Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2bwg | 5GP | GMP reductase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2bwg | 5GP | GMP reductase 1 | / | 1.000 | |
| 2ble | 5GP | GMP reductase 1 | / | 0.616 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.550 | |
| 2cu0 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.539 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.518 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.506 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.498 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.496 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.494 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.492 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.492 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.489 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.489 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.488 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.486 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.480 | |
| 1iy8 | NAD | Levodione reductase | / | 0.480 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.478 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.478 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.475 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.475 | |
| 1me7 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.475 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.475 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.475 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.474 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.474 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.473 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.472 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.472 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.472 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.472 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.471 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.471 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.471 | |
| 1hld | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.470 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.470 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.470 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.470 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.470 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.470 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.470 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.470 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.469 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.469 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.469 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.469 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.468 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.468 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.468 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.467 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.467 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.467 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.466 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.465 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.465 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.465 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.464 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.464 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.464 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.464 | |
| 4j4b | NAI | Uncharacterized protein | / | 0.464 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.463 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.463 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 2oxt | SAM | Genome polyprotein | / | 0.462 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.462 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.462 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.462 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.462 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.461 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.460 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.460 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.460 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.459 | |
| 1mgo | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 1p0f | NAP | NADP-dependent alcohol dehydrogenase | 1.1.1.2 | 0.459 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.459 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.459 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.459 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.459 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.459 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.458 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.458 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.458 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.458 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.458 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.458 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.458 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.457 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.456 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 2wa2 | SAM | Genome polyprotein | / | 0.456 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.456 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.456 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.456 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.456 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.456 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.456 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.455 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.455 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.455 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.455 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.455 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.455 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.455 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.455 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.455 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.454 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.454 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.454 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.454 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.454 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.454 | |
| 1kqg | HQO | Formate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit | / | 0.453 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.453 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.453 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.453 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.452 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.452 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.452 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.452 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.452 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.452 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.452 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.452 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.452 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.452 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.451 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.451 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.451 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2oxi | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.451 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.451 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.451 | |
| 3zuy | TCH | Transporter | / | 0.451 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.451 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.451 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.450 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.450 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.450 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.450 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.450 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.449 | |
| 1ja1 | NAP | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1zq9 | SAM | Probable dimethyladenosine transferase | / | 0.449 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.449 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.449 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.449 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.449 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.449 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.449 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.448 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.448 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.448 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.448 | |
| 1r2j | FAD | FkbI | / | 0.448 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.448 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.448 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3eks | CY9 | Actin-5C | / | 0.448 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.448 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.448 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.448 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.448 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.448 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.448 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.448 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.447 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1ppj | ANY | Cytochrome b | / | 0.447 | |
| 1u3v | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.447 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.447 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.447 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.447 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.447 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.447 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.447 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.447 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.447 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.447 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.447 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.447 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.446 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.446 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.446 | |
| 1rc1 | KT3 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.446 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.446 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.446 | |
| 3ieu | GDP | GTPase Era | / | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.446 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.446 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.446 | |
| 4jlo | ADP | Adenylate kinase | / | 0.446 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.446 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.445 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.445 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.445 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.445 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.445 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.445 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.445 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.445 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.445 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.444 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.444 | |
| 1osv | CHC | Bile acid receptor | / | 0.444 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.444 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.444 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.444 | |
| 2nad | NAD | Formate dehydrogenase | / | 0.444 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.444 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.444 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.443 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.443 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.443 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.443 | |
| 3a1e | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.443 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.443 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.443 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.443 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.443 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.443 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.443 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.443 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.442 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.442 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.442 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.442 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.442 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.442 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.442 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.441 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.441 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.441 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.441 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.441 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.441 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.441 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.441 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.441 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.441 | |
| 3gob | HXX | DdmC | / | 0.441 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.441 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.441 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.441 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.441 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.441 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.441 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.440 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.440 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.440 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.440 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.440 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.440 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.440 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.440 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.440 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.440 | |
| 3oq6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.440 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.440 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.440 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |