sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3nmn | PYV | Abscisic acid receptor PYL1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 1.000 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.593 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.587 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.585 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.569 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.566 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.563 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.554 | |
| 3kb3 | A8S | Abscisic acid receptor PYL2 | / | 0.545 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.536 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.534 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.534 | |
| 4oic | A8S | Bet v I allergen-like | / | 0.533 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.531 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.529 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.528 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.521 | |
| 3k3k | A8S | Abscisic acid receptor PYR1 | / | 0.520 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.513 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.511 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.500 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.493 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.489 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 3k90 | A8S | Abscisic acid receptor PYR1 | / | 0.488 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.483 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.482 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.481 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.481 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.480 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.479 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.478 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.477 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 1eio | GCH | Gastrotropin | / | 0.473 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 3qn1 | A8S | Abscisic acid receptor PYR1 | / | 0.473 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 5a3c | NAD | SIR2 family protein | / | 0.472 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.470 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.470 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.469 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.466 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.465 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.465 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.465 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.464 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.464 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.464 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.464 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1fml | RTL | Retinol dehydratase | / | 0.463 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.463 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.463 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.462 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.462 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.462 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.461 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.461 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.461 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.460 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.460 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.460 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.460 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.459 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 4pd6 | URI | Nucleoside permease | / | 0.459 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.458 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.458 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.458 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.458 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.458 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.457 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 3kdj | A8S | Abscisic acid receptor PYL1 | / | 0.457 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.457 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.456 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.456 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.456 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.456 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.456 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.455 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.455 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.455 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.454 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.454 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.454 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.453 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.453 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.453 | |
| 3gob | HXX | DdmC | / | 0.453 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.453 | |
| 4v12 | POG | MaoC like domain protein | / | 0.453 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.452 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.452 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.452 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.452 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.452 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.452 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.452 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.452 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.452 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.452 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.452 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.452 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.452 | |
| 5a3b | APR | SIR2 family protein | / | 0.452 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.451 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1uof | PNN | Deacetoxycephalosporin C synthase | 1.14.20.1 | 0.451 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.451 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.451 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.451 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.451 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.451 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.450 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.450 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.450 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3dmg | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.450 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4a28 | ADP | Kinesin-like protein KIF11 | / | 0.450 | |
| 4c68 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.450 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.450 | |
| 4pda | CTN | Nucleoside permease | / | 0.450 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.449 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.449 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.449 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.449 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.449 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.449 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.449 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.449 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.448 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.448 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.448 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.448 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.448 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.448 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.448 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.447 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.447 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.447 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.447 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.447 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.446 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3nmv | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.446 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.446 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.446 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.445 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.445 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.445 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.445 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.445 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.445 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.445 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.445 | |
| 3v49 | PK0 | Androgen receptor | / | 0.445 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.445 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.444 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.444 | |
| 1vzb | UMP | Thymidylate synthase | / | 0.444 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.444 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.444 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.444 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.444 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.443 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.443 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.443 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.443 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.443 | |
| 4fa6 | 0TA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.443 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.443 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.442 | |
| 1ppj | ANY | Cytochrome b | / | 0.442 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.442 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.442 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.442 | |
| 2amb | 17H | Androgen receptor | / | 0.442 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3eva | SAH | Genome polyprotein | 2.1.1.56 | 0.442 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 3zly | YSO | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.442 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.441 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.441 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.441 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.441 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.441 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.441 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 1m8g | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.440 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.440 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2y3r | TIR | TamL | / | 0.440 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.440 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.440 | |
| 3u9e | COA | Lmo1369 protein | / | 0.440 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.440 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |