sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3lbf | SAH | Protein-L-isoaspartate O-methyltransferase | 2.1.1.77 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3lbf | SAH | Protein-L-isoaspartate O-methyltransferase | 2.1.1.77 | 1.000 | |
| 4o29 | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.553 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.488 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.483 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.483 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.482 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.479 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.474 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.474 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.472 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.472 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.471 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1nv9 | SAH | Release factor glutamine methyltransferase | 2.1.1.297 | 0.469 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.469 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.469 | |
| 1kr5 | SAH | Protein-L-isoaspartate(D-aspartate) O-methyltransferase | 2.1.1.77 | 0.468 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.468 | |
| 3q87 | SAM | N6 ADENINE SPECIFIC DNA METHYLASE (METHYLTRANSFERASE SUPERFAMILY) | / | 0.468 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.468 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.467 | |
| 2plw | SAM | Ribosomal RNA methyltransferase, putative | / | 0.467 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.467 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.465 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.464 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.463 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.463 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.462 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.462 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.462 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.462 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.462 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.462 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.461 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.461 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.461 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.461 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.460 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.460 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.459 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.459 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.459 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.459 | |
| 3egv | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.459 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.458 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.458 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.457 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.457 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.457 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.457 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.457 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.457 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.457 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4l9k | EHF | Serum albumin | / | 0.457 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.456 | |
| 1sg9 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.456 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.456 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.455 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.455 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.455 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.455 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.455 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.455 | |
| 4kvz | SAH | PtnL protein | / | 0.455 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.455 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.455 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.455 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.454 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.454 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.454 | |
| 3up3 | XCA | aceDAF-12 | / | 0.454 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.454 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.454 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.453 | |
| 3a3g | DLZ | Lumazine protein | / | 0.453 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.453 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.453 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.453 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.453 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.453 | |
| 5bxy | SAH | Putative RNA methylase family UPF0020 | / | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.452 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.452 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.451 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.451 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.451 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.451 | |
| 3grr | SAH | Probable ribosomal RNA small subunit methyltransferase A | / | 0.451 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.451 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.450 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.449 | |
| 2dsi | SAH | Diphthine synthase | / | 0.449 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.449 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.449 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.449 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.449 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.449 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.448 | |
| 1vq1 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.448 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.448 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.448 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.448 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.448 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.447 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.447 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.447 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 4jal | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.447 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.447 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.446 | |
| 1qan | SAH | rRNA adenine N-6-methyltransferase | 2.1.1.184 | 0.446 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.446 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.446 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.446 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.446 | |
| 5kje | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.445 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.445 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.445 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.445 | |
| 3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.445 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.444 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.444 | |
| 4eke | D1I | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.444 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.444 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.444 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 1gqt | ACP | Ribokinase | / | 0.443 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.443 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.443 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.443 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.443 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.443 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.443 | |
| 4hs4 | FMN | Chromate reductase | / | 0.443 | |
| 4lj6 | ACP | Chaperone protein ClpB | / | 0.443 | |
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.443 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.443 | |
| 1cg0 | IMO | Adenylosuccinate synthetase | / | 0.442 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.442 | |
| 2egb | SAH | Diphthine synthase | / | 0.442 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.442 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.442 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.441 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.441 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.441 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.441 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.441 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.441 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.441 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.441 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3uce | NDP | Dehydrogenase | / | 0.441 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.441 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.441 | |
| 4fcw | ADP | Chaperone protein ClpB | / | 0.441 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.441 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
| 1bc5 | SAH | Chemotaxis protein methyltransferase | 2.1.1.80 | 0.440 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.440 | |
| 2en5 | SAH | Diphthine synthase | / | 0.440 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.440 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.440 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.440 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.440 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.440 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.440 |