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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.146

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1461.000
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.584
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.575
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.574
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.565
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.558
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.554
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.552
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.549
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.545
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.539
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.519
4hx519VCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.519
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.516
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.516
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.513
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.507
2zbaZBATrichothecene 3-O-acetyltransferase/0.507
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.506
2po7CHDFerrochelatase, mitochondrial4.99.1.10.505
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.502
3vtbTKAVitamin D3 receptor/0.498
4o1mNADEnoyl-acyl carrier reductase/0.494
2aazCB3Thymidylate synthase2.1.1.450.493
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.493
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.491
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.488
1x8lOXRRetinol dehydratase/0.487
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.486
4oztP1AEcdysone receptor, putative/0.486
1kquBR4Phospholipase A2, membrane associated/0.485
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.484
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.484
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.484
3angDCCTranscriptional repressor, TetR family/0.483
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.483
4a81DXCMajor pollen allergen Bet v 1-A/0.482
1fm4DXCMajor pollen allergen Bet v 1-L/0.481
1lriCLRBeta-elicitin cryptogein/0.481
2y60M8FIsopenicillin N synthase1.21.3.10.481
3bzuA21Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.481
1cqp803Integrin alpha-L/0.480
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.479
4jx1CAHCamphor 5-monooxygenase1.14.15.10.479
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.479
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.478
1qiqACCIsopenicillin N synthase1.21.3.10.477
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.476
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.476
1xddAAYIntegrin alpha-L/0.475
3jynNDPQuinone oxidoreductase/0.475
3owuEQUSteroid Delta-isomerase5.3.3.10.475
4a83DXCMajor pollen allergen Bet v 1-A/0.475
2jb4A14Isopenicillin N synthase1.21.3.10.474
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.474
1fmlRTLRetinol dehydratase/0.473
2bu9HFVIsopenicillin N synthase1.21.3.10.473
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.473
3br3ETHTH-type transcriptional regulator QacR/0.473
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.473
4iah1DXAlr2278 protein/0.473
4mihFADPyranose 2-oxidase1.1.3.100.473
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.472
5uviZMAAdenosine receptor A2a/0.472
1e1lFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.471
2hqpNDPDihydrofolate reductase1.5.1.30.471
3zkyWT4Isopenicillin N synthase1.21.3.10.471
1hvyD16Thymidylate synthase2.1.1.450.470
2xpuTDCTetracycline repressor protein class D/0.470
4c3yFAD3-ketosteroid dehydrogenase/0.470
1xuoLA1Integrin alpha-L/0.469
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.469
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.469
4q71FADBifunctional protein PutA/0.469
4rujVDXVitamin D3 receptor A/0.469
1zdwFLVPrenyltransferase/0.468
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.468
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.468
3zoiM2WIsopenicillin N synthase1.21.3.10.468
1fmjRTLRetinol dehydratase/0.467
1hpzAAPGag-Pol polyprotein2.7.7.490.467
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.467
3vt9YI4Vitamin D3 receptor/0.467
1g6kNADGlucose 1-dehydrogenase1.1.1.470.466
1qjfACSIsopenicillin N synthase1.21.3.10.466
2aibERGBeta-elicitin cinnamomin/0.466
2wo7ASVIsopenicillin N synthase1.21.3.10.466
2xf3J01Uncharacterized protein/0.466
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.466
4eiyZMAAdenosine receptor A2a/0.466
2zevB71Geranylgeranyl pyrophosphate synthase/0.465
3h3t16HCollagen type IV alpha-3-binding protein/0.465
3pm1ETHTH-type transcriptional regulator QacR/0.465
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.465
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.465
1upw444Oxysterols receptor LXR-beta/0.464
2iviACWIsopenicillin N synthase1.21.3.10.464
3syiFADSulfide-quinone reductase/0.464
3vtdTKDVitamin D3 receptor/0.464
4o7uTHFThymidylate synthase/0.464
1hb1OCVIsopenicillin N synthase1.21.3.10.463
2fj1CTCTetracycline repressor protein class D/0.463
2vbdV10Isopenicillin N synthase1.21.3.10.463
2xlsFADPutative flavin-containing monooxygenase/0.463
3p3zP3ZPutative cytochrome P450/0.463
1kvoOAPPhospholipase A2, membrane associated/0.462
1trgCB3Thymidylate synthase/0.462
2xveFADPutative flavin-containing monooxygenase/0.462
2zb3NDPProstaglandin reductase 21.3.1.480.462
3atzFMNProstaglandin F2a synthase/0.462
3bg7FADPyranose 2-oxidase/0.462
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.462
3eksCY9Actin-5C/0.462
1osvCHCBile acid receptor/0.461
2r0pK2CPutative FAD-monooxygenase/0.461
3vt45YIVitamin D3 receptor/0.461
3w0hW12Vitamin D3 receptor/0.461
4auxXTCTetracycline repressor protein class D/0.461
4g1z0VPVitamin D3 receptor A/0.461
4z24FADPutative GMC-type oxidoreductase R13510.461
1ie8KH1Vitamin D3 receptor/0.460
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.460
1w78PD8Dihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.460
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.460
2vkeTACTetracycline repressor protein class D/0.460
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.460
3l0lHC3Nuclear receptor ROR-gamma/0.460
3oqkS52Renin3.4.23.150.460
3vt5YI2Vitamin D3 receptor/0.460
4bb3KKAIsopenicillin N synthase1.21.3.10.460
4mk728OGenome polyprotein2.7.7.480.460
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.460
1db56INPhospholipase A2, membrane associated/0.459
1tehNADAlcohol dehydrogenase class-31.1.1.10.459
1yqzCOACoenzyme A disulfide reductase/0.459
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.459
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.459
3flwFLWMitogen-activated protein kinase 14/0.459
3vt65YIVitamin D3 receptor/0.459
4c3xFAD3-ketosteroid dehydrogenase/0.459
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.458
1fwkADPHomoserine kinase2.7.1.390.458
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.458
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1s7gNADNAD-dependent protein deacylase 2/0.458
2igoFADPyranose 2-oxidase/0.458
3b9oFMNAlkane monoxygenase/0.458
3uteFADUDP-galactopyranose mutase/0.458
4fhi0S4Vitamin D3 receptor A/0.458
4itfTFYVitamin D3 receptor/0.458
4o701QKBromodomain-containing protein 4/0.458
4psbGA3Cytokinin-specific binding protein/0.458
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.458
1hb3SCVIsopenicillin N synthase1.21.3.10.457
1jtuLYBThymidylate synthase/0.457
1oc1ASVIsopenicillin N synthase1.21.3.10.457
1re9DSOCamphor 5-monooxygenase1.14.15.10.457
3k7tFAD6-hydroxy-L-nicotine oxidase/0.457
3vt7VDXVitamin D3 receptor/0.457
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.457
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.457
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.457
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.457
4g2fC07Ephrin type-A receptor 32.7.10.10.457
4l8u9AZSerum albumin/0.457
5fm7ADPRuvB-like helicase/0.457
5jscFADPutative acyl-CoA dehydrogenase/0.457
5k2dZMAAdenosine receptor A2a/0.457
1bk0ACVIsopenicillin N synthase1.21.3.10.456
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1rf9DBRCamphor 5-monooxygenase1.14.15.10.456
1thnADPAnti-sigma F factor/0.456
1w6hTITPlasmepsin-23.4.23.390.456
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
2dteNAIGlucose 1-dehydrogenase related protein/0.456
2nn7M29Carbonic anhydrase 14.2.1.10.456
2zl9VDAVitamin D3 receptor/0.456
3ekuCY9Actin-5C/0.456
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.456
4jjiNADAlcohol dehydrogenase class-3/0.456
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.455
1r2jFADFkbI/0.455
1z7yAA5Cysteine synthase 12.5.1.470.455
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.455
2xaaNADSecondary alcohol dehydrogenase/0.455
4tuvCPZCytochrome P450 1191.140.455
1ia4TQ6Dihydrofolate reductase1.5.1.30.454
1xe55FEPlasmepsin-23.4.23.390.454
2bgjFADNADPH:ferredoxin reductase/0.454
