sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.874 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.831 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.822 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.811 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.802 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.795 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.791 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.771 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.769 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.599 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.577 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.577 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.575 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.574 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.562 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.557 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.554 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.553 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.547 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.546 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.543 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.537 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.536 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.534 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.521 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.513 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.513 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.512 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.510 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.509 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.504 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.499 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.499 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.495 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.487 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.487 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.487 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.486 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.483 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.482 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.481 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.481 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.479 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.478 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.478 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.476 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.476 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.475 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.474 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.473 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.473 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.473 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.472 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.471 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.470 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.469 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.469 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.468 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.468 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.466 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.465 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.465 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 4iae | 1DX | Alr2278 protein | / | 0.465 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.463 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.463 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.463 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.463 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.463 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.462 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.462 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.462 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.461 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4boe | CLR | Japanin | / | 0.461 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.461 | |
| 5doz | NDP | JamJ | / | 0.461 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.460 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.460 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.460 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.460 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.459 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.459 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.458 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.458 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.458 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.457 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.457 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.457 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.457 | |
| 4iah | 1DX | Alr2278 protein | / | 0.457 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.457 | |
| 4u7w | NDP | MxaA | / | 0.457 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.456 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.456 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.456 | |
| 4jic | FMN | GTN Reductase | / | 0.456 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.455 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.455 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.455 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.455 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.455 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.455 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.455 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.454 | |
| 3a6r | FMN | FMN-binding protein | / | 0.454 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.454 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.453 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.453 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.453 | |
| 4n1g | CEI | Obelin | / | 0.453 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.453 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.453 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.452 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.452 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.452 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.451 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.451 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.451 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.451 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.451 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.451 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.450 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.450 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.449 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.449 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.449 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.447 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.447 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.447 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.447 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.447 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.447 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 1m9t | INE | Nitric oxide synthase, inducible | 1.14.13.39 | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.446 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.446 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.445 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.445 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.445 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3eku | CY9 | Actin-5C | / | 0.445 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.445 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.445 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.445 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.445 | |
| 4pgt | GBX | Glutathione S-transferase P | 2.5.1.18 | 0.445 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
| 4xr9 | NAD | CalS8 | / | 0.445 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.445 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.444 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.444 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.444 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.444 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.443 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.443 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.443 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3v2u | ATP | Protein GAL3 | / | 0.443 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.443 | |
| 4ohx | ADP | Protein clpf-1 | / | 0.443 | |
| 4xwt | U5P | Ribonuclease J | / | 0.443 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.442 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.442 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.442 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.442 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.441 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.441 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.441 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3eej | 53R | Uncharacterized protein | / | 0.441 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.441 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.441 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.441 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.440 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.440 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 5ftc | ADP | TPR domain protein | / | 0.440 |