83.5.1.980.443
4usrFADMonooxygenase/0.443
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.443
5jqhCAUBeta-2 adrenergic receptor/0.443
1nbhSAMGlycine N-methyltransferase2.1.1.200.442
1zdwFLVPrenyltransferase/0.442
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.442
2g0bNLTLong-chain N-acyl amino acid synthase/0.442
2he5NDPAldo-keto reductase family 1 member C211.1.10.442
3arvSAUChitinase A/0.442
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.442
3lbnGNPGTPase HRas/0.442
3lpgZ78Beta-glucuronidase3.2.1.310.442
4dbs0HVAldo-keto reductase family 1 member C3/0.442
4dc1NDPPutative ketoacyl reductase1.3.10.442
4epq0RRPoly(ADP-ribose) glycohydrolase/0.442
4h3f10OBeta-secretase 13.4.23.460.442
4kwhNAPReductase homolog/0.442
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.442
4x7ySAHMycinamicin III 3''-O-methyltransferase2.1.1.2370.442
4ykgNADAlkyl hydroperoxide reductase subunit F1.8.10.442
4z24FADPutative GMC-type oxidoreductase R13510.442
5g53NECAdenosine receptor A2a/0.442
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.441
1lf3EH5Plasmepsin-23.4.23.390.441
1v5y4HCMajor NAD(P)H-flavin oxidoreductase1.6.990.441
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.441
2cf9348Prothrombin3.4.21.50.441
2j3qTFLAcetylcholinesterase3.1.1.70.441
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
3d7zGK5Mitogen-activated protein kinase 14/0.441
3iesM24Luciferin 4-monooxygenase1.13.12.70.441
3nx4NAPPutative oxidoreductase/0.441
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.441
3tdkUPGUDP-glucose 6-dehydrogenase1.1.1.220.441
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.441
4ap1FADSteroid monooxygenase/0.441
4b7zQ4QAcetylcholinesterase3.1.1.70.441
4bftZVTPantothenate kinase2.7.1.330.441
4bquCLRJapanin/0.441
4dc0NDPPutative ketoacyl reductase1.3.10.441
4djy0KRBeta-secretase 13.4.23.460.441
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.441
4lxk1YTBeta-secretase 13.4.23.460.441
5dbgNADIridoid synthase1.3.1.990.441
4s0vSUVOrexin receptor type 2/0.441
3ny8JRZBeta-2 adrenergic receptor/0.441
1blzACVIsopenicillin N synthase1.21.3.10.440
1c4yIH3Prothrombin3.4.21.50.440
1rkwPNTHTH-type transcriptional regulator QacR/0.440
1w4lGL8Acetylcholinesterase3.1.1.70.440
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.440
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.440
2ha6SCKAcetylcholinesterase3.1.1.70.440
2ii4COALipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.1680.440
2il2LIXRenin3.4.23.150.440
2jf0HBPAcetylcholinesterase3.1.1.70.440
2uuk897Prothrombin3.4.21.50.440
2xgs44PUncharacterized protein/0.440
2xlsFADPutative flavin-containing monooxygenase/0.440
2zjmF1MBeta-secretase 13.4.23.460.440
3axbFADPutative oxidoreductase/0.440
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3cb2GDPTubulin gamma-1 chain/0.440
3d91REMRenin3.4.23.150.440
3f63GTXGlutathione transferase GST1-4/0.440
3lpkZ76Beta-secretase 13.4.23.460.440
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.440
3rf7NADIron-containing alcohol dehydrogenase/0.440
3ry2BTNStreptavidin/0.440
3skgPB8Beta-secretase 13.4.23.460.440
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.440
3w0uHPWLactoylglutathione lyase4.4.1.50.440
3w5uFADFerredoxin/0.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4bmvNAPShort-chain dehydrogenase/0.440
4jln18VDeoxycytidine kinase2.7.1.740.440
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.440
5iqiGNPBifunctional AAC/APH2.3.10.440