2ignFADPyranose 2-oxidase/0.454
2yekEAMBromodomain-containing protein 2/0.454
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.454
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.454
3ha5SFGHydroxymycolate synthase MmaA42.1.10.454
3lshFADPyranose 2-oxidase/0.454
3pm9FADPutative oxidoreductase/0.454
3up3XCAaceDAF-12/0.454
4eqsCOACoenzyme A disulfide reductase/0.454
4g3jVNTLanosterol 14-alpha-demethylase/0.454
4ia7BIVVitamin D3 receptor A/0.454
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.453
1qvnFRIInterleukin-2/0.453
1rkhVD2Vitamin D3 receptor/0.453
1swtBTNStreptavidin/0.453
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.453
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2hw2RFPRifampin ADP-ribosyl transferase/0.453
2w4qCBWProstaglandin reductase 21.3.1.480.453
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.453
3c3xNAPEugenol synthase 11.1.1.3180.453
3gw9VNILanosterol 14-alpha-demethylase/0.453
3up0D7SaceDAF-12/0.453
4ambDUDPutative glycosyl transferase/0.453
4gdeFDAUDP-galactopyranose mutase/0.453
4iaq2GM5-hydroxytryptamine receptor 1B/0.453
4ruoBIVVitamin D3 receptor A/0.453
4yaoFMNNADPH--cytochrome P450 reductase/0.453
5k2bZMAAdenosine receptor A2a/0.453
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.452
2bjfDXCCholoylglycine hydrolase3.5.1.240.452
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.452
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.452
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.452
3l6jZ90Alr2278 protein/0.452
3t2zFADSulfide-quinone reductase/0.452
4jqh1MFAlr2278 protein/0.452
4u9vACON-alpha-acetyltransferase 402.3.10.452
4wx1FDAUDP-galactopyranose mutase/0.452
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.452
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.452
1ia1NDPDihydrofolate reductase1.5.1.30.451
1iyzNDPProbable quinone oxidoreductase/0.451
1kceCB3Thymidylate synthase/0.451
1pr9NAPL-xylulose reductase1.1.1.100.451
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.451
2cduFADNADH oxidase/0.451
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.451
2rm2W43Genome polyprotein/0.451
3qwbNDPProbable quinone oxidoreductase1.6.5.50.451
3rm618ZCyclin-dependent kinase 22.7.11.220.451
3sz0FADSulfide-quinone reductase/0.451
3ukkFADUDP-galactopyranose mutase/0.451
3w0iO11Vitamin D3 receptor/0.451
4fxfATPPyruvate kinase PKM2.7.1.400.451
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4klaCHDFerrochelatase, mitochondrial4.99.1.10.451
4udrFAD5-(hydroxymethyl)furfural oxidase/0.451
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
1qo8FADFumarate reductase flavoprotein subunit/0.450
2akoADPGlutamate 5-kinase/0.450
2c0cNAPProstaglandin reductase 310.450
2hcdBIVVitamin D3 receptor A/0.450
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.450
2nq8ZIDEnoyl-ACP reductase/0.450
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
2zb8IMNProstaglandin reductase 21.3.1.480.450
2zynBCDPeriplasmic binding protein/0.450
3lkhLT6Genome polyprotein2.7.7.480.450
3sf6FDAGlutaryl-CoA dehydrogenase/0.450
3vrtYS2Vitamin D3 receptor/0.450
4ez8DHFThymidylate synthase2.1.1.450.450
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.450
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.450
4i2q1BTGag-Pol polyprotein2.7.7.490.450
4qmySTUSerine/threonine-protein kinase 242.7.11.10.450
4rvgTYDD-mycarose 3-C-methyltransferase/0.450
1s19MC9Vitamin D3 receptor/0.449
1v35NAIEnoyl-ACP reductase/0.449
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.449
2gvcFADThiol-specific monooxygenase1.14.130.449
2o4rVD5Vitamin D3 receptor/0.449
2vceU2FUDP-glycosyltransferase 72B1/0.449
2xvfFADPutative flavin-containing monooxygenase/0.449
3lu8IQXSerum albumin/0.449
4bvaT3Ketimine reductase mu-crystallin1.5.1.250.449
4g1y0VOVitamin D3 receptor A/0.449
4iae1DXAlr2278 protein/0.449
4jx1CAMCamphor 5-monooxygenase1.14.15.10.449
4uugPXGBranched-chain amino acid aminotransferase, putative/0.449
4uyg73BBromodomain-containing protein 2/0.449
5dp2NAPCurF/0.449
5hs1VORLanosterol 14-alpha demethylase/0.449
5jlaNADPutative short-chain dehydrogenase/reductase/0.449
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.448
1c2tGARPhosphoribosylglycinamide formyltransferase/0.448
1hfqMOTDihydrofolate reductase1.5.1.30.448
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
2ylxFADPhenylacetone monooxygenase1.14.13.920.448
3anpDCCTranscriptional repressor, TetR family/0.448
3b6zCO7Enoyl reductase LovC10.448
3nx4NAPPutative oxidoreductase/0.448
