sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 1.000 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.532 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.506 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.500 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.492 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.487 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.487 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.486 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.484 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.481 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.480 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.480 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.480 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.480 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.480 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.479 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.478 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.478 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.478 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.478 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.477 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.476 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.473 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.473 | |
| 3ieu | GDP | GTPase Era | / | 0.473 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.473 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.472 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.472 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.472 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.472 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.471 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.470 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.470 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.470 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.470 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.470 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.469 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.468 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.467 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.467 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.467 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.466 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.466 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.466 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.466 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.465 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.465 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.465 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.464 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.464 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.464 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.464 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.464 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.464 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.463 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.463 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.463 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.463 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.463 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.463 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.463 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.462 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.462 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.462 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.461 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.461 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.461 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 1h72 | ANP | Homoserine kinase | 2.7.1.39 | 0.459 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.459 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.459 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.459 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.459 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.458 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.458 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.458 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.457 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.457 | |
| 2ohv | NHL | Glutamate racemase | / | 0.457 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.457 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.457 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.456 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.456 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.456 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.456 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.456 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.455 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.455 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.455 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.455 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.455 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.454 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.454 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.454 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.454 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.454 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.454 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.453 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.453 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.453 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.453 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.453 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.453 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.453 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.453 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.453 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.453 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.452 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3fst | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.452 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.452 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.452 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.452 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.452 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.451 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.451 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.451 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.450 | |
| 1glf | ADP | Glycerol kinase | / | 0.450 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.450 | |
| 3eks | CY9 | Actin-5C | / | 0.450 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.450 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.449 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.449 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.449 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.449 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.449 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.449 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.449 | |
| 4c4o | NAD | SADH | / | 0.449 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.449 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.449 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.448 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.448 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.448 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.448 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.448 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.447 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.447 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.447 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.447 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.446 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.446 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.446 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.446 | |
| 3r96 | ACO | MccE protein | / | 0.446 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.446 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.446 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.446 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.445 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.445 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.445 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.445 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.444 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.443 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.443 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.443 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.443 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.443 | |
| 3v2u | ATP | Protein GAL3 | / | 0.443 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.443 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.443 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.443 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.442 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.442 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.442 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 2y3r | TRK | TamL | / | 0.442 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.442 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.442 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.442 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.442 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.441 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.441 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.441 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.441 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.441 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.441 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.441 | |
| 5c41 | ACP | Ribokinase | / | 0.441 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.440 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.440 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.440 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.440 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.440 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.440 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 |