sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3t0z | ATP | Heat shock protein HSP 90-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 1.000 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.643 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.640 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.635 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.632 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.630 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.614 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.607 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.607 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.599 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.598 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.595 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.591 | |
| 2o1u | ANP | Endoplasmin | / | 0.587 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.581 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.580 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.580 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.579 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.579 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.578 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.576 | |
| 2hch | N5A | Endoplasmin | / | 0.574 | |
| 2exl | GDM | Endoplasmin | / | 0.566 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.566 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.566 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 1yt0 | ADP | Endoplasmin | / | 0.561 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.561 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.561 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.561 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.557 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.556 | |
| 1u2o | NEC | Endoplasmin | / | 0.552 | |
| 2fyp | RDE | Endoplasmin | / | 0.552 | |
| 2o1v | ADP | Endoplasmin | / | 0.552 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.551 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.550 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.549 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.544 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.544 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.544 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.543 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.541 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.540 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.538 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.537 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.537 | |
| 3ied | AN2 | HSP90 | / | 0.537 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.535 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.533 | |
| 1u0y | PA7 | Endoplasmin | / | 0.532 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 1qy8 | RDI | Endoplasmin | / | 0.531 | |
| 1u0z | RDC | Endoplasmin | / | 0.531 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.531 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.530 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 2esa | GDM | Endoplasmin | / | 0.530 | |
| 2hg1 | N5O | Endoplasmin | / | 0.527 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.526 | |
| 2gfd | RDA | Endoplasmin | / | 0.525 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.525 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.525 | |
| 1ysz | NEC | Endoplasmin | / | 0.523 | |
| 2gqp | PA7 | Endoplasmin | / | 0.523 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.522 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.522 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.520 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 3q5l | KX2 | Heat shock protein 83-1 | / | 0.518 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.517 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.516 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.514 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.514 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 1qy5 | NEC | Endoplasmin | / | 0.506 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 2vwc | BC2 | ATP-dependent molecular chaperone HSP82 | / | 0.504 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.502 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.501 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.499 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.498 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.497 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.496 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.493 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.487 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.487 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.484 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.480 | |
| 2bu2 | ATP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.479 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.479 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 1i58 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.474 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.474 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.473 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.472 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.471 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.471 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.470 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.469 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.469 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.469 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.469 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.468 | |
| 3m9v | TYD | FAD-dependent oxidoreductase | / | 0.468 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3u9e | COA | Lmo1369 protein | / | 0.465 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.464 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.464 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.464 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.463 | |
| 1z59 | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.463 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.462 | |
| 2yi6 | 6QM | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.462 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.461 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.461 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.459 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.459 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.459 | |
| 1b38 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.458 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.458 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.458 | |
| 3w2n | ROD | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.458 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.458 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.456 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.455 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.455 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.455 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 3e8c | G96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 1mx0 | ANP | Type 2 DNA topoisomerase 6 subunit B | / | 0.453 | |
| 4y9r | NAP | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 1hk2 | T44 | Serum albumin | / | 0.452 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.452 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.452 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.452 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.451 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.451 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.450 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.450 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.450 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.450 | |
| 4iaz | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.449 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.449 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.449 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.449 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.449 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.448 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.448 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.448 | |
| 4oae | CLM | Uncharacterized protein | / | 0.448 | |
| 1ao0 | ADP | Amidophosphoribosyltransferase | / | 0.447 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.447 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.447 | |
| 2ves | GVR | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.447 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.447 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.447 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.447 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.447 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.446 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.446 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.445 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.445 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.445 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.445 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.444 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.444 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 3t80 | CTN | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.444 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.444 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.443 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.443 | |
| 3g6w | GTP | Uracil phosphoribosyltransferase | 2.4.2.9 | 0.443 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4egn | TWO | Cytochrome P450 | / | 0.443 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.443 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.442 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.442 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.442 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.442 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4y7c | NAP | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.441 | |
| 1qxo | FMN | Chorismate synthase | / | 0.441 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3eof | FMN | Putative oxidase | / | 0.441 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3tdl | 11D | Serum albumin | / | 0.441 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.441 | |
| 5ftc | ADP | TPR domain protein | / | 0.441 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.440 | |
| 1u5r | ATP | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.440 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.440 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.440 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.440 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.440 | |
| 3rkr | NAP | Uncharacterized protein | / | 0.440 | |
| 3s1c | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.440 |