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
3p6oETGCamphor 5-monooxygenase1.14.15.10.448
3p8jFMNPentaerythritol tetranitrate reductase/0.448
3t2kFADSulfide-quinone reductase/0.448
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.448
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.448
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.448
4ia3BIVVitamin D3 receptor A/0.448
4jlm1NNDeoxycytidine kinase2.7.1.740.448
4k6fNAPPutative Acetoacetyl-CoA reductase/0.448
4q73FADBifunctional protein PutA/0.448
4twnB96Ephrin type-A receptor 32.7.10.10.448
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.448
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.448
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1ml6GBXGlutathione S-transferase A22.5.1.180.447
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.447
2x9dITCTetracycline repressor protein class D/0.447
2zlaVDBVitamin D3 receptor/0.447
3bhrTHGThymidylate synthase/0.447
3ghvGHCDihydrofolate reductase1.5.1.30.447
3h3r14HCollagen type IV alpha-3-binding protein/0.447
3h3sH15Collagen type IV alpha-3-binding protein/0.447
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
3mb601ICasein kinase II subunit alpha2.7.11.10.447
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.447
3p8z36AGenome polyprotein2.1.1.560.447
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.447
4eqrCOACoenzyme A disulfide reductase/0.447
4ia1BIVVitamin D3 receptor A/0.447
4iarERM5-hydroxytryptamine receptor 1B/0.447
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.447
1aj8COACitrate synthase/0.446
1kzjCB3Thymidylate synthase/0.446
1pq944BOxysterols receptor LXR-beta/0.446
1rrmAPRLactaldehyde reductase1.1.1.770.446
2xviFADPutative flavin-containing monooxygenase/0.446
3bgrT27Gag-Pol polyprotein2.7.7.490.446
3kpkFADSulfide-quinone reductase/0.446
3oibFDAPutative acyl-CoA dehydrogenase/0.446
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.446
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.446
3t14FADSulfide-quinone reductase/0.446
3uylTYDProbable NDP-rhamnosyltransferase/0.446
3v2uATPProtein GAL3/0.446
4hwkNAPSepiapterin reductase1.1.1.1530.446
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4u8iFDAUDP-galactopyranose mutase/0.446
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.446
4y9uNAPNADPH--cytochrome P450 reductase/0.446
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.446
1ot7IU5Bile acid receptor/0.445
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.445
3da1FADGlycerol-3-phosphate dehydrogenase/0.445
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.445
3lpfZ77Beta-glucuronidase3.2.1.310.445
3lqfNADGalactitol dehydrogenase/0.445
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.445
3sglFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.445
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.445
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.445
4dbzNDPPutative ketoacyl reductase1.3.10.445
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4hyf1AKTankyrase-22.4.2.300.445
4ia2BIVVitamin D3 receptor A/0.445
4rupH97Vitamin D3 receptor A/0.445
1blzACVIsopenicillin N synthase1.21.3.10.444
1dnaCB3Thymidylate synthase/0.444
1dr3TAPDihydrofolate reductase1.5.1.30.444
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.444
1w06W05Isopenicillin N synthase1.21.3.10.444
2ftoTMPThymidylate synthase/0.444
2gv8NDPThiol-specific monooxygenase1.14.130.444
2ociTYCValacyclovir hydrolase3.10.444
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.444
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
2tctCTCTetracycline repressor protein class D/0.444
2vcmM11Isopenicillin N synthase1.21.3.10.444
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.444
3aosJH2Hemolymph juvenile hormone binding protein/0.444
3jzdNADMaleylacetate reductase/0.444
3kytHC2Nuclear receptor ROR-gamma/0.444
3p8zSAHGenome polyprotein2.1.1.560.444
3p99LNPLanosterol 14-alpha-demethylase/0.444
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.444
3uwlFOZThymidylate synthase/0.444
3vruYS3Vitamin D3 receptor/0.444
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.444
4at0FADPossible succinate dehydrogenase/0.444
4jtrIZPAldo-keto reductase family 1 member C2/0.444
4mv1ADPBiotin carboxylase6.3.4.140.444
4u2lSFDCholesterol oxidase1.1.3.60.444
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.444
3sn6P0GBeta-2 adrenergic receptor/0.444
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1mczRMNBenzoylformate decarboxylase4.1.1.70.443
