sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 1.000 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.600 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.568 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.566 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.566 | |
| 1xk9 | P34 | Exotoxin A | 2.4.2.36 | 0.560 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.560 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.554 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.553 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.549 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.547 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.546 | |
| 4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.546 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.546 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.541 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.541 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.539 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.539 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.538 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.536 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.535 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.532 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.531 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.531 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.530 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.530 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.530 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.528 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.527 | |
| 1zm4 | TAD | Exotoxin A | 2.4.2.36 | 0.526 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.526 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.526 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.518 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.515 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.513 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.511 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.510 | |
| 3q9o | NAD | Cholix toxin | 2.4.2.36 | 0.510 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.510 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.507 | |
| 4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.503 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.499 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.499 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.498 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.498 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.493 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.491 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.490 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.489 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.488 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.488 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.487 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.487 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.486 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.486 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.485 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.485 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.485 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.484 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.483 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 3b8h | NAD | Exotoxin A | 2.4.2.36 | 0.481 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.480 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.480 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.478 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.478 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 4hlm | 16S | Tankyrase-2 | 2.4.2.30 | 0.478 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.478 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.477 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.477 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.476 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.474 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.474 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.473 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.473 | |
| 1ddt | APU | Diphtheria toxin | / | 0.472 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.472 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 2h8x | FMN | XenA | / | 0.471 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.471 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.471 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.470 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 1lke | DOG | Bilin-binding protein | / | 0.469 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.469 | |
| 4avw | G18 | Tankyrase-2 | 2.4.2.30 | 0.469 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.468 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.467 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.466 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.465 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.465 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.464 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.464 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.464 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.464 | |
| 4kzl | 20D | Tankyrase-2 | 2.4.2.30 | 0.464 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.463 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.463 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4l2f | 1V3 | Tankyrase-2 | 2.4.2.30 | 0.463 | |
| 4nv0 | MG7 | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.463 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.463 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.462 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.462 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.462 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3nhr | RZW | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.461 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.461 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.460 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.460 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.460 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.459 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.459 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.459 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.458 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.458 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.458 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.458 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.457 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3f90 | FMN | Flavodoxin | / | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.457 | |
| 4j21 | AJ6 | Tankyrase-2 | 2.4.2.30 | 0.457 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.457 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.456 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.456 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.455 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.455 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.455 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.455 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.455 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.455 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.454 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.454 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.454 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.454 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4buw | F33 | Tankyrase-2 | 2.4.2.30 | 0.454 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.453 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.453 | |
| 3frk | TQP | QdtB | / | 0.453 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3lns | NAP | NAD(P)-dependent benzaldehyde dehydrogenase | 1.2.1.28 | 0.453 | |
| 3s5w | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.453 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 4kxj | P34 | Nucleoprotein | / | 0.453 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 4n1g | CEI | Obelin | / | 0.453 | |
| 4qak | 2AM | RNA 2',3'-cyclic phosphodiesterase | / | 0.453 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.452 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.452 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 4buu | F38 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.451 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.451 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 3ihk | TPP | Uncharacterized protein | / | 0.451 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.451 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.451 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4bzb | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.451 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.451 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.450 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 3pz4 | 3PZ | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.450 | |
| 1n0s | FLU | Bilin-binding protein | / | 0.449 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.449 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.449 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.449 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.449 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.448 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.448 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 2r8o | T5X | Transketolase 1 | / | 0.448 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.448 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4j22 | AJ7 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 1c3r | TSN | Acetoin utilization protein | / | 0.447 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3irh | DTP | HD domain protein | / | 0.447 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.447 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.447 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4hlg | 20B | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.446 | |
| 1gaq | FAD | Ferredoxin | / | 0.445 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.445 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.445 | |
| 2y01 | Y00 | Beta-1 adrenergic receptor | / | 0.445 | |
| 2yhu | WHF | Pteridine reductase | / | 0.445 | |
| 3a8i | C2F | Aminomethyltransferase | 2.1.2.10 | 0.445 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3v2u | ATP | Protein GAL3 | / | 0.445 | |
| 3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 4f1q | 0RZ | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.445 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.444 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.444 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.444 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.444 | |
| 4dyb | 0MH | Nucleoprotein | / | 0.444 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.444 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.444 | |
| 4l33 | F70 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.443 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.443 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.443 | |
| 3e78 | TPP | High affinity transport system protein p37 | / | 0.443 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4but | 31F | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4l8u | 9AZ | Serum albumin | / | 0.443 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.443 | |
| 1g6o | ADP | Cag alpha | / | 0.442 | |
| 1pt5 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.442 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.442 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.442 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.442 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.442 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.442 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3up3 | XCA | aceDAF-12 | / | 0.442 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4l10 | A63 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4l32 | 1VF | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.442 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.442 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.441 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.441 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.441 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.441 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.441 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.441 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.440 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1s36 | CEI | Obelin | / | 0.440 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.440 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.440 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.440 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.440 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 0.440 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.440 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.440 | |
| 3pfh | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.440 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.440 | |
| 3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.440 | |
| 4g0k | 0VS | Glutathionyl-hydroquinone reductase YqjG | 1.8 | 0.440 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.440 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.440 | |
| 4phl | PIL | Phosphodiesterase | / | 0.440 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.440 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.440 |