1q23FUAChloramphenicol acetyltransferase2.3.1.280.443
1z4uPH9Polyprotein/0.443
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.443
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
2o7pNAPRiboflavin biosynthesis protein RibD/0.443
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
2xvhFADPutative flavin-containing monooxygenase/0.443
2y6fM9FIsopenicillin N synthase1.21.3.10.443
3is9AC7Gag-Pol polyprotein2.7.7.490.443
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.443
3w0gW07Vitamin D3 receptor/0.443
4nbwNADShort-chain dehydrogenase/reductase SDR/0.443
4nmdFDABifunctional protein PutA/0.443
4qi5FADCellobiose dehydrogenase/0.443
5cyqT27Gag-Pol polyprotein2.7.7.490.443
5d1bTSNHistone deacetylase 83.5.1.980.443
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.443
5k2cZMAAdenosine receptor A2a/0.443
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.442
1g6oADPCag alpha/0.442
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.442
1pdhFASp-hydroxybenzoate hydroxylase/0.442
1poxFADPyruvate oxidase1.2.3.30.442
1tduDURThymidylate synthase/0.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.442
3b8z294A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.442
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.442
3cvkN34Genome polyprotein2.7.7.480.442
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.442
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3mqe416Prostaglandin G/H synthase 21.14.99.10.442
3tfyCOAN-alpha-acetyltransferase 502.3.10.442
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.442
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.442
3vrwYS5Vitamin D3 receptor/0.442
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.442
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.442
4dc0NDPPutative ketoacyl reductase1.3.10.442
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.442
4ipw1G7Mycocyclosin synthase1.14.21.90.442
4nieNBHNuclear receptor ROR-gamma/0.442
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.442
1dv2ATPBiotin carboxylase6.3.4.140.441
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1pqc444Oxysterols receptor LXR-beta/0.441
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.441
1tw4CHDFatty acid-binding protein, liver/0.441
1tysDHFThymidylate synthase/0.441
2c29NAPDihydroflavonol 4-reductase/0.441
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.441
2cig1DGDihydrofolate reductase1.5.1.30.441
2qo9ANPEphrin type-A receptor 32.7.10.10.441
3gobHXXDdmC/0.441
3linE13Protease/0.441
3s5wNAPL-ornithine N(5)-monooxygenase/0.441
3tm5SFGUncharacterized protein/0.441
3vt3VDXVitamin D3 receptor/0.441
4b3aTACTetracycline repressor protein class D/0.441
4coxIMNProstaglandin G/H synthase 21.14.99.10.441
4g95OAGDihydrofolate reductase1.5.1.30.441
4mk928RGenome polyprotein2.7.7.480.441
4nb6444Nuclear receptor ROR-gamma/0.441
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.441
4uymVOR14-alpha sterol demethylase Cyp51B/0.441
5hsaFASAlcohol oxidase 11.1.3.130.441
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.441
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.440
1me6IVSPlasmepsin-23.4.23.390.440
1p8dCO1Oxysterols receptor LXR-beta/0.440
1txiTX5Vitamin D3 receptor/0.440
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.440
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.440
2ft9CHDFatty acid-binding protein 2, liver/0.440
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.440
2qimZEAClass 10 plant pathogenesis-related protein/0.440
2rc6NAPFerredoxin--NADP reductase/0.440
3a783EVVitamin D3 receptor/0.440
3d7kD7KBenzaldehyde lyase/0.440
3ds6A17Mitogen-activated protein kinase 14/0.440
3dxmN24Actin-related protein 3/0.440
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.440
3lfeZ84Mitogen-activated protein kinase 14/0.440
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.440
3qlrNDPDihydrofolate reductase1.5.1.30.440
3slkNDPPolyketide synthase extender module 2/0.440
3ukkFDAUDP-galactopyranose mutase/0.440
3uklFADUDP-galactopyranose mutase/0.440
3vtcTK3Vitamin D3 receptor/0.440
3w5p4OAVitamin D3 receptor/0.440
4b1rITCTetracycline repressor protein class D/0.440
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.440
4iteTEYVitamin D3 receptor/0.440
4jq3ZOMAldo-keto reductase family 1 member C2/0.440
4li61XOTankyrase-12.4.2.300.440
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
5dcyNAPIridoid synthase1.3.1.990.440
5iubCLRAdenosine receptor A2a/0.440